3FEX

crystal structure of the cbc-importin alpha complex.

• Total interactions analyzed: 3
• Total true interactions: 2
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 148
  • Norm. En. per Res.: -4.6269
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-20.2019	-81.6484	-268.623	-370.4733	115	12	4	12041	5	62	54
A-C	-147.9428	-126.9925	-409.841	-684.7763	148	21	0	14484	13	60	55

Interface residues

• A-B: ALA556A, ALA602A, ALA92B, ALA97B, ARG105B, ARG109B, ARG112B, ARG329A, ARG412A, ARG427A, ARG458A, ARG464A, ARG610A, ARG646A, ARG99B, ASN102B, ASN415A, ASN423A, ASN96B, ASP107B, ASP108B, ASP369A, ASP606A, ASP65B, ASP93B, CYS332A, CYS456A, GLN425A, GLN55B, GLN599A, GLU328A, GLU378A, GLU454A, GLU53B, GLU54B, GLU58B, GLU639A, GLU87B, GLU95B, GLY103B, GLY64B, HIS325A, HIS367A, HIS419A, HIS420A, HIS561A, HIS597A, HIS642A, ILE101B, ILE110B, ILE111B, ILE322A, ILE368A, ILE377A, ILE414A, ILE56B, ILE66B, ILE69B, ILE70B, LEU106B, LEU375A, LEU421A, LEU459A, LEU59B, LYS327A, LYS330A, LYS381A, LYS455A, LYS557A, LYS607A, LYS62B, LYS647A, LYS650A, LYS654A, LYS67B, LYS68B, MET371A, MET457A, MET600A, MET71B, MET98B, PHE424A, PHE426A, PHE559A, PHE563A, PHE60B, PRO481A, SER418A, SER422A, SER460A, SER558A, SER560A, SER564A, SER61B, SER63B, SER643A, SER90B, THR104B, THR113B, THR373A, THR374A, THR51B, THR52B, THR611A, THR644A, TRP326A, TRP416A, TYR100B, TYR372A, TYR461A, TYR50B, TYR57B, TYR89B, VAL370A, VAL603A
• A-C: ALA143C, ALA148C, ALA176C, ALA185C, ALA190C, ALA24A, ALA269C, ALA364C, ALA397C, ALA400C, ARG101C, ARG106C, ARG18A, ARG19A, ARG227C, ARG238C, ARG315C, ARG366C, ARG3A, ARG4A, ARG5A, ASN10A, ASN146C, ASN188C, ASN228C, ASN235C, ASN239C, ASN241C, ASN25A, ASN283C, ASN319C, ASN350C, ASN361C, ASN403C, ASN446C, ASP11A, ASP192C, ASP23A, ASP270C, ASP280C, ASP325C, ASP8A, GLN109C, GLN14A, GLN154C, GLN181C, GLN327C, GLN329C, GLN369C, GLN394C, GLN98C, GLU107C, GLU139C, GLU153C, GLU180C, GLU26A, GLU326C, GLU354C, GLU396C, GLU9A, GLY12A, GLY13A, GLY150C, GLY187C, GLY191C, GLY193C, GLY224C, GLY281C, GLY318C, GLY323C, GLY365C, GLY407C, HIS16A, HIS177C, HIS6A, ILE112C, ILE147C, ILE178C, ILE189C, ILE286C, ILE320C, ILE332C, ILE362C, ILE370C, ILE436C, LEU103C, LEU104C, LEU229C, LEU314C, LYS102C, LYS108C, LYS156C, LYS17A, LYS20A, LYS240C, LYS353C, LYS392C, LYS395C, LYS435C, MET359C, PHE138C, PHE196C, PRO110C, PRO111C, PRO15A, PRO282C, PRO308C, PRO312C, SER105C, SER149C, SER152C, SER22A, SER234C, SER276C, SER2A, SER360C, SER406C, SER7A, THR145C, THR151C, THR155C, THR21A, THR230C, THR232C, THR27A, THR311C, THR322C, THR324C, THR328C, THR356C, THR358C, THR363C, THR402C, THR73C, TRP142C, TRP184C, TRP231C, TRP273C, TRP357C, TRP399C, TYR225C, TYR277C, TYR404C, VAL183C, VAL321C, VAL398C, VAL401C, VAL439C