3FAT

x-ray structure of iglur4 flip ligand-binding core (s1s2) in complex with (s)-ampa at 1.90a resolution

• Total interactions analyzed: 3
• Total true interactions: 3
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 67
  • Norm. En. per Res.: -2.9926
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-52.3913	-9.3522	579.996	518.2525	117	48	4	9225	3	48	40
A-C	0.0	7.3112	-55.3297	-48.0185	48	1	2	2610	0	13	15
B-C	-21.8817	-22.4972	-156.127	-200.5059	67	6	1	7211	2	47	43

Interface residues

• A-B: ALA221A, ALA221B, ALA235A, ALA235B, ALA242A, ALA242B, ALA38A, ALA42A, ARG147A, ARG147B, ARG229A, ARG229B, ARG94A, ARG94B, ASN233A, ASN233B, ASP214A, ASP214B, ASP246A, ASP246B, ASP99A, ASP99B, GLU143A, GLU143B, GLU241A, GLU241B, GLU40A, GLU95A, GLU95B, GLU96A, GLU96B, GLY217A, GLY217B, GLY219A, GLY219B, GLY243A, GLY243B, GLY46A, HIS44A, ILE150A, ILE150B, ILE41A, ILE45A, ILE47A, ILE90A, ILE90B, ILE98A, ILE98B, ILE9B, LEU213A, LEU213B, LEU234A, LEU234B, LEU237A, LEU237B, LEU239A, LEU239B, LEU245A, LEU245B, LEU37A, LEU92A, LEU92B, LYS102A, LYS102B, LYS149A, LYS149B, LYS216A, LYS216B, LYS224A, LYS224B, LYS238A, LYS238B, LYS247A, LYS247B, LYS43A, MET105A, MET105B, PHE100A, PHE100B, PHE144A, PHE144B, PRO103A, PRO103B, PRO231A, PRO231B, SER101A, SER101B, SER106A, SER106B, SER140A, SER140B, SER148A, SER148B, SER215A, SER215B, SER240A, SER240B, SER39A, THR230A, THR230B, THR89A, THR89B, THR91A, THR91B, TYR153A, TYR218A, TYR218B, VAL220A, VAL220B, VAL232A, VAL236A, VAL236B, VAL244B, VAL93A, VAL93B, VAL97A, VAL97B
• A-C: ALA235A, ALA242A, ALA42A, ALA81C, ARG2A, ARG2A9, ARG2C, ASN233A, ASN70C, CB7.7392620.06868, GLU241A, GLU75C, GLU82C, GLY1A, GLY225C, GLY46A, GLY74C, GLY79C, HIS44A, ILE41A, ILE45A, ILE47A, ILE68C, LEU228A, LEU234A, LEU237A, LEU239A, LEU76C, LYS224C, LYS238A, LYS43A, LYS50C, LYS67C, LYS80C, PRO223C, PRO231A, SER226C, SER227A, SER227C, THR230A, THR3C, THR66C, TRP69C, TYR78C, VAL232A, VAL5C, VAL77C, VAL97C
• B-C: ALA61B, ALA61C, ALA64B, ALA64C, ARG146B, ARG146C, ARG147B, ARG147C, ARG161B, ARG161C, ARG229B, ARG62B, ARG62C, ARG94B, ARG94C, ASP63B, ASP63C, ASP65B, ASP65C, GLU143B, GLU143C, GLU95B, GLU95C, GLU96B, GLU96C, GLY225B, GLY225C, GLY74B, GLY74C, ILE68B, ILE68C, ILE98B, ILE98C, ILE9B, LEU92B, LEU92C, LYS142B, LYS142C, LYS149B, LYS149C, LYS224B, LYS224C, LYS67B, LYS67C, LYS80C, PHE144B, PHE144C, PHE145B, PHE145C, SER148B, SER148C, THR66B, THR66C, THR91B, THR91C, TRP157B, TRP157C, TRP69B, TRP69C, TYR78B, TYR78C, VAL77B, VAL77C, VAL93B, VAL93C, VAL97B, VAL97C