3F9Y

structural insights into lysine multiple methylation by set domain methyltransferases, set8-y334f / h4-lys20me1 / adohcy

• Total interactions analyzed: 6
• Total true interactions: 4
• Strongest Interaction:
  • Chains: A-E
  • Int. Res.: 61
  • Norm. En. per Res.: -4.5942
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-33.1612	-13.3251	-124.616	-171.1023	68	7	2	5721	2	28	32
A-E	-62.0061	-33.4801	-184.758	-280.2441	61	10	5	6752	1	21	28
A-F	0.0	0.0	-24.5217	-24.5217	20	1	1	1232	1	8	11
B-F	-53.8369	-43.9563	-173.674	-271.4672	61	7	5	6494	2	22	32

Interface residues

• A-B: ALA255B, ALA342B, ARG228A, ARG238B, ARG288A, ARG292A, ARG295A, ARG339B, ASN291A, ASN298A, ASP221A, ASP224A, ASP265A, ASP335B, ASP338B, CYS283B, CYS302B, GLN264A, GLN276B, GLN306B, GLU215A, GLU216A, GLU251B, GLU259B, GLU289A, GLY213A, GLY225A, GLY227A, GLY229A, GLY337B, ILE220A, ILE223A, ILE231A, ILE252B, ILE344B, LEU222A, LEU278B, LEU293A, LEU296A, LEU350B, LYS214A, LYS219A, LYS226A, LYS256B, LYS280B, LYS301B, LYS308B, LYS341B, LYS351B, MET218A, MET272B, PHE275B, PRO266A, PRO348A, SER267A, SER279B, SER340B, SER343B, THR253B, THR281B, THR290A, THR307B, TRP349A, TYR273B, TYR274B, TYR277B, TYR282B, TYR336B
• A-E: ALA255A, ALA260A, ALA263A, ALA342A, ALA346A, ARG17E, ARG19E, ARG258A, ARG339A, ASN298A, ASP265A, ASP285A, ASP335A, ASP338A, CYS270A, CYS283A, GLN264A, GLN276A, GLN306A, GLU259A, GLU345A, GLY269A, GLY337A, HIS18E, HIS299A, HIS310A, HIS317A, HIS347A, ILE252A, ILE319A, ILE344A, LEU22E, LEU261A, LEU309A, LEU318A, LEU350A, LYS16E, LYS308A, LYS341A, MET272A, PHE275A, PHE334A, PRO266A, PRO316A, PRO348A, SER267A, SER340A, SER343A, THR268A, THR281A, THR287A, THR307A, TRP349A, TYR262A, TYR271A, TYR273A, TYR274A, TYR277A, TYR282A, TYR336A, VAL21E
• A-F: ARG19F, ARG228A, ARG23F, ARG295A, ASP221A, GLU289A, GLY227A, GLY229A, GLY269A, ILE220A, ILE223A, LEU222A, LEU22F, LEU296A, LYS219A, PRO266A, SER267A, THR268A, TYR271A, VAL21F
• B-F: ALA255B, ALA260B, ALA263B, ALA342B, ALA346B, ARG17F, ARG19F, ARG23F, ARG258B, ARG339B, ASN298B, ASP265B, ASP285B, ASP335B, ASP338B, CYS270B, CYS283B, GLN264B, GLN276B, GLN306B, GLU259B, GLU345B, GLY269B, GLY337B, HIS18F, HIS299B, HIS310B, HIS317B, HIS347B, ILE252B, ILE319B, ILE344B, LEU22F, LEU261B, LEU309B, LEU318B, LEU320B, LEU350B, LYS16F, LYS256B, LYS308B, MET272B, PHE275B, PHE334B, PRO266B, SER267B, SER340B, SER343B, THR268B, THR281B, THR287B, THR307B, TRP349B, TYR262B, TYR271B, TYR273B, TYR274B, TYR277B, TYR282B, TYR336B, VAL21F