3E3N

the glycogen phosphorylase b r state- amp complex

• Total interactions analyzed: 28
• Total true interactions: 16
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 231
  • Norm. En. per Res.: -3.3711
• Hub Node: B(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-75.2383	-40.0061	-663.482	-778.7264	231	31	12	28795	5	85	124
A-C	0.0	11.718	-30.1686	-18.4506	39	1	0	1931	0	8	9
A-D	-9.4042	-51.0958	-137.016	-197.5161	113	8	0	5952	2	63	61
A-G	0.0	0.0	-0.2792	-0.2792	6	0	0	99	0	0	0
B-C	0.0	-68.8448	-132.552	-201.3968	110	5	0	5898	2	69	61
B-D	0.0	-11.3041	-26.5597	-37.8638	38	0	0	1624	0	8	8
B-E	-10.2064	13.0992	-85.54	-82.6472	53	5	0	3416	0	34	29
B-F	0.0	4.3759	-45.3454	-40.9695	40	4	0	1991	0	18	19
B-G	-8.9815	3.6328	-59.1914	-64.5401	53	1	2	3015	0	20	22
C-D	-50.4725	-17.9774	-620.385	-688.8349	228	24	13	27790	5	79	112
E-F	-78.7268	-39.1261	-638.502	-756.3549	227	29	13	27506	6	83	116
E-G	0.0	-12.9729	-28.7383	-41.7112	42	0	0	1874	0	8	8
E-H	-3.3486	-43.7813	-63.9761	-111.106	81	6	0	2684	2	23	19
F-G	-8.2195	-37.8127	-140.194	-186.2262	112	5	0	6187	1	65	64
F-H	0.0	8.8538	-33.6408	-24.787	44	0	0	1923	0	8	8
G-H	-53.3708	-23.1917	-670.259	-746.8216	231	21	12	29111	4	85	125

Interface residues

• A-B: ALA111A, ALA111B, ALA179A, ALA179B, ALA192A, ALA192B, ALA19A, ALA19B, ALA248B, ALA265A, ALA265B, ALA46A, ALA46B, ALA54A, ALA54B, ARG10A, ARG10B, ARG16A, ARG16B, ARG184A, ARG184B, ARG193A, ARG193B, ARG242A, ARG242B, ARG269A, ARG269B, ARG277A, ARG277B, ARG309A, ARG309B, ARG319A, ARG319B, ARG33A, ARG33B, ARG43A, ARG43B, ARG49A, ARG49B, ARG60A, ARG60B, ARG66A, ARG66B, ARG69A, ARG69B, ASN250A, ASN250B, ASN270A, ASN270B, ASN274A, ASN274B, ASN30A, ASN30B, ASN32A, ASN32B, ASN44A, ASN44B, ASP118A, ASP118B, ASP181A, ASP181B, ASP227A, ASP227B, ASP268A, ASP268B, ASP42A, ASP42B, ASP50A, ASP50B, ASP61A, ASP61B, CYS318A, CYS318B, GLN114A, GLN114B, GLN12A, GLN12B, GLN264B, GLN71A, GLN71B, GLN72A, GLN72B, GLN7A, GLN7B, GLU110A, GLU110B, GLU121A, GLU121B, GLU162A, GLU162B, GLU190A, GLU190B, GLU195A, GLU195B, GLU26A, GLU26B, GLU273A, GLU273B, GLU8A, GLU8B, GLY116A, GLY116B, GLY17A, GLY17B, GLY186A, GLY186B, GLY20A, GLY20B, GLY317A, GLY317B, GLY65A, GLY65B, HIS34A, HIS34B, HIS36A, HIS36B, HIS57A, HIS57B, HIS62A, HIS62B, ILE13A, ILE13B, ILE263A, ILE263B, ILE68A, ILE68B, LEU115A, LEU115B, LEU117A, LEU117B, LEU122A, LEU122B, LEU183A, LEU183B, LEU18A, LEU18B, LEU222A, LEU222B, LEU267A, LEU267B, LEU271A, LEU271B, LEU35A, LEU35B, LEU39A, LEU39B, LEU63A, LEU63B, LYS11A, LYS11B, LYS191A, LYS191B, LYS247A, LYS247B, LYS289A, LYS28A, LYS28B, LYS29A, LYS29B, LYS315A, LYS315B, LYS41A, LYS41B, LYS9A, LYS9B, MET224A, MET224B, PHE163A, PHE163B, PHE196A, PHE196B, PHE316A, PHE316B, PHE31A, PHE31B, PHE37A, PHE37B, PHE53A, PHE53B, PRO188A, PRO194A, PRO194B, PRO229A, PRO229B, PRO249B, PRO48A, PRO48B, PRO837A, PRO837B, SER14A, SER14B, SER313B, THR112A, THR112B, THR197A, THR197B, THR228A, THR228B, THR240A, THR240B, THR25B, THR38A, THR38B, THR47A, THR47B, THR58A, THR58B, TRP189A, TRP189B, TRP67A, TRP67B, TYR113A, TYR113B, TYR185A, TYR185B, TYR51A, TYR51B, TYR75A, TYR75B, VAL15A, VAL15B, VAL24A, VAL24B, VAL266A, VAL266B, VAL40A, VAL40B, VAL45A, VAL45B, VAL64A, VAL64B
• A-C: ARG205A, ARG205C, ASP217A, ASP217C, ASP268C, GLN219C, GLN264A, GLN264C, GLU207A, GLU207C, GLU290A, GLU290C, GLY261A, GLY261C, ILE263A, ILE263C, LEU267A, LEU267C, LEU271A, LEU271C, LEU291A, LEU391A, LEU391C, LEU395C, LYS289A, LYS289C, LYS294A, LYS294C, THR394A, THR394C, TYR203A, TYR203C, TYR262A, TYR262C, VAL206A, VAL206C, VAL216A, VAL216C, VAL266C
• A-D: ALA435A, ALA435D, ALA728A, ALA728D, ARG424A, ARG426A, ARG426D, ARG427A, ARG427D, ARG438A, ARG438D, ARG720A, ARG724A, ARG724D, ARG770A, ARG770D, ASN727A, ASN727D, ASN763A, ASN763D, ASP423A, ASP423D, ASP719A, ASP722A, ASP722D, ASP733A, ASP733D, ASP756A, ASP756D, ASP760A, ASP760D, ASP769A, ASP769D, CYS171D, GLN175D, GLN264A, GLN264D, GLN723A, GLN723D, GLN729A, GLN729D, GLN754A, GLN754D, GLU382A, GLU382D, GLU432A, GLU432D, GLU433A, GLU433D, GLU730A, GLU730D, GLY434A, GLY434D, GLY725A, GLY725D, GLY748A, GLY748D, HIS614A, HIS614D, HIS767A, HIS767D, HIS768A, HIS768D, ILE263A, ILE263D, LEU267A, LEU267D, LEU380A, LEU721A, LEU721D, LEU757A, LEU757D, LYS437A, LYS437D, LYS617A, LYS617D, LYS621A, LYS621D, LYS753A, LYS753D, LYS759A, LYS759D, LYS772A, LYS772D, MET176A, MET176D, MET618A, MET618D, MET766A, MET766D, PRO381A, PRO381D, PRO752A, PRO752D, PRO755A, PRO755D, SER747A, SER751A, SER751D, TRP174A, TRP174D, TYR262A, TYR262D, TYR726A, TYR726D, TYR732A, TYR732D, VAL266A, VAL266D, VAL422A, VAL422D, VAL436A, VAL436D
• A-G: ALA415G, ALA416G, ARG43A, ASN44A, GLY420G, PRO419G
• B-C: ALA435B, ALA435C, ALA728B, ALA728C, ARG424B, ARG426B, ARG426C, ARG427B, ARG427C, ARG438B, ARG438C, ARG724B, ARG724C, ARG770B, ARG770C, ASN727B, ASN727C, ASN763B, ASN763C, ASP423B, ASP423C, ASP722B, ASP722C, ASP733B, ASP733C, ASP756B, ASP756C, ASP760B, ASP760C, ASP769B, ASP769C, GLN175B, GLN175C, GLN264B, GLN264C, GLN723B, GLN723C, GLN729B, GLN729C, GLN754B, GLN754C, GLU382B, GLU382C, GLU432B, GLU432C, GLU433B, GLU433C, GLU730B, GLU730C, GLY261B, GLY434B, GLY434C, GLY725B, GLY725C, GLY748B, GLY748C, HIS614B, HIS614C, HIS767B, HIS767C, HIS768B, HIS768C, ILE263B, ILE263C, LEU267B, LEU267C, LEU721B, LEU721C, LEU757B, LEU757C, LYS437C, LYS617B, LYS617C, LYS621B, LYS621C, LYS753B, LYS753C, LYS759B, LYS759C, LYS772B, LYS772C, MET176B, MET176C, MET618B, MET618C, MET766B, MET766C, PRO381B, PRO752B, PRO752C, PRO755B, PRO755C, SER747B, SER747C, SER751B, SER751C, TRP174B, TRP174C, TYR262B, TYR262C, TYR726B, TYR726C, TYR732B, TYR732C, VAL266B, VAL266C, VAL422B, VAL422C, VAL436B, VAL436C
• B-D: ARG205B, ARG205D, ASN270B, ASN270D, ASP217B, ASP217D, ASP268D, GLN264B, GLN264D, GLU207B, GLU207D, GLU290B, GLU290D, GLY261B, GLY261D, HIS390B, HIS390D, ILE263B, ILE263D, LEU267B, LEU267D, LEU271B, LEU271D, LEU391B, LEU391D, LYS289B, LYS289D, LYS294B, LYS294D, THR394B, TYR203B, TYR203D, TYR262B, TYR262D, VAL206B, VAL206D, VAL216B, VAL216D
• B-E: ALA416B, ALA417B, ALA451B, ARG309E, ARG310E, ARG358E, ARG424B, ARG822B, ASN325E, ASN481B, ASP327E, ASP355E, ASP360E, ASP421B, ASP470B, GLN211E, GLN480B, GLN819B, GLU357E, GLU461B, GLU473B, GLU475B, GLU823B, GLY420B, HIS450B, HIS477B, ILE308E, ILE824B, LEU356E, LEU359E, LEU474B, LYS214E, LYS312E, LYS363E, LYS464B, LYS465B, LYS469B, LYS478B, LYS482B, PHE311E, PHE326E, PHE418B, PHE479B, PRO419B, PRO476B, SER210E, SER313E, SER314E, THR209E, TYR472B, TYR75E, VAL354E, VAL452B
• B-F: ALA546F, ALA547F, ARG323B, ARG358B, ARG409B, ARG551F, ARG641F, ASN325B, ASN44F, ASN558F, ASN631F, ASP320B, ASP360B, ASP362B, ASP638F, GLN211B, GLU550F, GLU552F, GLY212B, HIS556F, HIS632F, ILE557F, LEU359B, LEU549F, LYS363B, LYS554F, LYS753F, PRO321B, PRO419B, PRO559F, PRO752F, SER210B, THR209B, THR324B, TRP361B, TYR553F, VAL322B, VAL354B, VAL45F, VAL555F
• B-G: ALA415G, ALA416G, ALA417G, ARG10B, ARG319B, ARG323B, ARG409G, ARG413G, ARG426G, ARG822B, ASN325B, ASN412G, ASP320B, ASP360G, ASP362G, ASP421G, ASP423G, ASP78B, CYS318B, GLN408G, GLN72B, GLN7B, GLN832B, GLU405G, GLU76B, GLU828B, GLU8B, GLY317B, GLY420G, HIS208G, HIS73B, LEU411G, LEU425G, LYS11B, LYS315B, LYS332B, LYS437G, LYS77B, PHE316B, PHE418G, PRO321B, PRO419G, PRO79B, SER210G, SER314B, SER429G, THR209G, TRP361G, TYR74B, TYR75B, VAL322B, VAL414G, VAL422G
• C-D: ALA111C, ALA111D, ALA179C, ALA179D, ALA192C, ALA192D, ALA19C, ALA19D, ALA248C, ALA248D, ALA265C, ALA265D, ALA46C, ALA46D, ALA54C, ALA54D, ARG10C, ARG10D, ARG16C, ARG16D, ARG184C, ARG184D, ARG193C, ARG193D, ARG242D, ARG269C, ARG269D, ARG277C, ARG277D, ARG309C, ARG309D, ARG319D, ARG33C, ARG33D, ARG43C, ARG43D, ARG49C, ARG49D, ARG60C, ARG60D, ARG66C, ARG66D, ARG69C, ARG69D, ASN250C, ASN250D, ASN270C, ASN270D, ASN274C, ASN274D, ASN30C, ASN30D, ASN32C, ASN32D, ASN44C, ASN44D, ASP118C, ASP118D, ASP181C, ASP181D, ASP227C, ASP227D, ASP268C, ASP268D, ASP42C, ASP42D, ASP50C, ASP50D, ASP61C, ASP61D, CYS318D, GLN114C, GLN114D, GLN12C, GLN12D, GLN264C, GLN264D, GLN71C, GLN71D, GLN72C, GLN72D, GLN7D, GLU110C, GLU110D, GLU121C, GLU121D, GLU162C, GLU162D, GLU190C, GLU190D, GLU195C, GLU195D, GLU26C, GLU26D, GLU273C, GLU273D, GLU8D, GLY116C, GLY116D, GLY17C, GLY17D, GLY186C, GLY186D, GLY20C, GLY20D, GLY317D, GLY65C, GLY65D, HIS34C, HIS34D, HIS36C, HIS36D, HIS57C, HIS57D, HIS62C, HIS62D, ILE13C, ILE13D, ILE263C, ILE263D, ILE68C, ILE68D, LEU115C, LEU115D, LEU117C, LEU117D, LEU122C, LEU122D, LEU183C, LEU183D, LEU18C, LEU18D, LEU267C, LEU267D, LEU271C, LEU271D, LEU35C, LEU35D, LEU39C, LEU39D, LEU63C, LEU63D, LYS11C, LYS11D, LYS191C, LYS191D, LYS247C, LYS247D, LYS289D, LYS28C, LYS28D, LYS29C, LYS29D, LYS315D, LYS41C, LYS41D, LYS9C, LYS9D, MET224C, MET224D, PHE163C, PHE163D, PHE196C, PHE196D, PHE316D, PHE31C, PHE31D, PHE37C, PHE37D, PHE53C, PHE53D, PRO188C, PRO188D, PRO194C, PRO194D, PRO229C, PRO229D, PRO249D, PRO48C, PRO48D, PRO837C, PRO837D, SER14C, SER14D, SER313C, SER313D, THR112C, THR112D, THR197C, THR197D, THR228C, THR228D, THR240C, THR240D, THR25C, THR38C, THR38D, THR47C, THR47D, THR58C, THR58D, TRP189C, TRP189D, TRP67C, TRP67D, TYR113C, TYR113D, TYR185C, TYR185D, TYR262C, TYR262D, TYR51C, TYR51D, TYR75C, TYR75D, VAL15C, VAL15D, VAL21D, VAL24C, VAL24D, VAL266C, VAL266D, VAL40C, VAL40D, VAL45C, VAL45D, VAL64C, VAL64D
• E-F: ALA111E, ALA111F, ALA179E, ALA179F, ALA192E, ALA192F, ALA19E, ALA19F, ALA248E, ALA248F, ALA265E, ALA265F, ALA46E, ALA46F, ALA54E, ALA54F, ARG10E, ARG10F, ARG16E, ARG16F, ARG184E, ARG184F, ARG193E, ARG193F, ARG242E, ARG242F, ARG269E, ARG269F, ARG277E, ARG277F, ARG309E, ARG309F, ARG319F, ARG33E, ARG33F, ARG43E, ARG43F, ARG49E, ARG49F, ARG60E, ARG60F, ARG66E, ARG66F, ARG69E, ARG69F, ASN250E, ASN250F, ASN270E, ASN270F, ASN274E, ASN274F, ASN30E, ASN30F, ASN32E, ASN32F, ASN44E, ASN44F, ASP118E, ASP118F, ASP181E, ASP181F, ASP227E, ASP227F, ASP268E, ASP268F, ASP42E, ASP42F, ASP50E, ASP50F, ASP61E, ASP61F, CYS318F, GLN114E, GLN114F, GLN12E, GLN12F, GLN264E, GLN264F, GLN71E, GLN71F, GLN72E, GLN72F, GLU110F, GLU121E, GLU121F, GLU162E, GLU162F, GLU190E, GLU190F, GLU195E, GLU195F, GLU26E, GLU26F, GLU273E, GLU273F, GLU8E, GLU8F, GLY116E, GLY116F, GLY17E, GLY17F, GLY186E, GLY186F, GLY20E, GLY20F, GLY317F, GLY65E, GLY65F, HIS34E, HIS34F, HIS36E, HIS36F, HIS57E, HIS57F, HIS62E, HIS62F, ILE13E, ILE13F, ILE263E, ILE263F, ILE68E, ILE68F, LEU115E, LEU115F, LEU117E, LEU117F, LEU122E, LEU122F, LEU183E, LEU183F, LEU18E, LEU18F, LEU267E, LEU267F, LEU271E, LEU271F, LEU35E, LEU35F, LEU39E, LEU39F, LEU63E, LEU63F, LYS11E, LYS11F, LYS191E, LYS191F, LYS247E, LYS247F, LYS28E, LYS28F, LYS29E, LYS29F, LYS315F, LYS41E, LYS41F, LYS9E, LYS9F, MET224E, MET224F, PHE163E, PHE163F, PHE196E, PHE196F, PHE316F, PHE31E, PHE31F, PHE37E, PHE37F, PHE53E, PHE53F, PRO188E, PRO194E, PRO194F, PRO229E, PRO229F, PRO249F, PRO48E, PRO48F, PRO837E, PRO837F, SER14E, SER14F, SER313E, THR112E, THR112F, THR197E, THR197F, THR228E, THR228F, THR240E, THR240F, THR25E, THR25F, THR38E, THR38F, THR47E, THR47F, THR58E, THR58F, TRP189E, TRP189F, TRP67E, TRP67F, TYR113E, TYR113F, TYR185E, TYR185F, TYR262E, TYR262F, TYR51E, TYR51F, TYR75E, TYR75F, VAL15E, VAL15F, VAL21E, VAL21F, VAL24E, VAL24F, VAL266E, VAL266F, VAL40E, VAL40F, VAL45E, VAL45F, VAL64E, VAL64F
• E-G: ALA265E, ARG205E, ARG205G, ASP217E, ASP217G, ASP268E, ASP268G, GLN219E, GLN219G, GLN264E, GLN264G, GLU207E, GLU207G, GLU290E, GLU290G, GLY261E, GLY261G, ILE263E, ILE263G, LEU267E, LEU267G, LEU271E, LEU271G, LEU291G, LEU391E, LEU391G, LEU395E, LYS289E, LYS289G, LYS294E, LYS294G, THR394E, THR394G, TYR203E, TYR203G, TYR262E, TYR262G, VAL206E, VAL206G, VAL216E, VAL216G, VAL266E
• E-H: ALA435E, ALA435H, ARG386H, ARG424H, ARG426E, ARG426H, ARG427E, ARG427H, ARG438H, ARG724E, ARG724H, ARG770E, ARG770H, ASN763E, ASP423E, ASP423H, ASP722E, ASP722H, ASP733E, ASP733H, ASP756E, ASP756H, ASP760E, ASP760H, CYS171E, GLN175E, GLN175H, GLN264H, GLN723E, GLN729H, GLN754E, GLU382E, GLU382H, GLU432E, GLU432H, GLU433E, GLU433H, GLU730E, GLU730H, GLY172E, GLY173E, GLY261H, GLY434E, GLY434H, GLY748E, HIS614E, HIS767E, HIS767H, HIS768E, HIS768H, ILE263E, ILE263H, LEU267E, LEU267H, LEU757E, LYS437H, LYS617E, LYS621E, LYS753E, LYS753H, LYS759E, LYS759H, MET176E, MET176H, MET618E, PRO381H, PRO752E, PRO755E, SER746E, SER747E, SER751E, TRP174E, TRP174H, TYR262E, TYR262H, VAL266E, VAL266H, VAL422H, VAL431H, VAL436E, VAL436H
• F-G: ALA435F, ALA435G, ALA728F, ALA728G, ARG426F, ARG426G, ARG427F, ARG427G, ARG438F, ARG438G, ARG724F, ARG724G, ARG770F, ARG770G, ASN727F, ASN727G, ASN763F, ASN763G, ASP423F, ASP423G, ASP719G, ASP722F, ASP722G, ASP733F, ASP733G, ASP756F, ASP756G, ASP760F, ASP760G, ASP769F, ASP769G, CYS171F, GLN175F, GLN264F, GLN723F, GLN723G, GLN729F, GLN729G, GLN754F, GLN754G, GLU382F, GLU382G, GLU432F, GLU432G, GLU433F, GLU433G, GLU730F, GLU730G, GLY172F, GLY173F, GLY434F, GLY434G, GLY725F, GLY725G, GLY748F, GLY748G, HIS614F, HIS614G, HIS767F, HIS767G, HIS768F, HIS768G, ILE263F, ILE263G, LEU267F, LEU267G, LEU721F, LEU721G, LEU757F, LEU757G, LYS437F, LYS437G, LYS617F, LYS617G, LYS621F, LYS621G, LYS753F, LYS753G, LYS759F, LYS759G, LYS772F, LYS772G, MET176F, MET176G, MET618F, MET618G, MET766F, MET766G, PRO381F, PRO381G, PRO752F, PRO752G, PRO755F, PRO755G, SER747F, SER747G, SER751F, SER751G, TRP174F, TRP174G, TYR262F, TYR262G, TYR726F, TYR726G, TYR732F, TYR732G, VAL266F, VAL266G, VAL422F, VAL422G, VAL436F, VAL436G
• F-H: ALA265F, ALA265H, ARG205F, ARG205H, ASN270F, ASN270H, ASP217F, ASP217H, ASP268F, ASP268H, GLN219H, GLN264F, GLN264H, GLU207F, GLU207H, GLU290F, GLU290H, GLY261F, GLY261H, HIS390F, HIS390H, ILE263F, ILE263H, LEU267F, LEU267H, LEU271F, LEU271H, LEU291F, LEU291H, LEU391H, LYS289F, LYS289H, LYS294F, LYS294H, THR394F, THR394H, TYR203F, TYR203H, TYR262F, TYR262H, VAL206F, VAL206H, VAL216F, VAL216H
• G-H: ALA111G, ALA111H, ALA179G, ALA179H, ALA192G, ALA192H, ALA19G, ALA19H, ALA248G, ALA248H, ALA265G, ALA265H, ALA46G, ALA46H, ALA54G, ALA54H, ARG10G, ARG10H, ARG16G, ARG16H, ARG184G, ARG184H, ARG193G, ARG193H, ARG242H, ARG269G, ARG269H, ARG277G, ARG277H, ARG309G, ARG309H, ARG319G, ARG319H, ARG33G, ARG33H, ARG43G, ARG43H, ARG49G, ARG49H, ARG60G, ARG60H, ARG66G, ARG66H, ARG69G, ARG69H, ASN250G, ASN250H, ASN270G, ASN270H, ASN274G, ASN274H, ASN30G, ASN30H, ASN32G, ASN32H, ASN44G, ASN44H, ASP118G, ASP118H, ASP181G, ASP181H, ASP227G, ASP227H, ASP268G, ASP268H, ASP42G, ASP42H, ASP50G, ASP50H, ASP61G, ASP61H, ASP6H, CYS318G, CYS318H, GLN114G, GLN114H, GLN12G, GLN12H, GLN264H, GLN71G, GLN71H, GLN72G, GLN72H, GLN7G, GLN7H, GLU110G, GLU110H, GLU121G, GLU121H, GLU162G, GLU162H, GLU190G, GLU190H, GLU195G, GLU195H, GLU26G, GLU26H, GLU273G, GLU273H, GLU8G, GLU8H, GLY116G, GLY116H, GLY17G, GLY17H, GLY186G, GLY186H, GLY20G, GLY20H, GLY317G, GLY317H, GLY65G, GLY65H, HIS34G, HIS34H, HIS36G, HIS36H, HIS57G, HIS57H, HIS62G, HIS62H, ILE13G, ILE13H, ILE263G, ILE263H, ILE68G, ILE68H, LEU115G, LEU115H, LEU117G, LEU117H, LEU122G, LEU122H, LEU183G, LEU183H, LEU18G, LEU18H, LEU267G, LEU267H, LEU271G, LEU271H, LEU35G, LEU35H, LEU39G, LEU39H, LEU63G, LEU63H, LYS11G, LYS11H, LYS191G, LYS191H, LYS247G, LYS247H, LYS289H, LYS28G, LYS28H, LYS29G, LYS29H, LYS315G, LYS315H, LYS41G, LYS41H, LYS9G, LYS9H, MET224G, MET224H, PHE163G, PHE163H, PHE196G, PHE196H, PHE316G, PHE316H, PHE31G, PHE31H, PHE37G, PHE37H, PHE53G, PHE53H, PRO194G, PRO194H, PRO229G, PRO229H, PRO249G, PRO249H, PRO48G, PRO48H, PRO837G, SER14G, SER14H, THR112G, THR112H, THR197G, THR197H, THR228G, THR228H, THR240G, THR240H, THR25H, THR38G, THR38H, THR47G, THR47H, THR58G, THR58H, TRP189G, TRP189H, TRP67G, TRP67H, TYR113G, TYR113H, TYR185G, TYR185H, TYR262G, TYR51G, TYR51H, TYR75G, TYR75H, VAL15G, VAL15H, VAL21G, VAL21H, VAL24G, VAL24H, VAL266G, VAL266H, VAL40G, VAL40H, VAL45G, VAL45H, VAL64G, VAL64H