3E37

protein farnesyltransferase complexed with bisubstrate ethylenediamine scaffold inhibitor 5

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 299
  • Norm. En. per Res.: -4.3166
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-167.7786	-110.4066	-1012.49	-1290.6752	299	31	16	36525	11	101	113

Interface residues

• A-B: ALA100B, ALA125B, ALA128A, ALA129A, ALA153B, ALA197A, ALA202A, ALA249B, ALA276A, ALA313A, ALA324B, ALA336B, ALA345A, ALA94B, ARG102B, ARG104A, ARG137A, ARG138A, ARG173A, ARG204B, ARG206A, ARG232A, ARG233B, ARG240A, ARG282B, ARG285B, ARG293B, ARG29B, ARG34B, ARG352A, ARG357A, ARG361A, ARG86B, ARG89B, ARG97A, ASN127A, ASN130A, ASN165A, ASN199A, ASN233A, ASN234A, ASN236B, ASN238A, ASN246A, ASN271B, ASN273A, ASN278A, ASN295B, ASN81A, ASN85A, ASP110A, ASP127B, ASP196A, ASP202B, ASP230A, ASP286A, ASP317A, ASP321A, ASP322B, ASP349A, ASP39B, ASP40B, ASP82A, ASP93B, ASP94A, ASP99B, CYS106B, CYS129B, CYS135B, CYS234B, CYS294B, CYS97B, GLN108A, GLN130B, GLN148B, GLN162A, GLN167A, GLN195A, GLN204A, GLN207A, GLN211A, GLN235B, GLN239A, GLN277B, GLN283B, GLN285A, GLN291B, GLN334B, GLN335B, GLN364A, GLN38B, GLN50B, GLN80A, GLN89A, GLN90B, GLU200B, GLU229A, GLU238B, GLU248B, GLU274A, GLU287B, GLU31B, GLU320A, GLU324A, GLU347A, GLU354A, GLU35B, GLU43B, GLU49B, GLU96B, GLY143B, GLY144B, GLY145B, GLY147B, GLY198B, GLY199B, GLY239B, GLY242B, GLY243B, GLY246B, GLY251B, GLY282A, GLY288A, GLY288B, GLY289B, GLY292B, GLY321B, GLY360A, GLY83A, GLY87B, HIS135A, HIS151B, HIS170A, HIS171A, HIS196B, HIS201A, HIS205A, HIS250B, HIS272A, HIS306A, HIS314B, HIS329B, HIS32B, HIS333B, ILE109B, ILE123B, ILE165B, ILE241B, ILE267A, ILE283A, ILE351A, ILE359A, ILE48B, ILE90A, ILE91A, LEU105B, LEU107A, LEU110B, LEU126A, LEU132B, LEU134B, LEU152B, LEU194B, LEU227A, LEU269A, LEU272B, LEU275B, LEU276B, LEU280A, LEU284A, LEU289A, LEU297B, LEU310B, LEU313B, LEU317B, LEU325B, LEU337B, LEU344A, LEU363A, LEU37B, LEU84B, LEU88B, LEU91B, LEU98B, LYS164A, LYS198A, LYS228A, LYS268A, LYS273B, LYS281A, LYS296B, LYS346A, LYS348A, LYS353A, LYS366A, LYS95A, MET195B, MET247B, MET266A, MET284B, MET327B, MET331B, PHE103A, PHE131B, PHE136A, PHE142B, PHE242A, PHE286B, PHE290B, PHE314A, PHE332B, PHE362B, PHE96A, PRO103B, PRO146B, PRO150B, PRO154B, PRO245B, PRO271A, PRO309A, PRO323B, PRO79A, PRO84A, PRO86A, SER101B, SER235A, SER245A, SER274B, SER275A, SER27B, SER281B, SER308A, SER326B, SER328B, SER362A, SER365A, SER41B, SER47B, SER93A, THR126B, THR132A, THR155B, THR254B, THR280B, THR350A, THR44B, THR46B, THR92B, TRP104B, TRP108B, TRP134A, TRP169A, TRP203A, TRP208A, TRP216A, TRP230B, TRP237A, TRP237B, TRP277A, TRP278B, TRP330B, TRP356A, TYR100A, TYR107B, TYR131A, TYR149B, TYR166A, TYR182B, TYR200A, TYR241A, TYR250A, TYR253B, TYR26B, TYR279A, TYR310A, TYR340B, TYR355A, TYR358A, TYR92A, TYR95B, VAL124B, VAL128B, VAL133A, VAL139A, VAL174A, VAL197B, VAL201B, VAL203B, VAL231A, VAL236A, VAL244B, VAL270A, VAL279B, VAL316A, VAL42B, VAL45B, VAL78A, VAL87A, VAL88A