3DZY

intact ppar gamma - rxr alpha nuclear receptor complex on dna bound with rosiglitazone, 9-cis retinoic acid and ncoa2 peptide

• Total interactions analyzed: 15
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-G
  • Int. Res.: 41
  • Norm. En. per Res.: -3.5299
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-D	-31.13	-88.4284	-371.449	-491.0074	208	45	10	18807	4	99	101
A-G	-11.6024	-20.4552	-112.668	-144.7256	41	14	8	5257	1	14	6
D-E	-10.2811	-13.2513	-114.523	-138.0553	47	8	5	5880	0	10	10

Interface residues

• A-D: ALA197A, ALA204A, ALA233D, ALA235D, ALA303A, ALA344A, ALA391A, ALA398A, ALA402A, ALA416A, ALA424A, ALA433D, ARG137D, ARG153D, ARG159D, ARG166D, ARG202A, ARG209A, ARG211A, ARG234D, ARG348A, ARG350D, ARG393A, ARG397D, ARG414A, ARG421A, ARG426A, ARG443D, ASN151D, ASN160D, ASN216A, ASN218A, ASN335D, ASN375D, ASN377A, ASN412D, ASP149D, ASP166A, ASP214A, ASP243D, ASP251D, ASP337D, ASP359A, ASP379A, ASP396D, ASP411D, ASP441D, CYS148D, CYS152D, CYS162D, CYS165D, CYS171A, CYS190A, CYS195A, GLN163D, GLN193A, GLN206A, GLN210A, GLN410D, GLN411A, GLN415D, GLN430D, GLN437D, GLN444D, GLN451D, GLN454D, GLU203A, GLU207A, GLU208A, GLU217A, GLU219A, GLU307A, GLU324D, GLU351D, GLU352A, GLU369D, GLU390A, GLU394A, GLU401A, GLU407D, GLU418D, GLU427D, GLU434A, GLU448D, GLY148A, GLY199A, GLY212A, GLY239D, GLY338D, GLY395D, GLY399D, GLY413A, GLY429A, HIS155D, HIS435A, HIS449D, ILE154D, ILE236D, ILE249D, ILE345A, ILE373A, ILE391D, ILE428A, ILE445D, LEU150D, LEU167A, LEU196A, LEU237D, LEU340D, LEU353A, LEU377D, LEU393D, LEU400A, LEU400D, LEU414D, LEU417D, LEU418A, LEU419A, LEU420A, LEU422A, LEU425A, LEU430A, LEU431D, LEU433A, LEU435D, LEU436D, LEU442D, LEU476D, LYS145A, LYS157D, LYS161D, LYS175A, LYS194A, LYS201A, LYS213A, LYS240D, LYS244D, LYS336D, LYS354D, LYS356A, LYS373D, LYS381A, LYS395A, LYS404D, LYS405A, LYS417A, LYS431A, LYS434D, LYS438D, MET198A, MET200A, MET334D, MET348D, MET360A, MET439D, PHE159A, PHE247D, PHE347D, PHE352D, PHE370D, PHE387D, PHE415A, PHE432D, PHE437A, PRO246D, PRO378A, PRO386A, PRO398D, PRO412A, PRO423A, SER158D, SER245D, SER254D, SER355D, SER380A, SER394D, SER399A, SER427A, SER428D, SER429D, THR162A, THR168A, THR170A, THR238D, THR241D, THR349D, THR351A, THR440D, THR447D, TYR147A, TYR169A, TYR189A, TYR192A, TYR250D, TYR320D, TYR397A, TYR477D, VAL149A, VAL163A, VAL205A, VAL248D, VAL372D, VAL374A, VAL390D, VAL396A, VAL403D, VAL446D, VAL450D
• A-G: ALA283A, ALA303A, ARG302A, ARG692G, ASP273A, ASP295A, ASP296A, ASP448A, ASP696G, GLN297A, GLN695G, GLU281A, GLU453A, GLY304A, HIS691G, ILE299A, ILE689G, LEU276A, LEU279A, LEU292A, LEU294A, LEU300A, LEU301A, LEU451A, LEU690G, LEU693G, LEU694G, LYS284A, LYS688G, MET452A, MET454A, PHE277A, PHE289A, PHE450A, PRO293A, SER290A, THR278A, THR449A, TRP305A, VAL280A, VAL298A
• D-E: ALA300D, ARG692E, ASN312D, ASP310D, ASP313D, ASP475D, ASP696E, GLN294D, GLN314D, GLN470D, GLN695E, GLU291D, GLU295D, GLU298D, GLU471D, GLY321D, HIS466D, HIS691E, ILE296D, ILE392D, ILE472D, ILE689E, LEU309D, LEU311D, LEU317D, LEU318D, LEU468D, LEU469D, LEU690E, LEU693E, LEU694E, LYS301D, LYS319D, LYS474D, LYS688E, PHE306D, PRO467D, SER697E, THR297D, THR316D, TYR320D, TYR473D, VAL290D, VAL293D, VAL307D, VAL315D, VAL322D