3DWL

crystal structure of fission yeast arp2/3 complex lacking the arp2 subunit

• Total interactions analyzed: 66
• Total true interactions: 22
• Strongest Interaction:
  • Chains: A-D
  • Int. Res.: 134
  • Norm. En. per Res.: -3.8548
• Hub Node: C(6)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-D	-56.9599	-123.8877	-335.698	-516.5457	134	22	7	13948	10	84	60
A-E	0.0	0.0	-61.3232	-61.3232	56	1	5	3327	0	17	9
A-F	-2.2794	-31.2692	-21.8876	-55.4362	28	4	0	1000	3	13	6
A-H	-3.5541	0.0	-106.178	-109.7321	99	8	1	5133	0	28	29
C-D	0.0	0.0	-1.0119	-1.0119	14	0	0	167	0	8	4
C-F	-15.2307	-4.0642	-196.147	-215.4419	104	9	5	8682	0	39	30
C-G	-6.3056	-9.5688	-74.5711	-90.4455	41	6	2	3223	0	7	9
C-B	-2.93	0.0	-106.794	-109.724	99	8	0	5174	0	29	28
C-I	0.0	0.0	-21.8256	-21.8256	23	0	0	1270	0	4	4
C-J	0.0	0.0	-8.4854	-8.4854	14	1	0	430	0	8	1
D-F	-25.8218	-95.1899	-477.685	-598.6967	161	18	22	19774	6	59	58
D-H	0.0	0.0	-30.8693	-30.8693	24	1	0	1523	0	4	4
E-H	0.0	0.0	-7.4624	-7.4624	13	0	0	393	0	7	1
F-G	-13.9326	0.0	-174.089	-188.0216	78	12	11	8464	0	7	8
B-I	-50.8212	-106.2541	-350.667	-507.7423	134	24	7	14260	8	85	63
B-J	0.0	0.0	-65.4251	-65.4251	57	2	6	3414	0	17	9
B-K	0.0	-29.9178	-21.4061	-51.3239	30	2	0	1065	3	15	8
H-I	0.0	0.0	-0.8603	-0.8603	14	0	0	149	0	7	4
H-K	-14.4329	-3.957	-198.682	-217.072	104	10	5	8787	0	39	29
H-L	-6.7325	-9.5589	-77.6385	-93.9299	41	7	2	3288	0	7	9
I-K	-25.7702	-97.5817	-456.778	-580.1299	156	16	22	19535	6	60	57
K-L	-17.2852	0.0	-165.15	-182.4352	77	6	11	8161	0	7	8

Interface residues

• A-D: ALA143A, ALA22A, ALA26A, ALA275D, ALA278D, ALA289D, ARG107A, ARG116D, ARG118A, ARG162D, ARG185D, ARG266D, ARG283D, ARG285D, ASN101A, ASN141A, ASN151A, ASN24A, ASN267D, ASN5A, ASN78A, ASN7D, ASN8D, ASP103A, ASP123A, ASP163D, ASP189D, ASP25A, ASP33D, ASP35D, ASP5D, ASP71A, ASP73A, ASP79A, CYS119A, CYS152A, GLN110A, GLN111A, GLN282D, GLN29D, GLN395A, GLU106A, GLU120A, GLU122A, GLU13D, GLU140A, GLU144A, GLU148A, GLU165D, GLU186D, GLU187D, GLU410A, GLU70A, GLY20A, GLY23A, GLY36D, HIS104A, HIS124A, HIS270D, HIS272D, HIS281D, HIS40D, ILE11D, ILE145A, ILE273D, ILE41D, ILE76A, ILE8A, ILE99A, ILE9D, LEU113A, LEU117A, LEU14D, LEU19A, LEU2D, LEU4D, LEU72A, LYS115A, LYS115D, LYS183D, LYS274D, LYS277D, LYS286D, LYS406A, MET105A, MET113D, MET146A, MET1D, MET280D, MET284D, PHE10D, PHE114A, PHE126A, PHE147A, PHE150A, PHE184D, PHE196D, PHE271D, PHE31A, PHE34D, PHE39D, PHE74A, PHE75A, PRO121A, PRO27A, PRO7A, SER112A, SER112D, SER149A, SER276D, SER28A, SER3D, THR188D, THR268D, THR32D, THR38D, THR69A, TRP102A, TRP387A, TYR116A, TYR12D, TYR161D, TYR21A, TYR279D, TYR29A, TYR409A, TYR6D, VAL264D, VAL288D, VAL30A, VAL30D, VAL31D, VAL37D, VAL6A
• A-E: ALA299A, ALA53E, ARG167E, ARG225A, ARG286A, ARG52E, ARG58E, ASN171E, ASN295A, ASN54E, ASN59E, ASP250A, ASP259A, ASP281A, CYS163E, CYS47E, CYS55E, GLN221A, GLU285A, GLU291A, GLU297A, GLU46E, GLY283A, GLY49E, ILE251A, ILE280A, ILE292A, ILE298A, LEU223A, LEU224A, LEU266A, LEU288A, LEU304A, LEU50E, LYS159E, LYS166E, LYS253A, LYS267A, PHE164E, PHE219A, PHE255A, PHE258A, PHE284A, PHE287A, PHE51E, PHE56E, PHE57E, SER222A, SER256A, SER301A, THR162E, TRP160E, TRP161E, TYR268A, VAL252A, VAL282A
• A-F: ALA414A, ARG156F, ARG418A, ARG97F, ASN141A, ASP71A, ASP73A, GLN110A, GLU137A, GLU140A, GLU144A, GLU148A, GLU70A, GLU99F, GLY155F, GLY413A, GLY96F, LEU159F, LEU72A, LYS89F, PHE152F, PHE93F, SER100F, SER149A, THR69A, TRP102A, TYR409A, VAL160F
• A-H: ALA26A, ALA292H, ALA299A, ALA2H, ALA354H, ALA362H, ALA80A, ALA84A, ALA86A, ARG214A, ARG225A, ARG23H, ARG309H, ARG381A, ARG383A, ARG38A, ASN24A, ASN304H, ASN384A, ASN43H, ASN78A, ASP188A, ASP215A, ASP25A, ASP291H, ASP79A, GLN221A, GLN22H, GLN5H, GLU238A, GLU242A, GLU307H, GLU310H, GLU311H, GLY15A, GLY293H, GLY303H, GLY306H, GLY308H, GLY335A, GLY42H, GLY77A, GLY87A, HIS301H, ILE280A, LEU19A, LEU234A, LEU338A, LEU339H, LEU374H, LEU377H, LEU7H, LEU81A, LYS18A, LYS235A, LYS296H, LYS82A, LYS83A, PHE219A, PHE31A, PRO27A, PRO32A, PRO340H, SER17A, SER222A, SER28A, SER295H, SER298H, SER300A, SER301A, SER337H, SER338H, SER4H, SER85A, SER89A, THR14A, THR217A, THR236A, THR24H, THR294H, THR297H, THR300H, THR302H, THR305H, THR33A, THR356H, THR361H, THR376H, THR3H, TRP387A, TYR16A, TYR218A, TYR29A, TYR353H, TYR88A, TYR92A, VAL30A, VAL34A, VAL6H
• C-D: ASN345C, ASP301D, ASP369C, GLN344C, GLU303D, GLY370C, ILE9C, LEU10C, LYS12C, PRO11C, PRO13C, PRO300D, THR368C, VAL302D
• C-F: ALA102C, ALA103C, ALA121C, ALA166C, ALA18F, ALA21F, ALA31C, ARG101C, ARG122C, ARG146C, ARG168C, ARG255C, ARG32F, ARG371C, ARG42F, ARG77C, ASN100C, ASN120F, ASN271C, ASN345C, ASN68F, ASP133F, ASP167C, ASP226C, ASP369C, ASP55C, ASP76C, CYS165C, GLN33F, GLN344C, GLN75C, GLU124F, GLU125F, GLU23F, GLU24F, GLU28F, GLU31F, GLU45F, GLY120C, GLY206C, GLY269C, GLY370C, HIS122F, HIS129F, HIS209C, HIS225C, HIS343C, ILE149C, ILE29F, ILE347C, ILE46F, ILE57C, LEU127F, LEU150C, LEU20F, LEU22F, LEU252C, LEU339C, LEU47F, LEU48F, LYS128F, LYS12C, LYS130F, LYS49F, LYS56C, MET126F, MET346C, PHE25F, PRO13C, PRO253C, PRO340C, PRO44F, SER119C, SER147C, SER14C, SER19F, SER227C, SER26F, SER273C, SER27F, SER337C, SER338C, SER34F, SER43F, SER65F, SER66F, SER69F, SER74C, THR104C, THR123F, THR148C, THR17F, THR32C, THR341C, THR368C, THR59C, TRP207C, TYR121F, TYR15C, TYR270C, TYR272C, VAL30F, VAL58C, VAL67F
• C-G: ARG144G, ARG149G, ARG168C, ASN147G, ASN271C, ASP105G, ASP167C, ASP226C, CYS141G, GLN251C, GLU102G, GLY138G, GLY140G, GLY205C, GLY206C, GLY224C, HIS209C, HIS225C, ILE104G, ILE136G, ILE139G, ILE142G, LEU146G, LEU249C, LEU252C, LEU254C, LYS248C, PRO253C, SER137G, SER148G, SER227C, SER228C, SER250C, THR101G, TRP207C, TYR270C, VAL134G, VAL143G, VAL145G, VAL229C, VAL247C
• C-B: ALA26B, ALA292C, ALA299B, ALA2C, ALA362C, ALA80B, ALA84B, ALA86B, ARG214B, ARG225B, ARG23C, ARG309C, ARG381B, ARG383B, ARG38B, ASN24B, ASN304C, ASN384B, ASN43C, ASN78B, ASP188B, ASP215B, ASP25B, ASP291C, ASP79B, GLN221B, GLN22C, GLN5C, GLU238B, GLU242B, GLU307C, GLU310C, GLU311C, GLY15B, GLY293C, GLY303C, GLY306C, GLY308C, GLY335B, GLY42C, GLY77B, GLY87B, HIS301C, ILE280B, LEU19B, LEU234B, LEU338B, LEU339C, LEU374C, LEU377C, LEU7C, LEU81B, LYS18B, LYS235B, LYS296C, LYS82B, LYS83B, PHE219B, PHE31B, PRO27B, PRO32B, PRO340C, SER17B, SER222B, SER28B, SER295C, SER298C, SER300B, SER301B, SER337C, SER338C, SER4C, SER85B, SER89B, THR14B, THR217B, THR236B, THR24C, THR294C, THR297C, THR300C, THR302C, THR305C, THR33B, THR356C, THR361C, THR376C, THR3C, TRP387B, TYR16B, TYR218B, TYR29B, TYR353C, TYR88B, TYR92B, VAL220B, VAL30B, VAL34B, VAL6C
• C-I: ARG18I, ASN23I, ASN304C, GLN29I, GLU13I, GLU17I, GLU22I, GLY303C, ILE11I, ILE9I, LEU14I, LEU15I, LYS296C, PHE10I, PHE299C, SER20I, SER21I, SER298C, THR16I, THR297C, THR300C, THR302C, THR305C
• C-J: ARG23C, ASN20C, ASP41C, GLN22C, GLN40C, GLU25C, GLU39C, GLY42C, GLY44C, LYS166J, SER165J, THR162J, THR24C, TRP45C
• D-F: ALA144F, ALA157F, ALA161F, ALA203D, ALA212D, ALA275D, ALA278D, ALA289D, ALA298D, ALA98F, ARG156F, ARG158F, ARG190D, ARG204D, ARG205D, ARG248D, ARG255D, ARG266D, ARG283D, ARG285D, ARG287D, ARG297D, ARG84F, ARG88F, ARG97F, ASN154F, ASN254D, ASN267D, ASN296D, ASP133F, ASP143F, ASP189D, ASP202D, ASP257D, ASP290D, ASP301D, ASP80F, CYS167F, CYS258D, GLN198D, GLN214D, GLN263D, GLN282D, GLN292D, GLN92F, GLU124F, GLU125F, GLU137F, GLU140F, GLU141F, GLU145F, GLU148F, GLU162F, GLU186D, GLU187D, GLU199D, GLU81F, GLU83F, GLU99F, GLY155F, GLY193D, GLY96F, HIS122F, HIS129F, HIS249D, HIS261D, HIS270D, HIS272D, HIS281D, ILE103F, ILE118F, ILE135F, ILE146F, ILE191D, ILE259D, ILE262D, ILE273D, ILE82F, ILE85F, LEU104F, LEU127F, LEU131F, LEU151F, LEU153F, LEU159F, LEU165F, LEU197D, LEU216D, LEU245D, LEU269D, LEU295D, LEU2D, LEU4D, LEU86F, LEU94F, LYS128F, LYS130F, LYS150F, LYS194D, LYS277D, LYS286D, LYS293D, LYS299D, LYS89F, MET126F, MET139F, MET149F, MET1D, MET280D, MET284D, MET91F, MET95F, PHE101F, PHE102F, PHE116F, PHE123D, PHE127D, PHE134F, PHE138F, PHE152F, PHE168F, PHE180D, PHE192D, PHE196D, PHE200D, PHE243D, PHE246D, PHE250D, PHE265D, PHE271D, PHE291D, PHE90F, PHE93F, PRO213D, PRO300D, SER100F, SER147F, SER166F, SER260D, SER276D, SER3D, THR163F, THR188D, THR211D, THR268D, TYR164F, TYR219D, TYR279D, VAL132F, VAL142F, VAL160F, VAL178D, VAL195D, VAL201D, VAL215D, VAL241D, VAL244D, VAL264D, VAL288D, VAL294D, VAL87F
• D-H: ARG18D, ASN23D, ASN304H, GLN29D, GLU13D, GLU17D, GLU22D, GLY303H, ILE11D, ILE9D, LEU14D, LEU15D, LYS296H, PHE10D, PHE299H, SER20D, SER21D, SER298H, THR16D, THR297H, THR300H, THR302H, THR305H, TYR12D
• E-H: ARG23H, ASN20H, ASP41H, GLN22H, GLN40H, GLU25H, GLU39H, GLY42H, LYS166E, SER165E, THR162E, THR24H, TRP45H
• F-G: ALA116G, ALA11F, ALA18F, ALA21F, ARG113G, ARG13F, ARG144G, ARG149G, ARG55F, ARG6F, ARG73G, ASN106G, ASN109G, ASN10F, ASN117G, ASN122G, ASN128G, ASN147G, ASN3F, ASN56F, ASP105G, CYS141G, CYS61F, GLN60F, GLU131G, GLU135G, GLU45F, GLU57F, GLU64F, GLY114G, GLY138G, GLY140G, GLY66G, HIS130G, ILE111G, ILE139G, ILE142G, ILE63F, LEU115G, LEU126G, LEU127G, LEU146G, LEU16F, LEU20F, LEU47F, LEU48F, LEU51F, LEU5F, LEU62F, LEU9F, LYS49F, PHE110G, PRO44F, PRO50F, PRO7F, SER123G, SER124G, SER148G, SER14F, SER19F, SER54F, SER65F, SER66F, THR15F, THR17F, THR4F, TRP129G, TYR112F, TYR112G, TYR8F, VAL108G, VAL12F, VAL134G, VAL143G, VAL145G, VAL52F, VAL53F, VAL70F
• B-I: ALA143B, ALA22B, ALA26B, ALA275I, ALA278I, ALA289I, ARG107B, ARG116I, ARG118B, ARG162I, ARG185I, ARG266I, ARG283I, ARG285I, ASN101B, ASN141B, ASN151B, ASN24B, ASN267I, ASN5B, ASN78B, ASN7I, ASN8I, ASP103B, ASP123B, ASP163I, ASP189I, ASP25B, ASP33I, ASP35I, ASP5I, ASP71B, ASP73B, ASP79B, CYS119B, CYS152B, GLN110B, GLN111B, GLN282I, GLN29I, GLN395B, GLU106B, GLU120B, GLU122B, GLU13I, GLU140B, GLU144B, GLU148B, GLU165I, GLU186I, GLU187I, GLU410B, GLU70B, GLY20B, GLY23B, GLY36I, HIS104B, HIS124B, HIS270I, HIS272I, HIS281I, HIS40I, ILE11I, ILE145B, ILE273I, ILE41I, ILE76B, ILE8B, ILE99B, ILE9I, LEU113B, LEU117B, LEU14I, LEU19B, LEU2I, LEU4I, LEU72B, LYS115B, LYS115I, LYS183I, LYS274I, LYS277I, LYS286I, LYS406B, MET105B, MET113I, MET146B, MET1I, MET280I, MET284I, PHE10I, PHE114B, PHE126B, PHE147B, PHE150B, PHE184I, PHE196I, PHE271I, PHE34I, PHE39I, PHE74B, PHE75B, PRO121B, PRO27B, PRO7B, SER112B, SER112I, SER149B, SER276I, SER28B, SER3I, THR188I, THR268I, THR32I, THR38I, THR69B, TRP102B, TRP387B, TYR116B, TYR12I, TYR161I, TYR21B, TYR279I, TYR29B, TYR409B, TYR6I, TYR86I, VAL264I, VAL288I, VAL30B, VAL30I, VAL31I, VAL37I, VAL6B
• B-J: ALA299B, ALA53J, ARG167J, ARG225B, ARG286B, ARG52J, ARG58J, ASN171J, ASN295B, ASN54J, ASN59J, ASP250B, ASP259B, ASP281B, CYS163J, CYS47J, CYS55J, GLN221B, GLU285B, GLU291B, GLU297B, GLU46J, GLY283B, GLY49J, ILE251B, ILE280B, ILE292B, ILE298B, LEU223B, LEU224B, LEU266B, LEU288B, LEU304B, LEU50J, LYS159J, LYS166J, LYS253B, LYS267B, PHE164J, PHE219B, PHE255B, PHE258B, PHE284B, PHE287B, PHE51J, PHE56J, PHE57J, SER222B, SER256B, SER301B, THR162J, TRP160J, TRP161J, TYR268B, VAL220B, VAL252B, VAL282B
• B-K: ALA414B, ARG156K, ARG418B, ARG97K, ASN141B, ASP71B, ASP73B, GLN110B, GLN92K, GLU137B, GLU140B, GLU144B, GLU148B, GLU410B, GLU70B, GLU99K, GLY155K, GLY413B, GLY96K, LEU159K, LEU72B, LYS89K, PHE93K, SER100K, SER149B, SER415B, THR69B, TRP102B, TYR409B, VAL160K
• H-I: ASN345H, ASP301I, ASP369H, GLN344H, GLU303I, GLY370H, ILE9H, LEU10H, LYS12H, PRO11H, PRO13H, PRO300I, THR368H, VAL302I
• H-K: ALA102H, ALA103H, ALA121H, ALA166H, ALA18K, ALA21K, ALA31H, ARG101H, ARG122H, ARG146H, ARG168H, ARG255H, ARG32K, ARG371H, ARG42K, ARG77H, ASN100H, ASN120K, ASN271H, ASN345H, ASN68K, ASP133K, ASP167H, ASP226H, ASP369H, ASP55H, ASP76H, CYS165H, GLN33K, GLN344H, GLN75H, GLU124K, GLU125K, GLU23K, GLU24K, GLU28K, GLU31K, GLU45K, GLY120H, GLY206H, GLY269H, GLY370H, HIS122K, HIS129K, HIS209H, HIS225H, HIS343H, ILE149H, ILE29K, ILE347H, ILE46K, ILE57H, LEU127K, LEU150H, LEU20K, LEU22K, LEU252H, LEU339H, LEU47K, LEU48K, LYS128K, LYS12H, LYS130K, LYS49K, LYS56H, MET126K, MET346H, PHE25K, PRO13H, PRO253H, PRO340H, PRO44K, SER119H, SER147H, SER14H, SER19K, SER227H, SER26K, SER273H, SER27K, SER337H, SER338H, SER34K, SER43K, SER65K, SER66K, SER69K, SER74H, THR104H, THR123K, THR148H, THR17K, THR32H, THR341H, THR368H, THR59H, TRP207H, TYR121K, TYR15H, TYR270H, TYR272H, VAL30K, VAL58H, VAL67K
• H-L: ARG144L, ARG149L, ARG168H, ASN147L, ASN271H, ASP105L, ASP167H, ASP226H, CYS141L, GLN251H, GLU102L, GLY138L, GLY140L, GLY205H, GLY206H, GLY224H, HIS209H, HIS225H, ILE104L, ILE136L, ILE139L, ILE142L, LEU146L, LEU249H, LEU252H, LEU254H, LYS248H, PRO253H, SER137L, SER148L, SER227H, SER228H, SER250H, THR101L, TRP207H, TYR270H, VAL134L, VAL143L, VAL145L, VAL229H, VAL247H
• I-K: ALA144K, ALA157K, ALA161K, ALA203I, ALA212I, ALA275I, ALA278I, ALA289I, ALA298I, ALA98K, ARG156K, ARG158K, ARG190I, ARG204I, ARG205I, ARG248I, ARG255I, ARG266I, ARG283I, ARG285I, ARG287I, ARG297I, ARG84K, ARG88K, ARG97K, ASN154K, ASN254I, ASN267I, ASN296I, ASP133K, ASP143K, ASP189I, ASP202I, ASP257I, ASP290I, ASP301I, ASP80K, CYS167K, CYS258I, GLN198I, GLN214I, GLN263I, GLN282I, GLN292I, GLN92K, GLU124K, GLU125K, GLU137K, GLU140K, GLU141K, GLU145K, GLU148K, GLU162K, GLU186I, GLU187I, GLU199I, GLU81K, GLU83K, GLU99K, GLY155K, GLY193I, GLY96K, HIS122K, HIS129K, HIS249I, HIS261I, HIS272I, HIS281I, ILE103K, ILE118K, ILE135K, ILE146K, ILE191I, ILE259I, ILE262I, ILE273I, ILE82K, ILE85K, LEU104K, LEU127K, LEU131K, LEU151K, LEU153K, LEU159K, LEU165K, LEU197I, LEU245I, LEU269I, LEU295I, LEU2I, LEU4I, LEU86K, LEU94K, LYS128K, LYS130K, LYS150K, LYS194I, LYS277I, LYS286I, LYS293I, LYS299I, LYS89K, MET126K, MET139K, MET149K, MET1I, MET280I, MET284I, MET91K, MET95K, PHE101K, PHE102K, PHE116K, PHE127I, PHE134K, PHE138K, PHE152K, PHE168K, PHE180I, PHE192I, PHE196I, PHE200I, PHE243I, PHE246I, PHE250I, PHE265I, PHE271I, PHE291I, PHE90K, PHE93K, PRO213I, PRO300I, SER100K, SER147K, SER166K, SER260I, SER276I, SER3I, THR163K, THR188I, THR211I, THR268I, TYR164K, TYR219I, TYR279I, VAL132K, VAL142K, VAL160K, VAL178I, VAL195I, VAL201I, VAL215I, VAL264I, VAL288I, VAL294I, VAL87K
• K-L: ALA116L, ALA11K, ALA18K, ALA21K, ARG113L, ARG13K, ARG144L, ARG149L, ARG55K, ARG6K, ARG73L, ASN109L, ASN10K, ASN117L, ASN122L, ASN128L, ASN147L, ASN3K, ASN56K, ASP105L, CYS141L, CYS61K, GLN60K, GLU131L, GLU135L, GLU45K, GLU57K, GLU64K, GLY114L, GLY138L, GLY140L, HIS130L, ILE111L, ILE139L, ILE142L, ILE63K, LEU115L, LEU126L, LEU127L, LEU146L, LEU16K, LEU20K, LEU47K, LEU48K, LEU51K, LEU5K, LEU62K, LEU9K, LYS49K, PHE110L, PRO44K, PRO50K, PRO7K, SER123L, SER124L, SER148L, SER14K, SER19K, SER54K, SER65K, SER66K, THR15K, THR17K, THR4K, TRP129L, TYR112K, TYR112L, TYR8K, VAL108L, VAL125L, VAL12K, VAL134L, VAL143L, VAL145L, VAL52K, VAL53K, VAL70K