3DUH

structure of interleukin-23

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 135
  • Norm. En. per Res.: -1.8259
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-47.368	-16.8159	-182.306	-246.4899	135	7	4	7475	0	32	32
A-C	-30.2599	-48.2202	390.095	311.6149	88	15	6	9328	4	18	14
A-D	0.0	-1.1284	-22.493	-23.6214	28	1	0	903	0	7	7
B-C	0.0	-1.1047	-22.1153	-23.22	23	1	0	907	0	7	7
B-D	-32.8911	-36.4376	418.888	349.5593	90	12	6	9702	4	19	14

Interface residues

• A-B: ALA150A, ALA150B, ALA151A, ALA151B, ALA176A, ALA176B, ALA179A, ALA179B, ALA180A, ALA180B, ARG117A, ARG117B, ASN113A, ASN113B, ASP129A, ASP129B, ASP174A, ASP174B, ASP238A, ASP238B, ASP41A, ASP41B, ASP7A, ASP7B, CYS148A, CYS148B, CYS177A, CYS177B, CYS68A, CYS68B, GLN144A, GLN144B, GLN172A, GLN172B, GLN42A, GLN42B, GLN65A, GLN65B, GLU156A, GLU156B, GLU170A, GLU170B, GLU173A, GLU173B, GLU45A, GLU45B, GLU73A, GLU73B, GLY116A, GLY116B, GLY145A, GLY145B, GLY149A, GLY149B, GLY64A, GLY71A, GLY71B, GLY72A, GLY72B, HIS244A, HIS244B, HIS69A, HIS69B, HIS77A, HIS77B, LEU130A, LEU130B, LEU153A, LEU153B, LEU196B, LEU75A, LEU75B, LEU79A, LEU79B, LYS112A, LYS112B, LYS5A, LYS5B, LYS6A, LYS6B, LYS70A, LYS70B, PHE118A, PHE118B, PHE132A, PHE132B, PHE247A, PHE247B, PRO178A, PRO178B, PRO243A, PRO243B, SER115A, SER115B, SER133B, SER154A, SER154B, SER175A, SER175B, SER241A, SER241B, SER43A, SER43B, SER44A, SER44B, SER76A, SER76B, SER78A, SER78B, THR131A, THR131B, THR147A, THR147B, THR152A, THR152B, THR239A, THR239B, THR242A, THR242B, THR39A, THR67A, THR67B, TRP240A, TRP240B, TYR114A, TYR114B, TYR167A, TYR167B, TYR246A, VAL146A, VAL146B, VAL74A, VAL74B, VAL8A, VAL8B
• A-C: ALA152C, ALA155C, ALA157C, ALA158C, ALA162C, ALA165C, ALA166C, ALA176A, ALA179A, ALA180A, ALA25C, ARG148C, ARG159C, ARG208A, ARG291A, ARG73C, ASP209A, ASP270A, ASP290A, ASP56C, ASP59C, CYS177A, CYS22C, CYS54C, CYS58C, CYS70C, GLN151C, GLN15C, GLN16C, GLN19C, GLN289A, GLN53C, GLN61C, GLU181A, GLU182A, GLY164C, GLY55C, GLY57C, GLY62C, GLY77C, HIS163C, HIS244A, HIS29C, HIS51C, ILE211A, ILE52C, ILE74C, LEU147C, LEU150C, LEU168C, LEU184A, LEU249A, LEU63C, LYS20C, PHE153C, PHE161C, PHE205A, PHE206A, PHE247A, PRO178A, PRO185A, PRO243A, PRO50C, PRO60C, SER149C, SER175A, SER183A, SER18C, SER241A, SER245A, SER248A, SER294A, SER295A, THR167C, THR23C, THR242A, THR250A, TRP240A, TRP26C, TYR114A, TYR246A, TYR292A, TYR293A, TYR81C, VAL154C, VAL156C, VAL160C, VAL49C
• A-D: ASP56D, ASP59D, ASP65D, CYS54D, CYS58D, GLN53D, GLN61D, GLU45A, GLU73A, GLY35A, GLY48A, GLY55D, GLY57D, GLY62D, GLY71A, GLY72A, HIS69A, ILE36A, LEU75A, LYS70A, PRO60D, SER44A, SER49A, THR37A, THR39A, TRP38A, VAL46A, VAL74A
• B-C: ASP56C, ASP59C, ASP65C, CYS54C, CYS58C, GLN53C, GLN61C, GLU45B, GLU73B, GLY35B, GLY55C, GLY57C, GLY62C, GLY71B, GLY72B, HIS69B, LYS70B, PRO60C, SER44B, THR37B, THR39B, VAL46B, VAL74B
• B-D: ALA152D, ALA155D, ALA157D, ALA158D, ALA162D, ALA165D, ALA166D, ALA176B, ALA179B, ALA180B, ALA25D, ARG148D, ARG159D, ARG208B, ARG291B, ARG73D, ASN47D, ASP209B, ASP270B, ASP290B, ASP48D, ASP56D, ASP59D, CYS177B, CYS22D, CYS54D, CYS58D, CYS70D, GLN144B, GLN151D, GLN15D, GLN16D, GLN19D, GLN289B, GLN53D, GLN61D, GLU181B, GLU182B, GLY164D, GLY55D, GLY57D, GLY62D, GLY77D, HIS163D, HIS244B, HIS51D, ILE211B, ILE52D, ILE74D, LEU147D, LEU150D, LEU168D, LEU184B, LEU21D, LEU249B, LEU63D, LYS20D, PHE153D, PHE161D, PHE206B, PHE247B, PRO178B, PRO185B, PRO243B, PRO50D, PRO60D, SER149D, SER175B, SER183B, SER18D, SER241B, SER245B, SER248B, SER294B, SER295B, THR167D, THR23D, THR242B, THR250B, TRP240B, TRP26D, TYR114B, TYR246B, TYR292B, TYR293B, TYR81D, VAL154D, VAL156D, VAL160D, VAL49D