3DSF

crystal structure of anti-osteopontin antibody 23c3 in complex with w43a mutated epitope peptide

• Total interactions analyzed: 3
• Total true interactions: 3
• Strongest Interaction:
  • Chains: H-P
  • Int. Res.: 32
  • Norm. En. per Res.: -5.1943
• Hub Node: L(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
L-H	-36.6312	-2.7109	-432.494	-471.8361	180	13	8	17250	0	5	5
L-P	-6.4841	0.0	-13.8093	-20.2934	12	0	0	654	0	0	0
H-P	-43.2325	-25.0995	-97.8852	-166.2172	32	5	0	2822	1	4	2

Interface residues

• L-H: ALA122L, ALA123L, ALA128H, ALA133H, ALA169L, ALA171H, ALA213L, ALA33H, ALA34L, ALA49H, ALA50L, ALA55L, ALA63H, ARG100H, ARG211L, ARG38H, ARG50H, ARG52H, ASN136H, ASN137L, ASN138L, ASN146H, ASN161L, ASN210L, ASN35H, ASP104H, ASP167L, ASP170L, ASP56L, ASP64H, CYS134L, CYS143H, CYS88L, CYS98H, GLN101H, GLN108H, GLN124L, GLN174H, GLN37L, GLN38L, GLN39H, GLN40L, GLN45L, GLN89L, GLU1H, GLU46H, GLU6H, GLY101L, GLY103H, GLY107H, GLY109H, GLY129L, GLY130H, GLY130L, GLY131H, GLY132H, GLY142H, GLY158L, GLY165H, GLY41L, GLY42H, GLY44H, GLY93L, GLY99L, HIS167H, HIS90L, ILE117L, ILE134H, ILE205L, ILE213H, ILE51H, LEU125L, LEU127H, LEU136L, LEU141H, LEU144H, LEU160L, LEU173H, LEU179L, LEU180H, LEU33L, LEU45H, LEU46L, LEU47L, LYS103L, LYS207L, LYS211H, LYS39L, LYS42L, LYS43H, LYS67H, MET102H, MET138H, MET175L, MET34H, MET95H, PHE118L, PHE135L, PHE139L, PHE169H, PHE209L, PHE32L, PHE91L, PHE96L, PHE98L, PRO119L, PRO120L, PRO126H, PRO129H, PRO170H, PRO44L, PRO95L, SER100L, SER116L, SER121L, SER123H, SER126L, SER127L, SER131L, SER135H, SER162L, SER164H, SER165L, SER174L, SER175H, SER176L, SER177L, SER181H, SER182H, SER183H, SER208L, SER214H, SER31L, SER43L, SER65H, THR114L, THR140H, THR164L, THR168H, THR172L, THR178L, THR179H, THR180L, THR185H, THR60H, THR85L, THR94L, THR97L, TRP106H, TRP157H, TRP163L, TRP191H, TRP35L, TRP36H, TRP47H, TYR105H, TYR125H, TYR173L, TYR1L, TYR36L, TYR49L, TYR61H, TYR62H, TYR86L, TYR87L, TYR97H, VAL115L, VAL124H, VAL132L, VAL133L, VAL139H, VAL145H, VAL159L, VAL166H, VAL172H, VAL184H, VAL216H, VAL37H, VAL48H, VAL99H
• L-P: ASN53L, GLN50P, GLY93L, LEU44P, PHE32L, PHE91L, PHE96L, PRO48P, SER49P, THR94L, TRP92L, TYR49L
• H-P: ALA33H, ARG100H, ARG50H, ARG52H, ARG74H, ASN30H, ASN35H, ASN45P, ASN56H, ASN57H, ASP104H, ASP47P, GLN101H, GLN50P, GLN54H, ILE31H, ILE51H, LEU44P, MET102H, MET34H, PHE27H, PHE29H, PRO46P, PRO48P, SER49P, SER53H, SER55H, THR28H, THR59H, TYR32H, TYR58H, TYR61H