3DRY

x-ray crystal structure of human kctd5 protein crystallized in low- salt buffer

• Total interactions analyzed: 10
• Total true interactions: 10
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 146
  • Norm. En. per Res.: -3.1929
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-64.3184	-38.6343	-334.848	-437.8008	152	28	10	14201	3	47	33
A-C	0.0	5.3264	-0.0055	5.3209	7	0	0	9	0	2	3
A-D	0.0	5.0344	-0.0075	5.0268	5	0	0	8	0	2	3
A-E	-59.0173	-44.62	-313.364	-417.0014	147	22	11	13680	4	50	27
B-C	-91.9526	-49.532	-324.677	-466.1615	146	23	10	13910	5	50	29
B-D	0.0	4.8332	-0.0062	4.827	7	0	0	8	0	2	3
B-E	0.0	4.6044	-0.0054	4.599	6	0	0	7	0	2	3
C-D	-52.98	-59.2413	-338.302	-450.5233	151	27	12	14233	5	51	28
C-E	0.0	5.2511	-0.0012	5.2499	4	0	0	3	0	2	3
D-E	-65.6755	-63.1933	-293.425	-422.2939	153	27	9	12793	3	50	33

Interface residues

• A-B: ALA118B, ALA199B, ALA89B, ARG107A, ARG145B, ARG159B, ARG47A, ARG59A, ARG64A, ARG72B, ARG94B, ASN104A, ASN114A, ASN114B, ASN49B, ASP116A, ASP116B, ASP177A, ASP79B, ASP83B, ASP85B, ASP93B, ASP95B, CYS203A, CYS203B, GLN151A, GLN151B, GLN162B, GLN170A, GLN183A, GLN183B, GLN198B, GLN60A, GLU119B, GLU120B, GLU124B, GLU125B, GLU127B, GLU165A, GLU167A, GLU182A, GLU182B, GLU200A, GLU200B, GLU208A, GLU208B, GLY100A, GLY109A, GLY121B, GLY178A, GLY188A, GLY188B, GLY51B, GLY52B, HIS108A, HIS156A, HIS156B, HIS210A, ILE113A, ILE113B, ILE187A, ILE187B, ILE92B, LEU103A, LEU106A, LEU111A, LEU117A, LEU117B, LEU123B, LEU161B, LEU168A, LEU184A, LEU184B, LEU202A, LEU202B, LEU209A, LEU48A, LEU56A, LEU62A, LEU80B, LEU91B, LYS110A, LYS115A, LYS115B, LYS141A, LYS148A, LYS155A, LYS155B, LYS180A, LYS207A, LYS44A, LYS84B, MET171A, MET175A, PHE128B, PHE181A, PHE201A, PHE201B, PHE55A, PHE69B, PRO101A, PRO153A, PRO153B, PRO96B, SER150B, SER173A, SER176A, SER186A, SER186B, SER189A, SER189B, SER190A, SER190B, SER206A, SER206B, SER82B, THR149B, THR169A, THR174A, THR53A, THR53B, THR57A, THR58A, THR61A, THR97B, TRP179A, TRP179B, TRP45A, TYR129B, TYR158B, TYR54A, TYR54B, TYR90B, TYR98B, VAL112A, VAL122B, VAL152A, VAL152B, VAL154A, VAL154B, VAL157B, VAL160B, VAL172A, VAL185A, VAL185B, VAL204A, VAL204B, VAL205A, VAL205B, VAL42A, VAL46A, VAL50B
• A-C: ASP116A, ASP116C, GLN183A, GLN183C, LEU184A, LYS115A, PHE181A
• A-D: ASP116A, ASP116D, GLN183A, GLN183D, PHE181D
• A-E: ALA118A, ALA199A, ALA89A, ARG107E, ARG145A, ARG159A, ARG47E, ARG59E, ARG94A, ASN104E, ASN114A, ASN114E, ASN49A, ASP116A, ASP116E, ASP177E, ASP197A, ASP79A, ASP81A, ASP83A, ASP85A, ASP93A, ASP95A, CYS203A, CYS203E, GLN151A, GLN162A, GLN170E, GLN183A, GLN183E, GLN198A, GLN60E, GLU119A, GLU120A, GLU124A, GLU125A, GLU127A, GLU165E, GLU167E, GLU182A, GLU182E, GLU196A, GLU200E, GLU208A, GLU208E, GLU86A, GLY100E, GLY109E, GLY121A, GLY178E, GLY188A, GLY188E, GLY51A, GLY52A, HIS108E, HIS156A, HIS210E, ILE113A, ILE113E, ILE187A, ILE187E, ILE92A, LEU103E, LEU106E, LEU111E, LEU117A, LEU117E, LEU123A, LEU161A, LEU168E, LEU184A, LEU184E, LEU202A, LEU209A, LEU209E, LEU48A, LEU48E, LEU56E, LEU62E, LEU80A, LEU91A, LYS110E, LYS115A, LYS115E, LYS141E, LYS148E, LYS155A, LYS180E, LYS207E, LYS44E, LYS84A, MET171E, MET175E, PHE128A, PHE181E, PHE201E, PHE55E, PHE69A, PRO101E, PRO153A, PRO96A, SER150A, SER173E, SER176E, SER186A, SER186E, SER189A, SER189E, SER190A, SER190E, SER206A, SER206E, SER82A, THR149A, THR169E, THR174E, THR53A, THR53E, THR57E, THR58E, THR61E, THR87A, THR97A, TRP179E, TRP45E, TYR129A, TYR158A, TYR54A, TYR54E, TYR90A, TYR98A, VAL112E, VAL122A, VAL152A, VAL154A, VAL154E, VAL157A, VAL160A, VAL172E, VAL185A, VAL185E, VAL204A, VAL204E, VAL205A, VAL205E, VAL46E, VAL50A
• B-C: ALA118C, ALA89C, ARG107B, ARG145C, ARG159C, ARG47B, ARG59B, ARG72C, ARG94C, ASN104B, ASN114B, ASN114C, ASN49C, ASP116B, ASP116C, ASP146C, ASP177B, ASP83C, ASP85C, ASP93C, ASP95C, CYS203B, CYS203C, GLN151C, GLN162C, GLN164B, GLN170B, GLN183B, GLN183C, GLN198C, GLN60B, GLU119C, GLU120C, GLU124C, GLU125C, GLU127C, GLU165B, GLU167B, GLU182B, GLU182C, GLU200B, GLU208B, GLU208C, GLU86C, GLY100B, GLY109B, GLY121C, GLY178B, GLY188B, GLY188C, GLY51C, GLY52C, HIS108B, HIS156B, HIS156C, HIS210B, ILE113B, ILE113C, ILE187C, ILE92C, LEU103B, LEU106B, LEU111B, LEU117B, LEU117C, LEU123C, LEU161C, LEU168B, LEU184B, LEU184C, LEU202B, LEU202C, LEU209B, LEU48B, LEU48C, LEU56B, LEU62B, LEU80C, LEU91C, LYS110B, LYS115B, LYS115C, LYS141B, LYS141C, LYS148B, LYS155C, LYS180B, LYS207B, LYS44B, LYS84C, MET171B, MET175B, PHE128C, PHE181B, PHE201B, PHE55B, PHE69C, PRO101B, PRO153C, PRO96C, SER147C, SER150C, SER173B, SER176B, SER186B, SER186C, SER189B, SER189C, SER206B, SER206C, SER43B, SER82C, THR149C, THR169B, THR174B, THR53B, THR53C, THR57B, THR58B, THR61B, THR97C, TRP179B, TRP179C, TRP45B, TYR129C, TYR158C, TYR54B, TYR54C, TYR90C, TYR98C, VAL112B, VAL122C, VAL152C, VAL154B, VAL154C, VAL157C, VAL160C, VAL172B, VAL185B, VAL185C, VAL204B, VAL204C, VAL205B, VAL205C, VAL46B, VAL50C
• B-D: ASP116B, ASP116D, GLN151D, GLN183B, GLN183D, LYS180B, PHE181B
• B-E: ASP116B, ASP116E, GLN183B, GLN183E, LYS115E, PHE181E
• C-D: ALA118D, ARG107C, ARG145D, ARG159D, ARG47C, ARG59C, ARG64C, ARG94D, ASN104C, ASN114C, ASN114D, ASN49D, ASP116C, ASP116D, ASP146D, ASP177C, ASP79D, ASP83D, ASP85D, ASP93D, ASP95D, CYS203C, CYS203D, GLN151C, GLN151D, GLN162D, GLN170C, GLN183C, GLN183D, GLN60C, GLU119D, GLU120D, GLU124D, GLU125D, GLU127D, GLU165C, GLU167C, GLU182C, GLU182D, GLU196D, GLU200C, GLU200D, GLU208C, GLU208D, GLU86D, GLY100C, GLY109C, GLY121D, GLY178C, GLY188C, GLY188D, GLY51D, GLY52D, HIS108C, HIS156C, HIS156D, HIS210C, ILE113C, ILE113D, ILE187C, ILE187D, ILE92D, LEU103C, LEU106C, LEU111C, LEU117C, LEU117D, LEU123D, LEU161D, LEU168C, LEU184C, LEU184D, LEU202C, LEU202D, LEU209C, LEU209D, LEU48C, LEU48D, LEU56C, LEU62C, LEU80D, LEU91D, LYS110C, LYS115C, LYS115D, LYS141C, LYS148D, LYS155D, LYS180C, LYS207C, LYS207D, LYS44C, LYS84D, MET171C, MET175C, PHE128D, PHE181C, PHE201C, PHE55C, PHE69D, PRO101C, PRO153C, PRO153D, PRO96D, SER147D, SER150D, SER173C, SER176C, SER186C, SER186D, SER189C, SER189D, SER190C, SER190D, SER206C, SER206D, SER82D, THR149D, THR169C, THR174C, THR53C, THR53D, THR57C, THR58C, THR61C, THR97D, TRP179C, TRP179D, TRP45C, TYR158D, TYR191C, TYR54C, TYR54D, TYR90D, TYR98D, VAL112C, VAL122D, VAL152D, VAL154C, VAL154D, VAL157D, VAL160D, VAL172C, VAL185C, VAL185D, VAL204C, VAL204D, VAL205C, VAL205D, VAL46C, VAL50D
• C-E: ASP116C, ASP116E, GLN183E, PHE181C
• D-E: ALA118E, ALA199E, ALA89E, ARG107D, ARG145E, ARG159E, ARG38D, ARG47D, ARG59D, ARG64D, ARG94E, ASN104D, ASN114D, ASN114E, ASN49E, ASP116D, ASP116E, ASP146E, ASP177D, ASP83E, ASP85E, ASP93E, ASP95E, CYS203D, CYS203E, GLN151E, GLN162E, GLN170D, GLN183D, GLN183E, GLN198E, GLN60D, GLU119E, GLU120E, GLU124E, GLU125E, GLU127E, GLU165D, GLU166D, GLU167D, GLU182D, GLU182E, GLU200D, GLU208D, GLU208E, GLU86E, GLY100D, GLY109D, GLY121E, GLY178D, GLY188E, GLY40D, GLY51E, GLY52E, HIS108D, HIS156D, HIS156E, HIS210D, ILE113D, ILE113E, ILE187D, ILE187E, ILE92E, LEU103D, LEU106D, LEU111D, LEU117D, LEU117E, LEU123E, LEU161E, LEU168D, LEU184D, LEU184E, LEU202D, LEU202E, LEU209D, LEU209E, LEU48D, LEU56D, LEU62D, LEU80E, LEU91E, LYS110D, LYS115D, LYS115E, LYS141D, LYS148D, LYS155E, LYS180D, LYS207D, LYS44D, LYS84E, MET171D, MET175D, PHE128E, PHE181D, PHE201D, PHE55D, PHE69E, PHE99D, PRO101D, PRO153E, PRO39D, PRO96E, SER150E, SER173D, SER176D, SER186D, SER186E, SER189D, SER189E, SER190D, SER206D, SER206E, SER43D, SER82E, THR149E, THR169D, THR174D, THR53D, THR53E, THR57D, THR58D, THR61D, THR87E, THR97E, TRP179D, TRP179E, TRP45D, TYR105D, TYR129E, TYR158E, TYR54D, TYR54E, TYR90E, TYR98E, VAL112D, VAL122E, VAL152E, VAL154D, VAL154E, VAL157E, VAL160E, VAL172D, VAL185D, VAL185E, VAL204D, VAL204E, VAL205D, VAL205E, VAL42D, VAL46D, VAL50E