3DPY

protein farnesyltransferase complexed with fpp and caged tkcvim substrate

• Total interactions analyzed: 3
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 307
  • Norm. En. per Res.: -4.1989
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-176.3209	-124.2777	-988.47	-1289.0686	307	37	16	36442	13	99	106
A-C	0.0	0.0	-24.5536	-24.5536	14	0	1	1113	0	0	0
B-C	0.0	0.0	-34.7243	-34.7243	40	2	0	2115	0	0	0

Interface residues

• A-B: ALA123B, ALA128A, ALA129A, ALA151B, ALA197A, ALA202A, ALA247B, ALA276A, ALA313A, ALA322B, ALA334B, ALA345A, ALA92B, ALA98B, ARG100B, ARG104A, ARG112A, ARG137A, ARG138A, ARG173A, ARG202B, ARG206A, ARG231B, ARG232A, ARG240A, ARG27B, ARG280B, ARG283B, ARG291B, ARG32B, ARG352A, ARG357A, ARG361A, ARG84B, ARG87B, ARG97A, ASN127A, ASN130A, ASN165A, ASN199A, ASN233A, ASN234A, ASN234B, ASN238A, ASN246A, ASN269B, ASN273A, ASN278A, ASN293B, ASN81A, ASP110A, ASP125B, ASP196A, ASP200B, ASP230A, ASP286A, ASP317A, ASP320B, ASP321A, ASP349A, ASP37B, ASP38B, ASP82A, ASP91B, ASP97B, CYS104B, CYS127B, CYS133B, CYS232B, CYS254B, CYS292B, CYS95B, GLN128B, GLN146B, GLN162A, GLN167A, GLN195A, GLN204A, GLN207A, GLN211A, GLN233B, GLN239A, GLN275B, GLN281B, GLN285A, GLN289B, GLN318B, GLN332B, GLN333B, GLN364A, GLN36B, GLN48B, GLN80A, GLN88B, GLN89A, GLU131B, GLU198B, GLU229A, GLU236B, GLU246B, GLU274A, GLU285B, GLU29B, GLU320A, GLU324A, GLU33B, GLU347A, GLU354A, GLU41B, GLU47B, GLU94A, GLU94B, GLY141B, GLY142B, GLY143B, GLY145B, GLY196B, GLY197B, GLY237B, GLY240B, GLY241B, GLY244B, GLY249B, GLY250B, GLY282A, GLY286B, GLY287B, GLY290B, GLY319B, GLY360A, GLY83A, GLY85B, HIS135A, HIS149B, HIS170A, HIS171A, HIS194B, HIS201A, HIS205A, HIS241A, HIS248B, HIS272A, HIS306A, HIS30B, HIS312B, HIS316B, HIS327B, HIS331B, ILE107B, ILE121B, ILE163B, ILE239B, ILE267A, ILE283A, ILE351A, ILE359A, ILE46B, ILE90A, ILE91A, LEU103B, LEU107A, LEU108B, LEU126A, LEU130B, LEU132B, LEU150B, LEU192B, LEU226A, LEU227A, LEU269A, LEU270B, LEU273B, LEU274B, LEU280A, LEU284A, LEU289A, LEU295B, LEU308B, LEU311B, LEU315B, LEU323B, LEU335B, LEU344A, LEU35B, LEU363A, LEU82B, LEU86B, LEU89B, LEU96B, LYS164A, LYS198A, LYS228A, LYS268A, LYS271B, LYS281A, LYS294B, LYS346A, LYS348A, LYS353A, LYS356B, LYS366A, LYS95A, MET193B, MET245B, MET266A, MET282B, MET325B, MET329B, PHE103A, PHE129B, PHE136A, PHE140B, PHE242A, PHE284B, PHE288B, PHE314A, PHE330B, PHE360B, PHE96A, PRO101B, PRO144B, PRO148B, PRO152B, PRO243B, PRO271A, PRO309A, PRO321B, PRO79A, PRO84A, PRO86A, SER235A, SER245A, SER25B, SER272B, SER275A, SER279B, SER307A, SER308A, SER324B, SER326B, SER362A, SER365A, SER39B, SER45B, SER85A, SER93A, SER99B, THR124B, THR132A, THR153B, THR252B, THR278B, THR350A, THR42B, THR44B, THR90B, TRP102B, TRP106B, TRP134A, TRP169A, TRP203A, TRP208A, TRP216A, TRP228B, TRP235B, TRP237A, TRP276B, TRP277A, TRP328B, TRP356A, TYR100A, TYR105B, TYR131A, TYR147B, TYR166A, TYR180B, TYR200A, TYR24B, TYR250A, TYR251B, TYR279A, TYR310A, TYR338B, TYR355A, TYR358A, TYR92A, TYR93B, VAL122B, VAL126B, VAL133A, VAL139A, VAL174A, VAL195B, VAL199B, VAL201B, VAL231A, VAL236A, VAL242B, VAL270A, VAL277B, VAL316A, VAL385B, VAL40B, VAL43B, VAL78A, VAL87A, VAL88A
• A-C: ALA128A, ALA129A, ASN130A, ASN165A, GLN162A, GLN167A, HIS201A, ILE2008C, LYS164A, MET2009C, THR132A, TYR131A, TYR166A, VAL2007C
• B-C: ALA151B, ALA155B, ALA98B, ARG100B, ARG202B, ASP200B, CYS254B, CYS299B, CYS95B, GLN146B, GLU198B, GLY141B, GLY142B, GLY143B, GLY250B, HIS149B, HIS194B, HIS248B, HIS362B, ILE2008C, LEU150B, LEU96B, MET193B, MET2009C, PHE140B, PRO101B, PRO152B, SER99B, THR153B, TRP102B, TRP106B, TRP303B, TYR105B, TYR147B, TYR154B, TYR251B, TYR300B, TYR361B, TYR365B, VAL2007C