3DPL

structural insights into nedd8 activation of cullin-ring ligases: conformational control of conjugation.

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: C-R
  • Int. Res.: 186
  • Norm. En. per Res.: -5.0871
• Hub Node: C(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
C-R	-256.5309	-29.5125	-660.163	-946.2065	186	44	18	25745	2	55	45

Interface residues

• C-R: ALA29R, ALA31R, ALA34R, ALA487C, ALA520C, ALA523C, ALA533C, ALA535C, ALA605C, ALA63R, ALA71R, ALA78R, ARG21R, ARG452C, ARG495C, ARG538C, ARG569C, ARG609C, ARG611C, ARG714C, ARG99R, ASN28R, ASN491C, ASN507C, ASN527C, ASN532C, ASN579C, ASN586C, ASN59R, ASN607C, ASN669C, ASN76R, ASP36R, ASP465C, ASP488C, ASP499C, ASP524C, ASP553C, ASP592C, CYS56R, CYS75R, GLN104R, GLN590C, GLN608C, GLN60R, GLN670C, GLN693C, GLN709C, GLN716C, GLU102R, GLU23R, GLU541C, GLU550C, GLU552C, GLU559C, GLU55R, GLU587C, GLU594C, GLU612C, GLU67R, GLU702C, GLU703C, GLU705C, GLU717C, GLU758C, GLU762C, GLY107R, GLY534C, GLY568C, GLY580C, GLY589C, GLY684C, GLY706C, GLY73R, HIS108R, HIS566C, HIS572C, HIS574C, HIS575C, HIS763C, HIS77R, HIS82R, ILE37R, ILE463C, ILE528C, ILE530C, ILE555C, ILE581C, ILE582C, ILE689C, ILE707C, ILE712C, ILE761C, LEU32R, LEU464C, LEU493C, LEU506C, LEU521C, LEU531C, LEU547C, LEU551C, LEU554C, LEU571C, LEU576C, LEU593C, LEU600C, LEU603C, LEU637C, LEU648C, LEU688C, LEU710C, LEU713C, LEU760C, LYS105R, LYS19R, LYS20R, LYS25R, LYS26R, LYS455C, LYS492C, LYS511C, LYS529C, LYS542C, LYS563C, LYS570C, LYS585C, LYS685C, LYS724C, LYS764C, LYS89R, MET496C, MET50R, MET577C, PHE103R, PHE22R, PHE584C, PHE604C, PHE672C, PHE81R, PRO522C, PRO548C, PRO556C, PRO610C, SER503C, SER525C, SER537C, SER539C, SER540C, SER567C, SER578C, SER62R, SER667C, SER85R, THR459C, THR549C, THR583C, THR596C, THR597C, THR69R, TRP27R, TRP33R, TRP35R, TRP536C, TRP573C, TRP606C, TRP72R, TRP759C, TYR106R, TYR489C, TYR562C, TYR591C, TYR765C, VAL24R, VAL30R, VAL38R, VAL39R, VAL502C, VAL526C, VAL545C, VAL558C, VAL595C, VAL602C, VAL647C, VAL668C, VAL70R, VAL74R