3DJC

crystal structure of pantothenate kinase from legionella pneumophila

• Total interactions analyzed: 66
• Total true interactions: 28
• Strongest Interaction:
  • Chains: H-I
  • Int. Res.: 49
  • Norm. En. per Res.: -4.5695
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-129.7839	-62.6569	-657.785	-850.2257	202	29	32	26884	8	35	27
A-C	0.0	0.0	-0.0073	-0.0073	4	0	0	4	0	2	1
A-D	-28.7961	-68.9322	-120.736	-218.4644	52	4	2	4590	7	21	22
A-E	-31.1223	-68.9706	-115.089	-215.1818	55	5	2	4772	8	23	22
A-H	0.0	0.0	-0.4452	-0.4452	10	0	0	120	0	3	4
B-C	-30.5698	-72.4361	-126.369	-229.375	51	9	2	5013	4	21	22
B-E	0.0	0.0	-0.0413	-0.0413	3	0	0	16	0	1	1
B-F	-18.8391	-28.8954	-111.496	-159.2304	52	8	2	4846	5	21	22
B-H	-5.8866	-4.2219	-20.6507	-30.7593	28	2	0	1168	0	10	11
C-D	-110.6086	-23.7423	-647.323	-781.6738	195	26	32	25302	5	29	25
C-F	-8.2361	-27.988	-107.082	-143.3061	54	9	2	4482	4	23	20
D-E	-40.9272	-31.5786	-114.749	-187.2548	55	7	2	4740	6	22	21
E-F	-118.1374	-49.8133	-614.195	-782.1457	178	29	27	24010	7	26	26
F-H	-12.6645	3.3044	-71.3786	-80.7387	59	5	2	3171	0	13	10
F-I	-7.4247	0.8038	-45.7549	-52.3758	44	2	0	2107	0	19	12
F-J	0.0	14.4977	-23.1058	-8.6081	26	0	0	1288	0	5	7
G-H	-102.1621	-42.6367	-642.588	-787.3869	190	22	30	25724	7	33	28
G-I	0.0	0.0	-0.0072	-0.0072	3	0	0	6	0	2	1
G-J	-18.7936	-72.4504	-111.396	-202.64	54	6	2	4758	5	23	23
G-K	-19.7371	-69.0169	-135.546	-224.3	57	4	2	5167	7	23	22
G-L	0.0	0.0	-0.0052	-0.0052	2	0	0	4	0	1	1
H-I	-27.5781	-71.2147	-125.112	-223.9048	49	11	2	4823	6	21	21
H-K	0.0	0.0	-0.0157	-0.0157	5	0	0	10	0	2	1
H-L	-27.9923	-70.5199	-131.117	-229.6292	56	4	2	5165	6	22	22
I-J	-98.1158	-68.6065	-624.174	-790.8963	185	24	30	24962	9	30	28
I-L	-36.0478	-87.3891	-125.195	-248.6319	55	6	2	4852	8	22	22
J-K	-29.2067	-62.2678	-130.899	-222.3735	55	8	2	5363	6	22	22
K-L	-115.8858	-30.5851	-611.05	-757.5209	179	23	28	23712	6	26	26

Interface residues

• A-B: ALA107A, ALA107B, ALA133A, ALA133B, ALA138A, ALA138B, ALA144B, ALA149A, ALA149B, ALA158A, ALA158B, ALA160A, ALA160B, ALA166A, ALA166B, ALA199A, ALA199B, ALA211A, ALA211B, ARG100A, ARG100B, ARG109A, ARG109B, ARG155A, ARG155B, ARG182A, ARG182B, ARG206A, ARG206B, ASN101A, ASN101B, ASN164A, ASN164B, ASN96B, ASN9A, ASN9B, ASP108A, ASP108B, ASP159A, ASP159B, ASP69A, ASP69B, CYS137A, CYS137B, CYS200A, CYS200B, GLN189A, GLN189B, GLN205A, GLN205B, GLN232A, GLN232B, GLN67A, GLN67B, GLN88A, GLU104A, GLU104B, GLU177A, GLU177B, GLU186A, GLU186B, GLU202A, GLU202B, GLU210A, GLU210B, GLY106A, GLY106B, GLY147A, GLY147B, GLY148A, GLY148B, GLY153A, GLY153B, GLY181A, GLY181B, GLY191A, GLY191B, GLY195A, GLY195B, GLY198A, GLY198B, GLY8A, GLY8B, HIS208A, HIS208B, HIS209A, HIS209B, ILE110B, ILE126A, ILE126B, ILE139A, ILE150A, ILE150B, ILE185A, ILE185B, ILE188A, ILE188B, ILE204A, ILE204B, ILE207A, ILE207B, ILE97A, ILE97B, LEU146A, LEU146B, LEU151A, LEU151B, LEU154A, LEU154B, LEU156A, LEU156B, LEU161A, LEU161B, LEU168A, LEU168B, LEU197A, LEU197B, LEU203A, LEU203B, LEU234B, LYS163A, LYS163B, LYS167A, LYS167B, LYS175B, LYS201A, LYS201B, LYS231A, LYS231B, LYS98A, LYS98B, PHE136A, PHE136B, PHE212A, PHE212B, PHE229B, PRO102A, PRO152A, PRO152B, PRO169A, PRO169B, PRO66A, PRO66B, SER10A, SER10B, SER140B, SER157A, SER157B, SER162A, SER162B, SER178A, SER178B, SER183A, SER183B, SER187A, SER187B, SER190A, SER190B, SER30B, SER63A, SER63B, THR132A, THR132B, THR134A, THR134B, THR135A, THR135B, THR165A, THR165B, THR176A, THR176B, THR184A, THR184B, TYR145A, TYR145B, TYR193A, TYR193B, TYR194A, TYR194B, TYR99A, TYR99B, VAL103A, VAL103B, VAL105A, VAL105B, VAL171A, VAL171B, VAL179A, VAL179B, VAL180A, VAL180B, VAL192A, VAL192B, VAL196A, VAL196B, VAL64A, VAL64B, VAL65A, VAL65B, VAL68A, VAL68B, VAL7B
• A-C: ALA166C, GLU172A, LYS167C, SER170A
• A-D: ARG155A, ARG25A, ARG27A, ARG47A, ARG47D, ASN49A, ASN50A, ASP159A, ASP36D, GLN67D, GLU172A, GLU37D, GLU48A, GLU54D, GLY14A, GLY39D, HIS11A, HIS28A, ILE12A, ILE40A, ILE40D, LEU24A, LEU38A, LEU38D, LEU42A, LEU42D, LEU46A, LYS31A, LYS31D, LYS43A, LYS43D, LYS78D, PHE26A, PHE41A, PHE41D, PRO53D, PRO66D, SER10A, SER170A, SER30A, SER33A, SER33D, SER35D, SER44A, SER44D, SER71D, THR29A, THR34D, TYR13A, TYR79D, VAL32D, VAL45A
• A-E: ARG155E, ARG25E, ARG27E, ARG47A, ARG47E, ASN49E, ASN50E, ASP159E, ASP36A, ASP69A, GLN67A, GLU172E, GLU37A, GLU48E, GLY14E, GLY39A, HIS11E, HIS28A, HIS28E, ILE12E, ILE40A, ILE40E, LEU24E, LEU38A, LEU42E, LEU46E, LYS31A, LYS31E, LYS43A, LYS43E, LYS78A, PHE26E, PHE41A, PHE41E, PRO53A, PRO66A, SER10E, SER162E, SER170E, SER30E, SER33A, SER33E, SER35A, SER44A, SER44E, SER71A, THR29A, THR29E, THR34A, TYR13E, TYR70A, TYR79A, VAL171E, VAL32A, VAL45E
• A-H: ALA144H, ALA211A, ARG100A, ARG206A, ASN122H, ASN96H, GLU210A, HIS141H, LYS142H, LYS98H
• B-C: ARG25C, ARG27C, ARG47B, ARG47C, ASN49C, ASN50C, ASP36B, GLU37B, GLU48B, GLU48C, GLU54B, GLY14C, GLY15C, GLY39B, HIS11C, HIS28B, HIS28C, ILE12C, ILE40B, ILE40C, LEU24C, LEU38B, LEU42C, LEU46C, LYS23C, LYS31B, LYS31C, LYS43B, LYS43C, LYS78B, PHE26C, PHE41B, PHE41C, PRO53B, SER10C, SER30C, SER33B, SER33C, SER35B, SER44B, SER44C, SER71B, SER74B, THR29B, THR29C, THR34B, TYR13C, TYR70B, TYR79B, VAL32B, VAL45C
• B-E: ALA166B, LYS167B, SER170E
• B-F: ARG155B, ARG25B, ARG27B, ARG47B, ARG47F, ASN49B, ASN50B, ASP159B, ASP36F, GLN67F, GLU172B, GLU37F, GLU48B, GLU54F, GLY14B, GLY39F, HIS11B, HIS28B, ILE12B, ILE40B, ILE40F, LEU24B, LEU38F, LEU42B, LEU46B, LYS23B, LYS31B, LYS31F, LYS43B, LYS43F, LYS78F, PHE26B, PHE41B, PHE41F, PRO53F, PRO66F, SER10B, SER170B, SER30B, SER33B, SER33F, SER35F, SER44B, SER44F, SER71F, THR29B, THR34F, TYR13B, TYR70F, TYR79F, VAL32F, VAL45B
• B-H: ARG182B, ASN122H, ASP230B, GLN189B, GLU172B, GLU177B, GLU186B, GLY181B, GLY94H, HIS118H, HIS141H, ILE173B, ILE174B, LYS142H, LYS143H, LYS175B, LYS231B, LYS92H, MET253H, PHE120H, PRO121H, SER119H, SER178B, THR117H, THR176B, TYR194B, VAL179B, VAL180B
• C-D: ALA107D, ALA133C, ALA133D, ALA138C, ALA138D, ALA144C, ALA144D, ALA149C, ALA149D, ALA158C, ALA158D, ALA160C, ALA160D, ALA166C, ALA166D, ALA199C, ALA199D, ALA211C, ALA211D, ARG100C, ARG100D, ARG109D, ARG155C, ARG155D, ARG182C, ARG182D, ARG206C, ARG206D, ASN101C, ASN101D, ASN164C, ASN164D, ASN213C, ASN96D, ASN9C, ASN9D, ASP159C, ASP159D, ASP69D, CYS137C, CYS137D, CYS200C, CYS200D, GLN189C, GLN189D, GLN205C, GLN205D, GLN232C, GLN232D, GLN67C, GLN67D, GLU104C, GLU104D, GLU177C, GLU177D, GLU186C, GLU186D, GLU202C, GLU202D, GLU210C, GLU210D, GLY106C, GLY106D, GLY147C, GLY147D, GLY148C, GLY148D, GLY153C, GLY153D, GLY181C, GLY181D, GLY191C, GLY191D, GLY195C, GLY195D, GLY198C, GLY198D, GLY8C, GLY8D, HIS208C, HIS208D, HIS209C, HIS209D, ILE126C, ILE126D, ILE139C, ILE150C, ILE150D, ILE185C, ILE185D, ILE188C, ILE188D, ILE204C, ILE204D, ILE207C, ILE207D, ILE97C, ILE97D, LEU146C, LEU146D, LEU151C, LEU151D, LEU154C, LEU154D, LEU156C, LEU156D, LEU161C, LEU161D, LEU168C, LEU197C, LEU197D, LEU203C, LEU203D, LEU234C, LYS163C, LYS163D, LYS167C, LYS175C, LYS175D, LYS201C, LYS201D, LYS98C, LYS98D, PHE136C, PHE136D, PHE212C, PHE212D, PHE229C, PHE229D, PRO102C, PRO102D, PRO152C, PRO152D, PRO169C, PRO66C, PRO66D, SER10C, SER10D, SER140D, SER157C, SER157D, SER162C, SER162D, SER178C, SER178D, SER183C, SER183D, SER187C, SER187D, SER190C, SER190D, SER30C, SER30D, SER63D, THR132C, THR132D, THR134C, THR134D, THR135C, THR135D, THR165C, THR165D, THR176C, THR176D, THR184C, THR184D, TYR145C, TYR145D, TYR193C, TYR193D, TYR194C, TYR194D, TYR99C, TYR99D, VAL103C, VAL103D, VAL105C, VAL105D, VAL171D, VAL179C, VAL179D, VAL180C, VAL180D, VAL192C, VAL192D, VAL196C, VAL196D, VAL64C, VAL64D, VAL65C, VAL65D, VAL68C, VAL68D, VAL7C, VAL7D
• C-F: ARG155F, ARG25F, ARG27F, ARG47C, ARG47F, ASN49F, ASN50F, ASP159F, ASP36C, ASP69C, GLN67C, GLU172F, GLU37C, GLU37F, GLU48F, GLU54C, GLY14F, GLY39C, HIS11F, HIS28C, HIS28F, ILE12F, ILE40C, ILE40F, LEU24F, LEU38C, LEU42F, LEU46F, LYS31C, LYS31F, LYS43C, LYS43F, LYS78C, PHE26F, PHE41C, PHE41F, PRO53C, PRO66C, SER10F, SER30F, SER33C, SER33F, SER35C, SER44C, SER44F, SER71C, THR29F, THR34C, TYR13F, TYR70C, TYR79C, VAL171F, VAL32C, VAL45F
• D-E: ARG155D, ARG25D, ARG27D, ARG47D, ARG47E, ARG73E, ASN49D, ASN50D, ASP159D, ASP36E, ASP69E, GLN67E, GLU172D, GLU37E, GLU48D, GLU54E, GLY14D, GLY39E, HIS11D, HIS28D, ILE12D, ILE40D, ILE40E, LEU24D, LEU38E, LEU42D, LEU46D, LYS163D, LYS31D, LYS31E, LYS43D, LYS43E, LYS78E, PHE26D, PHE41D, PHE41E, PRO53E, PRO66E, SER10D, SER170D, SER30D, SER33D, SER33E, SER35E, SER44D, SER44E, SER71E, THR29D, THR34E, TYR13D, TYR70E, TYR79E, VAL171D, VAL32E, VAL45D
• E-F: ALA133E, ALA133F, ALA138E, ALA138F, ALA149E, ALA149F, ALA158E, ALA158F, ALA160E, ALA160F, ALA199E, ALA199F, ALA211E, ALA211F, ARG100E, ARG100F, ARG109E, ARG109F, ARG155E, ARG155F, ARG182E, ARG182F, ARG206E, ARG206F, ASN101E, ASN101F, ASN164E, ASN164F, ASN9E, ASN9F, ASP159E, ASP159F, CYS137E, CYS137F, CYS200E, CYS200F, GLN189E, GLN189F, GLN205E, GLN205F, GLN232E, GLN232F, GLU104E, GLU104F, GLU177E, GLU177F, GLU186E, GLU186F, GLU202E, GLU202F, GLU210E, GLU210F, GLY106E, GLY106F, GLY147E, GLY147F, GLY148E, GLY148F, GLY153E, GLY153F, GLY181E, GLY181F, GLY191E, GLY191F, GLY195E, GLY195F, GLY198E, GLY198F, GLY8F, HIS208E, HIS208F, HIS209E, HIS209F, ILE126E, ILE126F, ILE139E, ILE139F, ILE150E, ILE150F, ILE185E, ILE185F, ILE188E, ILE188F, ILE204E, ILE204F, ILE207E, ILE207F, ILE97E, ILE97F, LEU146E, LEU146F, LEU151E, LEU151F, LEU154E, LEU154F, LEU156E, LEU156F, LEU161E, LEU161F, LEU197E, LEU197F, LEU203E, LEU203F, LEU234E, LEU234F, LYS163E, LYS163F, LYS175E, LYS175F, LYS201E, LYS201F, LYS231E, LYS231F, LYS98E, LYS98F, PHE136E, PHE136F, PHE212E, PHE212F, PHE229E, PHE229F, PRO102E, PRO102F, PRO152E, PRO152F, PRO66E, PRO66F, SER10E, SER10F, SER157E, SER157F, SER162E, SER162F, SER178E, SER178F, SER183E, SER183F, SER187E, SER187F, SER190E, SER190F, SER30E, THR132E, THR132F, THR134E, THR134F, THR135E, THR135F, THR165E, THR165F, THR176E, THR176F, THR184E, THR184F, TYR145E, TYR145F, TYR193E, TYR193F, TYR194E, TYR194F, TYR99E, TYR99F, VAL103E, VAL103F, VAL105E, VAL105F, VAL179E, VAL179F, VAL180E, VAL180F, VAL192E, VAL192F, VAL196E, VAL196F, VAL64E, VAL64F, VAL65E, VAL65F
• F-H: ALA250H, ALA251F, ALA251H, ALA256F, ALA60H, ALA89F, ALA89H, ARG57F, ARG57H, ARG73F, ARG73H, ASN254F, ASN254H, ASP69H, ASP83F, ASP83H, CYS76F, GLN67H, GLN88F, GLN88H, GLY90F, GLY90H, ILE59F, ILE59H, ILE82F, ILE82H, LEU72H, LEU86F, LEU86H, LEU87F, LYS58F, LYS58H, LYS92F, LYS92H, MET252H, MET253F, MET253H, PHE80F, PHE80H, PHE85F, PHE85H, PRO102H, PRO66H, PRO84F, PRO84H, SER71H, SER74F, SER81F, SER81H, THR255F, THR255H, TYR70F, TYR70H, VAL103H, VAL68H, VAL77F, VAL77H, VAL91F, VAL91H
• F-I: ALA115F, ALA256F, ARG182I, ARG248F, ASN122F, ASN254F, ASP18F, ASP20F, ASP230I, GLN123F, GLN189I, GLU172I, GLU177I, GLU186I, GLU21F, GLY181I, GLY19F, GLY94F, HIS118F, HIS141F, ILE174I, ILE185I, LEU228I, LEU249F, LYS142F, LYS143F, LYS175I, LYS231I, LYS92F, MET252F, MET253F, PHE120F, PRO121F, SER119F, SER178I, SER183I, SER190I, SER227I, THR117F, THR176I, THR255F, TYR194I, VAL179I, VAL180I
• F-J: ALA144F, ALA211J, ARG100J, ASN101J, ASN122F, ASN213J, ASN96F, ASN96J, ASP215F, GLN123F, GLU210J, GLY147J, GLY148J, GLY94F, HIS141F, ILE97J, LEU146J, LEU95F, LYS142F, LYS143F, LYS98J, PRO102J, PRO121F, SER140F, THR117F, TYR99J
• G-H: ALA133G, ALA133H, ALA138G, ALA138H, ALA149G, ALA149H, ALA158G, ALA158H, ALA160G, ALA160H, ALA166G, ALA166H, ALA199G, ALA199H, ALA211G, ALA211H, ARG100G, ARG100H, ARG109G, ARG109H, ARG155G, ARG155H, ARG182G, ARG182H, ARG206G, ARG206H, ASN101G, ASN101H, ASN164G, ASN164H, ASN9G, ASN9H, ASP159G, ASP159H, CYS137G, CYS137H, CYS200G, CYS200H, GLN189G, GLN189H, GLN205G, GLN205H, GLN232G, GLN232H, GLN67G, GLN67H, GLU104G, GLU104H, GLU177G, GLU177H, GLU186G, GLU186H, GLU202G, GLU202H, GLU210G, GLU210H, GLY106G, GLY106H, GLY147G, GLY147H, GLY148G, GLY148H, GLY153G, GLY153H, GLY181G, GLY181H, GLY191G, GLY191H, GLY195G, GLY195H, GLY198G, GLY198H, GLY233G, GLY8G, GLY8H, HIS208G, HIS208H, HIS209G, HIS209H, ILE126G, ILE126H, ILE139G, ILE139H, ILE150G, ILE150H, ILE185G, ILE185H, ILE188G, ILE188H, ILE204G, ILE204H, ILE207G, ILE207H, ILE97G, ILE97H, LEU146G, LEU146H, LEU151G, LEU151H, LEU154G, LEU154H, LEU156G, LEU156H, LEU161G, LEU161H, LEU168G, LEU168H, LEU197G, LEU197H, LEU203G, LEU203H, LEU234H, LYS163G, LYS163H, LYS167G, LYS167H, LYS175G, LYS201G, LYS201H, LYS231G, LYS231H, LYS98G, LYS98H, PHE136G, PHE136H, PHE212G, PHE212H, PHE229H, PRO102G, PRO102H, PRO152G, PRO152H, PRO169G, PRO169H, PRO66G, PRO66H, SER10G, SER10H, SER157G, SER157H, SER162G, SER162H, SER178G, SER178H, SER183G, SER183H, SER187G, SER187H, SER190G, SER190H, SER63G, THR132G, THR132H, THR134G, THR134H, THR135G, THR135H, THR165G, THR165H, THR176G, THR176H, THR184G, THR184H, TYR145G, TYR145H, TYR193G, TYR193H, TYR194G, TYR194H, TYR99G, TYR99H, VAL103G, VAL103H, VAL105G, VAL105H, VAL171G, VAL171H, VAL179G, VAL179H, VAL180G, VAL180H, VAL192G, VAL192H, VAL196G, VAL196H, VAL64G, VAL64H, VAL65G, VAL65H, VAL68H
• G-I: GLU172G, LYS167I, SER170G
• G-J: ARG155G, ARG25G, ARG27G, ARG47G, ARG47J, ASN49G, ASN50G, ASP36J, ASP69J, GLN67J, GLU172G, GLU37J, GLU48G, GLU54J, GLY14G, GLY39J, HIS11G, HIS28G, ILE12G, ILE40G, ILE40J, LEU24G, LEU38J, LEU42G, LEU46G, LYS23G, LYS31G, LYS31J, LYS43G, LYS43J, LYS78J, PHE26G, PHE41G, PHE41J, PRO53J, PRO66J, SER10G, SER170G, SER30G, SER33G, SER33J, SER35J, SER44G, SER44J, SER71J, THR29G, THR29J, THR34J, TYR13G, TYR70J, TYR79J, VAL32G, VAL32J, VAL45G
• G-K: ARG155K, ARG25K, ARG27K, ARG47G, ARG47K, ARG73G, ASN49K, ASN50K, ASP159K, ASP36G, ASP69G, GLN67G, GLN88G, GLU172K, GLU37G, GLU48K, GLU54G, GLY14K, GLY39G, HIS11K, HIS28K, ILE12K, ILE40G, ILE40K, LEU24K, LEU38G, LEU38K, LEU42G, LEU42K, LEU46K, LYS31G, LYS31K, LYS43G, LYS43K, LYS78G, PHE26K, PHE41G, PHE41K, PRO53G, PRO66G, SER10K, SER162K, SER30K, SER33G, SER33K, SER35G, SER44G, SER44K, SER71G, THR29K, THR34G, TYR13K, TYR70G, TYR79G, VAL171K, VAL32G, VAL45K
• G-L: ARG100L, ASN101G
• H-I: ARG155I, ARG25I, ARG27I, ARG47H, ARG47I, ASN49I, ASN50I, ASP159I, ASP36H, GLN67H, GLU37H, GLU48I, GLU54H, GLY14I, GLY39H, HIS11I, HIS28I, ILE12I, ILE40H, ILE40I, LEU24I, LEU38H, LEU42I, LEU46I, LYS31H, LYS31I, LYS43H, LYS43I, LYS78H, PHE26I, PHE41H, PHE41I, PRO53H, SER10I, SER170I, SER30I, SER33H, SER33I, SER35H, SER44H, SER44I, SER71H, THR29I, THR34H, TYR13I, TYR70H, TYR79H, VAL32H, VAL45I
• H-K: ALA166K, GLU172K, LYS167H, SER170H, VAL171K
• H-L: ARG155H, ARG25H, ARG27H, ARG47H, ARG47L, ASN49H, ASN50H, ASP159H, ASP36L, ASP69L, GLN67L, GLU172H, GLU37H, GLU37L, GLU48H, GLU54L, GLY14H, GLY39L, HIS11H, HIS28H, ILE12H, ILE40H, ILE40L, LEU24H, LEU38L, LEU42H, LEU42L, LEU46H, LYS31H, LYS31L, LYS43H, LYS43L, LYS78L, PHE26H, PHE41H, PHE41L, PRO53L, PRO66L, SER10H, SER170H, SER30H, SER33L, SER35L, SER44H, SER44L, SER71L, THR29H, THR34L, TYR13H, TYR70L, TYR79L, VAL171H, VAL32H, VAL32L, VAL45H, VAL45L
• I-J: ALA133I, ALA133J, ALA138I, ALA138J, ALA144J, ALA149I, ALA149J, ALA158I, ALA158J, ALA160I, ALA160J, ALA166I, ALA199I, ALA199J, ALA211I, ALA211J, ARG100I, ARG100J, ARG109I, ARG109J, ARG155I, ARG155J, ARG182I, ARG182J, ARG206I, ARG206J, ASN101I, ASN101J, ASN164I, ASN164J, ASN9I, ASN9J, ASP159I, ASP159J, ASP69J, CYS137I, CYS137J, CYS200I, CYS200J, GLN189I, GLN189J, GLN205I, GLN205J, GLN232I, GLN232J, GLN67J, GLU104I, GLU104J, GLU177I, GLU177J, GLU186I, GLU186J, GLU202I, GLU202J, GLU210I, GLU210J, GLY106I, GLY106J, GLY147I, GLY147J, GLY148I, GLY148J, GLY153I, GLY153J, GLY181I, GLY181J, GLY191I, GLY191J, GLY195I, GLY195J, GLY198I, GLY198J, GLY8I, GLY8J, HIS208I, HIS208J, HIS209I, HIS209J, ILE126I, ILE126J, ILE139J, ILE150I, ILE150J, ILE185I, ILE185J, ILE188I, ILE188J, ILE204I, ILE204J, ILE207I, ILE207J, ILE97I, ILE97J, LEU146I, LEU146J, LEU151I, LEU151J, LEU154I, LEU154J, LEU156I, LEU156J, LEU161I, LEU161J, LEU168I, LEU197I, LEU197J, LEU203I, LEU203J, LYS163I, LYS163J, LYS167I, LYS175I, LYS175J, LYS201I, LYS201J, LYS231I, LYS231J, LYS98I, LYS98J, PHE136I, PHE136J, PHE212I, PHE212J, PHE229I, PHE229J, PRO102I, PRO102J, PRO152I, PRO152J, PRO169I, PRO66I, PRO66J, SER10I, SER10J, SER140J, SER157I, SER157J, SER162I, SER162J, SER178I, SER178J, SER183I, SER183J, SER187I, SER187J, SER190I, SER190J, THR132I, THR132J, THR134I, THR134J, THR135I, THR135J, THR165I, THR165J, THR176I, THR176J, THR184I, THR184J, TYR145I, TYR145J, TYR193I, TYR193J, TYR194I, TYR194J, TYR99I, TYR99J, VAL103J, VAL105I, VAL105J, VAL171I, VAL179I, VAL179J, VAL180I, VAL180J, VAL192I, VAL192J, VAL196I, VAL196J, VAL64I, VAL64J, VAL65I, VAL65J, VAL68J, VAL7J
• I-L: ARG155L, ARG25L, ARG27L, ARG47I, ARG47L, ASN49L, ASN50L, ASP159L, ASP36I, GLN67I, GLU172L, GLU37I, GLU48L, GLU54I, GLY14L, GLY39I, HIS11L, HIS28I, HIS28L, ILE12L, ILE40I, ILE40L, LEU24L, LEU38I, LEU42I, LEU42L, LEU46L, LYS31I, LYS31L, LYS43I, LYS43L, LYS78I, PHE26L, PHE41I, PHE41L, PRO53I, PRO66I, SER10L, SER162L, SER30L, SER33I, SER33L, SER35I, SER44I, SER44L, SER71I, THR29L, THR34I, TYR13L, TYR70I, TYR79I, VAL171L, VAL32I, VAL45I, VAL45L
• J-K: ARG155J, ARG25J, ARG27J, ARG47J, ARG47K, ARG73K, ASN49J, ASN50J, ASP159J, ASP36K, ASP69K, GLN67K, GLU172J, GLU37K, GLU48J, GLU54K, GLY14J, GLY39K, HIS11J, HIS28J, ILE12J, ILE173J, ILE40J, ILE40K, LEU24J, LEU38J, LEU38K, LEU42J, LEU46J, LYS31J, LYS31K, LYS43J, LYS43K, LYS78K, PHE26J, PHE41J, PHE41K, PRO53K, PRO66K, SER10J, SER30J, SER33J, SER33K, SER35K, SER44J, SER44K, SER71K, THR29J, THR34K, TYR13J, TYR70K, TYR79K, VAL171J, VAL32K, VAL45J
• K-L: ALA133K, ALA133L, ALA138K, ALA138L, ALA149K, ALA149L, ALA158K, ALA158L, ALA160K, ALA160L, ALA166K, ALA199K, ALA199L, ALA211K, ALA211L, ARG100K, ARG100L, ARG109K, ARG109L, ARG155K, ARG155L, ARG182K, ARG182L, ARG206K, ARG206L, ASN101K, ASN101L, ASN164K, ASN164L, ASN213L, ASN9K, ASN9L, ASP159K, ASP159L, CYS137K, CYS137L, CYS200K, CYS200L, GLN189K, GLN189L, GLN205K, GLN205L, GLN232K, GLN232L, GLN67L, GLU104K, GLU104L, GLU177K, GLU177L, GLU186K, GLU186L, GLU202K, GLU202L, GLU210K, GLU210L, GLY106K, GLY106L, GLY147K, GLY147L, GLY148K, GLY148L, GLY153K, GLY153L, GLY181K, GLY181L, GLY191K, GLY191L, GLY195K, GLY195L, GLY198K, GLY198L, GLY8K, GLY8L, HIS208K, HIS208L, HIS209K, HIS209L, ILE126L, ILE139K, ILE150K, ILE150L, ILE185K, ILE185L, ILE188K, ILE188L, ILE204K, ILE204L, ILE207K, ILE207L, ILE97K, ILE97L, LEU146K, LEU146L, LEU151K, LEU151L, LEU154K, LEU154L, LEU156K, LEU156L, LEU161K, LEU161L, LEU197K, LEU197L, LEU203K, LEU203L, LYS163K, LYS163L, LYS175K, LYS175L, LYS201K, LYS201L, LYS231K, LYS98K, LYS98L, PHE136K, PHE136L, PHE212K, PHE212L, PHE229K, PHE229L, PRO102K, PRO102L, PRO152K, PRO152L, PRO66K, PRO66L, SER10K, SER10L, SER157K, SER157L, SER162K, SER162L, SER178K, SER178L, SER183K, SER183L, SER187K, SER187L, SER190K, SER190L, SER30K, SER30L, THR132K, THR132L, THR134K, THR134L, THR135K, THR135L, THR165K, THR165L, THR176K, THR176L, THR184K, THR184L, TYR145K, TYR145L, TYR193K, TYR193L, TYR194K, TYR194L, TYR99K, TYR99L, VAL103L, VAL105K, VAL105L, VAL179K, VAL179L, VAL180K, VAL180L, VAL192K, VAL192L, VAL196K, VAL196L, VAL64K, VAL64L, VAL65K, VAL65L, VAL68L, VAL7L