3D87

crystal structure of interleukin-23

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 102
  • Norm. En. per Res.: -3.6027
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-41.8548	-35.3669	-290.256	-367.4776	102	29	7	11444	5	29	29
A-C	0.0	7.9894	-200.01	-192.0205	79	26	7	10129	1	14	19
A-D	0.0	0.0	-1.0355	-1.0355	6	0	0	108	0	4	2
B-C	0.0	0.0	-6.496	-6.496	16	5	0	774	0	7	4
C-D	-27.9823	-53.096	-288.42	-369.4983	113	23	7	11221	3	27	24

Interface residues

• A-B: ALA152A, ALA155A, ALA157A, ALA158A, ALA162A, ALA165A, ALA166A, ALA176B, ALA179B, ALA180B, ALA25A, ARG148A, ARG159A, ARG208B, ARG291B, ARG38A, ARG73A, ASP209B, ASP270B, ASP290B, ASP36A, ASP56A, ASP59A, CYS177B, CYS22A, CYS54A, CYS58A, CYS70A, GLN144B, GLN151A, GLN15A, GLN16A, GLN19A, GLN289B, GLN53A, GLN61A, GLU181B, GLU182B, GLU39A, GLU40A, GLY139B, GLY164A, GLY55A, GLY57A, GLY62A, GLY77A, HIS163A, HIS244B, HIS34A, HIS51A, ILE186B, ILE207B, ILE210B, ILE211B, ILE52A, ILE74A, LEU147A, LEU150A, LEU184B, LEU21A, LEU249B, LEU37A, LEU63A, LYS20A, MET35A, PHE153A, PHE161A, PHE205B, PHE206B, PHE247B, PRO178B, PRO185B, PRO243B, PRO50A, PRO60A, SER140B, SER141B, SER149A, SER175B, SER183B, SER18A, SER204B, SER241B, SER245B, SER248B, SER294B, SER295B, THR167A, THR23A, THR242B, THR250B, TRP240B, TRP26A, TYR114B, TYR246B, TYR292B, TYR293B, TYR81A, VAL154A, VAL156A, VAL160A, VAL49A
• A-C: ALA25C, ALA28A, ALA28C, ARG139A, ARG139C, ARG143A, ARG143C, ARG148A, ARG148C, ARG38A, ARG38C, ASP36A, ASP36C, GLN104C, GLN135A, GLN135C, GLN138A, GLN138C, GLN151C, GLU93A, GLU93C, GLY103C, GLY33A, GLY33C, GLY92A, GLY92C, HIS29A, HIS29C, HIS34A, HIS34C, ILE146C, ILE89C, LEU105C, LEU140A, LEU140C, LEU141A, LEU141C, LEU142A, LEU142C, LEU147C, LEU150C, LEU24C, LEU31A, LEU31C, LEU37A, LEU37C, LEU85C, LEU96A, LEU96C, LEU97A, LEU97C, LYS145A, LYS145C, MET35A, MET35C, PHE144A, PHE144C, PHE90C, PRO101A, PRO101C, PRO133A, PRO136A, PRO136C, PRO30A, PRO30C, PRO94A, PRO94C, SER100A, SER100C, SER134A, SER27C, SER95A, SER95C, TRP137A, TRP137C, TRP26C, VAL102C, VAL32A, VAL32C
• A-D: ASN103D, GLU93A, LEU97A, LYS102D, PRO101D, SER95A
• B-C: ASN103B, ASP88C, ASP99C, GLU100B, GLY86C, GLY92C, LEU96C, LEU97C, LYS102B, LYS104B, LYS99B, PRO101B, PRO98C, SER100C, SER95C, THR91C
• C-D: ALA152C, ALA155C, ALA157C, ALA158C, ALA162C, ALA165C, ALA166C, ALA176D, ALA179D, ALA180D, ALA25C, ARG148C, ARG159C, ARG208D, ARG291D, ARG38C, ARG73C, ASN103D, ASP209D, ASP270D, ASP290D, ASP36C, ASP48C, ASP56C, ASP59C, CYS177D, CYS22C, CYS54C, CYS58C, CYS70C, GLN144D, GLN151C, GLN15C, GLN16C, GLN19C, GLN289D, GLN53C, GLN61C, GLU100D, GLU181D, GLU182D, GLU44C, GLY164C, GLY55C, GLY57C, GLY62C, GLY77C, HIS163C, HIS244D, HIS29C, HIS51C, ILE211D, ILE52C, ILE74C, LEU147C, LEU150C, LEU168C, LEU184D, LEU21C, LEU249D, LEU31C, LEU37C, LEU63C, LYS102D, LYS20C, MET35C, PHE153C, PHE161C, PHE206D, PHE247D, PRO101D, PRO178D, PRO185D, PRO243D, PRO30C, PRO50C, PRO60C, SER140D, SER141D, SER149C, SER175D, SER183D, SER18C, SER203D, SER204D, SER241D, SER245D, SER248D, SER27C, SER294D, SER295D, SER296D, THR105D, THR167C, THR202D, THR23C, THR242D, THR250D, THR45C, THR46C, TRP11C, TRP240D, TRP26C, TRP297D, TYR114D, TYR246D, TYR292D, TYR293D, TYR81C, VAL154C, VAL156C, VAL160C, VAL49C