3D01

crystal structure of the protein atu1372 with unknown function from agrobacterium tumefaciens

• Total interactions analyzed: 66
• Total true interactions: 30
• Strongest Interaction:
  • Chains: B-D
  • Int. Res.: 100
  • Norm. En. per Res.: -4.4799
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-E	0.0	-23.9953	-48.1734	-72.1687	20	2	0	1544	2	2	8
A-G	0.0	0.0	-0.0004	-0.0004	2	0	0	1	0	0	1
A-I	-85.7417	-14.2197	-329.807	-429.7685	100	12	12	11992	1	9	4
A-K	-86.2713	-8.0378	-333.379	-427.6881	100	16	12	11923	1	9	4
A-L	-5.1851	-26.0607	-27.8391	-59.0849	24	4	0	1117	2	2	2
B-C	-5.4044	-28.6576	-28.4569	-62.5189	25	2	0	1135	2	2	2
B-D	-99.8815	-17.9856	-330.119	-447.9861	100	12	12	11996	1	9	4
B-F	0.0	0.0	-0.0004	-0.0004	2	0	0	1	0	0	1
B-H	-95.9508	-17.1352	-331.615	-444.7011	103	16	12	12091	1	9	4
B-J	0.0	-20.7138	-47.4651	-68.1789	20	1	0	1522	2	2	8
C-D	0.0	0.0	-0.0004	-0.0004	2	0	0	1	0	0	1
C-F	-104.6563	-14.3881	-332.867	-451.9114	101	16	12	12116	1	9	4
C-H	0.0	-18.5215	-46.4047	-64.9262	20	0	0	1503	2	2	8
C-J	-71.6994	-14.3915	-334.222	-420.3128	100	13	12	11960	1	9	4
D-F	0.0	-20.2484	-48.5977	-68.8461	20	0	0	1528	2	2	8
D-H	-95.1133	-14.5441	-336.737	-446.3944	100	12	12	12015	1	9	4
D-J	-5.2118	-26.6494	-28.3829	-60.244	24	2	0	1124	2	2	2
E-G	-76.3127	-14.9562	-337.669	-428.9379	100	12	12	12041	1	9	4
E-I	0.0	0.0	-0.0005	-0.0005	2	0	0	1	0	0	1
E-K	-2.4384	-26.1274	-27.9802	-56.546	24	3	0	1121	2	2	2
E-L	-95.1945	-14.0277	-338.13	-447.3522	102	12	12	12063	1	9	4
F-H	-5.6527	-28.3116	-28.5719	-62.5362	24	3	0	1120	2	2	2
F-J	-88.6519	-15.5375	-329.568	-433.7574	101	10	12	11958	1	9	4
G-I	-4.6668	-25.5662	-27.4913	-57.7243	24	4	0	1127	2	2	2
G-K	0.0	-22.9722	-48.7459	-71.7181	20	1	0	1530	2	2	8
G-L	-72.9125	-14.029	-331.983	-418.9244	102	11	12	12026	1	9	4
H-J	0.0	0.0	-0.0004	-0.0004	2	0	0	1	0	0	1
I-K	-75.8336	-14.2568	-326.779	-416.8694	100	11	12	11884	1	9	4
I-L	0.0	-20.5016	-48.9164	-69.418	20	0	0	1551	2	2	8
K-L	0.0	0.0	-0.0005	-0.0005	2	0	0	1	0	0	1

Interface residues

• A-E: ARG66A, ARG66E, ASP67A, ASP67E, GLU114A, GLU114E, GLY65A, GLY65E, LEU63A, LEU63E, PHE115A, PHE115E, PRO113A, PRO113E, VAL112A, VAL112E, VAL116A, VAL116E, VAL64A, VAL64E
• A-G: PRO113A, PRO113G
• A-I: ALA110A, ALA110I, ALA125I, ALA130I, ALA140I, ALA142I, ALA143I, ALA147A, ALA147I, ALA153A, ALA159A, ALA33A, ARG100I, ARG101I, ARG138I, ARG141I, ARG66A, ASN106A, ASN106I, ASN123I, ASN127I, ASN152A, ASN34A, ASN43A, ASN43I, ASP158A, GLN118I, GLN50A, GLU114I, GLU117I, GLU135I, GLU156A, GLU162I, GLY107A, GLY107I, GLY134I, GLY137I, GLY145A, GLY145I, GLY42A, GLY49A, GLY62A, HIS119I, HIS139I, ILE103I, ILE122I, ILE129I, ILE157A, ILE160A, ILE160I, ILE163I, ILE40A, LEU105I, LEU120I, LEU128I, LEU149A, LEU44A, LEU44I, LEU45A, LEU51A, LEU63A, LEU63I, LYS104I, PHE108A, PHE108I, PHE115I, PHE151A, PHE38A, PRO113A, PRO113I, PRO136I, PRO150A, PRO37A, SER111A, SER111I, SER126I, SER148A, SER148I, SER41A, SER48A, THR131I, THR39A, THR61A, TYR35A, TYR46A, TYR46I, VAL102I, VAL109A, VAL109I, VAL112A, VAL112I, VAL116I, VAL121I, VAL144A, VAL144I, VAL155A, VAL161I, VAL36A, VAL47A, VAL64I
• A-K: ALA110A, ALA110K, ALA125A, ALA130A, ALA140A, ALA142A, ALA143A, ALA147A, ALA147K, ALA153K, ALA159K, ARG100A, ARG101A, ARG138A, ARG141A, ARG66K, ASN106A, ASN106K, ASN123A, ASN127A, ASN152K, ASN34K, ASN43A, ASN43K, ASP158K, GLN118A, GLN50K, GLU114A, GLU117A, GLU135A, GLU156K, GLU162A, GLY107A, GLY107K, GLY134A, GLY137A, GLY145A, GLY145K, GLY42K, GLY49K, GLY62K, HIS119A, HIS139A, ILE103A, ILE122A, ILE129A, ILE157K, ILE160A, ILE160K, ILE163A, ILE40K, LEU105A, LEU120A, LEU128A, LEU149K, LEU44A, LEU44K, LEU45A, LEU45K, LEU51K, LEU63A, LEU63K, LYS104A, PHE108A, PHE108K, PHE115A, PHE151K, PHE38K, PRO113A, PRO113K, PRO136A, PRO150K, PRO37K, SER111A, SER111K, SER126A, SER148A, SER148K, SER41K, SER48K, THR131A, THR39K, THR61K, TYR35K, TYR46A, TYR46K, VAL102A, VAL109A, VAL109K, VAL112A, VAL112K, VAL116A, VAL121A, VAL144A, VAL144K, VAL155K, VAL161A, VAL36K, VAL47K, VAL64A
• A-L: ALA110A, ALA110L, ALA147A, ALA147L, ARG66A, ARG66L, ASN152A, ASN152L, ASP67A, ASP67L, GLY62A, GLY62L, LEU63A, LEU63L, SER148A, SER148L, THR61A, THR61L, VAL112A, VAL112L, VAL64A, VAL64L, VAL68A, VAL68L
• B-C: ALA110B, ALA110C, ALA147B, ALA147C, ARG66B, ARG66C, ASN152B, ASN152C, ASP67B, ASP67C, GLY62B, GLY62C, LEU63B, LEU63C, SER148B, SER148C, SER154C, THR61B, THR61C, VAL112B, VAL112C, VAL64B, VAL64C, VAL68B, VAL68C
• B-D: ALA110B, ALA110D, ALA125B, ALA130B, ALA140B, ALA142B, ALA143B, ALA147B, ALA147D, ALA153D, ALA159D, ALA33D, ARG100B, ARG101B, ARG138B, ARG141B, ARG66D, ASN106B, ASN106D, ASN123B, ASN127B, ASN152D, ASN34D, ASN43B, ASN43D, ASP158D, GLN118B, GLN50D, GLU114B, GLU117B, GLU135B, GLU156D, GLU162B, GLY107B, GLY107D, GLY134B, GLY137B, GLY145B, GLY145D, GLY42D, GLY49D, GLY62D, HIS119B, HIS139B, ILE103B, ILE122B, ILE129B, ILE157D, ILE160B, ILE160D, ILE163B, ILE40D, LEU105B, LEU120B, LEU128B, LEU149D, LEU44B, LEU44D, LEU45D, LEU51D, LEU63B, LEU63D, LYS104B, PHE108B, PHE108D, PHE115B, PHE151D, PHE38D, PRO113B, PRO113D, PRO136B, PRO150D, PRO37D, SER111B, SER111D, SER126B, SER148B, SER148D, SER41D, SER48D, THR131B, THR39D, THR61D, TYR35D, TYR46B, TYR46D, VAL102B, VAL109B, VAL109D, VAL112B, VAL112D, VAL116B, VAL121B, VAL144B, VAL144D, VAL155D, VAL161B, VAL36D, VAL47D, VAL64B
• B-F: PRO113B, PRO113F
• B-H: ALA110B, ALA110H, ALA125H, ALA130H, ALA140H, ALA142H, ALA143H, ALA147B, ALA147H, ALA153B, ALA159B, ALA32B, ALA33B, ARG100H, ARG101H, ARG138H, ARG141H, ARG66B, ASN106B, ASN106H, ASN123H, ASN127H, ASN152B, ASN34B, ASN43B, ASN43H, ASP158B, GLN118H, GLN50B, GLU114H, GLU117H, GLU135H, GLU156B, GLU162H, GLY107B, GLY107H, GLY134H, GLY137H, GLY145B, GLY145H, GLY42B, GLY49B, GLY62B, GLY65H, HIS119H, HIS139H, ILE103H, ILE122H, ILE129H, ILE157B, ILE160B, ILE160H, ILE163H, ILE40B, LEU105H, LEU120H, LEU128H, LEU149B, LEU44B, LEU44H, LEU45B, LEU45H, LEU51B, LEU63B, LEU63H, LYS104H, PHE108B, PHE108H, PHE115H, PHE151B, PHE38B, PRO113B, PRO113H, PRO136H, PRO150B, PRO37B, SER111B, SER111H, SER126H, SER148B, SER148H, SER41B, SER48B, THR131H, THR39B, THR61B, TYR35B, TYR46B, TYR46H, VAL102H, VAL109B, VAL109H, VAL112B, VAL112H, VAL116H, VAL121H, VAL144B, VAL144H, VAL155B, VAL161H, VAL36B, VAL47B, VAL64H
• B-J: ARG66B, ARG66J, ASP67B, ASP67J, GLU114B, GLU114J, GLY65B, GLY65J, LEU63B, LEU63J, PHE115B, PHE115J, PRO113B, PRO113J, VAL112B, VAL112J, VAL116B, VAL116J, VAL64B, VAL64J
• C-D: PRO113C, PRO113D
• C-F: ALA110C, ALA110F, ALA125C, ALA130C, ALA140C, ALA142C, ALA143C, ALA147C, ALA147F, ALA153F, ALA159F, ALA33F, ARG100C, ARG101C, ARG138C, ARG141C, ARG66F, ASN106C, ASN106F, ASN123C, ASN127C, ASN152F, ASN34F, ASN43C, ASN43F, ASP158F, GLN118C, GLN50F, GLU114C, GLU117C, GLU135C, GLU156F, GLU162C, GLY107C, GLY107F, GLY134C, GLY137C, GLY145C, GLY145F, GLY42F, GLY49F, GLY62F, HIS119C, HIS139C, ILE103C, ILE122C, ILE129C, ILE157F, ILE160C, ILE160F, ILE163C, ILE40F, LEU105C, LEU120C, LEU128C, LEU149F, LEU44C, LEU44F, LEU45C, LEU45F, LEU51F, LEU63C, LEU63F, LYS104C, PHE108C, PHE108F, PHE115C, PHE151F, PHE38F, PRO113C, PRO113F, PRO136C, PRO150F, PRO37F, SER111C, SER111F, SER126C, SER148C, SER148F, SER41F, SER48F, THR131C, THR39F, THR61F, TYR35F, TYR46C, TYR46F, VAL102C, VAL109C, VAL109F, VAL112C, VAL112F, VAL116C, VAL121C, VAL144C, VAL144F, VAL155F, VAL161C, VAL36F, VAL47F, VAL64C
• C-H: ARG66C, ARG66H, ASP67C, ASP67H, GLU114C, GLU114H, GLY65C, GLY65H, LEU63C, LEU63H, PHE115C, PHE115H, PRO113C, PRO113H, VAL112C, VAL112H, VAL116C, VAL116H, VAL64C, VAL64H
• C-J: ALA110C, ALA110J, ALA125J, ALA130J, ALA140J, ALA142J, ALA143J, ALA147C, ALA147J, ALA153C, ALA159C, ALA33C, ARG100J, ARG101J, ARG138J, ARG141J, ARG66C, ASN106C, ASN106J, ASN123J, ASN127J, ASN152C, ASN34C, ASN43C, ASN43J, ASP158C, GLN118J, GLN50C, GLU114J, GLU117J, GLU135J, GLU156C, GLU162J, GLY107C, GLY107J, GLY134J, GLY137J, GLY145C, GLY145J, GLY42C, GLY49C, GLY62C, HIS119J, HIS139J, ILE103J, ILE122J, ILE129J, ILE157C, ILE160C, ILE160J, ILE163J, ILE40C, LEU105J, LEU120J, LEU128J, LEU149C, LEU44C, LEU44J, LEU45C, LEU51C, LEU63C, LEU63J, LYS104J, PHE108C, PHE108J, PHE115J, PHE151C, PHE38C, PRO113C, PRO113J, PRO136J, PRO150C, PRO37C, SER111C, SER111J, SER126J, SER148C, SER148J, SER41C, SER48C, THR131J, THR39C, THR61C, TYR35C, TYR46C, TYR46J, VAL102J, VAL109C, VAL109J, VAL112C, VAL112J, VAL116J, VAL121J, VAL144C, VAL144J, VAL155C, VAL161J, VAL36C, VAL47C, VAL64J
• D-F: ARG66D, ARG66F, ASP67D, ASP67F, GLU114D, GLU114F, GLY65D, GLY65F, LEU63D, LEU63F, PHE115D, PHE115F, PRO113D, PRO113F, VAL112D, VAL112F, VAL116D, VAL116F, VAL64D, VAL64F
• D-H: ALA110D, ALA110H, ALA125D, ALA130D, ALA140D, ALA142D, ALA143D, ALA147D, ALA147H, ALA153H, ALA159H, ALA33H, ARG100D, ARG101D, ARG138D, ARG141D, ARG66H, ASN106D, ASN106H, ASN123D, ASN127D, ASN152H, ASN34H, ASN43D, ASN43H, ASP158H, GLN118D, GLN50H, GLU114D, GLU117D, GLU135D, GLU156H, GLU162D, GLY107D, GLY107H, GLY134D, GLY137D, GLY145D, GLY145H, GLY42H, GLY49H, GLY62H, HIS119D, HIS139D, ILE103D, ILE122D, ILE129D, ILE157H, ILE160D, ILE160H, ILE163D, ILE40H, LEU105D, LEU120D, LEU128D, LEU149H, LEU44D, LEU44H, LEU45H, LEU51H, LEU63D, LEU63H, LYS104D, PHE108D, PHE108H, PHE115D, PHE151H, PHE38H, PRO113D, PRO113H, PRO136D, PRO150H, PRO37H, SER111D, SER111H, SER126D, SER148D, SER148H, SER41H, SER48H, THR131D, THR39H, THR61H, TYR35H, TYR46D, TYR46H, VAL102D, VAL109D, VAL109H, VAL112D, VAL112H, VAL116D, VAL121D, VAL144D, VAL144H, VAL155H, VAL161D, VAL36H, VAL47H, VAL64D
• D-J: ALA110D, ALA110J, ALA147D, ALA147J, ARG66D, ARG66J, ASN152D, ASN152J, ASP67D, ASP67J, GLY62D, GLY62J, LEU63D, LEU63J, SER148D, SER148J, THR61D, THR61J, VAL112D, VAL112J, VAL64D, VAL64J, VAL68D, VAL68J
• E-G: ALA110E, ALA110G, ALA125G, ALA130G, ALA140G, ALA142G, ALA143G, ALA147E, ALA147G, ALA153E, ALA159E, ALA33E, ARG100G, ARG101G, ARG138G, ARG141G, ARG66E, ASN106E, ASN106G, ASN123G, ASN127G, ASN152E, ASN34E, ASN43E, ASN43G, ASP158E, GLN118G, GLN50E, GLU114G, GLU117G, GLU135G, GLU156E, GLU162G, GLY107E, GLY107G, GLY134G, GLY137G, GLY145E, GLY145G, GLY42E, GLY49E, GLY62E, HIS119G, HIS139G, ILE103G, ILE122G, ILE129G, ILE157E, ILE160E, ILE160G, ILE163G, ILE40E, LEU105G, LEU120G, LEU128G, LEU149E, LEU44E, LEU44G, LEU45E, LEU51E, LEU63E, LEU63G, LYS104G, PHE108E, PHE108G, PHE115G, PHE151E, PHE38E, PRO113E, PRO113G, PRO136G, PRO150E, PRO37E, SER111E, SER111G, SER126G, SER148E, SER148G, SER41E, SER48E, THR131G, THR39E, THR61E, TYR35E, TYR46E, TYR46G, VAL102G, VAL109E, VAL109G, VAL112E, VAL112G, VAL116G, VAL121G, VAL144E, VAL144G, VAL155E, VAL161G, VAL36E, VAL47E, VAL64G
• E-I: PRO113E, PRO113I
• E-K: ALA110E, ALA110K, ALA147E, ALA147K, ARG66E, ARG66K, ASN152E, ASN152K, ASP67E, ASP67K, GLY62E, GLY62K, LEU63E, LEU63K, SER148E, SER148K, THR61E, THR61K, VAL112E, VAL112K, VAL64E, VAL64K, VAL68E, VAL68K
• E-L: ALA110E, ALA110L, ALA125E, ALA130E, ALA140E, ALA142E, ALA143E, ALA147E, ALA147L, ALA153L, ALA159L, ALA32L, ALA33L, ARG100E, ARG101E, ARG138E, ARG141E, ARG66L, ASN106E, ASN106L, ASN123E, ASN127E, ASN152L, ASN34L, ASN43E, ASN43L, ASP158L, GLN118E, GLN50L, GLU114E, GLU117E, GLU135E, GLU156L, GLU162E, GLY107E, GLY107L, GLY134E, GLY137E, GLY145E, GLY145L, GLY42L, GLY49L, GLY62L, HIS119E, HIS139E, ILE103E, ILE122E, ILE129E, ILE157L, ILE160E, ILE160L, ILE163E, ILE40L, LEU105E, LEU120E, LEU128E, LEU149L, LEU44E, LEU44L, LEU45E, LEU45L, LEU51L, LEU63E, LEU63L, LYS104E, PHE108E, PHE108L, PHE115E, PHE151L, PHE38L, PRO113E, PRO113L, PRO136E, PRO150L, PRO37L, SER111E, SER111L, SER126E, SER148E, SER148L, SER41L, SER48L, THR131E, THR39L, THR61L, TYR35L, TYR46E, TYR46L, VAL102E, VAL109E, VAL109L, VAL112E, VAL112L, VAL116E, VAL121E, VAL144E, VAL144L, VAL155L, VAL161E, VAL36L, VAL47L, VAL64E
• F-H: ALA110F, ALA110H, ALA147F, ALA147H, ARG66F, ARG66H, ASN152F, ASN152H, ASP67F, ASP67H, GLY62F, GLY62H, LEU63F, LEU63H, SER148F, SER148H, THR61F, THR61H, VAL112F, VAL112H, VAL64F, VAL64H, VAL68F, VAL68H
• F-J: ALA110F, ALA110J, ALA125F, ALA130F, ALA140F, ALA142F, ALA143F, ALA147F, ALA147J, ALA153J, ALA159J, ALA33J, ARG100F, ARG101F, ARG138F, ARG141F, ARG66J, ASN106F, ASN106J, ASN123F, ASN127F, ASN152J, ASN34J, ASN43F, ASN43J, ASP158J, GLN118F, GLN50J, GLU114F, GLU117F, GLU135F, GLU156J, GLU162F, GLY107F, GLY107J, GLY134F, GLY137F, GLY145F, GLY145J, GLY42J, GLY49J, GLY62J, HIS119F, HIS139F, ILE103F, ILE122F, ILE129F, ILE157J, ILE160F, ILE160J, ILE163F, ILE40J, LEU105F, LEU120F, LEU128F, LEU149J, LEU44F, LEU44J, LEU45F, LEU45J, LEU51J, LEU63F, LEU63J, LYS104F, PHE108F, PHE108J, PHE115F, PHE151J, PHE38J, PRO113F, PRO113J, PRO136F, PRO150J, PRO37J, SER111F, SER111J, SER126F, SER148F, SER148J, SER41J, SER48J, THR131F, THR39J, THR61J, TYR35J, TYR46F, TYR46J, VAL102F, VAL109F, VAL109J, VAL112F, VAL112J, VAL116F, VAL121F, VAL144F, VAL144J, VAL155J, VAL161F, VAL36J, VAL47J, VAL64F
• G-I: ALA110G, ALA110I, ALA147G, ALA147I, ARG66G, ARG66I, ASN152G, ASN152I, ASP67G, ASP67I, GLY62G, GLY62I, LEU63G, LEU63I, SER148G, SER148I, THR61G, THR61I, VAL112G, VAL112I, VAL64G, VAL64I, VAL68G, VAL68I
• G-K: ARG66G, ARG66K, ASP67G, ASP67K, GLU114G, GLU114K, GLY65G, GLY65K, LEU63G, LEU63K, PHE115G, PHE115K, PRO113G, PRO113K, VAL112G, VAL112K, VAL116G, VAL116K, VAL64G, VAL64K
• G-L: ALA110G, ALA110L, ALA125L, ALA130L, ALA140L, ALA142L, ALA143L, ALA147G, ALA147L, ALA153G, ALA159G, ALA32G, ALA33G, ARG100L, ARG101L, ARG138L, ARG141L, ARG66G, ASN106G, ASN106L, ASN123L, ASN127L, ASN152G, ASN34G, ASN43G, ASN43L, ASP158G, GLN118L, GLN50G, GLU114L, GLU117L, GLU135L, GLU156G, GLU162L, GLY107G, GLY107L, GLY134L, GLY137L, GLY145G, GLY145L, GLY42G, GLY49G, GLY62G, HIS119L, HIS139L, ILE103L, ILE122L, ILE129L, ILE157G, ILE160G, ILE160L, ILE163L, ILE40G, LEU105L, LEU120L, LEU128L, LEU149G, LEU44G, LEU44L, LEU45G, LEU45L, LEU51G, LEU63G, LEU63L, LYS104L, PHE108G, PHE108L, PHE115L, PHE151G, PHE38G, PRO113G, PRO113L, PRO136L, PRO150G, PRO37G, SER111G, SER111L, SER126L, SER148G, SER148L, SER41G, SER48G, THR131L, THR39G, THR61G, TYR35G, TYR46G, TYR46L, VAL102L, VAL109G, VAL109L, VAL112G, VAL112L, VAL116L, VAL121L, VAL144G, VAL144L, VAL155G, VAL161L, VAL36G, VAL47G, VAL64L
• H-J: PRO113H, PRO113J
• I-K: ALA110I, ALA110K, ALA125K, ALA130K, ALA140K, ALA142K, ALA143K, ALA147I, ALA147K, ALA153I, ALA159I, ALA33I, ARG100K, ARG101K, ARG138K, ARG141K, ARG66I, ASN106I, ASN106K, ASN123K, ASN127K, ASN152I, ASN34I, ASN43I, ASN43K, ASP158I, GLN118K, GLN50I, GLU114K, GLU117K, GLU135K, GLU156I, GLU162K, GLY107I, GLY107K, GLY134K, GLY137K, GLY145I, GLY145K, GLY42I, GLY49I, GLY62I, HIS119K, HIS139K, ILE103K, ILE122K, ILE129K, ILE157I, ILE160I, ILE160K, ILE163K, ILE40I, LEU105K, LEU120K, LEU128K, LEU149I, LEU44I, LEU44K, LEU45I, LEU51I, LEU63I, LEU63K, LYS104K, PHE108I, PHE108K, PHE115K, PHE151I, PHE38I, PRO113I, PRO113K, PRO136K, PRO150I, PRO37I, SER111I, SER111K, SER126K, SER148I, SER148K, SER41I, SER48I, THR131K, THR39I, THR61I, TYR35I, TYR46I, TYR46K, VAL102K, VAL109I, VAL109K, VAL112I, VAL112K, VAL116K, VAL121K, VAL144I, VAL144K, VAL155I, VAL161K, VAL36I, VAL47I, VAL64K
• I-L: ARG66I, ARG66L, ASP67I, ASP67L, GLU114I, GLU114L, GLY65I, GLY65L, LEU63I, LEU63L, PHE115I, PHE115L, PRO113I, PRO113L, VAL112I, VAL112L, VAL116I, VAL116L, VAL64I, VAL64L
• K-L: PRO113K, PRO113L