3CO2

mlotik1 ion channel cyclic-nucleotide binding domain mutant

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 94
  • Norm. En. per Res.: -2.5421
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	0.0	-71.4266	-71.4266	41	1	4	3375	0	4	3
A-C	-4.9717	11.1834	-13.1832	-6.9715	22	0	0	508	0	7	6
A-D	-45.6834	27.0922	-188.001	-206.5923	86	7	10	8332	0	1	5
B-C	-50.3335	17.5123	-206.138	-238.9593	94	11	10	8976	0	1	5
C-D	0.0	0.0	-64.0719	-64.0719	42	2	4	3281	0	2	7

Interface residues

• A-B: ALA231A, ALA231B, ALA242A, ALA242B, ARG219B, ARG220B, ARG225A, ARG225B, ARG249A, ARG249B, ASN226A, ASP222A, ASP222B, GLN228A, GLN228B, GLN237A, GLU246A, GLU246B, GLY221A, GLY221B, GLY240A, GLY240B, LEU229A, LEU229B, LEU239A, LEU244A, LEU244B, PHE223A, PHE223B, PRO241A, PRO241B, TRP227A, TRP227B, VAL224A, VAL224B, VAL243A, VAL243B, VAL245A, VAL245B, VAL248A, VAL248B
• A-C: ARG219C, ARG220C, ARG225A, ARG225C, ASP222A, ASP222A9, ASP222C, CB9.7058434.45483, GLU277A, GLU277C, GLY221A, GLY221C, GLY278A, GLY278C, PHE223A, PHE223C, PRO292A, PRO292C, VAL224A, VAL224C, VAL276A, VAL276C
• A-D: ALA231D, ALA232A, ALA232D, ALA258A, ALA283A, ALA283D, ALA294A, ALA294D, ALA309A, ALA309D, ALA313A, ALA314A, ARG225A, ARG225D, ASN286A, ASN286D, CYS263D, GLN228D, GLN237D, GLU277A, GLU289A, GLU289D, GLU298A, GLU298D, GLY278A, GLY278D, GLY291A, GLY291D, GLY293A, GLY293D, GLY297A, GLY297D, ILE265A, LEU229A, LEU229D, LEU235D, LEU290A, LEU290D, MET272D, MET299D, PHE236D, PHE273D, PHE274D, PHE295A, PHE295D, PHE296A, PHE296D, PRO234A, PRO234D, PRO285A, PRO285D, PRO287A, PRO287D, PRO292A, PRO292D, SER279A, SER279D, SER281A, SER281D, SER308A, SER308D, SER312D, THR284A, THR284D, THR310A, THR310D, THR315A, THR316A, TRP227D, TRP307A, TRP307D, VAL230D, VAL233A, VAL233D, VAL275A, VAL275D, VAL276A, VAL280A, VAL280D, VAL282A, VAL282D, VAL288A, VAL288D, VAL311A, VAL311D, VAL317A
• B-C: ALA231B, ALA232B, ALA232C, ALA258C, ALA283B, ALA283C, ALA294B, ALA294C, ALA300B, ALA309B, ALA309C, ALA313C, ALA314C, ARG225B, ARG225C, ARG264B, ASN286B, ASN286C, CYS263B, GLN228B, GLN237B, GLU277B, GLU277C, GLU289B, GLU289C, GLU298B, GLU298C, GLY266B, GLY266C, GLY269B, GLY278B, GLY278C, GLY291B, GLY291C, GLY293B, GLY293C, GLY297B, GLY297C, ILE265B, ILE265C, LEU229B, LEU229C, LEU235B, LEU290B, LEU290C, MET272B, MET299B, MET299C, PHE236B, PHE273B, PHE274B, PHE295B, PHE295C, PHE296B, PHE296C, PRO234B, PRO234C, PRO285B, PRO285C, PRO287B, PRO287C, PRO292B, PRO292C, PRO306B, SER279B, SER279C, SER281B, SER281C, SER308B, SER308C, THR284B, THR284C, THR310B, THR310C, THR315C, THR316C, TRP227B, TRP307B, TRP307C, VAL230B, VAL233B, VAL233C, VAL275B, VAL275C, VAL276C, VAL280B, VAL280C, VAL282B, VAL282C, VAL288B, VAL288C, VAL311B, VAL311C, VAL317C
• C-D: ALA231C, ALA231D, ALA232C, ALA232D, ALA242C, ALA242D, ARG220C, ARG220D, ARG225C, ARG225D, ARG249C, ARG249D, ASN226C, ASP222D, GLN228C, GLN228D, GLN237C, GLN237D, GLU246C, GLU246D, GLY221C, GLY221D, GLY240C, GLY240D, LEU229C, LEU229D, LEU244C, LEU244D, PHE223C, PHE223D, PRO241C, PRO241D, TRP227C, TRP227D, VAL224C, VAL224D, VAL243C, VAL243D, VAL245C, VAL245D, VAL248C, VAL248D