3CK4

a heterospecific leucine zipper tetramer

• Total interactions analyzed: 66
• Total true interactions: 28
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 61
  • Norm. En. per Res.: -5.1285
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-9.1711	-54.2758	-200.525	-263.972	63	6	23	9628	4	20	19
A-C	0.0	0.0	-13.3716	-13.3716	24	0	1	1089	0	0	4
A-D	-4.2513	-7.3882	-112.657	-124.2964	58	3	18	5291	0	9	10
A-K	-9.2627	-13.5337	-20.8944	-43.6908	15	10	0	1088	2	13	9
A-L	0.0	-18.5303	-38.7574	-57.2878	34	0	0	1732	0	15	18
B-C	-19.5139	-88.4423	-204.88	-312.8361	61	4	9	8571	5	29	16
B-D	0.0	4.5304	-16.9286	-12.3982	33	0	1	1505	0	1	5
C-D	-8.7382	-39.6636	-223.423	-271.8248	66	1	29	10396	4	22	24
C-E	-6.6989	6.9055	-12.675	-12.4684	17	1	0	650	0	10	9
D-E	-12.3298	-17.8927	-56.6331	-86.8556	35	1	0	2174	1	22	23
D-H	0.0	0.0	-0.0106	-0.0106	5	0	0	10	0	0	3
D-I	0.0	0.0	-0.0025	-0.0025	2	0	0	3	0	0	0
D-L	0.0	0.0	-0.3897	-0.3897	11	0	0	85	0	2	7
E-F	-12.7809	-57.3024	-206.09	-276.1733	65	3	26	9875	5	20	20
E-G	0.0	0.0	-20.0382	-20.0382	28	2	1	1308	0	0	4
E-H	0.0	-7.7005	-63.0384	-70.7389	51	0	14	3841	0	8	6
F-G	0.0	-84.9402	-228.848	-313.7882	63	4	9	9168	4	28	16
F-H	-4.4927	0.0	-12.5315	-17.0242	25	1	1	1012	0	0	4
G-H	-6.3672	-13.9495	-193.743	-214.0596	63	3	26	9403	4	19	19
G-I	0.0	0.7382	-7.9765	-7.2383	10	0	0	337	0	5	4
H-I	-16.4057	-5.2312	-42.2772	-63.9141	25	2	0	1759	1	4	9
H-L	-9.2959	0.0	-7.0614	-16.3572	16	4	0	321	0	5	4
I-J	-34.2245	-66.8248	-214.863	-315.9123	65	5	26	10101	5	20	21
I-K	0.0	0.0	-9.0456	-9.0456	26	0	0	989	0	0	4
I-L	-6.8687	-14.0519	-114.683	-135.6036	55	4	17	5351	1	8	6
J-K	-17.6123	-99.8203	-190.877	-308.3096	61	7	9	8239	6	28	15
J-L	0.0	0.0	-14.3506	-14.3506	30	0	1	1185	0	0	4
K-L	-11.3026	-50.443	-208.671	-270.4165	64	3	26	9840	4	20	22

Interface residues

• A-B: ALA25A, ALA25B, ARG26A, ARG26B, ASN17A, ASN17B, ASN22A, ASN22B, ASP8A, ASP8B, GLN5A, GLN5B, GLU11A, GLU11B, GLU12A, GLU12B, GLU21B, GLU23A, GLU33B, GLU7B, GLY32B, HIS19A, HIS19B, LEU13A, LEU13B, LEU14A, LEU14B, LEU20A, LEU20B, LEU27A, LEU27B, LEU30A, LEU30B, LEU6A, LEU6B, LYS16A, LYS28B, LYS29A, LYS29B, LYS2A, LYS2B, LYS4A, LYS4B, LYS9A, MET1A, SER15A, SER15B, TYR18A, TYR18B, VAL10A, VAL10B, VAL16B, VAL21A, VAL23B, VAL24A, VAL24B, VAL28A, VAL31A, VAL31B, VAL3A, VAL3B, VAL7A, VAL9B
• A-C: ASN17A, GLN5C, LEU13C, LEU14A, LEU20A, LEU20C, LEU27A, LEU27C, LEU30A, LEU30C, LEU6C, LYS2C, VAL10A, VAL10C, VAL16C, VAL21A, VAL23C, VAL24A, VAL28A, VAL31A, VAL3A, VAL3C, VAL7A, VAL9C
• A-D: ALA25A, ALA25D, ARG26A, ARG26D, ARG34D, ASN17A, ASN17D, ASN22A, ASN22D, ASP8A, ASP8D, GLU11A, GLU11D, GLU12A, GLU12D, GLU23A, GLU23D, GLU33D, GLY32D, HIS19A, HIS19D, LEU13A, LEU13D, LEU14A, LEU14D, LEU20A, LEU20D, LEU27A, LEU27D, LEU30A, LEU30D, LEU6A, LEU6D, LYS16A, LYS29A, LYS29D, LYS4A, LYS4D, LYS9A, LYS9D, SER15A, SER15D, TYR18A, TYR18D, VAL10A, VAL10D, VAL21A, VAL21D, VAL24A, VAL24D, VAL28A, VAL28D, VAL31A, VAL31D, VAL3A, VAL3D, VAL7A, VAL7D
• A-K: ARG34K, ASN22A, ASP8A, GLU11A, GLU12A, GLU21K, GLU33K, HIS19A, LEU13A, LYS16A, LYS28K, LYS9A, SER15A, VAL24K, VAL31K
• A-L: ALA25A, ARG26A, ARG26L, ASN17A, ASN22A, ASN22L, ASP8A, GLN5A, GLU11A, GLU12A, GLU12L, GLU23A, GLU23L, HIS19A, HIS19L, LEU13A, LEU14A, LEU20A, LEU20L, LEU27L, LEU30L, LYS16A, LYS16L, LYS29A, LYS29L, LYS4A, LYS9A, LYS9L, SER15A, SER15L, TYR18A, TYR18L, VAL10A, VAL7A
• B-C: ALA25B, ALA25C, ARG26B, ARG26C, ASN17B, ASN17C, ASN22B, ASN22C, ASP8B, ASP8C, GLN5B, GLN5C, GLU11B, GLU11C, GLU12B, GLU12C, GLU21B, GLU21C, GLU7B, GLU7C, HIS19B, HIS19C, LEU13B, LEU13C, LEU14B, LEU14C, LEU20B, LEU20C, LEU27B, LEU27C, LEU30B, LEU30C, LEU6B, LEU6C, LYS28B, LYS28C, LYS29B, LYS29C, LYS2B, LYS2C, LYS4B, LYS4C, MET1C, SER15B, SER15C, TYR18B, TYR18C, VAL10B, VAL10C, VAL16B, VAL16C, VAL23B, VAL23C, VAL24B, VAL24C, VAL31B, VAL31C, VAL3B, VAL3C, VAL9B, VAL9C
• B-D: ALA25D, ARG34D, ASN17B, ASN17D, GLN5B, GLU33D, GLY32D, HIS19B, LEU13B, LEU14D, LEU20B, LEU20D, LEU27B, LEU27D, LEU30B, LEU30D, LEU6B, LYS29D, LYS2B, TYR18D, VAL10B, VAL10D, VAL16B, VAL21D, VAL23B, VAL24B, VAL24D, VAL28D, VAL31D, VAL3B, VAL3D, VAL7D, VAL9B
• C-D: ALA25C, ALA25D, ARG26C, ARG26D, ARG34D, ASN17C, ASN17D, ASN22C, ASN22D, ASP8C, ASP8D, GLN5C, GLN5D, GLU11C, GLU11D, GLU12C, GLU12D, GLU21C, GLU23D, GLU33C, GLU33D, GLU7C, GLY32C, GLY32D, HIS19C, HIS19D, LEU13C, LEU13D, LEU14C, LEU14D, LEU20C, LEU20D, LEU27C, LEU27D, LEU30C, LEU30D, LEU6C, LEU6D, LYS16D, LYS28C, LYS29C, LYS29D, LYS2C, LYS2D, LYS4C, LYS4D, LYS9D, MET1C, SER15C, SER15D, TYR18C, TYR18D, VAL10C, VAL10D, VAL16C, VAL21D, VAL23C, VAL24C, VAL24D, VAL28D, VAL31C, VAL31D, VAL3C, VAL3D, VAL7D, VAL9C
• C-E: ARG34C, ASN17C, ASP8E, GLU11E, GLU12E, GLU21C, GLU33C, GLY32C, HIS19E, LEU13E, LYS16E, LYS28C, LYS9E, SER15E, TYR18E, VAL24C, VAL31C
• D-E: ALA25E, ARG26D, ARG26E, ARG34D, ASN17D, ASN17E, ASN22D, ASN22E, ASP8E, GLN5E, GLU11E, GLU12D, GLU12E, GLU23D, GLU23E, GLU33D, HIS19D, HIS19E, LEU13E, LEU14E, LEU20D, LEU27D, LEU30D, LYS16D, LYS16E, LYS29D, LYS29E, LYS4E, LYS9E, SER15D, SER15E, TYR18D, TYR18E, VAL10E, VAL7E
• D-H: ASN22D, LYS29H, SER15D, TYR18D, TYR18H
• D-I: LYS29D, TYR18I
• D-L: ALA25D, ASN22D, ASN22L, HIS19L, LYS16L, LYS29D, LYS29L, SER15L, TYR18D, TYR18L, VAL21D
• E-F: ALA25E, ALA25F, ARG26E, ARG26F, ARG34F, ASN17E, ASN17F, ASN22E, ASN22F, ASP8E, ASP8F, GLN5E, GLN5F, GLU11E, GLU11F, GLU12E, GLU12F, GLU21F, GLU23E, GLU33F, GLU7F, GLY32E, GLY32F, HIS19E, HIS19F, LEU13E, LEU13F, LEU14E, LEU14F, LEU20E, LEU20F, LEU27E, LEU27F, LEU30E, LEU30F, LEU6E, LEU6F, LYS16E, LYS28F, LYS29E, LYS29F, LYS2E, LYS2F, LYS4E, LYS4F, LYS9E, MET1F, SER15E, SER15F, TYR18E, TYR18F, VAL10E, VAL10F, VAL16F, VAL21E, VAL23F, VAL24E, VAL24F, VAL28E, VAL31E, VAL31F, VAL3E, VAL3F, VAL7E, VAL9F
• E-G: ALA25E, ASN17E, ASN17G, GLN5G, GLY32E, LEU13G, LEU14E, LEU20E, LEU20G, LEU27E, LEU27G, LEU30E, LEU30G, LEU6E, LEU6G, LYS2G, VAL10E, VAL10G, VAL16G, VAL21E, VAL23G, VAL24E, VAL28E, VAL31E, VAL3E, VAL3G, VAL7E, VAL9G
• E-H: ALA25E, ALA25H, ARG26E, ARG26H, ASN17E, ASN17H, ASN22E, ASN22H, ASP8E, ASP8H, GLU11E, GLU11H, GLU12H, GLU23E, GLU23H, GLY32E, LEU13E, LEU13H, LEU14E, LEU14H, LEU20E, LEU20H, LEU27E, LEU27H, LEU30E, LEU30H, LEU6E, LEU6H, LYS29E, LYS29H, LYS4E, LYS4H, LYS9E, LYS9H, SER15E, TYR18E, TYR18H, VAL10E, VAL10H, VAL21E, VAL21H, VAL24E, VAL24H, VAL28E, VAL28H, VAL31E, VAL31H, VAL3E, VAL3H, VAL7E, VAL7H
• F-G: ALA25F, ALA25G, ARG26F, ARG26G, ASN17F, ASN17G, ASN22F, ASN22G, ASP8F, ASP8G, GLN5F, GLN5G, GLU11F, GLU11G, GLU12F, GLU12G, GLU21F, GLU21G, GLU7F, GLU7G, GLY32G, HIS19F, HIS19G, LEU13F, LEU13G, LEU14F, LEU14G, LEU20F, LEU20G, LEU27F, LEU27G, LEU30F, LEU30G, LEU6F, LEU6G, LYS28F, LYS28G, LYS29F, LYS29G, LYS2F, LYS2G, LYS4F, LYS4G, MET1F, MET1G, SER15F, SER15G, TYR18F, TYR18G, VAL10F, VAL10G, VAL16F, VAL16G, VAL23F, VAL23G, VAL24F, VAL24G, VAL31F, VAL31G, VAL3F, VAL3G, VAL9F, VAL9G
• F-H: ASN17H, GLN5F, GLU12F, LEU13F, LEU14H, LEU20F, LEU20H, LEU27F, LEU27H, LEU30F, LEU30H, LEU6F, LYS2F, VAL10F, VAL10H, VAL16F, VAL21H, VAL23F, VAL24H, VAL28H, VAL31H, VAL3F, VAL3H, VAL7H, VAL9F
• G-H: ALA25G, ALA25H, ARG26G, ARG26H, ASN17G, ASN17H, ASN22G, ASN22H, ASP8G, ASP8H, GLN5G, GLN5H, GLU11G, GLU11H, GLU12G, GLU12H, GLU21G, GLU23H, GLU33G, GLU7G, GLY32G, HIS19G, HIS19H, LEU13G, LEU13H, LEU14G, LEU14H, LEU20G, LEU20H, LEU27G, LEU27H, LEU30G, LEU30H, LEU6G, LEU6H, LYS16H, LYS28G, LYS29G, LYS29H, LYS2G, LYS2H, LYS4G, LYS4H, LYS9H, MET1G, SER15G, SER15H, TYR18G, TYR18H, VAL10G, VAL10H, VAL16G, VAL21H, VAL23G, VAL24G, VAL24H, VAL28H, VAL31G, VAL31H, VAL3G, VAL3H, VAL7H, VAL9G
• G-I: ALA25I, ARG26I, ASN22I, GLU23I, GLU33G, GLY32G, LEU30I, LYS28G, LYS29I, VAL31G
• H-I: ALA25H, ALA25I, ARG26H, ARG26I, ASN22H, ASN22I, GLU23H, GLU23I, HIS19H, HIS19I, LEU20H, LEU27H, LEU27I, LEU30H, LEU30I, LYS29H, LYS29I, TYR18H, TYR18I, VAL21H, VAL21I, VAL24H, VAL24I, VAL28H, VAL28I
• H-L: ALA25H, ARG26H, ASN22H, ASN22L, ASP8L, GLU11L, HIS19H, LEU14L, LEU30H, LYS29H, LYS4L, SER15H, SER15L, TYR18H, TYR18L, VAL7L
• I-J: ALA25I, ALA25J, ARG26I, ARG26J, ARG34J, ASN17I, ASN17J, ASN22I, ASN22J, ASP8I, ASP8J, GLN5I, GLN5J, GLU11I, GLU11J, GLU12I, GLU12J, GLU21J, GLU23I, GLU33J, GLU7J, GLY32J, HIS19I, HIS19J, LEU13I, LEU13J, LEU14I, LEU14J, LEU20I, LEU20J, LEU27I, LEU27J, LEU30I, LEU30J, LEU6I, LEU6J, LYS16I, LYS28J, LYS29I, LYS29J, LYS2I, LYS2J, LYS4I, LYS4J, LYS9I, MET1I, MET1J, SER15I, SER15J, TYR18I, TYR18J, VAL10I, VAL10J, VAL16J, VAL21I, VAL23J, VAL24I, VAL24J, VAL28I, VAL31I, VAL31J, VAL3I, VAL3J, VAL7I, VAL9J
• I-K: ALA25I, ASN17I, GLN5K, LEU13K, LEU14I, LEU20I, LEU20K, LEU27I, LEU27K, LEU30I, LEU30K, LEU6I, LEU6K, LYS2K, VAL10I, VAL10K, VAL16K, VAL21I, VAL23K, VAL24I, VAL24K, VAL28I, VAL31I, VAL3I, VAL7I, VAL9K
• I-L: ALA25I, ALA25L, ARG26I, ARG26L, ASN17I, ASN17L, ASN22I, ASN22L, ASP8I, ASP8L, GLU11I, GLU11L, GLU12I, GLU12L, GLU23I, GLU23L, HIS19I, HIS19L, LEU13I, LEU13L, LEU14I, LEU14L, LEU20I, LEU20L, LEU27I, LEU27L, LEU30I, LEU30L, LEU6I, LEU6L, LYS16I, LYS29I, LYS29L, LYS4I, LYS4L, LYS9I, LYS9L, SER15I, SER15L, TYR18I, TYR18L, VAL10I, VAL10L, VAL21I, VAL21L, VAL24I, VAL24L, VAL28I, VAL28L, VAL31I, VAL31L, VAL3I, VAL3L, VAL7I, VAL7L
• J-K: ALA25J, ALA25K, ARG26J, ARG26K, ASN17J, ASN17K, ASN22J, ASN22K, ASP8J, ASP8K, GLN5J, GLN5K, GLU11J, GLU11K, GLU12J, GLU12K, GLU21J, GLU21K, GLU7J, GLU7K, HIS19J, HIS19K, LEU13J, LEU13K, LEU14J, LEU14K, LEU20J, LEU20K, LEU27J, LEU27K, LEU30J, LEU30K, LEU6J, LEU6K, LYS28J, LYS28K, LYS29J, LYS29K, LYS2J, LYS2K, LYS4J, LYS4K, MET1J, SER15J, SER15K, TYR18J, TYR18K, VAL10J, VAL10K, VAL16J, VAL16K, VAL23J, VAL23K, VAL24J, VAL24K, VAL31J, VAL31K, VAL3J, VAL3K, VAL9J, VAL9K
• J-L: ALA25L, ASN17J, ASN17L, GLN5J, HIS19J, LEU13J, LEU14L, LEU20J, LEU20L, LEU27J, LEU27L, LEU30J, LEU30L, LEU6J, LEU6L, LYS2J, TYR18L, VAL10J, VAL10L, VAL16J, VAL21L, VAL23J, VAL24J, VAL24L, VAL28L, VAL31L, VAL3J, VAL3L, VAL7L, VAL9J
• K-L: ALA25K, ALA25L, ARG26K, ARG26L, ARG34K, ASN17K, ASN17L, ASN22K, ASN22L, ASP8K, ASP8L, GLN5K, GLN5L, GLU11K, GLU11L, GLU12K, GLU12L, GLU21K, GLU23L, GLU33K, GLU7K, GLY32K, HIS19K, HIS19L, LEU13K, LEU13L, LEU14K, LEU14L, LEU20K, LEU20L, LEU27K, LEU27L, LEU30K, LEU30L, LEU6K, LEU6L, LYS16L, LYS28K, LYS29K, LYS29L, LYS2K, LYS2L, LYS4K, LYS4L, LYS9L, MET1L, SER15K, SER15L, TYR18K, TYR18L, VAL10K, VAL10L, VAL16K, VAL21L, VAL23K, VAL24K, VAL24L, VAL28L, VAL31K, VAL31L, VAL3K, VAL3L, VAL7L, VAL9K