3CJH

tim8-tim13 complex

• Total interactions analyzed: 66
• Total true interactions: 36
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 84
  • Norm. En. per Res.: -5.6346
• Hub Node: A(8)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-48.5895	-85.6044	-322.228	-456.4219	86	18	10	13830	5	21	14
A-C	0.0	0.0	-0.1237	-0.1237	2	0	0	35	0	0	1
A-D	-10.0805	-36.4958	-214.985	-261.5613	68	18	7	9010	2	14	11
A-E	0.0	0.0	-0.1464	-0.1464	2	0	0	30	0	0	1
A-G	0.0	0.0	-2.2106	-2.2106	18	0	0	200	0	2	3
A-H	0.0	-4.0719	-47.1696	-51.2415	28	10	0	1494	0	4	6
A-J	0.0	0.0	-0.0008	-0.0008	2	0	0	2	0	0	0
A-K	0.0	0.0	-0.2259	-0.2259	4	0	0	45	0	0	0
B-E	0.0	-46.97	-186.867	-233.837	72	10	5	8848	3	14	11
B-G	-5.7683	-2.4215	-49.8373	-58.0271	27	8	0	1487	0	4	6
B-H	-2.4977	0.0	-9.1953	-11.693	10	1	0	431	0	0	1
B-J	0.0	0.0	-0.0004	-0.0004	2	0	0	1	0	1	1
C-D	-66.6453	-84.6062	-322.052	-473.3035	84	27	10	13936	6	20	14
C-E	0.0	0.0	-0.3417	-0.3417	2	0	0	48	0	0	1
C-F	-16.1673	-60.5174	-211.448	-288.1327	72	15	6	9376	6	14	11
C-I	0.0	0.0	-0.4716	-0.4716	9	0	0	102	0	0	3
C-J	-15.7591	0.8342	-39.1252	-54.0501	25	3	0	1569	1	5	4
D-G	0.0	0.0	-0.0003	-0.0003	2	0	0	1	0	0	0
D-H	0.0	0.0	-0.0003	-0.0003	2	0	0	1	0	1	1
D-I	0.0	-0.5827	-36.1663	-36.749	26	3	0	1475	1	5	4
D-J	0.0	2.9091	-9.7403	-6.8313	13	0	0	494	0	4	4
D-K	0.0	0.0	-0.0003	-0.0003	2	0	0	1	0	0	0
D-L	0.0	3.8538	-4.5849	-0.7311	12	0	0	195	0	6	2
E-F	-48.5427	-83.0619	-307.879	-439.4836	85	29	10	13882	5	20	13
E-G	0.0	0.0	-0.1506	-0.1506	4	0	0	38	0	0	0
E-J	0.0	0.0	-0.0034	-0.0034	2	0	0	2	0	0	0
F-J	0.0	2.3119	-3.4762	-1.1643	12	0	0	188	0	6	2
G-H	-38.3915	-84.1588	-325.736	-448.2862	84	20	10	13813	5	21	13
G-I	0.0	0.0	-0.131	-0.131	2	0	0	29	0	0	1
G-J	-7.7944	-40.6919	-206.767	-255.2533	70	17	7	9126	4	14	11
G-K	0.0	0.0	-0.1256	-0.1256	2	0	0	28	0	0	1
H-K	-15.3108	-51.0919	-193.235	-259.6377	71	14	5	8912	5	14	11
I-J	-50.8705	-84.7947	-321.55	-457.2151	87	21	10	13932	5	20	14
I-K	0.0	0.0	-0.2182	-0.2182	2	0	0	41	0	0	1
I-L	-15.804	-53.4959	-201.184	-270.4839	70	16	6	9348	5	14	11
K-L	-41.1921	-84.6604	-316.856	-442.7086	85	22	10	14001	5	19	13

Interface residues

• A-B: ALA46A, ALA72A, ALA79A, ALA91A, ARG71B, ARG83A, ARG95A, ASN28B, ASN42B, ASN53B, ASN56A, ASN56B, ASN67B, ASN70A, ASN70B, ASN76B, ASN86A, ASP54B, ASP74B, ASP75A, CYS44B, CYS48B, CYS57A, CYS61A, CYS64B, CYS68B, CYS73A, CYS77A, GLN31B, GLN34B, GLN39B, GLN63B, GLN76A, GLU48A, GLU50B, GLU55A, GLU59A, GLU61B, GLU62B, HIS38B, ILE37B, ILE43B, ILE53A, ILE74A, ILE77B, ILE88A, ILE93A, ILE96A, LEU49A, LEU57B, LEU65B, LEU73B, LEU78A, LYS32B, LYS46B, LYS47B, LYS52A, LYS60A, LYS80A, LYS90A, MET35B, MET82A, PHE40B, PHE45B, PHE58A, PHE72B, SER29B, SER36B, SER51B, SER55B, SER58B, SER66B, SER84A, SER89A, SER94A, THR41B, THR47A, THR75B, TRP85A, TYR81A, TYR92A, VAL33B, VAL49B, VAL52B, VAL69B, VAL87A
• A-C: ARG69A, ARG95C
• A-D: ALA46A, ALA67A, ALA72A, ALA79A, ARG69A, ARG71D, ARG78D, ASN42D, ASN51A, ASN56A, ASN67D, ASN70A, ASN70D, ASN76D, ASN81D, ASP71A, ASP74D, ASP75A, CYS44D, CYS48D, CYS57A, CYS61A, CYS64D, CYS68D, CYS73A, CYS77A, GLN39D, GLN60D, GLN63D, GLU50D, GLU55A, GLU59A, GLU61D, GLY82D, ILE43D, ILE53A, ILE74A, ILE77D, ILE79D, LEU49A, LEU62A, LEU65D, LEU73D, LEU78A, LEU83D, LYS46D, LYS47D, LYS52A, LYS60A, MET82A, PHE40D, PHE45D, PHE58A, PHE72D, PRO65A, SER54A, SER64A, SER66D, THR47A, THR63A, THR68A, THR75D, TYR66A, TYR81A, VAL49D, VAL50A, VAL69D, VAL80D
• A-E: ARG69E, ARG95A
• A-G: ASN70A, ASN70G, CYS61A, CYS61G, GLN76A, GLN76G, GLU59A, GLU59G, LEU62A, LEU62G, LYS60A, LYS60G, SER64A, SER64G, THR63A, THR63G, THR68A, THR68G
• A-H: ALA67A, ALA72A, ARG69A, ASN53H, ASN70A, ASP54H, ASP71A, ASP75A, CYS48H, CYS61A, CYS64H, CYS73A, CYS77A, GLN60H, GLN76A, GLU50H, ILE74A, LEU62A, LYS46H, LYS47H, LYS60A, SER51H, SER55H, SER58H, THR63A, THR68A, VAL49H, VAL52H
• A-J: LYS47J, THR63A
• A-K: ALA67A, SER64K, THR63K, THR68A
• B-E: ALA46E, ALA67E, ALA72E, ALA79E, ARG69E, ARG71B, ARG78B, ARG83E, ASN42B, ASN51E, ASN56E, ASN67B, ASN70B, ASN70E, ASN76B, ASN81B, ASN85B, ASP71E, ASP74B, ASP75E, CYS44B, CYS48B, CYS57E, CYS61E, CYS64B, CYS68B, CYS73E, CYS77E, GLN39B, GLN60B, GLN63B, GLN84B, GLU50B, GLU55E, GLU59E, GLU61B, GLY82B, ILE43B, ILE53E, ILE74E, ILE77B, ILE79B, LEU49E, LEU62E, LEU65B, LEU73B, LEU78E, LEU83B, LYS46B, LYS47B, LYS52E, LYS60E, MET35B, MET82E, PHE40B, PHE58E, PHE72B, PRO65E, SER54E, SER64E, SER66B, THR47E, THR63E, THR68E, THR75B, THR86B, TYR66E, TYR81E, VAL49B, VAL50E, VAL69B, VAL80B
• B-G: ALA67G, ALA72G, ARG69G, ASN53B, ASN70G, ASP54B, ASP71G, ASP75G, CYS48B, CYS61G, CYS73G, CYS77G, GLN60B, GLN76G, GLU50B, ILE74G, LEU62G, LYS46B, LYS47B, LYS60G, SER51B, SER55B, SER58B, THR63G, THR68G, VAL49B, VAL52B
• B-H: ASN53B, ASN53H, ASP54B, ASP54H, SER51B, SER51H, SER55B, SER55H, VAL52B, VAL52H
• B-J: ARG71J, GLU50B
• C-D: ALA72C, ALA79C, ALA91C, ARG71D, ARG83C, ARG95C, ASN42D, ASN53D, ASN56C, ASN56D, ASN67D, ASN70C, ASN70D, ASN76D, ASN86C, ASP54D, ASP74D, ASP75C, CYS44D, CYS48D, CYS57C, CYS61C, CYS64D, CYS68D, CYS73C, CYS77C, GLN34D, GLN39D, GLN63D, GLN76C, GLN97C, GLU48C, GLU50D, GLU55C, GLU59C, GLU61D, GLU62D, HIS38D, ILE37D, ILE43D, ILE53C, ILE74C, ILE77D, ILE88C, ILE93C, ILE96C, LEU49C, LEU57D, LEU65D, LEU73D, LEU78C, LYS32D, LYS46D, LYS47D, LYS52C, LYS60C, LYS80C, LYS90C, MET35D, MET82C, PHE40D, PHE45D, PHE58C, PHE72D, SER29D, SER36D, SER51D, SER55D, SER58D, SER66D, SER84C, SER89C, SER94C, THR41D, THR47C, THR75D, TRP85C, TYR81C, TYR92C, VAL33D, VAL49D, VAL52D, VAL69D, VAL87C
• C-E: ARG69C, ARG95E
• C-F: ALA46C, ALA67C, ALA72C, ALA79C, ARG69C, ARG71F, ARG78F, ASN42F, ASN51C, ASN56C, ASN67F, ASN70C, ASN70F, ASN76F, ASN81F, ASN85F, ASP71C, ASP74F, ASP75C, CYS44F, CYS48F, CYS57C, CYS61C, CYS64F, CYS68F, CYS73C, CYS77C, GLN39F, GLN60F, GLN63F, GLN76C, GLN84F, GLU50F, GLU55C, GLU59C, GLU61F, GLY82F, ILE43F, ILE53C, ILE74C, ILE77F, ILE79F, LEU49C, LEU62C, LEU65F, LEU73F, LEU78C, LEU83F, LYS46F, LYS47F, LYS52C, LYS60C, MET82C, PHE40F, PHE58C, PHE72F, PRO65C, SER36F, SER54C, SER64C, SER66F, THR47C, THR63C, THR68C, THR75F, THR86F, TYR66C, TYR81C, VAL49F, VAL50C, VAL69F, VAL80F
• C-I: ASN70C, ASN70I, GLN76C, GLN76I, LYS80C, LYS80I, THR63C, THR63I, THR68I
• C-J: ASN53J, ASN56C, ASN56J, ASN70C, ASP54J, CYS57C, CYS61C, CYS73C, GLU50J, GLU59C, GLU61J, LEU57J, LEU62C, LYS60C, PHE58C, PRO65C, SER51J, SER55J, SER58J, SER59J, SER64C, THR63C, THR68C, TYR66C, VAL52J
• D-G: LYS47D, THR63G
• D-H: ARG71D, GLU50H
• D-I: ASN53D, ASN56D, ASN56I, ASN70I, ASP54D, CYS57I, CYS61I, CYS73I, GLU50D, GLU59I, GLU61D, ILE74I, LEU57D, LEU62I, LYS60I, PHE58I, PRO65I, SER51D, SER55D, SER58D, SER59D, SER64I, THR63I, THR68I, TYR66I, VAL52D
• D-J: ASN53D, ASN53J, GLU50D, GLU50J, LYS46D, LYS46J, LYS47J, SER51D, SER51J, VAL49D, VAL49J, VAL52D, VAL52J
• D-K: LYS60K, SER59D
• D-L: ASN56D, CYS48L, GLN60D, GLN60L, GLU50L, GLU62D, LYS46L, LYS47L, SER51L, SER58D, SER59D, VAL49L
• E-F: ALA46E, ALA72E, ALA79E, ALA91E, ARG71F, ARG83E, ARG95E, ASN42F, ASN53F, ASN56E, ASN56F, ASN67F, ASN70E, ASN70F, ASN76F, ASN86E, ASP54F, ASP74F, ASP75E, CYS44F, CYS48F, CYS57E, CYS61E, CYS64F, CYS68F, CYS73E, CYS77E, GLN34F, GLN39F, GLN63F, GLN76E, GLN97E, GLU48E, GLU50F, GLU55E, GLU59E, GLU61F, GLU62F, HIS38F, ILE37F, ILE43F, ILE53E, ILE74E, ILE77F, ILE88E, ILE93E, ILE96E, LEU49E, LEU57F, LEU65F, LEU73F, LEU78E, LYS32F, LYS46F, LYS47F, LYS52E, LYS60E, LYS80E, LYS90E, MET35F, MET82E, PHE40F, PHE45F, PHE58E, PHE72F, SER29F, SER36F, SER51F, SER55F, SER58F, SER66F, SER84E, SER89E, SER94E, THR41F, THR47E, THR75F, TRP85E, TYR81E, TYR92E, VAL33F, VAL49F, VAL52F, VAL69F, VAL87E
• E-G: ALA67G, SER64E, THR63E, THR68G
• E-J: LYS60E, SER59J
• F-J: ASN56J, CYS48F, GLN60F, GLN60J, GLU50F, GLU62J, LYS46F, LYS47F, SER51F, SER58J, SER59J, VAL49F
• G-H: ALA46G, ALA72G, ALA79G, ALA91G, ARG71H, ARG83G, ARG95G, ASN42H, ASN53H, ASN56G, ASN56H, ASN67H, ASN70G, ASN70H, ASN76H, ASN86G, ASP54H, ASP74H, ASP75G, CYS44H, CYS48H, CYS57G, CYS61G, CYS64H, CYS68H, CYS73G, CYS77G, GLN34H, GLN39H, GLN63H, GLN76G, GLU48G, GLU50H, GLU55G, GLU59G, GLU61H, GLU62H, HIS38H, ILE37H, ILE43H, ILE53G, ILE74G, ILE77H, ILE88G, ILE93G, ILE96G, LEU49G, LEU57H, LEU65H, LEU73H, LEU78G, LYS32H, LYS46H, LYS47H, LYS52G, LYS60G, LYS80G, LYS90G, MET35H, MET82G, PHE40H, PHE45H, PHE58G, PHE72H, SER29H, SER36H, SER51H, SER55H, SER58H, SER66H, SER84G, SER89G, SER94G, THR41H, THR47G, THR75H, TRP85G, TYR81G, TYR92G, VAL33H, VAL49H, VAL52H, VAL69H, VAL87G
• G-I: ARG69G, ARG95I
• G-J: ALA46G, ALA67G, ALA72G, ALA79G, ARG69G, ARG71J, ARG78J, ASN42J, ASN51G, ASN56G, ASN67J, ASN70G, ASN70J, ASN76J, ASN81J, ASN85J, ASP71G, ASP74J, ASP75G, CYS44J, CYS48J, CYS57G, CYS61G, CYS64J, CYS68J, CYS73G, CYS77G, GLN39J, GLN60J, GLN63J, GLN76G, GLN84J, GLU50J, GLU55G, GLU59G, GLU61J, GLY82J, ILE43J, ILE53G, ILE74G, ILE77J, ILE79J, LEU49G, LEU62G, LEU65J, LEU73J, LEU78G, LEU83J, LYS46J, LYS47J, LYS52G, LYS60G, MET82G, PHE40J, PHE58G, PHE72J, PRO65G, SER54G, SER64G, SER66J, THR47G, THR63G, THR68G, THR75J, TYR66G, TYR81G, VAL49J, VAL50G, VAL69J, VAL80J
• G-K: ARG69K, ARG95G
• H-K: ALA46K, ALA67K, ALA72K, ALA79K, ARG69K, ARG71H, ARG78H, ASN42H, ASN51K, ASN56K, ASN67H, ASN70H, ASN70K, ASN76H, ASN81H, ASN85H, ASP71K, ASP74H, ASP75K, CYS44H, CYS48H, CYS57K, CYS61K, CYS64H, CYS68H, CYS73K, CYS77K, GLN39H, GLN60H, GLN63H, GLN76K, GLN84H, GLU50H, GLU55K, GLU59K, GLU61H, GLY82H, ILE43H, ILE53K, ILE74K, ILE77H, ILE79H, LEU49K, LEU62K, LEU65H, LEU73H, LEU78K, LEU83H, LYS46H, LYS47H, LYS52K, LYS60K, MET82K, PHE40H, PHE58K, PHE72H, PRO65K, SER54K, SER64K, SER66H, THR47K, THR63K, THR68K, THR75H, THR86H, TYR66K, TYR81K, VAL49H, VAL50K, VAL69H, VAL80H
• I-J: ALA72I, ALA79I, ALA91I, ALA99I, ARG71J, ARG83I, ARG95I, ASN42J, ASN53J, ASN56I, ASN56J, ASN67J, ASN70I, ASN70J, ASN76J, ASN81J, ASN86I, ASN98I, ASP54J, ASP74J, ASP75I, CYS44J, CYS48J, CYS57I, CYS61I, CYS64J, CYS68J, CYS73I, CYS77I, GLN34J, GLN39J, GLN63J, GLN76I, GLU48I, GLU50J, GLU55I, GLU59I, GLU61J, GLU62J, HIS38J, ILE37J, ILE43J, ILE53I, ILE74I, ILE77J, ILE88I, ILE93I, ILE96I, LEU49I, LEU57J, LEU65J, LEU73J, LEU78I, LYS32J, LYS46J, LYS47J, LYS52I, LYS60I, LYS80I, LYS90I, MET35J, MET82I, PHE40J, PHE45J, PHE58I, PHE72J, SER29J, SER36J, SER51J, SER55J, SER58J, SER66J, SER84I, SER89I, SER94I, THR41J, THR47I, THR75J, TRP85I, TYR81I, TYR92I, VAL33J, VAL49J, VAL52J, VAL69J, VAL80J, VAL87I
• I-K: ARG69I, ARG95K
• I-L: ALA46I, ALA67I, ALA72I, ALA79I, ARG69I, ARG71L, ARG78L, ARG83I, ASN42L, ASN51I, ASN56I, ASN67L, ASN70I, ASN70L, ASN76L, ASN81L, ASN85L, ASP71I, ASP74L, ASP75I, CYS44L, CYS48L, CYS57I, CYS61I, CYS64L, CYS68L, CYS73I, CYS77I, GLN39L, GLN60L, GLN63L, GLN76I, GLN84L, GLU55I, GLU59I, GLU61L, GLY82L, ILE43L, ILE53I, ILE74I, ILE77L, ILE79L, LEU49I, LEU62I, LEU65L, LEU73L, LEU78I, LEU83L, LYS46L, LYS47L, LYS52I, LYS60I, MET82I, PHE40L, PHE58I, PHE72L, PRO65I, SER54I, SER64I, SER66L, THR47I, THR63I, THR68I, THR75L, THR86L, TYR66I, TYR81I, VAL50I, VAL69L, VAL80L
• K-L: ALA46K, ALA72K, ALA79K, ALA91K, ARG71L, ARG78L, ARG83K, ARG95K, ASN42L, ASN53L, ASN56K, ASN56L, ASN67L, ASN70K, ASN70L, ASN76L, ASN86K, ASP54L, ASP74L, ASP75K, CYS44L, CYS48L, CYS57K, CYS61K, CYS64L, CYS68L, CYS73K, CYS77K, GLN34L, GLN39L, GLN63L, GLN76K, GLU48K, GLU50L, GLU55K, GLU59K, GLU61L, GLU62L, HIS38L, ILE37L, ILE43L, ILE53K, ILE74K, ILE77L, ILE88K, ILE93K, ILE96K, LEU49K, LEU57L, LEU65L, LEU73L, LEU78K, LYS32L, LYS46L, LYS47L, LYS52K, LYS60K, LYS80K, LYS90K, MET35L, MET82K, PHE40L, PHE45L, PHE58K, PHE72L, SER29L, SER36L, SER51L, SER55L, SER58L, SER66L, SER84K, SER89K, SER94K, THR41L, THR47K, THR75L, TRP85K, TYR81K, TYR92K, VAL33L, VAL49L, VAL52L, VAL69L, VAL87K