3CF0

structure of d2 subdomain of p97/vcp in complex with adp

• Total interactions analyzed: 91
• Total true interactions: 19
• Strongest Interaction:
  • Chains: K-L
  • Int. Res.: 141
  • Norm. En. per Res.: -2.3948
• Hub Node: C(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-3.8265	-62.2962	-239.003	-305.1257	139	7	9	11426	3	60	55
A-N	-24.7571	-58.0389	-266.356	-349.152	154	23	7	12299	3	64	58
B-C	-33.1455	-52.013	-229.292	-314.4505	153	19	5	11901	4	65	60
C-F	0.0	0.0	-0.011	-0.011	2	0	0	10	0	2	3
C-G	-14.2178	-64.5584	-255.457	-334.2332	144	11	9	11898	4	63	57
C-I	0.0	-1.0871	-11.1229	-12.21	24	0	0	1036	0	10	6
D-E	-24.4325	-39.2335	-283.14	-346.8059	156	27	9	13218	4	68	61
D-L	-14.7428	-38.9166	-226.369	-280.0284	147	13	7	11447	4	63	57
E-F	-14.362	-43.7306	-268.078	-326.1707	151	8	9	12107	2	67	56
F-I	-17.8153	-58.0986	-254.807	-330.7209	148	9	9	11975	3	67	59
G-H	-21.8124	-35.6997	-223.863	-281.3751	149	14	5	11177	4	65	57
G-I	0.0	-10.4748	-11.4595	-21.9343	23	1	0	832	0	16	12
G-J	0.0	1.0171	23.0766	24.0937	32	12	0	1975	0	15	14
H-J	0.0	0.0	-0.0736	-0.0736	5	0	0	30	0	0	1
H-M	-27.4669	-53.8021	-250.359	-331.6279	153	18	7	11993	3	65	58
I-J	-25.4306	-37.9128	-252.664	-316.0074	149	10	7	11784	3	63	58
J-K	-26.9594	-51.6505	-244.916	-323.5259	153	17	6	12109	4	67	61
K-L	-17.6993	-62.4813	-257.489	-337.6696	141	8	9	11872	4	65	57
M-N	-14.0013	-35.6702	-210.263	-259.9345	143	8	8	10711	1	61	58

Interface residues

• A-B: ALA463B, ALA557A, ALA583B, ALA585B, ALA596A, ALA597A, ALA632A, ALA667B, ALA685B, ALA694B, ALA698B, ARG465B, ARG487A, ARG560A, ARG586A, ARG586B, ARG599A, ARG625B, ARG635A, ARG638A, ARG693B, ARG700B, ARG732B, ARG744B, ASN558A, ASN602A, ASN624B, ASN660B, ASP484A, ASP501A, ASP577B, ASP580B, ASP592A, ASP592B, ASP598A, ASP609A, ASP630A, ASP640A, CYS691B, CYS695B, GLN494A, GLN603A, GLN641A, GLN692B, GLN760A, GLN763A, GLU466B, GLU488A, GLU491A, GLU498A, GLU546B, GLU554A, GLU554B, GLU556A, GLU578B, GLU607A, GLU689B, GLU701B, GLU704B, GLU706B, GLU730B, GLY507A, GLY521B, GLY544B, GLY553B, GLY587B, GLY588B, GLY591B, GLY593A, GLY594A, GLY595A, GLY610A, GLY637A, HIS499A, HIS735B, ILE582B, ILE590B, ILE601A, ILE604A, ILE699B, ILE703B, ILE707B, ILE731B, LEU464B, LEU492A, LEU504A, LEU547B, LEU548B, LEU605A, LEU634A, LEU642A, LEU661B, LEU697B, LEU762A, LYS502A, LYS505A, LYS524B, LYS543B, LYS584B, LYS663B, LYS696B, MET508A, MET550B, MET608A, MET611A, PHE503A, PHE506A, PHE552B, PHE742B, PRO496A, PRO500A, PRO510A, PRO520B, PRO545B, PRO631A, PRO636A, PRO665B, PRO729B, SER511A, SER541B, SER555A, SER581B, SER664B, SER702B, SER705B, SER746B, THR509A, THR549B, THR606A, THR623B, THR688B, THR761A, TRP551B, TYR495A, VAL468B, VAL559A, VAL600A, VAL666B, VAL728B
• A-N: ALA463A, ALA557N, ALA583A, ALA585A, ALA596N, ALA597N, ALA622A, ALA632N, ALA685A, ALA698A, ALA743A, ALA759N, ARG465A, ARG487N, ARG560N, ARG586A, ARG586N, ARG599N, ARG625A, ARG635N, ARG638N, ARG693A, ARG700A, ARG732A, ARG744A, ARG745A, ASN558N, ASN602N, ASN624A, ASN660A, ASP484N, ASP501N, ASP577A, ASP580A, ASP592A, ASP592N, ASP598N, ASP609N, ASP630N, ASP640N, CYS691A, CYS695A, GLN494N, GLN603N, GLN641N, GLN692A, GLN760N, GLN763N, GLU466A, GLU483N, GLU488N, GLU491N, GLU498N, GLU546A, GLU554A, GLU554N, GLU556N, GLU578A, GLU607N, GLU689A, GLU701A, GLU704A, GLU706A, GLU730A, GLY507N, GLY521A, GLY544A, GLY553A, GLY587A, GLY588A, GLY591A, GLY593A, GLY593N, GLY594N, GLY595N, GLY610N, GLY637N, HIS499N, HIS735A, ILE542A, ILE582A, ILE590A, ILE590N, ILE601N, ILE604N, ILE633N, ILE643N, ILE699A, ILE703A, ILE707A, ILE731A, LEU464A, LEU492N, LEU504N, LEU547A, LEU548A, LEU579A, LEU605N, LEU634N, LEU642N, LEU661A, LEU697A, LEU762N, LYS502N, LYS505N, LYS524A, LYS543A, LYS584A, LYS663A, LYS696A, MET508N, MET550A, MET608N, MET611N, PHE503N, PHE506N, PHE552A, PHE575A, PHE742A, PHE758N, PRO496N, PRO510N, PRO520A, PRO545A, PRO631N, PRO636N, PRO665A, PRO729A, SER511N, SER541A, SER555N, SER581A, SER664A, SER702A, SER746A, SER748A, THR509N, THR525A, THR549A, THR606N, THR623A, THR688A, THR761N, TRP551A, TRP551N, TYR495N, TYR517N, TYR755A, VAL468A, VAL514N, VAL559N, VAL600N, VAL666A, VAL728A
• B-C: ALA463C, ALA557B, ALA583C, ALA585C, ALA596B, ALA597B, ALA622C, ALA632B, ALA685C, ALA698C, ALA743C, ALA759B, ARG465C, ARG487B, ARG560B, ARG567B, ARG586B, ARG586C, ARG599B, ARG625C, ARG635B, ARG638B, ARG693C, ARG700C, ARG732C, ARG744C, ARG745C, ASN558B, ASN602B, ASN624C, ASN660C, ASP484B, ASP501B, ASP577C, ASP580C, ASP592B, ASP592C, ASP598B, ASP609B, ASP630B, ASP640B, CYS691C, CYS695C, GLN473C, GLN490B, GLN494B, GLN603B, GLN641B, GLN692C, GLN760B, GLN763B, GLU466C, GLU483B, GLU488B, GLU491B, GLU498B, GLU546C, GLU554B, GLU554C, GLU556B, GLU578C, GLU607B, GLU689C, GLU701C, GLU704C, GLU706C, GLU730C, GLY507B, GLY521C, GLY544C, GLY553C, GLY587C, GLY588C, GLY591C, GLY593B, GLY594B, GLY595B, GLY610B, GLY637B, HIS499B, HIS735C, ILE542C, ILE582C, ILE590C, ILE601B, ILE604B, ILE633B, ILE643B, ILE699C, ILE703C, ILE707C, ILE731C, LEU464C, LEU492B, LEU504B, LEU547C, LEU548C, LEU579C, LEU605B, LEU634B, LEU642B, LEU661C, LEU697C, LEU762B, LYS502B, LYS505B, LYS512B, LYS524C, LYS543C, LYS584C, LYS663C, LYS696C, MET508B, MET550C, MET608B, MET611B, PHE503B, PHE506B, PHE552C, PHE742C, PHE758B, PRO496B, PRO510B, PRO520C, PRO545C, PRO631B, PRO636B, PRO665C, PRO729C, SER511B, SER541C, SER581C, SER612B, SER664C, SER702C, SER746C, THR509B, THR525C, THR549C, THR606B, THR613B, THR623C, THR688C, THR761B, TRP551B, TRP551C, TYR495B, TYR517B, VAL468C, VAL559B, VAL600B, VAL666C, VAL728C
• C-F: LYS615F, PRO571C
• C-G: ALA463G, ALA557C, ALA583G, ALA585G, ALA596C, ALA597C, ALA632C, ALA667G, ALA685G, ALA694G, ALA698G, ALA759C, ARG465G, ARG487C, ARG560C, ARG586C, ARG586G, ARG599C, ARG625G, ARG635C, ARG638C, ARG693G, ARG700G, ARG732G, ARG744G, ARG745G, ASN558C, ASN602C, ASN624G, ASN660G, ASP484C, ASP501C, ASP577G, ASP580G, ASP592C, ASP592G, ASP598C, ASP609C, ASP630C, ASP640C, CYS691G, CYS695G, GLN494C, GLN603C, GLN641C, GLN692G, GLN760C, GLN763C, GLU466G, GLU488C, GLU491C, GLU498C, GLU546G, GLU554C, GLU554G, GLU556C, GLU578G, GLU607C, GLU689G, GLU701G, GLU704G, GLU706G, GLU730G, GLY507C, GLY521G, GLY544G, GLY553G, GLY587G, GLY588G, GLY591G, GLY593C, GLY594C, GLY595C, GLY610C, GLY637C, HIS499C, HIS735G, ILE582G, ILE590G, ILE601C, ILE604C, ILE699G, ILE703G, ILE707G, ILE731G, LEU464G, LEU492C, LEU504C, LEU547G, LEU548G, LEU605C, LEU634C, LEU642C, LEU661G, LEU697G, LEU762C, LYS502C, LYS505C, LYS524G, LYS543G, LYS584G, LYS663G, LYS696G, MET508C, MET550G, MET608C, MET611C, PHE503C, PHE506C, PHE552G, PHE742G, PRO496C, PRO500C, PRO510C, PRO520G, PRO545G, PRO631C, PRO636C, PRO665G, PRO729G, SER511C, SER541G, SER555C, SER581G, SER664G, SER702G, SER705G, SER746G, THR509C, THR525G, THR549G, THR606C, THR623G, THR688G, THR761C, TRP551C, TRP551G, TYR495C, TYR517C, VAL468G, VAL559C, VAL600C, VAL666G, VAL728G
• C-I: ALA569I, ALA570I, ARG560C, ARG567C, ARG567I, ASN538I, ASP564C, GLN568C, GLN568I, GLU466I, GLU470I, GLU561C, GLY610C, LYS565C, LYS565I, LYS614C, LYS615C, MET611C, PRO571I, SER612C, THR467I, VAL468I, VAL469I, VAL471I
• D-E: ALA463E, ALA557D, ALA583E, ALA585E, ALA596D, ALA597D, ALA622E, ALA632D, ALA667E, ALA685E, ALA694E, ALA698E, ALA743E, ALA759D, ARG465E, ARG487D, ARG560D, ARG586D, ARG586E, ARG599D, ARG625E, ARG635D, ARG638D, ARG662E, ARG693E, ARG700E, ARG732E, ARG744E, ARG745E, ASN558D, ASN602D, ASN624E, ASN660E, ASP484D, ASP501D, ASP577E, ASP580E, ASP592D, ASP592E, ASP598D, ASP609D, ASP630D, ASP640D, ASP686E, CYS691E, CYS695E, GLN473E, GLN490D, GLN494D, GLN603D, GLN641D, GLN692E, GLN760D, GLN763D, GLU466E, GLU483D, GLU488D, GLU491D, GLU498D, GLU546E, GLU554D, GLU554E, GLU556D, GLU578E, GLU607D, GLU689E, GLU701E, GLU704E, GLU706E, GLU730E, GLY507D, GLY521E, GLY544E, GLY553E, GLY587E, GLY588E, GLY591E, GLY593D, GLY594D, GLY595D, GLY610D, GLY637D, HIS499D, HIS735E, ILE542E, ILE582E, ILE590E, ILE601D, ILE604D, ILE633D, ILE643D, ILE699E, ILE703E, ILE707E, ILE731E, LEU464E, LEU492D, LEU504D, LEU547E, LEU548E, LEU579E, LEU605D, LEU634D, LEU642D, LEU661E, LEU697E, LEU762D, LYS502D, LYS505D, LYS512D, LYS524E, LYS543E, LYS584E, LYS663E, LYS696E, MET508D, MET550E, MET608D, MET611D, PHE503D, PHE506D, PHE552E, PHE742E, PRO496D, PRO500D, PRO510D, PRO520E, PRO545E, PRO631D, PRO636D, PRO665E, PRO729E, SER511D, SER541E, SER555D, SER581E, SER664E, SER702E, SER746E, THR509D, THR549E, THR606D, THR613D, THR623E, THR688E, THR761D, TRP551D, TRP551E, TYR495D, TYR517D, VAL468E, VAL514D, VAL559D, VAL600D, VAL666E, VAL728E
• D-L: ALA463D, ALA557L, ALA583D, ALA585D, ALA596L, ALA597L, ALA622D, ALA632L, ALA685D, ALA698D, ALA743D, ALA759L, ARG465D, ARG487L, ARG560L, ARG567L, ARG586D, ARG586L, ARG599L, ARG625D, ARG635L, ARG638L, ARG693D, ARG700D, ARG732D, ARG744D, ARG745D, ASN558L, ASN602L, ASN624D, ASN660D, ASP484L, ASP501L, ASP577D, ASP580D, ASP592D, ASP592L, ASP598L, ASP609L, ASP630L, ASP640L, CYS691D, CYS695D, GLN494L, GLN603L, GLN641L, GLN692D, GLN760L, GLN763L, GLU466D, GLU483L, GLU488L, GLU491L, GLU498L, GLU546D, GLU554D, GLU554L, GLU556L, GLU578D, GLU607L, GLU689D, GLU701D, GLU704D, GLU706D, GLU730D, GLY507L, GLY521D, GLY544D, GLY553D, GLY587D, GLY588D, GLY591D, GLY593L, GLY594L, GLY595L, GLY610L, GLY637L, HIS499L, HIS735D, ILE542D, ILE582D, ILE590D, ILE601L, ILE604L, ILE633L, ILE699D, ILE703D, ILE707D, ILE731D, LEU464D, LEU492L, LEU504L, LEU547D, LEU548D, LEU579D, LEU605L, LEU634L, LEU642L, LEU661D, LEU697D, LEU762L, LYS502L, LYS505L, LYS512L, LYS524D, LYS543D, LYS584D, LYS663D, LYS696D, MET508L, MET550D, MET608L, MET611L, PHE503L, PHE506L, PHE552D, PHE742D, PRO496L, PRO510L, PRO520D, PRO545D, PRO631L, PRO636L, PRO665D, PRO729D, SER511L, SER541D, SER581D, SER612L, SER664D, SER702D, SER746D, THR509L, THR549D, THR606L, THR623D, THR688D, THR761L, TRP551D, TRP551L, TYR495L, TYR517L, VAL468D, VAL559L, VAL600L, VAL666D, VAL728D
• E-F: ALA463F, ALA557E, ALA583F, ALA585F, ALA596E, ALA597E, ALA622F, ALA632E, ALA667F, ALA685F, ALA694F, ALA698F, ALA759E, ARG465F, ARG487E, ARG560E, ARG586E, ARG586F, ARG599E, ARG625F, ARG635E, ARG638E, ARG693F, ARG700F, ARG732F, ARG744F, ARG745F, ASN558E, ASN602E, ASN624F, ASN660F, ASP484E, ASP501E, ASP577F, ASP580F, ASP592E, ASP592F, ASP598E, ASP609E, ASP630E, ASP640E, CYS691F, CYS695F, GLN473F, GLN490E, GLN494E, GLN603E, GLN641E, GLN692F, GLN760E, GLN763E, GLU466F, GLU483E, GLU488E, GLU491E, GLU498E, GLU546F, GLU554E, GLU554F, GLU556E, GLU578F, GLU607E, GLU689F, GLU701F, GLU704F, GLU706F, GLU730F, GLY507E, GLY521F, GLY544F, GLY553F, GLY587F, GLY588F, GLY591F, GLY593E, GLY594E, GLY595E, GLY610E, GLY637E, HIS499E, HIS735F, ILE542F, ILE582F, ILE590F, ILE601E, ILE604E, ILE633E, ILE699F, ILE703F, ILE707F, ILE731F, LEU464F, LEU492E, LEU504E, LEU547F, LEU548F, LEU579F, LEU605E, LEU634E, LEU642E, LEU661F, LEU697F, LEU762E, LYS502E, LYS505E, LYS524F, LYS543F, LYS584F, LYS663F, LYS696F, MET508E, MET550F, MET608E, MET611E, PHE503E, PHE506E, PHE552F, PHE742F, PRO496E, PRO500E, PRO510E, PRO520F, PRO545F, PRO631E, PRO636E, PRO665F, PRO729F, SER511E, SER541F, SER555E, SER581F, SER664F, SER702F, SER705F, SER746F, THR509E, THR549F, THR606E, THR613E, THR623F, THR688F, THR761E, TRP551E, TRP551F, TYR495E, VAL468F, VAL514E, VAL559E, VAL600E, VAL666F, VAL728F
• F-I: ALA463I, ALA557F, ALA583I, ALA585I, ALA596F, ALA597F, ALA632F, ALA667I, ALA685I, ALA694I, ALA698I, ALA743I, ALA759F, ARG465I, ARG487F, ARG560F, ARG586F, ARG586I, ARG599F, ARG625I, ARG635F, ARG638F, ARG693I, ARG700I, ARG732I, ARG744I, ARG745I, ASN558F, ASN602F, ASN624I, ASN660I, ASP484F, ASP501F, ASP577I, ASP580I, ASP592F, ASP592I, ASP598F, ASP609F, ASP630F, ASP640F, ASP686I, CYS691I, CYS695I, GLN494F, GLN603F, GLN641F, GLN692I, GLN760F, GLN763F, GLU466I, GLU488F, GLU491F, GLU498F, GLU546I, GLU554F, GLU554I, GLU556F, GLU578I, GLU607F, GLU689I, GLU701I, GLU704I, GLU706I, GLU730I, GLY507F, GLY521I, GLY544I, GLY553I, GLY587I, GLY588I, GLY591I, GLY593F, GLY594F, GLY595F, GLY610F, GLY637F, HIS499F, HIS735I, ILE542I, ILE582I, ILE590I, ILE601F, ILE604F, ILE699I, ILE703I, ILE707I, ILE731I, LEU464I, LEU492F, LEU504F, LEU547I, LEU548I, LEU605F, LEU634F, LEU642F, LEU661I, LEU697I, LEU762F, LYS502F, LYS505F, LYS524I, LYS543I, LYS584I, LYS663I, LYS696I, MET508F, MET550I, MET608F, MET611F, PHE503F, PHE506F, PHE552I, PHE742I, PRO496F, PRO500F, PRO510F, PRO520I, PRO545I, PRO631F, PRO636F, PRO665I, PRO729I, SER511F, SER541I, SER555F, SER581I, SER664I, SER683I, SER702I, SER746I, THR509F, THR525I, THR549I, THR606F, THR623I, THR688I, THR761F, TRP551F, TRP551I, TYR495F, TYR755I, VAL468I, VAL514F, VAL559F, VAL600F, VAL666I, VAL728I
• G-H: ALA463H, ALA557G, ALA583H, ALA585H, ALA596G, ALA597G, ALA622H, ALA632G, ALA685H, ALA698H, ALA743H, ALA759G, ARG465H, ARG487G, ARG560G, ARG567G, ARG586G, ARG586H, ARG599G, ARG625H, ARG635G, ARG638G, ARG693H, ARG700H, ARG744H, ARG745H, ASN558G, ASN602G, ASN624H, ASN660H, ASP484G, ASP577H, ASP580H, ASP592G, ASP592H, ASP598G, ASP609G, ASP630G, ASP640G, CYS691H, CYS695H, GLN473H, GLN490G, GLN494G, GLN603G, GLN641G, GLN692H, GLN760G, GLN763G, GLU466H, GLU483G, GLU488G, GLU491G, GLU498G, GLU546H, GLU554G, GLU554H, GLU556G, GLU578H, GLU607G, GLU689H, GLU701H, GLU704H, GLU706H, GLU730H, GLY507G, GLY521H, GLY544H, GLY553H, GLY587H, GLY588H, GLY591H, GLY593G, GLY594G, GLY595G, GLY610G, GLY637G, HIS499G, ILE542H, ILE582H, ILE590H, ILE601G, ILE604G, ILE633G, ILE643G, ILE699H, ILE703H, ILE707H, ILE731H, LEU464H, LEU492G, LEU504G, LEU547H, LEU548H, LEU579H, LEU605G, LEU634G, LEU642G, LEU661H, LEU697H, LEU762G, LYS502G, LYS505G, LYS512G, LYS524H, LYS543H, LYS584H, LYS663H, LYS696H, MET508G, MET550H, MET608G, MET611G, PHE503G, PHE506G, PHE552H, PHE742H, PHE758G, PRO496G, PRO510G, PRO520H, PRO545H, PRO631G, PRO636G, PRO665H, PRO729H, SER511G, SER541H, SER581H, SER612G, SER664H, SER702H, THR509G, THR525H, THR549H, THR606G, THR613G, THR623H, THR688H, THR761G, TRP551H, TYR495G, TYR517G, VAL468H, VAL514G, VAL559G, VAL600G, VAL666H, VAL728H
• G-I: ALA566I, ALA569G, ALA569I, ALA570I, ARG465G, ARG560I, ARG567I, ASN538G, ASN616I, ASP564I, GLN568G, GLN568I, GLU466G, GLU561G, GLY610I, LYS565G, LYS565I, LYS615I, MET611I, SER612I, THR467G, VAL468G, VAL469G
• G-J: ALA566G, ALA569G, ALA569J, ALA570G, ARG465J, ARG560G, ARG567G, ARG567J, ASN538G, ASN538J, ASN616G, ASP564G, ASP564J, CYS572G, GLN568G, GLN568J, GLU466J, GLU561J, ILE540J, LYS565G, LYS565J, LYS614G, LYS615G, PRO571G, SER612G, THR467J, THR613G, VAL468J, VAL469G, VAL469J, VAL471J, VAL617G
• H-J: GLN536J, GLN568H, GLU466H, LYS565H, VAL471J
• H-M: ALA463M, ALA557H, ALA583M, ALA585M, ALA596H, ALA597H, ALA622M, ALA632H, ALA685M, ALA698M, ALA743M, ALA759H, ARG465M, ARG487H, ARG560H, ARG567H, ARG586H, ARG586M, ARG599H, ARG625M, ARG635H, ARG638H, ARG693M, ARG700M, ARG732M, ARG744M, ARG745M, ASN558H, ASN602H, ASN624M, ASN660M, ASP484H, ASP501H, ASP577M, ASP580M, ASP592H, ASP592M, ASP598H, ASP609H, ASP630H, ASP640H, CYS691M, CYS695M, GLN473M, GLN494H, GLN603H, GLN641H, GLN692M, GLN760H, GLN763H, GLU466M, GLU483H, GLU488H, GLU491H, GLU498H, GLU546M, GLU554H, GLU554M, GLU556H, GLU578M, GLU607H, GLU689M, GLU701M, GLU704M, GLU706M, GLU730M, GLY507H, GLY521M, GLY544M, GLY553M, GLY587M, GLY588M, GLY591M, GLY593H, GLY594H, GLY595H, GLY610H, GLY637H, HIS499H, HIS735M, ILE542M, ILE582M, ILE590M, ILE601H, ILE604H, ILE633H, ILE643H, ILE699M, ILE703M, ILE707M, ILE731M, LEU464M, LEU492H, LEU504H, LEU547M, LEU548M, LEU579M, LEU605H, LEU634H, LEU642H, LEU661M, LEU697M, LEU762H, LYS502H, LYS505H, LYS512H, LYS524M, LYS543M, LYS584M, LYS663M, LYS696M, MET508H, MET550M, MET608H, MET611H, PHE503H, PHE506H, PHE552M, PHE742M, PHE758H, PRO496H, PRO510H, PRO520M, PRO545M, PRO631H, PRO636H, PRO665M, PRO729M, SER511H, SER541M, SER555H, SER581M, SER612H, SER664M, SER702M, SER746M, THR509H, THR525M, THR549M, THR606H, THR613H, THR623M, THR688M, THR761H, TRP551H, TRP551M, TYR495H, TYR517H, VAL468M, VAL559H, VAL600H, VAL666M, VAL728M
• I-J: ALA463J, ALA557I, ALA583J, ALA585J, ALA596I, ALA597I, ALA622J, ALA632I, ALA685J, ALA698J, ALA743J, ALA759I, ARG465J, ARG487I, ARG560I, ARG567I, ARG586I, ARG586J, ARG599I, ARG625J, ARG635I, ARG638I, ARG693J, ARG700J, ARG732J, ARG744J, ARG745J, ASN558I, ASN602I, ASN624J, ASN660J, ASP484I, ASP501I, ASP577J, ASP580J, ASP592I, ASP592J, ASP598I, ASP609I, ASP630I, ASP640I, CYS691J, CYS695J, GLN473J, GLN494I, GLN603I, GLN641I, GLN692J, GLN760I, GLN763I, GLU466J, GLU488I, GLU491I, GLU498I, GLU546J, GLU554I, GLU554J, GLU556I, GLU578J, GLU607I, GLU689J, GLU701J, GLU704J, GLU706J, GLU730J, GLY507I, GLY521J, GLY544J, GLY553J, GLY587J, GLY588J, GLY591J, GLY593I, GLY594I, GLY595I, GLY610I, GLY637I, HIS499I, HIS735J, ILE542J, ILE582J, ILE590J, ILE601I, ILE604I, ILE633I, ILE699J, ILE703J, ILE707J, ILE731J, LEU464J, LEU492I, LEU504I, LEU547J, LEU548J, LEU579J, LEU605I, LEU634I, LEU642I, LEU661J, LEU697J, LEU762I, LYS502I, LYS505I, LYS512I, LYS524J, LYS543J, LYS584J, LYS663J, LYS696J, MET508I, MET550J, MET608I, MET611I, PHE503I, PHE506I, PHE552J, PHE742J, PRO496I, PRO510I, PRO520J, PRO545J, PRO631I, PRO636I, PRO665J, PRO729J, SER511I, SER541J, SER555I, SER581J, SER612I, SER664J, SER702J, SER746J, THR509I, THR549J, THR606I, THR613I, THR623J, THR688J, THR761I, TRP551I, TRP551J, TYR495I, TYR755J, VAL468J, VAL559I, VAL600I, VAL666J, VAL728J
• J-K: ALA463K, ALA557J, ALA583K, ALA585K, ALA596J, ALA597J, ALA622K, ALA632J, ALA667K, ALA685K, ALA698K, ALA743K, ALA759J, ARG465K, ARG487J, ARG560J, ARG567J, ARG586J, ARG586K, ARG599J, ARG625K, ARG635J, ARG638J, ARG693K, ARG700K, ARG732K, ARG744K, ARG745K, ASN558J, ASN602J, ASN624K, ASN660K, ASP484J, ASP501J, ASP577K, ASP580K, ASP592J, ASP592K, ASP598J, ASP609J, ASP630J, ASP640J, CYS691K, CYS695K, GLN473K, GLN490J, GLN494J, GLN603J, GLN641J, GLN692K, GLN760J, GLN763J, GLU466K, GLU483J, GLU488J, GLU491J, GLU498J, GLU546K, GLU554J, GLU554K, GLU556J, GLU578K, GLU607J, GLU689K, GLU701K, GLU704K, GLU706K, GLU730K, GLY507J, GLY521K, GLY544K, GLY553K, GLY587K, GLY588K, GLY591K, GLY593J, GLY594J, GLY595J, GLY610J, GLY637J, HIS499J, HIS735K, ILE542K, ILE582K, ILE590K, ILE601J, ILE604J, ILE633J, ILE699K, ILE703K, ILE707K, ILE731K, LEU464K, LEU492J, LEU504J, LEU547K, LEU548K, LEU579K, LEU605J, LEU634J, LEU642J, LEU661K, LEU697K, LEU762J, LYS502J, LYS505J, LYS512J, LYS524K, LYS543K, LYS584K, LYS663K, LYS696K, MET508J, MET550K, MET608J, MET611J, PHE503J, PHE506J, PHE552K, PHE742K, PRO496J, PRO510J, PRO520K, PRO545K, PRO631J, PRO636J, PRO665K, PRO729K, SER511J, SER541K, SER581K, SER612J, SER664K, SER702K, SER746K, THR509J, THR525K, THR549K, THR606J, THR613J, THR623K, THR688K, THR761J, TRP551J, TRP551K, TYR495J, TYR517J, TYR755K, VAL468K, VAL559J, VAL600J, VAL666K, VAL728K
• K-L: ALA463L, ALA557K, ALA583L, ALA585L, ALA596K, ALA597K, ALA632K, ALA667L, ALA685L, ALA694L, ALA698L, ALA743L, ALA759K, ARG465L, ARG487K, ARG560K, ARG586K, ARG586L, ARG599K, ARG625L, ARG635K, ARG638K, ARG693L, ARG700L, ARG732L, ARG744L, ARG745L, ASN558K, ASN602K, ASN624L, ASN660L, ASP484K, ASP501K, ASP577L, ASP580L, ASP592K, ASP592L, ASP598K, ASP609K, ASP630K, ASP640K, CYS691L, CYS695L, GLN494K, GLN603K, GLN641K, GLN692L, GLN760K, GLN763K, GLU466L, GLU488K, GLU491K, GLU498K, GLU546L, GLU554K, GLU554L, GLU556K, GLU578L, GLU607K, GLU689L, GLU701L, GLU704L, GLU706L, GLU730L, GLY507K, GLY521L, GLY544L, GLY553L, GLY587L, GLY588L, GLY591L, GLY593K, GLY594K, GLY595K, GLY610K, GLY637K, HIS499K, HIS735L, ILE582L, ILE590L, ILE601K, ILE604K, ILE699L, ILE703L, ILE707L, ILE731L, LEU464L, LEU492K, LEU504K, LEU547L, LEU548L, LEU605K, LEU634K, LEU642K, LEU661L, LEU697L, LEU762K, LYS502K, LYS505K, LYS524L, LYS543L, LYS584L, LYS663L, LYS696L, MET508K, MET550L, MET608K, MET611K, PHE503K, PHE506K, PHE552L, PHE742L, PRO496K, PRO500K, PRO510K, PRO520L, PRO545L, PRO631K, PRO636K, PRO665L, PRO729L, SER511K, SER555K, SER581L, SER664L, SER702L, SER746L, THR509K, THR549L, THR606K, THR623L, THR688L, THR761K, TRP551K, TRP551L, TYR495K, VAL468L, VAL559K, VAL600K, VAL666L, VAL728L
• M-N: ALA463N, ALA557M, ALA583N, ALA585N, ALA596M, ALA597M, ALA632M, ALA685N, ALA698N, ALA743N, ALA759M, ARG465N, ARG487M, ARG560M, ARG586M, ARG586N, ARG599M, ARG625N, ARG635M, ARG638M, ARG693N, ARG700N, ARG732N, ARG744N, ARG745N, ASN558M, ASN602M, ASN624N, ASN660N, ASP484M, ASP501M, ASP577N, ASP580N, ASP592M, ASP592N, ASP598M, ASP609M, ASP630M, ASP640M, CYS691N, CYS695N, GLN490M, GLN494M, GLN603M, GLN641M, GLN692N, GLN760M, GLN763M, GLU466N, GLU483M, GLU488M, GLU491M, GLU498M, GLU546N, GLU554M, GLU554N, GLU556M, GLU578N, GLU607M, GLU689N, GLU701N, GLU704N, GLU706N, GLU730N, GLY507M, GLY521N, GLY544N, GLY553N, GLY587N, GLY588N, GLY591N, GLY593M, GLY594M, GLY595M, GLY610M, GLY637M, HIS499M, HIS735N, ILE582N, ILE590N, ILE601M, ILE604M, ILE643M, ILE699N, ILE703N, ILE707N, ILE731N, LEU464N, LEU492M, LEU504M, LEU547N, LEU548N, LEU605M, LEU634M, LEU642M, LEU661N, LEU697N, LEU762M, LYS502M, LYS505M, LYS524N, LYS543N, LYS584N, LYS663N, LYS696N, MET508M, MET550N, MET608M, MET611M, PHE503M, PHE506M, PHE552N, PHE742N, PRO496M, PRO510M, PRO520N, PRO545N, PRO631M, PRO636M, PRO665N, PRO729N, SER511M, SER541N, SER555M, SER581N, SER664N, SER702N, SER746N, THR509M, THR525N, THR549N, THR606M, THR623N, THR688N, THR761M, TRP551N, TYR495M, VAL468N, VAL514M, VAL559M, VAL600M, VAL666N, VAL728N