3CAE

structure of nnqqny as an insert in t7 endonuclease i

• Total interactions analyzed: 45
• Total true interactions: 28
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 190
  • Norm. En. per Res.: -7.6288
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-401.521	15.9103	-1063.86	-1449.4707	190	81	36	39485	5	57	58
A-C	0.0	65.038	-83.4186	-18.3806	58	10	1	4234	0	27	23
A-D	0.0	0.0	-0.0778	-0.0778	4	0	0	29	0	0	2
A-I	0.0	13.3279	-53.1167	-39.7888	46	4	0	2815	0	20	22
A-J	0.0	-3.7893	-92.9056	-96.6949	60	5	0	4383	1	27	18
B-C	0.0	0.4353	-86.9067	-86.4714	54	4	0	3898	0	26	18
B-D	-2.655	14.3087	-48.1975	-36.5438	47	7	0	2645	0	15	20
B-I	0.0	0.0	-0.3215	-0.3215	4	0	0	73	0	0	3
B-J	0.0	33.2411	-95.648	-62.4069	64	4	1	4613	0	29	23
C-D	-376.4352	51.8382	-1087.38	-1411.977	186	83	37	39194	1	57	57
C-E	0.0	6.2193	-82.342	-76.1227	56	9	0	3015	0	22	22
C-I	0.0	0.0	-23.8524	-23.8524	20	1	0	981	0	5	5
D-E	0.0	2.8865	-85.7904	-82.9039	56	1	0	4037	0	26	18
D-F	0.0	6.1522	-81.9936	-75.8414	56	9	0	2977	0	22	22
D-J	0.0	0.0	-0.0454	-0.0454	3	0	0	19	0	0	0
E-F	-360.6223	53.6219	-1102.64	-1409.6404	187	84	37	39457	1	57	58
E-G	0.0	14.3521	-48.0544	-33.7023	47	10	0	2698	0	15	20
E-H	0.0	0.0	-0.0781	-0.0781	4	0	0	29	0	0	2
E-I	0.0	0.0	-0.0473	-0.0473	3	0	0	21	0	0	0
F-G	0.0	0.4643	-89.9076	-89.4433	54	8	0	3985	0	26	18
F-H	0.0	65.1366	-84.2875	-19.1509	59	9	1	4170	0	27	23
F-J	0.0	0.0	-23.6654	-23.6654	20	1	0	966	0	5	5
G-H	-390.8351	16.9671	-1067.44	-1441.308	189	86	36	39731	5	57	58
G-I	0.0	33.2031	-96.143	-62.9399	64	2	1	4581	0	29	23
G-J	0.0	0.0	-0.3257	-0.3257	4	0	0	72	0	0	3
H-I	0.0	-3.8732	-93.5806	-97.4538	60	9	0	4379	1	27	18
H-J	0.0	13.578	-55.5659	-41.9879	46	3	0	2801	0	20	22
I-J	-353.414	41.4576	-1058.19	-1370.1464	185	78	34	38408	4	56	56

Interface residues

• A-B: ALA124A, ALA124B, ALA130A, ALA130B, ARG144A, ARG144B, ARG147A, ARG147B, ARG85A, ARG85B, ASN45A, ASN45B, ASN46A, ASN46B, ASN49A, ASN49B, ASN63A, ASN63B, ASP125A, ASP125B, ASP143A, ASP143B, ASP21A, ASP21B, ASP58A, ASP58B, ASP76A, ASP76B, ASP77A, ASP92A, GLN26A, GLN26B, GLN47A, GLN47B, GLN48A, GLN48B, GLN87A, GLN87B, GLU131A, GLU131B, GLU20A, GLU20B, GLU28A, GLU28B, GLU35A, GLU35B, GLU37A, GLU37B, GLU38A, GLU38B, GLU68A, GLU68B, GLU86A, GLU86B, GLU90A, GLU90B, GLY18A, GLY18B, GLY31A, GLY31B, GLY64A, GLY64B, GLY71A, GLY71B, HIS53A, HIS53B, HIS81A, HIS81B, HIS88A, HIS88B, ILE128A, ILE128B, ILE133A, ILE133B, ILE32A, ILE32B, ILE65A, ILE65B, ILE84A, ILE84B, ILE93A, ILE93B, ILE95A, ILE95B, LEU127A, LEU127B, LEU145A, LEU145B, LEU19A, LEU19B, LEU27A, LEU27B, LEU60A, LEU60B, LEU61A, LEU61B, LEU72A, LEU72B, LEU83A, LEU83B, LEU91A, LEU91B, LYS126A, LYS126B, LYS134A, LYS134B, LYS146A, LYS146B, LYS148A, LYS148B, LYS22A, LYS22B, LYS25A, LYS25B, LYS30A, LYS30B, LYS33A, LYS33B, LYS40A, LYS40B, LYS70A, LYS70B, LYS79A, LYS79B, LYS80A, LYS80B, MET17A, MET17B, PHE142A, PHE142B, PHE34A, PHE34B, PHE59A, PHE59B, PHE66A, PHE66B, PHE97A, PHE97B, PRO129A, PRO129B, PRO141A, PRO141B, PRO42A, PRO42B, PRO57A, PRO57B, PRO62A, PRO62B, SER24A, SER24B, SER29A, SER29B, SER44A, SER44B, SER51A, SER51B, SER52A, SER52B, SER98A, SER98B, SER99A, SER99B, THR54A, THR54B, THR56A, THR56B, THR69A, THR69B, TRP132A, TRP132B, TRP39A, TRP39B, TYR36A, TYR36B, TYR43A, TYR43B, TYR50A, TYR50B, TYR55A, TYR55B, VAL140A, VAL140B, VAL23A, VAL23B, VAL41A, VAL41B, VAL67A, VAL67B, VAL96A, VAL96B
• A-C: ALA124C, ALA130C, ARG101C, ARG144C, ARG78A, ARG94C, ASN45A, ASN46A, ASP125C, ASP143C, ASP76A, ASP77A, GLN87C, GLU114C, GLU117C, GLU131C, GLU135C, GLU74A, GLU90C, GLY107A, GLY113C, GLY120C, HIS119A, HIS88C, ILE128C, LEU104A, LEU127C, LEU72A, LEU91C, LYS103A, LYS106A, LYS118A, LYS118C, LYS122C, LYS126C, LYS134C, LYS79A, PHE115A, PHE123C, PRO109A, PRO129C, PRO136C, PRO141C, PRO42A, PRO89C, SER100C, SER108A, SER111C, SER44A, SER75A, SER99C, THR110A, TRP132C, TRP73A, TYR105A, TYR43A, VAL41A, VAL96C
• A-D: GLN26D, LYS106A, LYS22D, LYS30D
• A-I: ARG101A, ARG144A, ARG78I, ARG85A, ASN45I, ASN46I, ASP143A, ASP76I, CYS116A, GLN87A, GLU114A, GLU117A, GLU74I, GLU90A, GLY107I, GLY113A, GLY120A, HIS119A, HIS53I, HIS88A, ILE121A, LEU104I, LEU72I, LEU91A, LYS103A, LYS106I, LYS118A, LYS122A, LYS79I, PHE115A, PHE123A, PRO109A, PRO109I, PRO136A, PRO141A, PRO42I, PRO89A, SER108A, SER108I, SER111A, SER44I, SER75I, THR110A, TYR105I, TYR43I, VAL41I
• A-J: ARG144A, ARG144J, ARG85A, ARG85J, ARG94A, ASN49A, ASN49J, ASN63A, ASP143A, ASP143J, ASP92A, GLN47J, GLN48A, GLN48J, GLN87A, GLN87J, GLU135A, GLU139A, GLU139J, GLU86A, GLU86J, GLU90A, GLU90J, GLY120A, HIS53A, HIS53J, HIS88A, HIS88J, ILE65A, ILE84A, ILE84J, LEU145A, LEU145J, LEU83A, LEU83J, LEU91A, LEU91J, LYS122A, LYS137A, LYS138A, LYS138J, LYS146A, LYS146J, PHE142A, PHE142J, PRO136A, PRO141A, PRO141J, PRO89A, PRO89J, SER51A, SER51J, SER52A, SER52J, THR54A, THR54J, TYR50A, TYR50J, VAL140A, VAL140J
• B-C: ARG144B, ARG144C, ARG85B, ARG85C, ASN49B, ASN49C, ASP143B, ASP143C, ASP92B, GLN47C, GLN48B, GLN48C, GLN87B, GLN87C, GLU139B, GLU139C, GLU86B, GLU86C, GLU90B, GLU90C, HIS53B, HIS53C, HIS88B, HIS88C, ILE84B, ILE84C, LEU145B, LEU145C, LEU83B, LEU83C, LEU91B, LEU91C, LYS122B, LYS138B, LYS138C, LYS146B, LYS146C, PHE142B, PHE142C, PRO136B, PRO141B, PRO141C, PRO89B, PRO89C, SER51B, SER51C, SER52B, SER52C, THR54B, THR54C, TYR50B, TYR50C, VAL140B, VAL140C
• B-D: ALA124B, ARG101B, ARG144B, ARG78D, ASN45D, ASN46D, ASP125B, ASP143B, ASP76D, CYS116B, GLN87B, GLU114B, GLU117B, GLU131B, GLU74D, GLU90B, GLY107D, GLY113B, GLY120B, HIS88B, LEU104D, LEU91B, LYS103B, LYS103D, LYS106D, LYS118B, LYS122B, LYS79D, PHE115B, PHE123B, PRO109B, PRO109D, PRO141B, PRO42D, PRO89B, SER100B, SER108D, SER111B, SER44D, SER75D, SER99B, THR110B, THR110D, TYR105D, TYR112B, TYR43D, VAL41D
• B-I: GLN26I, LYS106B, LYS22I, LYS30I
• B-J: ALA124J, ALA130J, ARG101J, ARG144J, ARG78B, ARG94J, ASN45B, ASN46B, ASP125J, ASP143J, ASP76B, ASP92J, GLN87J, GLU114B, GLU114J, GLU117J, GLU131J, GLU135J, GLU74B, GLU90J, GLY107B, GLY113J, GLY120J, HIS119B, HIS88J, ILE128J, ILE133J, LEU104B, LEU127J, LEU72B, LEU91J, LYS103B, LYS103J, LYS106B, LYS118B, LYS118J, LYS122J, LYS126J, LYS134J, LYS79B, PHE115B, PHE123J, PHE97J, PRO109B, PRO129J, PRO136J, PRO141J, PRO42B, PRO89J, SER100J, SER108B, SER111J, SER44B, SER75B, SER99J, THR102J, THR110B, TRP132J, TRP73B, TYR105B, TYR112B, TYR43B, VAL41B, VAL96J
• C-D: ALA124C, ALA124D, ALA130C, ALA130D, ARG144C, ARG144D, ARG147C, ARG147D, ARG85C, ARG85D, ASN45C, ASN45D, ASN46C, ASN46D, ASN49C, ASN49D, ASN63C, ASN63D, ASP125C, ASP125D, ASP143C, ASP143D, ASP21C, ASP21D, ASP58C, ASP58D, ASP76C, ASP76D, ASP77D, ASP92D, GLN26C, GLN26D, GLN47C, GLN47D, GLN48C, GLN48D, GLN87C, GLN87D, GLU131C, GLU131D, GLU20C, GLU20D, GLU28C, GLU28D, GLU35C, GLU35D, GLU37C, GLU37D, GLU38C, GLU38D, GLU68C, GLU68D, GLU86C, GLU86D, GLU90C, GLU90D, GLY18C, GLY18D, GLY31C, GLY31D, GLY64D, GLY71C, GLY71D, HIS53C, HIS53D, HIS81D, HIS88C, HIS88D, ILE128C, ILE128D, ILE133C, ILE133D, ILE32C, ILE32D, ILE65C, ILE65D, ILE84C, ILE84D, ILE93C, ILE93D, ILE95C, ILE95D, LEU127C, LEU127D, LEU145C, LEU145D, LEU19C, LEU19D, LEU27C, LEU27D, LEU60C, LEU60D, LEU61C, LEU61D, LEU72C, LEU72D, LEU83C, LEU83D, LEU91C, LEU91D, LYS126C, LYS126D, LYS134C, LYS134D, LYS146C, LYS146D, LYS148C, LYS148D, LYS22C, LYS22D, LYS25C, LYS25D, LYS30C, LYS30D, LYS33C, LYS33D, LYS40C, LYS40D, LYS70C, LYS70D, LYS79C, LYS79D, LYS80C, LYS80D, MET17C, MET17D, PHE142C, PHE142D, PHE34C, PHE34D, PHE59C, PHE59D, PHE66C, PHE66D, PHE97C, PHE97D, PRO129C, PRO129D, PRO141C, PRO141D, PRO42C, PRO42D, PRO57C, PRO57D, PRO62C, PRO62D, SER24C, SER24D, SER44C, SER44D, SER51C, SER51D, SER52C, SER52D, SER98C, SER98D, SER99C, SER99D, THR54C, THR54D, THR56C, THR56D, THR69C, THR69D, TRP132C, TRP132D, TRP39C, TRP39D, TYR36C, TYR36D, TYR43C, TYR43D, TYR50C, TYR50D, TYR55C, TYR55D, VAL140C, VAL140D, VAL23C, VAL23D, VAL41C, VAL41D, VAL67C, VAL67D, VAL96C, VAL96D
• C-E: ALA124E, ARG101E, ARG144E, ARG78C, ARG85E, ARG94E, ASN45C, ASN46C, ASP125E, ASP143E, ASP76C, CYS116E, GLN87E, GLU114E, GLU117E, GLU131E, GLU74C, GLU86E, GLU90E, GLY107C, GLY113E, GLY120E, HIS53C, HIS88E, LEU104C, LEU91E, LYS103C, LYS103E, LYS106C, LYS118E, LYS122E, LYS79C, PHE115E, PHE123E, PRO109C, PRO109E, PRO129E, PRO136E, PRO141E, PRO42C, PRO89E, SER100E, SER108C, SER111E, SER44C, SER51C, SER75C, SER99E, THR102E, THR110C, THR110E, TRP132E, TYR105C, TYR112E, TYR43C, VAL41C
• C-I: ARG101C, ARG101I, GLU114C, GLU114I, GLU117C, GLY107I, GLY113C, LEU104C, LYS103C, LYS103I, LYS106I, LYS118C, PRO109C, PRO109I, SER108C, SER108I, SER111C, THR110C, THR110I, TYR105I
• D-E: ARG144D, ARG144E, ARG85D, ARG85E, ASN49D, ASN49E, ASP143D, ASP143E, ASP92D, ASP92E, GLN47D, GLN47E, GLN48D, GLN48E, GLN87D, GLN87E, GLU139D, GLU139E, GLU86D, GLU86E, GLU90D, GLU90E, HIS53D, HIS53E, HIS88D, HIS88E, ILE84D, ILE84E, LEU145D, LEU145E, LEU83D, LEU83E, LEU91D, LEU91E, LYS137D, LYS137E, LYS138D, LYS138E, LYS146D, LYS146E, PRO136D, PRO136E, PRO141D, PRO141E, PRO89D, PRO89E, SER51D, SER51E, SER52D, SER52E, THR54D, THR54E, TYR50D, TYR50E, VAL140D, VAL140E
• D-F: ALA124D, ARG101D, ARG144D, ARG78F, ARG85D, ARG94D, ASN45F, ASN46F, ASP125D, ASP143D, ASP76F, CYS116D, GLN87D, GLU114D, GLU117D, GLU131D, GLU74F, GLU86D, GLU90D, GLY107F, GLY113D, GLY120D, HIS53F, HIS88D, LEU104F, LEU91D, LYS103D, LYS103F, LYS106F, LYS118D, LYS122D, LYS79F, PHE115D, PHE123D, PRO109D, PRO109F, PRO129D, PRO136D, PRO141D, PRO42F, PRO89D, SER100D, SER108F, SER111D, SER44F, SER51F, SER75F, SER99D, THR102D, THR110D, THR110F, TRP132D, TYR105F, TYR112D, TYR43F, VAL41F
• D-J: ARG101J, GLU114J, PRO109D
• E-F: ALA124E, ALA124F, ALA130E, ALA130F, ARG144E, ARG144F, ARG147E, ARG147F, ARG85E, ARG85F, ASN45E, ASN45F, ASN46E, ASN46F, ASN49E, ASN49F, ASN63E, ASN63F, ASP125E, ASP125F, ASP143E, ASP143F, ASP21E, ASP21F, ASP58E, ASP58F, ASP76E, ASP76F, ASP77E, ASP92E, GLN26E, GLN26F, GLN47E, GLN47F, GLN48E, GLN48F, GLN87E, GLN87F, GLU131E, GLU131F, GLU20E, GLU20F, GLU28E, GLU28F, GLU35E, GLU35F, GLU37E, GLU37F, GLU38E, GLU38F, GLU68E, GLU68F, GLU86E, GLU86F, GLU90E, GLU90F, GLY18E, GLY18F, GLY31E, GLY31F, GLY64E, GLY71E, GLY71F, HIS53E, HIS53F, HIS81E, HIS88E, HIS88F, ILE128E, ILE128F, ILE133E, ILE133F, ILE32E, ILE32F, ILE65E, ILE65F, ILE84E, ILE84F, ILE93E, ILE93F, ILE95E, ILE95F, LEU127E, LEU127F, LEU145E, LEU145F, LEU19E, LEU19F, LEU27E, LEU27F, LEU60E, LEU60F, LEU61E, LEU61F, LEU72E, LEU72F, LEU83E, LEU83F, LEU91E, LEU91F, LYS126E, LYS126F, LYS134E, LYS134F, LYS146E, LYS146F, LYS148E, LYS148F, LYS22E, LYS22F, LYS25E, LYS25F, LYS30E, LYS30F, LYS33E, LYS33F, LYS40E, LYS40F, LYS70E, LYS70F, LYS79E, LYS79F, LYS80E, LYS80F, MET17E, MET17F, PHE142E, PHE142F, PHE34E, PHE34F, PHE59E, PHE59F, PHE66E, PHE66F, PHE97E, PHE97F, PRO129E, PRO129F, PRO141E, PRO141F, PRO42E, PRO42F, PRO57E, PRO57F, PRO62E, PRO62F, SER24E, SER24F, SER29F, SER44E, SER44F, SER51E, SER51F, SER52E, SER52F, SER98E, SER98F, SER99E, SER99F, THR54E, THR54F, THR56E, THR56F, THR69E, THR69F, TRP132E, TRP132F, TRP39E, TRP39F, TYR36E, TYR36F, TYR43E, TYR43F, TYR50E, TYR50F, TYR55E, TYR55F, VAL140E, VAL140F, VAL23E, VAL23F, VAL41E, VAL41F, VAL67E, VAL67F, VAL96E, VAL96F
• E-G: ALA124G, ARG101G, ARG144G, ARG78E, ASN45E, ASN46E, ASP125G, ASP143G, ASP76E, CYS116G, GLN87G, GLU114G, GLU117G, GLU131G, GLU74E, GLU90G, GLY107E, GLY113G, GLY120G, HIS119G, HIS88G, LEU104E, LEU91G, LYS103E, LYS103G, LYS106E, LYS118G, LYS122G, LYS79E, PHE115G, PHE123G, PRO109E, PRO109G, PRO141G, PRO42E, PRO89G, SER100G, SER108E, SER111G, SER44E, SER75E, THR110E, THR110G, TYR105E, TYR112G, TYR43E, VAL41E
• E-H: GLN26E, LYS106H, LYS22E, LYS30E
• E-I: ARG101I, GLU114I, PRO109E
• F-G: ARG144F, ARG144G, ARG85F, ARG85G, ASN49F, ASN49G, ASP143F, ASP143G, ASP92G, GLN47F, GLN48F, GLN48G, GLN87F, GLN87G, GLU139F, GLU139G, GLU86F, GLU86G, GLU90F, GLU90G, HIS53F, HIS53G, HIS88F, HIS88G, ILE84F, ILE84G, LEU145F, LEU145G, LEU83F, LEU83G, LEU91F, LEU91G, LYS122G, LYS138F, LYS138G, LYS146F, LYS146G, PHE142F, PHE142G, PRO136G, PRO141F, PRO141G, PRO89F, PRO89G, SER51F, SER51G, SER52F, SER52G, THR54F, THR54G, TYR50F, TYR50G, VAL140F, VAL140G
• F-H: ALA124F, ALA130F, ARG101F, ARG144F, ARG78H, ARG94F, ASN45H, ASN46H, ASP125F, ASP143F, ASP76H, ASP77H, GLN87F, GLU114F, GLU117F, GLU131F, GLU135F, GLU74H, GLU90F, GLY107H, GLY113F, GLY120F, HIS119H, HIS88F, ILE128F, LEU104H, LEU127F, LEU72H, LEU91F, LYS103H, LYS106H, LYS118F, LYS118H, LYS122F, LYS126F, LYS134F, LYS79H, PHE115H, PHE123F, PRO109H, PRO129F, PRO136F, PRO141F, PRO42H, PRO89F, SER100F, SER108H, SER111F, SER44H, SER75H, SER99F, THR110H, TRP132F, TRP73H, TYR105H, TYR112H, TYR43H, VAL41H, VAL96F
• F-J: ARG101F, ARG101J, GLU114F, GLU114J, GLU117F, GLY107J, GLY113F, LEU104F, LYS103F, LYS103J, LYS106J, LYS118F, PRO109F, PRO109J, SER108F, SER108J, SER111F, THR110F, THR110J, TYR105J
• G-H: ALA124G, ALA124H, ALA130G, ALA130H, ARG144G, ARG144H, ARG147G, ARG147H, ARG85G, ARG85H, ASN45G, ASN45H, ASN46G, ASN46H, ASN49G, ASN49H, ASN63G, ASN63H, ASP125G, ASP125H, ASP143G, ASP143H, ASP21G, ASP21H, ASP58G, ASP58H, ASP76G, ASP76H, ASP77H, ASP92H, GLN26G, GLN26H, GLN47G, GLN47H, GLN48G, GLN48H, GLN87G, GLN87H, GLU131G, GLU131H, GLU20G, GLU20H, GLU28G, GLU28H, GLU35G, GLU35H, GLU37G, GLU37H, GLU38G, GLU38H, GLU68G, GLU68H, GLU86G, GLU86H, GLU90G, GLU90H, GLY18G, GLY18H, GLY31G, GLY31H, GLY64G, GLY64H, GLY71G, GLY71H, HIS53G, HIS53H, HIS81G, HIS81H, HIS88G, HIS88H, ILE128G, ILE128H, ILE133G, ILE133H, ILE32G, ILE32H, ILE65G, ILE65H, ILE84G, ILE84H, ILE93G, ILE93H, ILE95G, ILE95H, LEU127G, LEU127H, LEU145G, LEU145H, LEU19G, LEU19H, LEU27G, LEU27H, LEU60G, LEU60H, LEU61G, LEU61H, LEU72G, LEU72H, LEU83G, LEU83H, LEU91G, LEU91H, LYS126G, LYS126H, LYS134G, LYS134H, LYS146G, LYS146H, LYS148G, LYS148H, LYS22G, LYS22H, LYS25G, LYS25H, LYS30G, LYS30H, LYS33G, LYS33H, LYS40G, LYS40H, LYS70G, LYS70H, LYS79G, LYS79H, LYS80G, LYS80H, MET17G, MET17H, PHE142G, PHE142H, PHE34G, PHE34H, PHE59G, PHE59H, PHE66G, PHE66H, PHE97G, PHE97H, PRO129G, PRO129H, PRO141G, PRO141H, PRO42G, PRO42H, PRO57G, PRO57H, PRO62G, PRO62H, SER24G, SER24H, SER29H, SER44G, SER44H, SER51G, SER51H, SER52G, SER52H, SER98G, SER98H, SER99G, SER99H, THR54G, THR54H, THR56G, THR56H, THR69G, THR69H, TRP132G, TRP132H, TRP39G, TRP39H, TYR36G, TYR36H, TYR43G, TYR43H, TYR50G, TYR50H, TYR55G, TYR55H, VAL140G, VAL140H, VAL23G, VAL23H, VAL41G, VAL41H, VAL67G, VAL67H, VAL96G, VAL96H
• G-I: ALA124I, ALA130I, ARG101I, ARG144I, ARG78G, ARG94I, ASN45G, ASN46G, ASP125I, ASP143I, ASP76G, ASP92I, GLN87I, GLU114G, GLU114I, GLU117I, GLU131I, GLU135I, GLU74G, GLU90I, GLY107G, GLY113I, GLY120I, HIS119G, HIS88I, ILE128I, ILE133I, LEU104G, LEU127I, LEU72G, LEU91I, LYS103G, LYS103I, LYS106G, LYS118G, LYS118I, LYS122I, LYS126I, LYS134I, LYS79G, PHE115G, PHE123I, PHE97I, PRO109G, PRO129I, PRO136I, PRO141I, PRO42G, PRO89I, SER100I, SER108G, SER111I, SER44G, SER75G, SER99I, THR102I, THR110G, TRP132I, TRP73G, TYR105G, TYR112G, TYR43G, VAL41G, VAL96I
• G-J: GLN26J, LYS106G, LYS22J, LYS30J
• H-I: ARG144H, ARG144I, ARG85H, ARG85I, ARG94H, ASN49H, ASN49I, ASN63H, ASP143H, ASP143I, ASP92H, GLN47I, GLN48H, GLN48I, GLN87H, GLN87I, GLU135H, GLU139H, GLU139I, GLU86H, GLU86I, GLU90H, GLU90I, GLY120H, HIS53H, HIS53I, HIS88H, HIS88I, ILE65H, ILE84H, ILE84I, LEU145H, LEU145I, LEU83H, LEU83I, LEU91H, LEU91I, LYS122H, LYS137H, LYS138H, LYS138I, LYS146H, LYS146I, PHE142H, PHE142I, PRO136H, PRO141H, PRO141I, PRO89H, PRO89I, SER51H, SER51I, SER52H, SER52I, THR54H, THR54I, TYR50H, TYR50I, VAL140H, VAL140I
• H-J: ARG101H, ARG144H, ARG78J, ARG85H, ASN45J, ASN46J, ASP143H, ASP76J, CYS116H, GLN87H, GLU114H, GLU117H, GLU74J, GLU90H, GLY107J, GLY113H, GLY120H, HIS119H, HIS53J, HIS88H, ILE121H, LEU104J, LEU72J, LEU91H, LYS103H, LYS106J, LYS118H, LYS122H, LYS79J, PHE115H, PHE123H, PRO109H, PRO109J, PRO136H, PRO141H, PRO42J, PRO89H, SER108H, SER108J, SER111H, SER44J, SER75J, THR110H, TYR105J, TYR43J, VAL41J
• I-J: ALA124I, ALA124J, ALA130I, ALA130J, ARG144I, ARG144J, ARG147I, ARG147J, ARG85I, ARG85J, ASN45I, ASN45J, ASN46I, ASN46J, ASN49I, ASN49J, ASN63I, ASN63J, ASP125I, ASP125J, ASP143I, ASP143J, ASP21I, ASP21J, ASP58I, ASP58J, ASP76I, ASP76J, ASP77J, GLN26I, GLN26J, GLN47I, GLN47J, GLN48I, GLN48J, GLN87I, GLN87J, GLU131I, GLU131J, GLU20I, GLU20J, GLU28I, GLU28J, GLU35I, GLU35J, GLU37I, GLU37J, GLU38I, GLU38J, GLU68I, GLU68J, GLU90I, GLU90J, GLY18I, GLY18J, GLY31I, GLY31J, GLY71I, GLY71J, HIS53I, HIS53J, HIS81I, HIS81J, HIS88I, HIS88J, ILE128I, ILE128J, ILE133I, ILE133J, ILE32I, ILE32J, ILE65I, ILE65J, ILE84I, ILE84J, ILE93I, ILE93J, ILE95I, ILE95J, LEU127I, LEU127J, LEU145I, LEU145J, LEU19I, LEU19J, LEU27I, LEU27J, LEU60I, LEU60J, LEU61I, LEU61J, LEU72I, LEU72J, LEU83I, LEU83J, LEU91I, LEU91J, LYS126I, LYS126J, LYS134I, LYS134J, LYS146I, LYS146J, LYS148I, LYS148J, LYS22I, LYS22J, LYS25I, LYS25J, LYS30I, LYS30J, LYS33I, LYS33J, LYS40I, LYS40J, LYS70I, LYS70J, LYS79I, LYS79J, LYS80I, LYS80J, MET17I, MET17J, PHE142I, PHE142J, PHE34I, PHE34J, PHE59I, PHE59J, PHE66I, PHE66J, PHE97I, PHE97J, PRO129I, PRO129J, PRO141I, PRO141J, PRO42I, PRO42J, PRO57I, PRO57J, PRO62I, PRO62J, SER24I, SER24J, SER29I, SER29J, SER44I, SER44J, SER51I, SER51J, SER52I, SER52J, SER98I, SER98J, SER99I, SER99J, THR54I, THR54J, THR56I, THR56J, THR69I, THR69J, TRP132I, TRP132J, TRP39I, TRP39J, TYR36I, TYR36J, TYR43I, TYR43J, TYR50I, TYR50J, TYR55I, TYR55J, VAL140I, VAL140J, VAL23I, VAL23J, VAL41I, VAL41J, VAL67I, VAL67J, VAL96I, VAL96J