3C9A

high resolution crystal structure of argos bound to the egf domain of spitz

• Total interactions analyzed: 6
• Total true interactions: 4
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 38
  • Norm. En. per Res.: -5.1359
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-34.7968	-27.8167	-136.457	-199.0706	54	3	0	4753	3	18	16
A-C	-15.4726	-29.0508	-349.706	-394.2294	125	10	9	14138	4	19	18
B-C	-55.9891	-22.4037	-116.77	-195.1629	38	14	1	4100	3	18	19
B-D	-4.4373	-11.7611	-332.02	-348.2184	123	14	8	14450	2	19	20

Interface residues

• A-B: ALA399B, ARG101B, ARG329A, ARG340A, ARG367B, ARG387B, ARG98B, ASN334A, ASP335A, ASP372B, ASP97B, ASP99B, GLN368B, GLN394B, GLN409B, GLU129B, GLU330A, GLU369B, GLU373B, GLY333A, GLY338A, GLY396B, HIS391B, HIS392B, ILE332A, ILE398B, LEU326A, LEU342A, LEU371B, LEU404A, LYS328A, LYS366B, MET416B, PHE343A, PHE370B, PHE403A, PRO331A, PRO337A, PRO389B, SER336A, SER395B, THR130B, THR327A, THR393B, TYR128B, TYR297A, TYR325A, TYR339A, TYR341A, TYR411B, TYR414B, VAL364B, VAL374B, VAL397B
• A-C: ALA304A, ALA305A, ALA344A, ALA60C, ALA71C, ALA75C, ARG277A, ARG295A, ARG329A, ARG340A, ARG350A, ARG355A, ARG365A, ARG367A, ARG92C, ASN308A, ASN321A, ASN375A, ASN377A, ASN407A, ASN65C, ASP274A, ASP372A, ASP59C, ASP76C, CYS345A, CYS353A, CYS359A, CYS380A, CYS54C, CYS63C, CYS69C, CYS82C, CYS84C, CYS93C, GLN105A, GLN312A, GLN354A, GLN357A, GLN381A, GLN409A, GLN91C, GLU134A, GLU311A, GLU373A, GLU401A, GLU405A, GLU56C, GLU83C, GLU94C, GLU97C, GLY400A, GLY413A, GLY90C, HIS293A, ILE376A, ILE398A, ILE408A, ILE74C, LEU301A, LEU326A, LEU342A, LEU348A, LEU351A, LEU361A, LEU379A, LEU404A, LEU64C, LEU77C, LYS124A, LYS275A, LYS328A, LYS356A, LYS360A, LYS366A, LYS53C, LYS73C, LYS96C, MET89C, PHE294A, PHE343A, PHE362A, PHE403A, PHE58C, PHE70C, PHE88C, PRO347A, PRO358A, PRO50C, PRO55C, PRO78C, SER346A, SER378A, SER402A, SER412A, SER81C, THR300A, THR302A, THR303A, THR310A, THR324A, THR327A, THR349A, THR363A, THR410A, THR51C, THR57C, TRP132A, TRP299A, TRP61C, TYR325A, TYR339A, TYR341A, TYR411A, TYR414A, TYR52C, TYR62C, TYR80C, TYR95C, VAL309A, VAL323A, VAL364A, VAL374A, VAL72C, VAL79C
• B-C: ALA71C, ALA85C, ARG101B, ARG367B, ARG98B, ASP108B, ASP59C, ASP66C, ASP97B, ASP99B, CYS54C, CYS69C, CYS82C, CYS84C, GLN368B, GLU129B, GLU369B, GLU83C, HIS68C, ILE102B, ILE74C, ILE86C, LEU103B, LEU371B, LYS366B, LYS53C, PHE370B, PHE70C, PRO131B, PRO50C, PRO55C, SER81C, THR130B, THR51C, TYR52C, VAL100B, VAL72C, VAL79C
• B-D: ALA344B, ALA399B, ALA60D, ALA71D, ALA75D, ARG277B, ARG295B, ARG329B, ARG340B, ARG350B, ARG355B, ARG365B, ARG367B, ARG92D, ASN308B, ASN375B, ASN377B, ASN407B, ASN65D, ASP126B, ASP372B, ASP59D, ASP76D, CYS345B, CYS353B, CYS359B, CYS380B, CYS54D, CYS63D, CYS82D, CYS84D, CYS93D, GLN105B, GLN136B, GLN312B, GLN354B, GLN357B, GLN381B, GLN409B, GLN91D, GLU134B, GLU311B, GLU373B, GLU401B, GLU405B, GLU56D, GLU83D, GLU94D, GLU97D, GLY338B, GLY400B, GLY413B, GLY90D, HIS293B, ILE376B, ILE398B, ILE408B, ILE74D, LEU301B, LEU326B, LEU342B, LEU348B, LEU351B, LEU361B, LEU379B, LEU404B, LEU64D, LEU77D, LYS124B, LYS275B, LYS328B, LYS356B, LYS360B, LYS366B, LYS53D, LYS73D, LYS96D, MET89D, PHE294B, PHE343B, PHE362B, PHE403B, PHE58D, PHE70D, PRO347B, PRO358B, PRO50D, PRO55D, PRO78D, SER346B, SER378B, SER402B, SER412B, SER81D, THR300B, THR302B, THR303B, THR310B, THR324B, THR327B, THR349B, THR363B, THR410B, THR51D, THR57D, TRP132B, TRP299B, TRP61D, TYR325B, TYR339B, TYR341B, TYR411B, TYR414B, TYR52D, TYR62D, TYR80D, TYR95D, VAL309B, VAL323B, VAL364B, VAL374B, VAL72D, VAL79D