3C7K

molecular architecture of galphao and the structural basis for rgs16-mediated deactivation

• Total interactions analyzed: 6
• Total true interactions: 2
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 106
  • Norm. En. per Res.: -3.8034
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-79.6389	-86.0728	-237.451	-403.1627	106	20	1	9248	7	79	66
C-D	-47.4966	-59.0501	-235.092	-341.6387	98	22	1	9097	4	83	64

Interface residues

• A-B: ALA125B, ARG122B, ARG136B, ARG159B, ARG169B, ARG179A, ARG206A, ARG209A, ARG243A, ARG86A, ASN130B, ASN76A, ASN90B, ASP116A, ASP132B, ASP165B, ASP201A, ASP238A, ASP65A, CYS215A, GLN148A, GLN205A, GLN68A, GLN79A, GLU119B, GLU124B, GLU128B, GLU134B, GLU137B, GLU163B, GLU187A, GLU208A, GLU237A, GLU239A, GLU64A, GLU85B, GLU88B, GLU89B, GLY156B, GLY184A, GLY203A, GLY204A, GLY42A, GLY63A, HIS133B, HIS214A, HIS236A, ILE121B, ILE131B, ILE185A, ILE213A, ILE78A, LEU161B, LEU171B, LEU235A, LEU82B, LYS127B, LYS157B, LYS164B, LYS172B, LYS181A, LYS210A, LYS211A, LYS67A, LYS83B, MET114A, MET162B, PHE200A, PHE216A, PHE65B, PHE78B, PHE81B, PHE86B, PRO126B, PRO168B, PRO71A, SER123B, SER166B, SER207A, SER47A, SER62A, SER75A, SER87B, THR117A, THR135B, THR158B, THR160B, THR182A, THR183A, THR188A, THR240A, THR241A, THR84B, THR90A, TRP212A, TYR120B, TYR167B, TYR69A, VAL111A, VAL129B, VAL180A, VAL186A, VAL202A, VAL234A, VAL66A, VAL72A
• C-D: ALA125D, ARG122D, ARG136D, ARG159D, ARG169D, ARG179C, ARG206C, ARG209C, ARG86C, ASN130D, ASN76C, ASN90D, ASP116C, ASP132D, ASP165D, ASP201C, ASP238C, ASP65C, CYS215C, GLN148C, GLN205C, GLN68C, GLN79C, GLU124D, GLU128D, GLU134D, GLU137D, GLU163D, GLU187C, GLU208C, GLU237C, GLU239C, GLU43C, GLU64C, GLU85D, GLU88D, GLU89D, GLY184C, GLY203C, GLY204C, GLY42C, HIS133D, HIS214C, HIS236C, ILE121D, ILE131D, ILE185C, ILE213C, LEU161D, LEU171D, LEU235C, LEU82D, LYS127D, LYS140D, LYS157D, LYS164D, LYS172D, LYS181C, LYS210C, LYS211C, LYS54C, MET114C, MET162D, PHE216C, PHE81D, PHE86D, PRO126D, PRO168D, PRO71C, SER123D, SER166D, SER207C, SER47C, SER62C, SER75C, SER87D, THR117C, THR135D, THR158D, THR160D, THR182C, THR183C, THR188C, THR240C, THR241C, THR84D, THR90C, TRP212C, TYR120D, TYR167D, TYR69C, VAL129D, VAL180C, VAL186C, VAL202C, VAL234C, VAL50C, VAL72C