3BT2

structure of urokinase receptor, urokinase and vitronectin complex

• Total interactions analyzed: 10
• Total true interactions: 5
• Strongest Interaction:
  • Chains: H-U
  • Int. Res.: 53
  • Norm. En. per Res.: -3.5397
• Hub Node: L(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-U	-16.7613	-30.4936	-295.598	-342.8529	123	9	5	12343	1	42	27
B-U	-6.9444	-32.1708	-153.888	-193.0033	63	11	1	5809	3	12	10
L-H	-23.0366	-34.6444	-466.741	-524.422	181	10	8	18027	5	12	14
L-U	-11.2797	0.0	-77.4346	-88.7143	29	2	0	2320	0	0	3
H-U	-29.6537	-27.4524	-130.497	-187.603	53	4	0	4424	1	9	7

Interface residues

• A-U: ALA255U, ALA86A, ALA91A, ARG142U, ARG25U, ARG30U, ARG53U, ARG88A, ASN10A, ASN157U, ASN22A, ASN27A, ASN32A, ASN52U, ASN75A, ASN9U, ASP102U, ASP11U, ASP12A, ASP140U, ASP141U, ASP254U, CYS11A, CYS12U, CYS13A, CYS147U, CYS19A, CYS31A, CYS33A, CYS42A, CYS45U, CYS6U, GLN40A, GLU33U, GLU34U, GLU36U, GLU37U, GLU39U, GLU42U, GLU43A, GLU68U, GLY10U, GLY148U, GLY152U, GLY253U, GLY38A, GLY39A, GLY97A, HIS128U, HIS166U, HIS29A, HIS41A, HIS47U, HIS85A, HIS87A, ILE28A, ILE28U, ILE44A, LEU123U, LEU144U, LEU150U, LEU168U, LEU252U, LEU31U, LEU38U, LEU40U, LEU55U, LEU61U, LEU66U, LEU80A, LEU92A, LEU96A, LYS139U, LYS23A, LYS35A, LYS43U, LYS46A, LYS50U, LYS62U, LYS7U, LYS98A, MET246U, MET258U, PHE165U, PHE167U, PHE256U, PHE25A, PHE37A, PRO151U, SER100U, SER101U, SER21A, SER257U, SER26A, SER44U, SER56U, SER65U, SER89A, SER9A, THR127U, THR164U, THR18A, THR26U, THR27U, THR46U, THR51U, THR54U, THR59U, THR64U, THR67U, THR8U, TRP129U, TRP30A, TYR149U, TYR24A, TYR57U, VAL125U, VAL126U, VAL20A, VAL29U, VAL41U, VAL69U, VAL70U
• B-U: ARG116U, ARG30U, ARG58U, ARG89U, ARG91U, ASN14B, ASP16B, ASP22B, CYS115U, CYS147U, CYS19B, CYS21B, CYS25B, CYS31B, CYS95U, GLN111U, GLN114U, GLN20B, GLN29B, GLU120U, GLU23B, GLU33U, GLU34U, GLU36U, GLU37U, GLU39U, GLU94U, GLY12B, GLY35U, GLY60U, ILE63U, LEU113U, LEU24B, LEU31U, LEU55U, LEU61U, LEU66U, LEU93U, LYS17B, LYS18B, LYS40B, LYS62U, PHE13B, PRO41B, SER112U, SER117U, SER26B, SER30B, SER56U, SER65U, SER88U, SER90U, THR36B, THR54U, THR64U, TRP32U, TYR27B, TYR28B, TYR35B, TYR57U, TYR87U, TYR92U, VAL15B
• L-H: ALA125H, ALA129L, ALA163H, ALA206H, ALA207H, ALA208H, ALA55L, ALA93H, ARG94H, ASN136L, ASN137L, ASN160L, ASN60H, ASN92L, ASP101H, ASP164L, ASP166L, ASP169L, ASP1L, CYS133L, CYS135H, CYS88L, CYS92H, GLN105H, GLN123L, GLN166H, GLN37L, GLN38L, GLN39H, GLN43H, GLN6H, GLN89L, GLN90L, GLU122L, GLU46H, GLU50L, GLU58H, GLU61H, GLY100L, GLY101L, GLY104H, GLY106H, GLY127L, GLY128L, GLY134H, GLY157H, GLY157L, GLY41L, GLY42H, GLY44H, GLY49H, GLY96H, GLY99L, HIS159H, HIS34L, HIS35H, HIS98H, ILE116L, ILE205H, ILE48H, ILE48L, ILE51L, ILE85L, LEU124H, LEU124L, LEU133H, LEU135L, LEU136H, LEU159L, LEU165H, LEU169H, LEU172H, LEU178L, LEU180L, LEU45H, LEU54L, LYS103L, LYS138H, LYS141L, LYS168L, LYS203H, LYS204H, LYS206L, LYS38H, LYS39L, LYS45L, LYS53L, LYS62H, LYS64H, MET130H, MET174L, MET33L, PHE100H, PHE117L, PHE134L, PHE138L, PHE161H, PHE208L, PHE49L, PHE91H, PHE96L, PHE98L, PRO118L, PRO119L, PRO123H, PRO126H, PRO162H, PRO41H, PRO44L, PRO46L, PRO94L, PRO97H, SER115L, SER120H, SER120L, SER121L, SER126L, SER129H, SER130L, SER155H, SER156H, SER161L, SER167H, SER167L, SER173H, SER173L, SER174H, SER175H, SER175L, SER176L, SER40L, SER43L, SER56L, THR113L, THR125L, THR132H, THR160H, THR163L, THR171H, THR171L, THR177H, THR177L, THR179L, THR42L, THR97L, TRP103H, TRP149H, TRP162L, TRP183H, TRP35L, TRP36H, TRP47H, TRP47L, TRP50H, TRP91L, TRP95H, TRP99H, TYR100H, TYR122H, TYR170H, TYR172L, TYR32L, TYR33H, TYR36L, TYR59H, TYR86L, TYR87L, TYR93L, VAL102H, VAL114L, VAL121H, VAL131H, VAL131L, VAL132L, VAL137H, VAL158H, VAL158L, VAL164H, VAL176H, VAL37H, VAL89H
• L-U: ARG192U, ARG216U, ASN186U, ASN190U, ASN92L, ASP214U, CYS215U, GLN189U, GLN193U, GLN90L, GLU183U, GLU185U, GLU50L, GLY191U, GLY217U, HIS34L, ILE2L, LEU184U, LEU187U, LYS53L, PHE96L, PRO180U, PRO188U, PRO94L, SER31L, TRP91L, TYR32L, TYR93L, VAL30L
• H-U: ALA242U, ALA244U, ARG192U, ARG216U, ASN186U, ASN190U, ASN220U, ASN31H, ASN56H, ASP55H, CYS215U, CYS222U, CYS266U, GLN189U, GLN193U, GLN221U, GLU58H, GLY179U, GLY191U, GLY217U, GLY53H, GLY96H, HIS35H, HIS52H, HIS98H, ILE51H, LEU182U, LEU187U, LYS268U, LYS64H, MET219U, PHE167U, PHE32H, PHE52H, PRO180U, PRO188U, PRO218U, PRO97H, SER156U, SER245U, SER269U, SER54H, THR243U, THR267U, THR30H, THR57H, TRP47H, TRP50H, TRP95H, TRP99H, TYR100H, TYR33H, TYR59H