3BL8

crystal structure of the extracellular domain of neuroligin 2a from mouse

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 78
  • Norm. En. per Res.: -2.855
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	0.0	-0.0005	-0.0005	2	0	0	1	0	0	0
A-C	0.0	-35.602	-191.864	-227.466	87	1	8	8329	5	44	44
B-C	-35.4739	-42.678	-144.539	-222.691	78	8	0	5703	4	36	25
B-D	-5.8759	2.6608	-183.687	-186.9021	89	5	9	8259	2	42	44
C-D	-17.2452	-33.7408	-33.5714	-84.5574	34	4	0	1361	2	17	9

Interface residues

• A-B: ASN522B, GLU422A
• A-C: ALA439A, ALA439C, ALA595A, ALA595C, ALA599A, ALA599C, ARG428A, ARG428C, ARG441A, ARG441C, ARG447A, ARG594A, ARG594C, ASN592A, ASN592C, ASN596A, ASN596C, ASN610C, ASP425A, ASP425C, ASP437A, ASP437C, ASP440A, ASP440C, ASP442A, ASP442C, ASP591A, ASP591C, GLU422A, GLU422C, GLU429A, GLU429C, GLU577A, GLU577C, GLU603A, GLU603C, GLY423A, GLY423C, HIS607A, HIS607C, HIS609A, HIS609C, ILE431A, ILE431C, LEU427A, LEU427C, LEU602A, LEU602C, LEU604A, LEU604C, LEU608A, LEU608C, LYS432A, LYS432C, LYS469A, LYS469C, LYS576A, LYS576C, LYS578A, LYS578C, LYS597A, LYS597C, MET434A, MET434C, PHE433A, PHE433C, PHE600A, PHE600C, SER575A, SER575C, THR430A, THR430C, THR436A, THR436C, TRP438A, TRP438C, TRP601A, TRP601C, TYR420A, TYR593A, TYR593C, VAL426A, VAL426C, VAL598A, VAL598C, VAL605A, VAL605C
• B-C: ALA345C, ARG309C, ARG346C, ARG564B, ARG588B, ARG590B, ASN301C, ASN416C, ASN526B, ASN548B, ASN563B, ASN610C, ASP226C, ASP362C, ASP363C, ASP415C, ASP546B, ASP554B, ASP591B, GLN227C, GLN303C, GLN549B, GLN553B, GLN579B, GLU320C, GLU422C, GLU566B, GLU567B, GLY225C, GLY357C, GLY419C, GLY423C, HIS348C, HIS559B, HIS609C, ILE366C, ILE558B, LEU305C, LEU310C, LEU417C, LEU608C, LYS306C, LYS424C, LYS525B, LYS561B, LYS586B, MET529B, PHE413C, PHE557B, PHE565B, PRO304C, PRO361C, PRO364C, PRO421C, PRO550B, PRO552B, PRO562B, SER223C, SER297C, SER322C, SER524B, SER571B, THR224C, THR308C, THR555B, THR560B, TYR302C, TYR307C, TYR347C, TYR418C, TYR420C, VAL354C, VAL355C, VAL414C, VAL528B, VAL568B, VAL569B, VAL589B
• B-D: ALA439B, ALA439D, ALA595B, ALA595D, ALA599B, ALA599D, ARG428B, ARG428D, ARG441B, ARG441D, ARG590B, ARG594B, ARG594D, ASN443B, ASN443D, ASN574D, ASN592B, ASN592D, ASN596B, ASN596D, ASN610D, ASP425B, ASP425D, ASP437B, ASP437D, ASP440B, ASP440D, ASP442B, ASP442D, ASP591B, ASP591D, GLU422B, GLU422D, GLU429B, GLU429D, GLU577B, GLU577D, GLU603B, GLU603D, GLY423B, GLY423D, HIS607B, HIS607D, HIS609D, ILE431B, ILE431D, LEU427B, LEU427D, LEU602B, LEU602D, LEU604B, LEU604D, LEU608B, LEU608D, LYS432B, LYS432D, LYS469B, LYS469D, LYS576B, LYS576D, LYS578B, LYS578D, LYS597B, LYS597D, MET434B, MET434D, PHE433B, PHE433D, PHE600B, PHE600D, PRO606B, SER575B, SER575D, THR430B, THR430D, THR436B, THR436D, TRP438B, TRP438D, TRP601B, TRP601D, TYR593D, VAL426B, VAL426D, VAL465D, VAL598B, VAL598D, VAL605B, VAL605D
• C-D: ARG564D, ARG588D, ARG590D, ASN375C, ASN526D, ASN563D, ASP377C, GLN285C, GLN370C, GLN475C, GLU257C, GLU281C, GLU372C, GLU566D, GLU567D, GLY282C, GLY371C, HIS278C, ILE275C, LEU374C, LEU585D, LYS286C, LYS525D, LYS556D, LYS586D, PHE373C, PRO256C, PRO477C, PRO587D, SER277C, SER280C, THR544C, TYR376C, TYR474C