3BHH

crystal structure of human calcium/calmodulin-dependent protein kinase iib isoform 1 (camk2b)

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 71
  • Norm. En. per Res.: -1.8629
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	0.0	-4.0595	-4.0595	31	5	0	964	0	10	17
A-C	0.0	-12.0205	-110.143	-122.1635	73	6	4	5025	0	32	36
A-D	-2.3178	0.0	-38.6049	-40.9227	42	2	0	1898	0	27	17
B-C	0.0	-50.8102	-81.4589	-132.2691	71	2	0	4027	4	44	40
B-D	-3.1692	0.0	-38.6391	-41.8083	40	1	1	1880	0	30	19
C-D	0.0	0.0	-0.335	-0.335	5	0	0	40	0	7	7

Interface residues

• A-B: ALA170B, ALA245A, ALA52B, ARG63B, ARG66B, ASN247A, ASN250A, ASP167B, GLN165B, GLN168B, GLN169B, GLN251A, GLN274A, GLN56B, GLU163B, GLU244A, GLU265A, GLU59B, GLY166B, HIS269A, LEU248A, LYS246A, LYS259A, LYS268A, PHE172B, PRO243A, PRO270A, THR242A, TRP171B, VAL164B, VAL278A
• A-C: ALA175C, ALA228A, ALA230A, ARG135C, ARG187A, ARG187C, ARG260A, ARG53C, ARG60C, ASN247A, ASN250A, ASN256A, ASP136C, ASP216A, ASP218A, ASP218C, ASP232A, ASP54C, GLN219A, GLN219C, GLN224A, GLN224C, GLN225A, GLN251A, GLU217C, GLY159C, GLY173C, GLY176C, GLY229A, HIS220A, HIS220C, ILE226A, ILE249A, ILE255A, LEU160C, LEU181C, LEU186C, LEU222A, LEU222C, LEU253A, LEU300C, LEU50C, LYS138C, LYS188A, LYS188C, LYS221A, LYS221C, LYS227A, LYS227C, LYS246A, LYS259A, LYS49C, LYS57C, PHE172C, PHE174C, PHE214A, PHE233A, PRO178C, PRO183A, PRO234A, SER51C, THR177C, THR254A, TRP171C, TRP198A, TRP215A, TRP215C, TRP238A, TYR205A, TYR223A, TYR223C, TYR231A, VAL185C
• A-D: ALA170A, ALA258A, ALA263A, ARG260A, ARG66D, ARG75D, ASP12D, ASP167A, ASP78D, CYS35D, GLN129A, GLN165A, GLN168A, GLN169A, GLU13D, GLU265A, GLU82D, GLY131A, GLY166A, GLY37D, HIS126A, HIS128A, HIS264A, HIS38D, HIS77D, ILE261A, ILE80D, LEU125A, LEU34D, LEU76D, LYS193A, LYS259A, LYS268A, LYS33D, MET10D, MET130A, SER79D, SER81D, THR262A, THR36D, TYR14D, VAL89D
• B-C: ALA145B, ALA152B, ALA230C, ALA62B, ARG297C, ARG298C, ARG63B, ARG66B, ARG75B, ASN72B, ASP216C, ASP218C, ASP232C, ASP239C, ASP78B, ASP91B, CYS290C, CYS35B, CYS65B, GLN129B, GLN165B, GLN225C, GLN285C, GLU163B, GLU217C, GLU237C, GLU286C, GLU289C, GLY131B, GLY166B, GLY210C, GLY37B, HIS126B, HIS283C, HIS38B, HIS70B, HIS77B, ILE64B, ILE73B, LEU222C, LEU67B, LEU68B, LEU92B, LYS154B, LYS221C, LYS292C, LYS293C, LYS33B, LYS69B, MET130B, PHE214C, PHE233C, PHE294C, PRO212C, PRO213C, PRO234C, PRO236C, SER235C, SER71B, SER79B, THR36B, TRP215C, TRP238C, TYR205C, TYR211C, TYR231C, TYR40B, VAL209C, VAL288C, VAL74B, VAL93B
• B-D: ALA52B, ARG29D, ARG53B, ASN46B, ASN46D, ASP12D, ASP19D, ASP54B, GLN15D, GLN56B, GLU18D, GLU59B, GLU82B, GLU82D, GLU83B, GLU83D, GLY84B, GLY84D, HIS55B, ILE44D, ILE80B, LEU16D, LEU34D, LEU50B, LEU58B, LYS48B, LYS48D, LYS49B, MET10B, PHE85B, PHE85D, SER51B, SER81B, THR11D, THR47B, TYR14D, TYR17D, TYR87D, VAL27D, VAL32D
• C-D: ALA296C, ARG297C, GLU82D, GLU83D, LEU300C