3BG9

crystal structure of human pyruvate carboxylase (missing the biotin carboxylase domain at the n-terminus) f1077a mutant

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 205
  • Norm. En. per Res.: -2.1871
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-60.0617	-72.3264	-303.747	-436.1351	205	18	13	15222	11	74	52
A-D	0.0	9.9167	-69.1836	-59.2669	52	2	11	3761	0	10	8
C-D	-67.302	-75.2663	-305.792	-448.3604	205	21	12	15103	11	73	52

Interface residues

• A-B: ALA711A, ALA711B, ALA751A, ALA751B, ALA778A, ALA778B, ALA781A, ALA781B, ALA782A, ALA782B, ALA785A, ALA785B, ALA798A, ALA798B, ALA812A, ALA812B, ALA815A, ALA815B, ALA846A, ALA846B, ALA852A, ALA852B, ARG715A, ARG715B, ARG818A, ARG818B, ARG842A, ARG842B, ASN858A, ASN858B, ASN864A, ASN864B, ASP526A, ASP526B, ASP709A, ASP709B, ASP712A, ASP712B, ASP774A, ASP774B, ASP799A, ASP799B, ASP833A, ASP833B, ASP849A, ASP849B, ASP860A, ASP860B, CYS752A, CYS816A, CYS816B, CYS850A, CYS850B, GLN788A, GLN788B, GLU829A, GLU829B, GLU836A, GLU836B, GLU839A, GLU839B, GLU863A, GLU863B, GLU889A, GLU889B, GLY777A, GLY777B, GLY779A, GLY779B, GLY803A, GLY803B, GLY811A, GLY811B, GLY819A, GLY819B, GLY840A, GLY840B, GLY843A, GLY843B, GLY857A, GLY857B, GLY882A, GLY882B, GLY884A, GLY884B, HIS875A, HIS875B, HIS879A, HIS879B, LEU577A, LEU577B, LEU578A, LEU578B, LEU746A, LEU746B, LEU747A, LEU747B, LEU784A, LEU784B, LEU813A, LEU813B, LEU822A, LEU822B, LEU844A, LEU844B, LEU883A, LEU883B, LYS748A, LYS748B, LYS855A, LYS855B, LYS886A, LYS886B, LYS888A, LYS888B, LYS891A, LYS891B, LYS892A, LYS892B, MET783B, MET801A, MET801B, MET804A, MET804B, MET810A, MET810B, MET828A, MET828B, MET854A, MET854B, PHE832A, PHE832B, PHE887A, PHE887B, PRO524A, PRO524B, PRO530A, PRO530B, PRO713A, PRO713B, PRO749A, PRO749B, PRO808A, PRO808B, PRO821A, PRO821B, SER523A, SER523B, SER714B, SER776A, SER776B, SER800A, SER800B, SER802A, SER802B, SER806A, SER806B, SER809A, SER809B, SER835A, SER835B, SER856A, SER856B, SER859A, SER859B, SER885A, SER885B, THR525A, THR525B, THR750A, THR750B, THR753A, THR775A, THR775B, THR817A, THR817B, THR820A, THR820B, THR851A, THR851B, THR853A, THR853B, TRP838A, TRP838B, TYR593B, TYR834A, TYR834B, TYR837A, TYR837B, TYR845A, TYR845B, TYR862A, TYR862B, TYR871A, TYR871B, VAL528A, VAL528B, VAL780A, VAL780B, VAL814A, VAL814B, VAL831A, VAL831B, VAL861A, VAL861B
• A-D: ALA1045A, ALA1045D, ALA1062A, ALA1062D, ALA1064A, ALA1064D, ALA1077A, ALA1077D, ARG1070A, ARG1070D, ARG1074A, ARG1074D, ARG1085A, ARG1085D, ASN1069A, ASN1069D, ASN1081A, ASN1081D, ASP1067A, ASP1067D, GLN1075A, GLN1075D, GLN1083A, GLN1083D, GLU1079A, GLU1079D, GLY1082A, GLY1082D, ILE1044A, ILE1044D, ILE1087A, ILE1087D, LEU1063A, LEU1063D, LEU1068A, LEU1068D, LEU1084A, LEU1084D, LEU1088A, LEU1088D, LYS1061A, LYS1061D, PHE1078A, PHE1078D, SER1066A, SER1066D, SER1086A, SER1086D, VAL1065A, VAL1065D, VAL1076A, VAL1076D
• C-D: ALA711C, ALA711D, ALA751C, ALA751D, ALA778C, ALA778D, ALA781C, ALA781D, ALA782C, ALA782D, ALA785C, ALA785D, ALA798C, ALA798D, ALA812C, ALA812D, ALA815C, ALA815D, ALA846C, ALA846D, ALA852C, ALA852D, ARG715C, ARG715D, ARG818C, ARG818D, ARG842C, ARG842D, ASN858C, ASN858D, ASN864C, ASN864D, ASP526C, ASP526D, ASP709C, ASP709D, ASP712C, ASP712D, ASP774C, ASP774D, ASP799C, ASP799D, ASP833C, ASP833D, ASP849C, ASP849D, ASP860C, ASP860D, CYS752D, CYS816C, CYS816D, CYS850C, CYS850D, GLN788C, GLN788D, GLU829C, GLU829D, GLU836C, GLU836D, GLU839C, GLU839D, GLU863C, GLU863D, GLU889C, GLU889D, GLY777C, GLY777D, GLY779C, GLY779D, GLY803C, GLY803D, GLY811C, GLY811D, GLY819C, GLY819D, GLY840C, GLY840D, GLY843C, GLY843D, GLY857C, GLY857D, GLY882C, GLY882D, GLY884C, GLY884D, HIS875C, HIS875D, HIS879C, HIS879D, LEU577C, LEU577D, LEU578C, LEU578D, LEU746C, LEU746D, LEU747C, LEU747D, LEU784C, LEU784D, LEU813C, LEU813D, LEU822C, LEU844C, LEU844D, LEU883C, LEU883D, LYS748C, LYS748D, LYS855C, LYS855D, LYS886C, LYS886D, LYS888C, LYS888D, LYS891C, LYS891D, LYS892C, LYS892D, MET783D, MET801C, MET801D, MET804C, MET804D, MET810C, MET810D, MET828C, MET828D, MET854C, MET854D, MET881D, PHE832C, PHE832D, PHE887C, PHE887D, PRO524C, PRO524D, PRO530C, PRO530D, PRO713C, PRO713D, PRO749C, PRO749D, PRO808C, PRO808D, PRO821C, PRO821D, SER523C, SER523D, SER714D, SER776C, SER776D, SER800C, SER800D, SER802C, SER802D, SER806C, SER806D, SER809C, SER809D, SER835C, SER835D, SER856C, SER856D, SER859C, SER859D, SER885C, SER885D, THR525C, THR525D, THR750C, THR750D, THR753C, THR775C, THR775D, THR817C, THR817D, THR820C, THR820D, THR851C, THR851D, THR853C, THR853D, TRP838C, TRP838D, TYR593D, TYR834C, TYR834D, TYR837C, TYR837D, TYR845C, TYR845D, TYR862C, TYR862D, TYR871C, TYR871D, VAL528C, VAL528D, VAL780C, VAL780D, VAL814C, VAL814D, VAL831C, VAL831D, VAL861C, VAL861D