3B63

actin filament model in the extended form of acromsomal bundle in the limulus sperm

• Total interactions analyzed: 91
• Total true interactions: 25
• Strongest Interaction:
  • Chains: L-N
  • Int. Res.: 56
  • Norm. En. per Res.: -3.6801
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-14.0741	-9.1703	-10.6097	-33.8541	45	2	0	1134	0	18	16
A-C	-40.234	-69.978	-140.936	-251.148	76	8	4	5872	7	20	16
B-C	-76.7373	-65.0734	-199.679	-341.4897	105	32	1	9024	6	46	42
B-D	0.0	24.7701	-74.0904	-49.3203	50	0	2	3082	0	14	16
C-D	0.0	6.395	-8.5374	-2.1424	24	0	0	591	0	13	9
C-E	-27.5571	-7.2228	-52.4453	-87.2252	49	5	0	2316	0	16	9
D-E	-34.1879	-11.884	-72.7933	-118.8652	57	5	0	3265	2	24	16
D-F	-18.0768	-12.9177	-118.055	-149.0494	52	12	2	4349	2	21	12
E-F	-72.7353	10.8479	-270.628	-332.5154	105	41	2	10669	0	40	32
E-G	0.0	-11.8695	-92.935	-104.8045	59	4	5	4312	1	20	15
F-G	-18.0183	-0.9159	-136.239	-155.1732	87	15	1	6310	0	29	27
F-H	-8.4109	21.1165	-107.57	-94.8643	47	10	3	4641	0	10	15
G-H	-9.6579	-2.8737	-9.3389	-21.8706	38	1	0	657	1	21	13
G-I	0.0	-16.491	-39.1743	-55.6653	42	1	2	1897	0	11	12
H-I	0.0	-1.1567	-17.0741	-18.2308	36	0	0	947	2	20	15
H-J	-23.4603	12.3222	-134.264	-145.4021	61	13	1	4830	0	24	13
I-J	-49.0532	-14.2331	-350.393	-413.6793	124	41	3	12935	2	45	45
I-K	-13.6199	-49.2217	-140.09	-202.9316	78	9	3	6550	2	31	19
J-K	-24.6373	-55.2999	-104.721	-184.6582	87	7	0	4953	3	37	33
J-L	-32.1846	33.0352	-180.813	-179.9624	72	28	3	6912	2	22	13
K-L	-77.437	-18.2545	-313.294	-408.9856	127	29	1	11371	4	49	38
K-M	-20.2562	12.1806	-90.3722	-98.4478	44	7	1	3540	2	12	10
L-M	-21.4238	-48.3263	-264.257	-334.0071	116	12	2	10230	2	41	28
L-N	-23.0261	-61.1884	-121.87	-206.0845	56	7	1	4797	3	25	18
M-N	-36.1049	-19.5206	-174.634	-230.2595	121	12	0	9268	2	42	39

Interface residues

• A-B: ALA108B, ARG171B, ARG191A, ARG34A, ARG57A, ARG63A, ASN247A, ASP173B, GLU190A, GLU264B, GLU67B, GLY192A, GLY262B, GLY263A, GLY58A, HIS167B, ILE169B, ILE187A, ILE261B, ILE69B, LEU104B, LEU174B, LEU262A, LEU60A, LEU62A, LYS107B, LYS186A, LYS278B, MET170B, MET263B, PHE195A, PHE260B, PRO106B, SER189A, SER194A, SER196A, SER259B, SER265B, THR197A, THR198A, THR61A, THR71B, TYR193A, TYR64A, VAL261A
• A-C: ALA162C, ALA199A, ALA316C, ALA53A, ARG142C, ARG201A, ARG285C, ARG34A, ARG57A, ASP239A, ASP281C, ASP283C, CYS280C, GLN241A, GLN348C, GLN349C, GLN44A, GLN54A, GLU200A, GLU202A, GLU236A, GLU287C, GLU52A, GLY163C, GLY240A, GLY37A, GLY41A, GLY43A, GLY58A, HIS168C, HIS35A, ILE160C, ILE203A, ILE38A, ILE59A, LEU137C, LEU166C, LEU237A, LEU341C, LEU344C, LEU60A, LYS279C, LYS286C, LYS321C, LYS56A, MET278C, MET320C, MET350C, MET39A, MET42A, PHE164C, PHE195A, PHE347C, PRO167C, PRO238A, PRO317C, SER165C, SER196A, SER318C, SER319C, SER55A, THR143C, THR144C, THR197A, THR198A, THR345C, THR346C, TYR138C, TYR161C, TYR289C, TYR48A, VAL134C, VAL242A, VAL282C, VAL284C, VAL40A
• B-C: ALA103C, ALA169C, ALA198B, ALA225B, ALA255C, ALA267C, ALA53B, ARG111C, ARG172C, ARG177B, ARG190B, ARG200B, ARG250B, ARG251C, ARG285C, ARG34B, ARG57B, ASN106C, ASN110C, ASN275C, ASP174C, ASP178B, ASP181B, ASP281C, CYS280C, GLN223C, GLN240B, GLN271C, GLN54B, GLU102C, GLU112C, GLU189B, GLU199B, GLU219C, GLU254C, GLU264B, GLU265C, GLU52B, GLU67C, GLY191B, GLY262B, GLY263C, GLY268C, GLY58B, HIS156C, HIS168C, HIS258C, HIS35B, HIS68C, ILE131C, ILE170C, ILE173C, ILE186B, ILE261B, ILE59B, ILE70C, LEU166C, LEU171C, LEU175C, LEU183B, LEU187B, LEU236B, LEU262C, LEU264C, LEU60B, LEU62B, LYS108C, LYS185B, LYS279C, LYS56B, MET105C, MET184B, MET222C, MET263B, PHE164C, PHE194B, PHE218C, PHE257C, PHE260B, PRO104C, PRO107C, PRO167C, PRO259C, SER109C, SER165C, SER193B, SER260C, SER266C, SER276C, SER55B, THR155C, THR180B, THR188B, THR196B, THR197B, THR243B, THR272C, THR61B, THR72C, TYR182B, TYR192B, VAL154C, VAL157C, VAL195B, VAL261C
• B-D: ALA163D, ALA198B, ALA314D, ARG283D, ARG57B, ASP238B, ASP279D, ASP281D, ASP51B, CYS278D, GLN240B, GLN54B, GLU160D, GLU201B, GLU235B, GLU52B, GLY161D, GLY239B, GLY41B, GLY58B, HIS166D, ILE129D, ILE168D, ILE202B, ILE280D, ILE282D, LEU164D, LEU236B, LEU313D, LYS106D, LYS209B, LYS284D, LYS56B, MET276D, MET318D, MET39B, MET42B, PRO165D, PRO237B, PRO315D, SER316D, SER55B, THR317D, TYR159D, TYR162D, TYR272D, TYR48B, VAL241B, VAL38B, VAL40B
• C-D: ARG283D, ASP279D, GLU190C, GLU200C, GLU263D, GLU265C, GLY263C, HIS166D, ILE280D, LEU262C, LEU264C, LYS186C, LYS277D, MET169D, MET185C, MET262D, MET276D, PHE195C, SER194C, SER196C, SER264D, THR197C, THR198C, TYR183C
• C-E: ALA199C, ARG285E, ARG57C, ASP239C, ASP281E, ASP283E, CYS280E, GLN241C, GLN349E, GLU162E, GLU200C, GLU236C, GLY163E, GLY240C, GLY41C, GLY58C, ILE203C, ILE282E, ILE284E, ILE38C, ILE59C, LEU166E, LEU237C, LEU344E, LYS286E, LYS321E, LYS56C, MET320E, MET350E, MET39C, MET42C, PHE195C, PHE347E, PRO238C, PRO317E, SER194C, SER196C, SER318E, SER345E, SER55C, THR197C, THR198C, THR319E, THR346E, TYR161E, TYR164E, TYR289E, VAL242C, VAL40C
• D-E: ALA109E, ALA169E, ARG111E, ARG172E, ARG189D, ARG249D, ARG285E, ARG56D, ASN106E, ASN110E, ASN245D, ASP174E, ASP281E, CYS280E, GLU112E, GLU188D, GLU230D, GLU246D, GLU263D, GLU265E, GLY190D, GLY244D, GLY261D, GLY57D, HIS168E, ILE170E, ILE185D, ILE243D, ILE260D, ILE282E, ILE58D, ILE70E, ILE71E, LEU105E, LEU186D, LYS108E, LYS184D, LYS279E, LYS55D, MET171E, MET262D, MET264E, MET278E, PHE193D, PHE259D, PRO107E, PRO167E, SER192D, SER258D, SER266E, THR187D, THR195D, THR242D, THR60D, TYR181D, TYR191D, VAL194D
• D-F: ALA197D, ALA316F, ALA52D, ARG285F, ARG33D, ARG56D, ASP237D, ASP281F, ASP283F, ASP287F, ASP50D, CYS280F, GLN35D, GLN43D, GLN53D, GLU162F, GLU198D, GLU200D, GLU51D, GLY30D, GLY42D, GLY57D, ILE201D, ILE277F, ILE282F, ILE284F, ILE58D, LEU166F, LEU288F, LEU315F, LEU59D, LEU61D, LYS286F, LYS321F, LYS55D, MET278F, MET320F, MET41D, PRO317F, PRO32D, SER318F, SER46D, SER54D, THR195D, THR196D, THR319F, THR60D, TYR161F, TYR164F, TYR289F, TYR47D, VAL194D
• E-F: ALA169F, ALA176F, ALA199E, ALA223F, ALA226E, ALA226F, ALA267F, ARG172F, ARG191E, ARG201E, ARG251E, ARG251F, ARG285F, ARG34E, ARG57E, ASN106F, ASN157F, ASN247E, ASN247F, ASN275F, ASP174F, ASP179F, ASP182E, ASP281F, ASP283F, CYS252E, CYS280F, GLN258E, GLN258F, GLU190E, GLU200E, GLU202E, GLU219F, GLU254F, GLU265E, GLU265F, GLU271F, GLU68F, GLY153F, GLY192E, GLY263E, GLY263F, GLY268F, GLY58E, HIS156F, HIS168F, HIS35E, ILE170F, ILE187E, ILE203E, ILE262E, ILE262F, ILE269F, ILE277F, ILE282F, ILE70F, LEU105F, LEU173F, LEU175F, LEU184E, LEU188E, LEU60E, LEU62E, LYS108F, LYS186E, LYS279F, MET171F, MET185E, MET222E, MET222F, MET264E, MET264F, MET278F, PHE195E, PHE218E, PHE218F, PHE261E, PHE261F, PRO107F, PRO167F, PRO259E, PRO259F, SER194E, SER227E, SER260E, SER260F, SER266E, SER266F, SER276F, THR155F, THR181E, THR189E, THR197E, THR198E, THR255E, THR255F, THR272F, THR273F, TYR183E, TYR183F, TYR193E, TYR274F, VAL154F, VAL196E, VAL204E
• E-G: ALA162G, ALA199E, ALA316G, ARG201E, ARG285G, ARG57E, ASP239E, ASP281G, ASP283G, CYS280G, GLN241E, GLN54E, GLU200E, GLU202E, GLU236E, GLY163G, GLY240E, GLY37E, GLY41E, GLY58E, HIS168G, ILE160G, ILE203E, ILE277G, ILE59E, LEU237E, LEU315G, LEU341G, LYS286G, LYS56E, MET278G, MET320G, MET350G, MET39E, MET42E, PHE164G, PHE195E, PHE347G, PRO238E, PRO317G, SER165G, SER194E, SER318G, SER319G, SER55E, THR143G, THR197E, THR198E, TYR138G, TYR161G, TYR274G, TYR289G, VAL134G, VAL196E, VAL242E, VAL282G, VAL284G, VAL38E, VAL40E
• F-G: ALA103G, ALA169G, ALA267G, ALA54F, ARG111G, ARG172G, ARG178F, ARG191F, ARG201F, ARG285G, ARG35F, ARG58F, ASN106G, ASN110G, ASP174G, ASP179F, ASP182F, ASP281G, CYS280G, GLN241F, GLN271G, GLN37F, GLN55F, GLU190F, GLU200F, GLU265F, GLU265G, GLY192F, GLY263F, GLY263G, GLY268G, GLY38F, GLY59F, HIS156G, HIS168G, HIS258G, HIS36F, ILE131G, ILE170G, ILE173G, ILE187F, ILE243F, ILE262F, ILE60F, ILE70G, LEU166G, LEU171G, LEU184F, LEU188F, LEU264G, LEU61F, LEU63F, LYS108G, LYS186F, LYS279G, LYS57F, MET105G, MET185F, MET264F, MET40F, PHE195F, PHE257G, PHE261F, PRO104G, PRO107G, PRO167G, PRO259G, SER109G, SER165G, SER194F, SER260F, SER260G, SER266G, SER56F, THR181F, THR189F, THR197F, THR198F, THR244F, THR272G, TYR183F, TYR193F, VAL196F, VAL261G, VAL282G, VAL39F, VAL41F
• F-H: ALA165H, ALA169H, ALA199F, ARG285H, ASP281H, ASP283H, ASP287H, ASP52F, CYS280H, GLN37F, GLN45F, GLN55F, GLU162H, GLU53F, GLY145H, GLY163H, GLY38F, GLY42F, GLY44F, HIS168H, ILE160H, ILE170H, ILE277H, ILE282H, ILE284H, ILE60F, LEU166H, LEU288H, LYS279H, LYS46F, LYS57F, MET171H, MET278H, MET40F, MET43F, PRO159H, PRO167H, SER276H, SER56F, THR143H, THR144H, THR198F, TYR161H, TYR164H, TYR49F, VAL39F, VAL41F
• G-H: ALA109H, ARG172H, ARG191G, ARG251G, ARG34G, ASN106H, ASN110H, ASP174H, ASP281H, GLU190G, GLU265G, GLU265H, GLY192G, GLY263G, GLY263H, GLY58G, HIS168H, ILE187G, ILE70H, LEU105H, LEU262G, LEU264G, LEU60G, LYS108H, LYS186G, LYS279H, MET222G, MET264H, PRO107H, PRO167H, SER189G, SER194G, SER196G, SER260G, THR197G, THR61G, THR72H, VAL261G
• G-I: ALA162I, ALA199G, ALA316I, ARG285I, ARG57G, ASP239G, ASP281I, ASP283I, GLN241G, GLN44G, GLN54G, GLU200G, GLY163I, GLY240G, GLY37G, GLY41G, GLY43G, GLY58G, HIS168I, ILE203G, ILE38G, ILE59G, LEU166I, LYS56G, MET278I, MET320I, MET350I, MET39G, MET42G, PHE164I, PRO238G, PRO317I, SER318I, SER55G, THR143I, THR144I, TYR138I, TYR161I, TYR274I, VAL282I, VAL284I, VAL40G
• H-I: ARG172I, ARG191H, ARG34H, ARG57H, ASN106I, ASN110I, ASP174I, GLU190H, GLU265I, GLY192H, GLY263I, GLY58H, HIS168I, HIS35H, HIS68I, ILE262H, ILE59H, ILE70I, LEU264I, LEU60H, LEU62H, LYS108I, LYS186H, MET105I, MET185H, PHE195H, PRO107I, SER109I, SER194H, SER260I, THR189H, THR197H, THR61H, THR72I, TYR193H, VAL196H
• H-J: ALA199H, ALA316J, ARG201H, ARG285J, ARG34H, ARG57H, ASP239H, ASP281J, ASP283J, ASP287J, CYS280J, GLN241H, GLN36H, GLN44H, GLU162J, GLU200H, GLU202H, GLU236H, GLY163J, GLY240H, GLY37H, GLY43H, GLY58H, HIS35H, ILE203H, ILE277J, ILE282J, ILE284J, ILE59H, LEU166J, LEU237H, LEU288J, LEU344J, LYS286J, LYS321J, LYS56H, MET278J, MET320J, MET350J, MET39H, PHE195H, PHE347J, PRO238H, PRO317J, SER194H, SER318J, SER345J, SER55H, THR143J, THR197H, THR198H, THR319J, THR346J, TYR161J, TYR164J, TYR274J, TYR289J, VAL196H, VAL242H, VAL38H, VAL40H
• I-J: ALA103J, ALA109J, ALA130J, ALA133J, ALA165J, ALA169J, ALA225I, ALA226I, ALA267J, ALA360J, ARG111J, ARG172J, ARG178I, ARG191I, ARG201I, ARG249I, ARG251I, ARG34I, ARG57I, ASN106J, ASN110J, ASN247I, ASP174J, ASP179I, ASP182I, ASP281J, CYS280J, GLN132J, GLN223I, GLN227I, GLN241I, GLU102J, GLU112J, GLU162J, GLU190I, GLU200I, GLU232I, GLU248I, GLU265I, GLU265J, GLU271J, GLU356J, GLU359J, GLU67J, GLY192I, GLY246I, GLY263I, GLY361J, GLY58I, GLY69J, HIS156J, HIS168J, HIS35I, HIS68J, ILE131J, ILE170J, ILE187I, ILE231I, ILE243I, ILE245I, ILE282J, ILE284J, ILE364J, ILE59I, ILE66J, ILE70J, ILE71J, LEU105J, LEU166J, LEU173J, LEU175I, LEU175J, LEU184I, LEU188I, LEU237I, LEU262I, LEU264I, LEU60I, LYS108J, LYS113J, LYS186I, LYS279J, MET114J, MET171J, MET185I, MET222I, MET264J, PHE195I, PHE250I, PRO104J, PRO107J, PRO167J, PRO362J, SER189I, SER194I, SER196I, SER228I, SER229I, SER234I, SER260I, SER260J, SER266J, SER276J, SER363J, THR101J, THR155J, THR181I, THR197I, THR198I, THR224I, THR244I, THR272J, THR61I, THR72J, TRP74J, TYR161J, TYR183I, TYR193I, VAL129J, VAL134J, VAL154J, VAL158J, VAL261I, VAL365J
• I-K: ALA199I, ALA316K, ALA53I, ARG201I, ARG285K, ARG34I, ARG57I, ASP239I, ASP281K, ASP283K, ASP287K, ASP51I, CYS280K, GLN241I, GLN348K, GLN349K, GLN54I, GLU162K, GLU200I, GLU202I, GLU236I, GLU356K, GLU52I, GLY163K, GLY240I, GLY41I, GLY43I, GLY58I, HIS168K, HIS35I, ILE203I, ILE277K, ILE282K, ILE284K, ILE322K, ILE352K, ILE38I, ILE59I, LEU166K, LEU237I, LEU315K, LEU341K, LEU344K, LEU60I, LYS210I, LYS286K, LYS321K, LYS56I, MET278K, MET320K, MET350K, MET39I, MET42I, PHE195I, PHE347K, PRO238I, PRO317K, SER194I, SER196I, SER318K, SER345K, SER55I, THR143K, THR144K, THR197I, THR198I, THR319K, THR346K, TRP351K, TYR128K, TYR138K, TYR161K, TYR164K, TYR235I, TYR274K, TYR289K, VAL242I, VAL40I
• J-K: ALA109K, ALA165K, ALA169K, ALA199J, ALA267K, ARG172J, ARG172K, ARG178J, ARG191J, ARG201J, ARG251J, ARG285K, ARG34J, ARG57J, ASN106K, ASN110K, ASN247J, ASP174J, ASP174K, ASP179J, ASP182J, ASP281K, CYS280K, GLN258K, GLU190J, GLU265J, GLU265K, GLU67J, GLY192J, GLY263J, GLY263K, GLY58J, HIS168K, HIS35J, HIS68J, HIS68K, ILE170K, ILE187J, ILE262J, ILE282K, ILE284K, ILE59J, ILE70K, LEU105K, LEU166K, LEU173K, LEU175J, LEU175K, LEU180J, LEU60J, LEU62J, LYS108K, LYS186J, LYS279K, MET171K, MET185J, MET222J, MET264J, MET264K, MET278K, PHE195J, PHE218J, PHE261J, PHE261K, PRO104K, PRO107K, PRO167K, PRO259J, PRO259K, SER194J, SER260J, SER260K, SER266J, SER266K, THR181J, THR189J, THR197J, THR198J, THR255J, THR61J, THR72K, TYR161K, TYR164K, TYR183J, TYR193J, TYR274K, VAL196J
• J-L: ALA199J, ALA290L, ALA316L, ARG201J, ARG285L, ARG57J, ASP239J, ASP281L, ASP283L, ASP287L, CYS280L, GLN241J, GLN348L, GLN349L, GLN36J, GLN44J, GLU162L, GLU200J, GLU202J, GLU236J, GLU356L, GLY192J, GLY240J, GLY37J, GLY41J, GLY43J, GLY58J, HIS168L, HIS35J, ILE203J, ILE243J, ILE277L, ILE284L, ILE59J, LEU166L, LEU188J, LEU237J, LEU288L, LEU60J, LYS279L, LYS286L, LYS321L, MET278L, MET320L, MET350L, MET39J, MET42J, PHE195J, PRO238J, PRO317L, SER194J, SER234J, SER318L, SER345L, SER55J, THR144L, THR189J, THR197J, THR198J, THR319L, THR346L, TYR161L, TYR164L, TYR193J, TYR235J, TYR289L, VAL196J, VAL204J, VAL242J, VAL282L, VAL38J, VAL40J
• K-L: ALA103L, ALA109L, ALA165L, ALA169L, ALA225K, ALA226K, ALA53K, ARG111L, ARG172L, ARG178K, ARG178L, ARG191K, ARG201K, ARG249K, ARG251K, ARG34K, ARG57K, ASN106L, ASN110L, ASN247K, ASN73L, ASP174K, ASP174L, ASP179K, ASP182K, ASP281L, CYS252K, CYS267L, CYS280L, GLN241K, GLN258L, GLN36K, GLN54K, GLU102L, GLU112L, GLU190K, GLU200K, GLU248K, GLU254K, GLU265K, GLU265L, GLU271L, GLU67K, GLU67L, GLY153L, GLY192K, GLY246K, GLY263K, GLY263L, GLY268L, GLY31K, GLY361L, GLY58K, GLY69L, HIS156L, HIS168L, HIS35K, HIS68K, HIS68L, ILE131L, ILE170L, ILE187K, ILE262K, ILE29K, ILE59K, ILE70L, LEU105L, LEU166L, LEU171L, LEU175K, LEU180K, LEU184K, LEU188K, LEU262L, LEU60K, LEU62K, LYS108L, LYS113L, LYS186K, LYS279L, LYS56K, LYS63K, MET114L, MET185K, MET222K, MET264K, MET264L, MET278L, PHE195K, PHE250K, PHE257L, PHE261K, PHE261L, PRO104L, PRO107L, PRO167L, PRO253K, PRO259K, PRO259L, PRO33K, PRO362L, SER194K, SER260K, SER260L, SER266L, SER360L, SER363L, THR101L, THR189K, THR197K, THR198K, THR255K, THR61K, THR72L, TRP74L, TRP81L, TYR161L, TYR164L, TYR183K, TYR183L, TYR193K, TYR64K, VAL129L, VAL154L, VAL196K, VAL365L, VAL71L
• K-M: ALA199K, ARG201K, ARG285M, ASP239K, ASP281M, ASP283M, ASP287M, CYS280M, GLN241K, GLN349M, GLU200K, GLU236K, GLY240K, GLY41K, ILE203K, ILE243K, ILE284M, LEU166M, LEU237K, LEU288M, LYS286M, LYS321M, MET278M, MET320M, MET350M, MET39K, PHE195K, PHE347M, PRO238K, PRO317M, SER194K, SER234K, SER318M, THR197K, THR198K, THR319M, THR346M, TYR235K, TYR289M, VAL196K, VAL242K, VAL282M, VAL38K, VAL40K
• L-M: ALA103M, ALA109M, ALA169M, ALA199L, ALA215M, ALA255M, ALA314M, ARG111M, ARG172M, ARG178L, ARG191L, ARG201L, ARG251L, ARG285M, ARG307M, ARG32L, ARG34L, ARG57L, ASN106M, ASN110M, ASN275M, ASP179L, ASP182L, ASP217M, CYS267M, GLN116M, GLN220M, GLN241L, GLN258M, GLN36L, GLN54L, GLU112M, GLU190L, GLU200L, GLU219M, GLU254M, GLU265M, GLU271M, GLU311M, GLU67L, GLY192L, GLY263M, GLY268M, GLY361M, GLY37L, GLY58L, GLY69M, HIS156M, HIS168M, HIS270M, HIS35L, HIS68M, ILE170M, ILE187L, ILE207L, ILE269M, ILE312M, ILE364M, ILE59L, ILE70M, LEU105M, LEU166M, LEU171M, LEU173M, LEU184L, LEU188L, LEU256M, LEU315M, LEU60L, LEU62L, LYS108M, LYS113M, LYS186L, LYS279M, LYS310M, LYS56L, LYS63L, MET185L, MET264M, MET278M, MET39L, MET42L, PHE195L, PHE218M, PHE257M, PHE261M, PHE274M, PRO104M, PRO107M, PRO167M, PRO259M, PRO33L, PRO362M, SER194L, SER260M, SER266M, SER360M, SER363M, SER55L, THR181L, THR189L, THR196L, THR197L, THR198L, THR272M, THR61L, THR72L, TYR183L, TYR193L, TYR64L, VAL154M, VAL204L, VAL282M, VAL365M, VAL38L, VAL40L
• L-N: ALA199L, ALA314N, ALA316N, ARG201L, ARG205L, ARG285N, ARG57L, ASP206L, ASP239L, ASP281N, ASP283N, CYS280N, GLN241L, GLN309N, GLN54L, GLU162N, GLU200L, GLU202L, GLU236L, GLU311N, GLY240L, GLY58L, ILE203L, ILE207L, ILE243L, ILE282N, ILE284N, ILE312N, ILE322N, LEU166N, LEU237L, LEU315N, LEU62L, LYS210L, LYS286N, LYS310N, LYS321N, LYS56L, MET278N, MET320N, PHE195L, PRO238L, PRO317N, SER194L, SER318N, SER55L, THR197L, THR198L, THR313N, THR319N, TYR161N, TYR193L, TYR235L, TYR274N, TYR289N, VAL204L
• M-N: ALA109N, ALA165N, ALA169N, ALA176M, ALA267N, ALA53M, ARG111N, ARG172M, ARG172N, ARG178M, ARG191M, ARG201M, ARG251M, ARG251N, ARG285N, ARG32M, ARG34M, ARG57M, ASN106N, ASN110N, ASN247N, ASN275N, ASP174M, ASP174N, ASP179M, ASP182M, ASP281N, ASP283N, CYS280N, GLN258N, GLN36M, GLN54M, GLU112N, GLU190M, GLU190N, GLU248N, GLU254N, GLU265M, GLU265N, GLU271N, GLU67M, GLU67N, GLY153M, GLY192M, GLY263M, GLY263N, GLY268N, GLY31M, GLY37M, GLY58M, HIS168N, HIS270N, HIS35M, HIS68M, HIS68N, ILE170N, ILE187M, ILE187N, ILE262N, ILE282N, ILE284N, ILE29M, ILE59M, ILE70M, ILE70N, LEU105N, LEU166N, LEU175M, LEU188M, LEU262M, LEU315N, LEU60M, LEU62M, LYS108N, LYS113N, LYS186M, LYS186N, LYS279N, LYS56M, LYS63M, MET171N, MET185M, MET222N, MET264M, MET264N, MET278N, MET39M, PHE195M, PHE218N, PHE250N, PHE261M, PHE261N, PRO107N, PRO167N, PRO259M, PRO259N, PRO33M, SER194M, SER260M, SER260N, SER266M, SER266N, SER276N, SER363N, THR189M, THR196M, THR197M, THR255N, THR61M, THR72M, THR72N, TYR161N, TYR164N, TYR183M, TYR183N, TYR193M, TYR274N, TYR64M, VAL154M, VAL30M, VAL38M