3B5N

structure of the yeast plasma membrane snare complex

• Total interactions analyzed: 66
• Total true interactions: 32
• Strongest Interaction:
  • Chains: A-D
  • Int. Res.: 118
  • Norm. En. per Res.: -4.1358
• Hub Node: A(7)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-30.8285	-20.0409	-416.003	-466.8724	122	10	20	16349	3	41	45
A-C	0.0	0.0	-35.6403	-35.6403	51	0	1	2045	0	3	7
A-D	-28.7703	-117.2086	-342.051	-488.0299	118	14	15	14281	7	36	38
A-E	0.0	0.0	-0.1201	-0.1201	7	0	0	31	0	5	0
A-H	0.0	0.0	-1.9078	-1.9078	11	0	0	147	0	5	0
A-K	0.0	-35.7952	-22.305	-58.1002	21	5	1	1020	2	11	4
A-L	-35.9608	-26.4845	-21.0618	-83.5071	22	3	0	803	2	11	7
B-C	-36.3674	-32.5054	-472.35	-541.2228	139	14	16	18113	3	31	33
B-D	-9.3807	0.0	-52.8835	-62.2642	64	0	1	3304	4	9	8
B-I	0.0	0.0	-0.0109	-0.0109	2	0	0	1	0	0	5
B-L	-11.436	-21.4258	-10.1915	-43.0533	19	1	0	504	1	8	6
C-D	-60.6562	-103.7802	-357.152	-521.5884	129	13	12	14979	7	33	19
C-E	0.0	9.4692	-0.1829	9.2863	7	0	0	42	0	5	5
C-F	0.0	0.0	-0.065	-0.065	4	0	0	34	0	3	5
D-E	-17.0644	-21.4201	-31.3818	-69.8663	23	3	0	1105	1	11	13
D-F	0.0	0.0	-0.0066	-0.0066	2	0	0	5	0	0	3
D-G	0.0	0.0	-0.0003	-0.0003	2	0	0	1	0	0	0
D-H	-7.7619	-11.6737	-22.2153	-41.6509	20	2	0	905	2	7	8
D-K	0.0	0.0	-0.0517	-0.0517	7	0	0	19	0	0	0
D-L	0.0	0.0	-0.0003	-0.0003	2	0	0	1	0	1	2
E-F	-18.4417	-23.2837	-401.233	-442.9584	119	9	20	15967	4	43	42
E-G	0.0	0.0	-31.0141	-31.0141	59	0	1	1966	0	3	7
E-H	-62.4541	-82.8258	-274.999	-420.2789	111	15	13	12746	7	29	35
F-G	-17.7684	-38.5912	-463.746	-520.1056	137	6	16	17794	5	29	31
F-H	-9.5159	0.0	-50.663	-60.1789	59	0	1	3129	4	9	7
G-H	-66.5605	-125.2899	-337.837	-529.6874	129	18	12	15088	8	33	20
I-J	-20.5964	-3.4796	-361.592	-385.668	115	16	20	15071	3	41	42
I-K	0.0	0.0	-28.605	-28.605	55	0	1	1846	0	3	5
I-L	-39.3235	-64.5027	-308.912	-412.7382	111	15	13	12734	5	33	36
J-K	-31.3319	-9.5007	-412.495	-453.3277	129	15	12	16126	1	29	29
J-L	0.0	-9.3973	-41.028	-50.4253	61	3	1	3187	0	9	8
K-L	-47.8066	-87.3144	-334.604	-469.7249	125	21	11	14339	6	32	21

Interface residues

• A-B: ALA208B, ALA238B, ALA252B, ALA256B, ALA30A, ALA34A, ALA51A, ALA64A, ALA68A, ALA71A, ALA78A, ALA84A, ARG196B, ARG257B, ARG28A, ARG44A, ARG53A, ARG56A, ARG76A, ARG80A, ARG82A, ASN215B, ASN227B, ASN234B, ASN46A, ASN48A, ASN66A, ASN79A, ASP216B, ASP229B, ASP232B, ASP237B, ASP241B, ASP250B, ASP37A, ASP38A, ASP45A, ASP62A, ASP65A, GLN198B, GLN212B, GLN224B, GLN225B, GLN239B, GLN244B, GLN33A, GLN72A, GLU199B, GLU204B, GLU209B, GLU218B, GLU219B, GLU223B, GLU226B, GLU236B, GLU243B, GLU31A, GLU35A, GLU52A, GLU55A, GLU61A, GLY245B, GLY247B, GLY26A, GLY41A, GLY54A, GLY73A, GLY77A, HIS248B, ILE222B, ILE231B, ILE36A, ILE42A, ILE47A, ILE60A, LEU200B, LEU201B, LEU203B, LEU210B, LEU213B, LEU220B, LEU240B, LEU32A, LEU57A, LEU67A, LYS202B, LYS205B, LYS233B, LYS251B, LYS254B, LYS49A, LYS63A, LYS75A, LYS83A, MET207B, MET217B, MET43A, MET85A, PHE214B, PHE74A, SER206B, SER255B, SER27A, SER59A, SER70A, THR211B, THR249B, THR29A, THR39A, THR58A, TRP86A, VAL221B, VAL228B, VAL230B, VAL235B, VAL242B, VAL246B, VAL253B, VAL40A, VAL50A, VAL69A, VAL81A
• A-C: ALA451C, ALA454C, ALA457C, ALA489C, ALA64A, ALA68A, ALA71A, ALA78A, ALA84A, ARG53A, ARG82A, ASN46A, ASN478C, ASN486C, ASP490C, GLN468C, GLN471C, GLN485C, GLN500C, GLY458C, GLY466C, HIS467C, ILE36A, ILE60A, LEU32A, LEU462C, LEU465C, LEU472C, LEU479C, LEU496C, LEU499C, LEU57A, LEU67A, LYS492C, LYS497C, MET43A, MET464C, MET482C, MET85A, PHE74A, SER469C, THR29A, THR39A, THR444C, THR447C, THR461C, VAL475C, VAL488C, VAL493C, VAL50A, VAL81A
• A-D: ALA30A, ALA34A, ALA51A, ALA612D, ALA648D, ALA64A, ALA68A, ALA71A, ALA78A, ALA84A, ARG28A, ARG44A, ARG53A, ARG56A, ARG596D, ARG607D, ARG625D, ARG646D, ARG76A, ARG80A, ARG82A, ASN46A, ASN48A, ASN597D, ASN606D, ASN627D, ASN628D, ASN639D, ASN643D, ASN645D, ASN66A, ASN79A, ASP37A, ASP38A, ASP45A, ASP595D, ASP599D, ASP620D, ASP62A, ASP634D, ASP635D, ASP637D, ASP65A, GLN33A, GLN600D, GLN602D, GLN603D, GLN622D, GLN623D, GLN72A, GLU31A, GLU35A, GLU52A, GLU55A, GLU593D, GLU618D, GLU61A, GLU630D, GLU631D, GLY26A, GLY41A, GLY54A, GLY616D, GLY649D, GLY73A, GLY77A, HIS641D, ILE36A, ILE42A, ILE47A, ILE594D, ILE601D, ILE60A, ILE629D, ILE638D, ILE650D, LEU32A, LEU57A, LEU592D, LEU598D, LEU608D, LEU613D, LEU619D, LEU626D, LEU636D, LEU640D, LEU647D, LEU67A, LYS49A, LYS609D, LYS610D, LYS617D, LYS624D, LYS63A, LYS75A, MET43A, MET611D, MET642D, MET85A, PHE74A, SER27A, SER59A, SER605D, SER621D, SER632D, SER70A, THR29A, THR39A, THR58A, THR614D, THR615D, THR633D, THR644D, VAL40A, VAL50A, VAL604D, VAL69A, VAL81A
• A-E: ALA34A, ARG76E, ARG80E, ASP38A, ASP45A, LYS49A, VAL69E
• A-H: ALA34A, ALA648H, ASN645H, ASP38A, GLU31A, GLU35A, GLY649H, HIS641H, ILE42A, ILE650H, LYS49A
• A-K: ALA84A, ARG76A, ARG80A, ASN473K, ASN474K, ASN478K, ASP480K, GLN72A, GLU470K, GLU476K, GLY477K, GLY73A, GLY77A, LEU472K, LEU479K, LEU481K, LYS83A, SER469K, VAL475K, VAL484K, VAL81A
• A-L: ALA64A, ALA68A, ARG625L, ARG76A, ARG80A, ASN66A, ASP62A, ASP65A, GLN72A, GLU618L, GLU61A, LEU613L, LEU67A, LYS609L, LYS610L, LYS617L, LYS63A, SER59A, SER621L, THR58A, THR614L, VAL69A
• B-C: ALA189B, ALA191B, ALA195B, ALA208B, ALA238B, ALA252B, ALA256B, ALA442C, ALA451C, ALA454C, ALA457C, ALA489C, ALA494C, ARG196B, ARG257B, ARG445C, ARG456C, ASN215B, ASN227B, ASN234B, ASN446C, ASN460C, ASN473C, ASN474C, ASN478C, ASN486C, ASP216B, ASP229B, ASP232B, ASP237B, ASP241B, ASP250B, ASP453C, ASP480C, ASP490C, GLN194B, GLN198B, GLN212B, GLN224B, GLN225B, GLN239B, GLN244B, GLN438C, GLN452C, GLN468C, GLN471C, GLN485C, GLN500C, GLU192B, GLU199B, GLU204B, GLU209B, GLU218B, GLU219B, GLU223B, GLU226B, GLU236B, GLU243B, GLU455C, GLU470C, GLU476C, GLU491C, GLU495C, GLY245B, GLY247B, GLY431C, GLY458C, GLY463C, GLY466C, GLY477C, HIS197B, HIS248B, HIS467C, ILE222B, ILE231B, ILE433C, LEU190B, LEU200B, LEU201B, LEU203B, LEU210B, LEU213B, LEU220B, LEU240B, LEU448C, LEU462C, LEU465C, LEU472C, LEU479C, LEU481C, LEU496C, LEU499C, LYS202B, LYS205B, LYS233B, LYS251B, LYS254B, LYS434C, LYS437C, LYS449C, LYS483C, LYS487C, LYS492C, LYS497C, LYS498C, MET207B, MET217B, MET450C, MET459C, MET464C, MET482C, PHE214B, PHE435C, SER206B, SER255B, SER432C, SER439C, SER440C, SER443C, SER469C, THR211B, THR249B, THR436C, THR444C, THR447C, THR461C, VAL193B, VAL221B, VAL228B, VAL230B, VAL235B, VAL242B, VAL246B, VAL253B, VAL441C, VAL475C, VAL484C, VAL488C, VAL493C
• B-D: ALA238B, ALA252B, ALA256B, ALA612D, ARG196B, ARG607D, ASN227B, ASN234B, ASN597D, ASN606D, ASN643D, ASP241B, ASP595D, ASP637D, GLN224B, GLN239B, GLN602D, GLN622D, GLU199B, GLU204B, GLU243B, GLU591D, GLU630D, GLY245B, GLY616D, HIS197B, HIS248B, ILE231B, ILE594D, ILE601D, ILE629D, ILE650D, LEU200B, LEU203B, LEU210B, LEU592D, LEU598D, LEU608D, LEU613D, LEU619D, LEU626D, LEU636D, LEU640D, LEU647D, LYS609D, LYS610D, MET207B, MET217B, MET590D, MET611D, PHE214B, SER605D, THR211B, THR249B, THR615D, THR633D, VAL193B, VAL221B, VAL228B, VAL235B, VAL242B, VAL246B, VAL253B, VAL604D
• B-I: GLU223B, GLU35I
• B-L: ARG607L, ASN227B, ASN234B, ASN606L, ASP229B, ASP599L, GLN224B, GLN225B, GLN602L, GLN603L, GLU219B, GLU223B, GLU226B, LEU220B, LYS610L, LYS617L, THR614L, VAL228B, VAL230B
• C-D: ALA442C, ALA451C, ALA454C, ALA457C, ALA489C, ALA494C, ALA612D, ALA648D, ARG445C, ARG456C, ARG596D, ARG607D, ARG625D, ARG646D, ASN446C, ASN460C, ASN473C, ASN474C, ASN478C, ASN486C, ASN597D, ASN606D, ASN628D, ASN639D, ASN643D, ASN645D, ASP453C, ASP480C, ASP490C, ASP595D, ASP599D, ASP620D, ASP634D, ASP635D, ASP637D, GLN438C, GLN452C, GLN468C, GLN471C, GLN485C, GLN500C, GLN600D, GLN602D, GLN603D, GLN622D, GLN623D, GLU455C, GLU470C, GLU476C, GLU491C, GLU495C, GLU589D, GLU591D, GLU593D, GLU618D, GLU630D, GLU631D, GLY458C, GLY466C, GLY477C, GLY587D, GLY616D, GLY649D, HIS467C, HIS641D, ILE433C, ILE594D, ILE601D, ILE629D, ILE638D, ILE650D, LEU448C, LEU462C, LEU465C, LEU472C, LEU479C, LEU481C, LEU496C, LEU499C, LEU592D, LEU598D, LEU608D, LEU613D, LEU619D, LEU626D, LEU636D, LEU640D, LEU647D, LYS434C, LYS437C, LYS449C, LYS483C, LYS487C, LYS492C, LYS497C, LYS498C, LYS610D, LYS617D, LYS624D, MET450C, MET459C, MET464C, MET482C, MET590D, MET611D, MET642D, PHE435C, SER439C, SER440C, SER443C, SER469C, SER588D, SER605D, SER621D, SER632D, THR436C, THR444C, THR447C, THR461C, THR614D, THR615D, THR633D, THR644D, VAL441C, VAL475C, VAL484C, VAL488C, VAL493C, VAL604D
• C-E: ALA51E, ASP480C, GLU55E, LYS483C, LYS487C, THR58E, VAL484C
• C-F: LEU220F, LYS205F, LYS487C, LYS498C
• D-E: ALA64E, ALA68E, ARG625D, ASN627D, ASN628D, ASN66E, ASP620D, ASP62E, ASP65E, GLN622D, GLN623D, GLU61E, GLU631D, LEU67E, LYS617D, LYS624D, LYS63E, SER59E, SER621D, SER632D, SER70E, THR58E, VAL69E
• D-F: ASN234F, LYS624D
• D-G: LYS497G, LYS610D
• D-H: ALA648H, ARG646H, ASN639H, ASN645H, ASP620D, ASP634H, ASP637H, GLY649H, HIS641H, ILE638H, ILE650H, LEU613D, LEU636H, LEU640H, LYS609D, LYS610D, LYS617D, MET642H, THR614D, THR644H
• D-K: ALA648D, ASP480K, GLY649D, ILE650D, LYS483K, LYS487K, VAL484K
• D-L: HIS641D, LYS624L
• E-F: ALA195F, ALA208F, ALA238F, ALA252F, ALA256F, ALA30E, ALA34E, ALA51E, ALA64E, ALA68E, ALA71E, ALA78E, ALA84E, ARG196F, ARG44E, ARG53E, ARG56E, ARG76E, ARG80E, ARG82E, ASN215F, ASN227F, ASN234F, ASN46E, ASN48E, ASN66E, ASN79E, ASP216F, ASP229F, ASP232F, ASP237F, ASP241F, ASP250F, ASP37E, ASP38E, ASP45E, ASP62E, ASP65E, GLN198F, GLN212F, GLN224F, GLN225F, GLN239F, GLN244F, GLN33E, GLN72E, GLU199F, GLU204F, GLU209F, GLU218F, GLU219F, GLU223F, GLU226F, GLU236F, GLU243F, GLU31E, GLU35E, GLU52E, GLU55E, GLU61E, GLY245F, GLY247F, GLY41E, GLY54E, GLY73E, GLY77E, HIS248F, ILE222F, ILE231F, ILE36E, ILE42E, ILE47E, ILE60E, LEU200F, LEU201F, LEU203F, LEU210F, LEU213F, LEU220F, LEU240F, LEU32E, LEU57E, LEU67E, LYS202F, LYS205F, LYS233F, LYS251F, LYS254F, LYS49E, LYS63E, LYS75E, LYS83E, MET207F, MET217F, MET43E, MET85E, PHE214F, PHE74E, SER206F, SER255F, SER59E, SER70E, THR211F, THR249F, THR29E, THR39E, THR58E, TRP86E, VAL221F, VAL228F, VAL230F, VAL235F, VAL242F, VAL246F, VAL253F, VAL40E, VAL50E, VAL69E, VAL81E
• E-G: ALA451G, ALA454G, ALA457G, ALA489G, ALA64E, ALA68E, ALA71E, ALA78E, ALA84E, ARG53E, ARG80E, ARG82E, ASN46E, ASN478G, ASN486G, ASP490G, GLN33E, GLN468G, GLN471G, GLN485G, GLU470G, GLY458G, GLY466G, GLY77E, HIS467G, ILE36E, ILE47E, ILE60E, LEU32E, LEU462G, LEU465G, LEU472G, LEU479G, LEU496G, LEU499G, LEU57E, LEU67E, LYS483G, LYS492G, LYS497G, LYS63E, MET43E, MET450G, MET464G, MET482G, MET85E, PHE74E, SER469G, SER70E, THR29E, THR39E, THR444G, THR447G, THR461G, VAL475G, VAL488G, VAL493G, VAL50E, VAL81E
• E-H: ALA30E, ALA34E, ALA51E, ALA612H, ALA648H, ALA64E, ALA68E, ALA71E, ALA78E, ALA84E, ARG44E, ARG53E, ARG56E, ARG607H, ARG625H, ARG646H, ARG76E, ARG80E, ARG82E, ASN46E, ASN48E, ASN597H, ASN606H, ASN627H, ASN628H, ASN639H, ASN643H, ASN645H, ASN66E, ASN79E, ASP37E, ASP38E, ASP45E, ASP599H, ASP620H, ASP62E, ASP634H, ASP635H, ASP637H, ASP65E, GLN33E, GLN600H, GLN602H, GLN603H, GLN622H, GLN623H, GLN72E, GLU31E, GLU35E, GLU52E, GLU55E, GLU618H, GLU61E, GLU630H, GLU631H, GLY41E, GLY54E, GLY616H, GLY649H, GLY73E, GLY77E, HIS641H, ILE36E, ILE42E, ILE47E, ILE594H, ILE601H, ILE60E, ILE629H, ILE638H, ILE650H, LEU32E, LEU57E, LEU598H, LEU608H, LEU613H, LEU619H, LEU626H, LEU636H, LEU640H, LEU647H, LEU67E, LYS49E, LYS609H, LYS610H, LYS617H, LYS624H, LYS63E, LYS75E, MET43E, MET611H, MET642H, MET85E, PHE74E, SER59E, SER605H, SER621H, SER632H, SER70E, THR29E, THR39E, THR58E, THR614H, THR615H, THR633H, THR644H, VAL40E, VAL50E, VAL604H, VAL69E, VAL81E
• F-G: ALA189F, ALA191F, ALA195F, ALA208F, ALA238F, ALA252F, ALA256F, ALA442G, ALA451G, ALA454G, ALA457G, ALA489G, ALA494G, ARG196F, ARG445G, ARG456G, ASN215F, ASN227F, ASN234F, ASN446G, ASN460G, ASN473G, ASN474G, ASN478G, ASN486G, ASP216F, ASP229F, ASP232F, ASP237F, ASP241F, ASP250F, ASP453G, ASP480G, ASP490G, GLN194F, GLN198F, GLN212F, GLN224F, GLN225F, GLN239F, GLN244F, GLN438G, GLN452G, GLN468G, GLN471G, GLN485G, GLU192F, GLU199F, GLU204F, GLU209F, GLU218F, GLU219F, GLU223F, GLU226F, GLU236F, GLU243F, GLU455G, GLU470G, GLU476G, GLU491G, GLU495G, GLY245F, GLY247F, GLY431G, GLY458G, GLY463G, GLY466G, GLY477G, HIS197F, HIS248F, HIS467G, ILE222F, ILE231F, ILE433G, LEU190F, LEU200F, LEU201F, LEU203F, LEU210F, LEU213F, LEU220F, LEU240F, LEU448G, LEU462G, LEU465G, LEU472G, LEU479G, LEU481G, LEU496G, LEU499G, LYS202F, LYS205F, LYS233F, LYS251F, LYS254F, LYS434G, LYS437G, LYS449G, LYS483G, LYS487G, LYS492G, LYS497G, LYS498G, MET207F, MET217F, MET450G, MET459G, MET464G, MET482G, PHE214F, PHE435G, SER206F, SER255F, SER432G, SER439G, SER440G, SER443G, SER469G, THR211F, THR249F, THR436G, THR444G, THR447G, THR461G, VAL193F, VAL221F, VAL228F, VAL230F, VAL235F, VAL242F, VAL246F, VAL253F, VAL441G, VAL475G, VAL484G, VAL488G, VAL493G
• F-H: ALA238F, ALA252F, ALA612H, ARG196F, ARG607H, ASN597H, ASN606H, ASN643H, ASP241F, ASP595H, GLN224F, GLN239F, GLN602H, GLN622H, GLU199F, GLU204F, GLU243F, GLU591H, GLY245F, GLY616H, HIS197F, HIS248F, ILE231F, ILE594H, ILE601H, ILE629H, ILE650H, LEU200F, LEU203F, LEU210F, LEU592H, LEU598H, LEU608H, LEU613H, LEU619H, LEU626H, LEU636H, LEU640H, LEU647H, LYS609H, LYS610H, MET207F, MET217F, MET590H, MET611H, PHE214F, SER605H, THR211F, THR249F, THR615H, THR633H, VAL193F, VAL221F, VAL228F, VAL235F, VAL242F, VAL246F, VAL253F, VAL604H
• G-H: ALA442G, ALA451G, ALA454G, ALA457G, ALA489G, ALA494G, ALA612H, ALA648H, ARG445G, ARG456G, ARG596H, ARG607H, ARG625H, ARG646H, ASN446G, ASN460G, ASN473G, ASN474G, ASN478G, ASN486G, ASN597H, ASN606H, ASN627H, ASN628H, ASN639H, ASN643H, ASN645H, ASP453G, ASP480G, ASP490G, ASP595H, ASP599H, ASP620H, ASP634H, ASP635H, ASP637H, GLN438G, GLN452G, GLN468G, GLN471G, GLN485G, GLN600H, GLN602H, GLN603H, GLN622H, GLN623H, GLU455G, GLU470G, GLU476G, GLU491G, GLU495G, GLU589H, GLU591H, GLU593H, GLU618H, GLU630H, GLU631H, GLY431G, GLY458G, GLY463G, GLY466G, GLY477G, GLY616H, GLY649H, HIS467G, HIS641H, ILE433G, ILE594H, ILE601H, ILE629H, ILE650H, LEU448G, LEU462G, LEU465G, LEU472G, LEU479G, LEU481G, LEU496G, LEU499G, LEU592H, LEU598H, LEU608H, LEU613H, LEU619H, LEU626H, LEU636H, LEU640H, LEU647H, LYS434G, LYS437G, LYS449G, LYS483G, LYS487G, LYS492G, LYS497G, LYS498G, LYS610H, LYS617H, LYS624H, MET450G, MET459G, MET464G, MET482G, MET590H, MET611H, MET642H, PHE435G, SER439G, SER440G, SER443G, SER469G, SER588H, SER605H, SER621H, SER632H, THR436G, THR444G, THR447G, THR461G, THR614H, THR615H, THR633H, THR644H, VAL441G, VAL475G, VAL484G, VAL488G, VAL493G, VAL604H
• I-J: ALA208J, ALA238J, ALA252J, ALA30I, ALA34I, ALA51I, ALA64I, ALA68I, ALA71I, ALA78I, ARG196J, ARG44I, ARG53I, ARG56I, ARG76I, ARG80I, ARG82I, ASN215J, ASN227J, ASN234J, ASN46I, ASN48I, ASN66I, ASN79I, ASP216J, ASP229J, ASP232J, ASP237J, ASP241J, ASP250J, ASP37I, ASP38I, ASP45I, ASP62I, ASP65I, GLN198J, GLN212J, GLN224J, GLN225J, GLN239J, GLN244J, GLN33I, GLN72I, GLU199J, GLU204J, GLU209J, GLU218J, GLU219J, GLU223J, GLU226J, GLU236J, GLU243J, GLU31I, GLU35I, GLU52I, GLU55I, GLU61I, GLY245J, GLY247J, GLY41I, GLY54I, GLY73I, GLY77I, HIS248J, ILE222J, ILE231J, ILE36I, ILE42I, ILE47I, ILE60I, LEU200J, LEU201J, LEU203J, LEU210J, LEU213J, LEU220J, LEU240J, LEU32I, LEU57I, LEU67I, LYS202J, LYS205J, LYS233J, LYS251J, LYS254J, LYS49I, LYS63I, LYS75I, LYS83I, MET207J, MET217J, MET43I, MET85I, PHE214J, PHE74I, SER206J, SER59I, SER70I, THR211J, THR249J, THR29I, THR39I, THR58I, TRP86I, VAL221J, VAL228J, VAL230J, VAL235J, VAL242J, VAL246J, VAL253J, VAL40I, VAL50I, VAL69I, VAL81I
• I-K: ALA451K, ALA454K, ALA457K, ALA489K, ALA64I, ALA68I, ALA71I, ALA78I, ARG53I, ARG82I, ASN46I, ASN478K, ASN486K, ASP490K, GLN33I, GLN468K, GLN471K, GLN485K, GLY458K, GLY466K, GLY77I, HIS467K, ILE36I, ILE47I, ILE60I, LEU32I, LEU462K, LEU465K, LEU472K, LEU479K, LEU496K, LEU57I, LEU67I, LYS483K, LYS492K, LYS498K, LYS63I, MET43I, MET450K, MET464K, MET482K, MET85I, PHE74I, SER469K, SER70I, THR29I, THR39I, THR444K, THR447K, THR461K, VAL475K, VAL488K, VAL493K, VAL50I, VAL81I
• I-L: ALA30I, ALA34I, ALA51I, ALA612L, ALA648L, ALA64I, ALA68I, ALA71I, ALA78I, ALA84I, ARG44I, ARG53I, ARG56I, ARG607L, ARG625L, ARG646L, ARG76I, ARG80I, ARG82I, ASN46I, ASN48I, ASN597L, ASN606L, ASN627L, ASN628L, ASN639L, ASN643L, ASN645L, ASN66I, ASN79I, ASP37I, ASP38I, ASP45I, ASP595L, ASP599L, ASP620L, ASP62I, ASP634L, ASP635L, ASP637L, ASP65I, GLN33I, GLN600L, GLN602L, GLN603L, GLN622L, GLN623L, GLN72I, GLU31I, GLU35I, GLU52I, GLU55I, GLU618L, GLU61I, GLU630L, GLU631L, GLY41I, GLY54I, GLY616L, GLY649L, GLY73I, GLY77I, HIS641L, ILE36I, ILE42I, ILE47I, ILE594L, ILE601L, ILE60I, ILE629L, ILE638L, LEU32I, LEU57I, LEU598L, LEU608L, LEU613L, LEU619L, LEU626L, LEU636L, LEU640L, LEU647L, LEU67I, LYS49I, LYS609L, LYS610L, LYS617L, LYS624L, LYS63I, LYS75I, MET43I, MET611L, MET642L, MET85I, PHE74I, SER59I, SER605L, SER621L, SER632L, SER70I, THR29I, THR39I, THR58I, THR614L, THR615L, THR633L, THR644L, VAL40I, VAL50I, VAL604L, VAL69I, VAL81I
• J-K: ALA191J, ALA195J, ALA208J, ALA238J, ALA252J, ALA442K, ALA451K, ALA454K, ALA457K, ALA489K, ALA494K, ARG196J, ARG445K, ARG456K, ASN215J, ASN227J, ASN234J, ASN446K, ASN460K, ASN473K, ASN474K, ASN478K, ASN486K, ASP216J, ASP229J, ASP232J, ASP237J, ASP241J, ASP250J, ASP453K, ASP480K, ASP490K, GLN194J, GLN198J, GLN212J, GLN224J, GLN225J, GLN239J, GLN244J, GLN438K, GLN452K, GLN468K, GLN471K, GLN485K, GLU192J, GLU199J, GLU204J, GLU209J, GLU218J, GLU219J, GLU223J, GLU226J, GLU236J, GLU243J, GLU455K, GLU470K, GLU476K, GLU491K, GLU495K, GLY245J, GLY247J, GLY458K, GLY463K, GLY466K, GLY477K, HIS197J, HIS248J, HIS467K, ILE222J, ILE231J, LEU200J, LEU201J, LEU203J, LEU210J, LEU213J, LEU220J, LEU240J, LEU448K, LEU462K, LEU465K, LEU472K, LEU479K, LEU481K, LEU496K, LYS202J, LYS205J, LYS233J, LYS251J, LYS254J, LYS434K, LYS437K, LYS449K, LYS483K, LYS487K, LYS492K, LYS497K, LYS498K, MET207J, MET217J, MET450K, MET459K, MET464K, MET482K, PHE214J, PHE435K, SER206J, SER439K, SER440K, SER443K, SER469K, THR211J, THR249J, THR436K, THR444K, THR447K, THR461K, VAL193J, VAL221J, VAL228J, VAL230J, VAL235J, VAL242J, VAL246J, VAL253J, VAL441K, VAL475K, VAL484K, VAL488K, VAL493K
• J-L: ALA238J, ALA252J, ALA612L, ARG196J, ARG607L, ASN227J, ASN597L, ASN606L, ASN639L, ASN643L, ASP241J, ASP595L, GLN224J, GLN239J, GLN602L, GLN622L, GLN623L, GLU199J, GLU204J, GLU243J, GLU591L, GLU630L, GLY245J, GLY616L, HIS197J, HIS248J, ILE231J, ILE594L, ILE601L, ILE629L, LEU200J, LEU203J, LEU210J, LEU598L, LEU608L, LEU613L, LEU619L, LEU626L, LEU636L, LEU640L, LEU647L, LYS609L, LYS610L, MET207J, MET217J, MET590L, MET611L, PHE214J, SER588L, SER605L, THR211J, THR249J, THR615L, THR633L, VAL193J, VAL221J, VAL228J, VAL235J, VAL242J, VAL246J, VAL604L
• K-L: ALA442K, ALA451K, ALA454K, ALA457K, ALA489K, ALA494K, ALA612L, ALA648L, ARG445K, ARG456K, ARG596L, ARG607L, ARG625L, ARG646L, ASN446K, ASN460K, ASN473K, ASN474K, ASN478K, ASN486K, ASN597L, ASN606L, ASN627L, ASN628L, ASN639L, ASN643L, ASN645L, ASP453K, ASP480K, ASP490K, ASP595L, ASP599L, ASP620L, ASP634L, ASP635L, ASP637L, GLN438K, GLN452K, GLN468K, GLN471K, GLN485K, GLN600L, GLN602L, GLN603L, GLN622L, GLN623L, GLU455K, GLU470K, GLU476K, GLU491K, GLU589L, GLU591L, GLU593L, GLU618L, GLU630L, GLU631L, GLY458K, GLY463K, GLY466K, GLY477K, GLY616L, GLY649L, HIS467K, HIS641L, ILE594L, ILE601L, ILE629L, ILE638L, LEU448K, LEU462K, LEU465K, LEU472K, LEU479K, LEU481K, LEU496K, LEU592L, LEU598L, LEU608L, LEU613L, LEU619L, LEU626L, LEU636L, LEU640L, LEU647L, LYS434K, LYS437K, LYS449K, LYS483K, LYS487K, LYS492K, LYS497K, LYS498K, LYS610L, LYS617L, LYS624L, MET450K, MET459K, MET464K, MET482K, MET590L, MET611L, MET642L, PHE435K, SER439K, SER440K, SER443K, SER469K, SER588L, SER605L, SER621L, SER632L, THR436K, THR444K, THR447K, THR461K, THR614L, THR615L, THR633L, THR644L, VAL441K, VAL475K, VAL484K, VAL488K, VAL493K, VAL604L