3B3F

the 2.2 a crystal structure of the catalytic domain of coactivator- associated arginine methyl transferase i(carm1,142-478), in complex with s-adenosyl homocysteine

• Total interactions analyzed: 6
• Total true interactions: 2
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 181
  • Norm. En. per Res.: -3.3208
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-110.4408	-2.5967	-488.029	-601.0665	181	15	21	18458	0	14	13
C-D	-93.6196	0.0	-490.037	-583.6566	177	15	21	18214	0	16	13

Interface residues

• A-B: ALA147A, ALA147B, ALA204A, ALA204B, ALA223A, ALA223B, ALA311A, ALA311B, ALA326A, ALA326B, ALA330A, ALA330B, ALA331A, ALA331B, ARG169A, ARG169B, ARG175A, ARG175B, ARG328A, ARG328B, ARG337A, ARG337B, ARG446A, ARG446B, ASN162A, ASN162B, ASN230A, ASN230B, ASN231A, ASN231B, ASN312A, ASN312B, ASN472A, ASN472B, ASP166A, ASP166B, ASP323A, ASP323B, ASP333A, ASP333B, ASP469A, ASP469B, GLN149A, GLN149B, GLN152A, GLN152B, GLN159A, GLN159B, GLN160A, GLN160B, GLN161A, GLN161B, GLN165A, GLN165B, GLN174A, GLN174B, GLN205A, GLN205B, GLN221A, GLN221B, GLN316A, GLN316B, GLN338A, GLN338B, GLU143B, GLU144A, GLU144B, GLU224A, GLU224B, GLU334A, GLU334B, GLY155A, GLY155B, GLY171A, GLY171B, GLY195A, GLY195B, GLY197A, GLY197B, GLY321A, GLY321B, GLY329A, GLY329B, HIS222A, HIS222B, HIS320A, HIS320B, ILE198A, ILE198B, ILE236A, ILE236B, LEU157A, LEU157B, LEU178A, LEU178B, LEU199A, LEU199B, LEU226A, LEU226B, LEU232A, LEU232B, LEU324A, LEU324B, LEU327A, LEU327B, LYS228A, LYS228B, LYS310A, LYS310B, LYS445A, LYS471A, LYS471B, MET163A, MET163B, MET164A, MET164B, MET219A, MET219B, PHE153A, PHE153B, PHE201A, PHE201B, PHE202A, PHE202B, PHE313A, PHE313B, PHE319A, PHE319B, PHE474A, PRO317A, PRO317B, PRO473A, SER145A, SER145B, SER146A, SER146B, SER158A, SER158B, SER196A, SER196B, SER200A, SER200B, SER229A, SER229B, SER318A, SER318B, SER325A, SER325B, THR142A, THR142B, THR170A, THR170B, THR172A, THR172B, THR309A, THR309B, TRP314A, TRP314B, TYR150A, TYR150B, TYR156A, TYR156B, TYR167A, TYR167B, TYR173A, TYR173B, TYR315B, TYR335A, TYR335B, VAL148A, VAL148B, VAL168A, VAL168B, VAL225A, VAL225B, VAL227A, VAL227B, VAL322A, VAL322B, VAL332A, VAL332B
• C-D: ALA204C, ALA204D, ALA223C, ALA223D, ALA311C, ALA311D, ALA326C, ALA326D, ALA330C, ALA330D, ALA331C, ALA331D, ARG169C, ARG169D, ARG175C, ARG175D, ARG328C, ARG328D, ARG337C, ARG337D, ARG446C, ARG446D, ASN162C, ASN162D, ASN230C, ASN230D, ASN231C, ASN231D, ASN312C, ASN312D, ASN472C, ASN472D, ASP166C, ASP166D, ASP323C, ASP323D, ASP333C, ASP333D, ASP469C, ASP469D, GLN149C, GLN149D, GLN152C, GLN152D, GLN159C, GLN159D, GLN160C, GLN160D, GLN161C, GLN161D, GLN165C, GLN165D, GLN174C, GLN174D, GLN205C, GLN205D, GLN221C, GLN221D, GLN316C, GLN316D, GLN338C, GLN338D, GLU143D, GLU144C, GLU144D, GLU224C, GLU224D, GLU334C, GLU334D, GLY155C, GLY155D, GLY171C, GLY171D, GLY195C, GLY195D, GLY197C, GLY197D, GLY321C, GLY321D, GLY329C, GLY329D, HIS222C, HIS222D, HIS320C, HIS320D, ILE198C, ILE198D, ILE236C, ILE236D, LEU157C, LEU157D, LEU178C, LEU178D, LEU199C, LEU199D, LEU226C, LEU226D, LEU232C, LEU232D, LEU324C, LEU324D, LEU327C, LEU327D, LYS228C, LYS228D, LYS310C, LYS310D, LYS471C, LYS471D, MET163C, MET163D, MET164C, MET164D, MET219C, MET219D, PHE153D, PHE201C, PHE201D, PHE202C, PHE202D, PHE313C, PHE313D, PHE319C, PHE319D, PHE474C, PRO317C, PRO317D, PRO473C, SER145C, SER145D, SER146C, SER146D, SER158C, SER158D, SER196C, SER196D, SER200C, SER200D, SER229C, SER229D, SER318C, SER318D, SER325C, SER325D, THR142C, THR142D, THR170C, THR170D, THR172C, THR172D, THR309C, THR309D, THR478C, THR478D, TRP314C, TRP314D, TYR156C, TYR156D, TYR167C, TYR167D, TYR173D, TYR315C, TYR315D, TYR335C, TYR335D, VAL148C, VAL148D, VAL168C, VAL168D, VAL225C, VAL225D, VAL227C, VAL227D, VAL322C, VAL322D, VAL332C, VAL332D