3B08

crystal structure of the mouse hoil1-l-nzf in complex with linear di- ubiquitin

• Total interactions analyzed: 28
• Total true interactions: 12
• Strongest Interaction:
  • Chains: B-G
  • Int. Res.: 71
  • Norm. En. per Res.: -3.5369
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-29.8422	-26.8507	-199.308	-256.0009	74	5	1	7964	3	25	25
A-G	-3.5899	1.773	-36.6018	-38.4187	27	3	0	1517	0	0	7
A-H	-32.1976	-47.987	-139.002	-219.1866	67	6	5	7493	2	19	12
B-G	-38.2514	-41.9004	-170.968	-251.1197	71	7	3	7927	5	21	13
B-H	0.0	8.1684	-33.6034	-25.435	27	4	1	1196	0	4	2
D-E	-18.2203	-28.8697	-195.631	-242.7209	76	3	1	7982	3	27	25
D-J	-13.6161	0.9656	-29.3235	-41.9741	23	1	0	1510	0	0	8
D-K	-28.4807	-43.124	-171.144	-242.7487	70	4	6	7658	4	21	12
E-J	-35.1624	-40.1308	-155.418	-230.7112	71	9	6	7797	2	20	12
E-K	0.0	29.4115	-32.9183	-3.5068	25	5	2	1067	0	4	2
G-H	-16.6527	-13.9855	-222.892	-253.5302	81	5	2	8555	3	26	27
J-K	-16.1795	-17.6916	-232.612	-266.4831	82	6	1	8998	2	26	30

Interface residues

• A-B: ALA122A, ALA217B, ALA244B, ALA46A, ARG208B, ARG216B, ARG218B, ARG237B, ARG42A, ARG72A, ASN204B, CYS197B, CYS200B, CYS211B, CYS214B, CYS215B, GLN196B, GLN49A, GLN78A, GLU140A, GLU212B, GLU233B, GLU234B, GLU241B, GLU92A, GLY123A, GLY199B, GLY210B, GLY47A, HIS144A, HIS68A, ILE203B, ILE44A, ILE79A, ILE89A, LEU143A, LEU245B, LEU43A, LEU50A, LEU67A, LEU69A, LEU71A, LEU8A, LEU91A, LYS105A, LYS109A, LYS139A, LYS205B, LYS48A, LYS6A, LYS82A, LYS87A, MET191B, MET213B, MET77A, PHE121A, PHE202B, PHE45A, PHE80A, PRO192B, PRO198B, PRO209B, SER141A, THR142A, THR201B, THR207B, THR66A, THR7A, THR88A, THR90A, TRP195B, VAL70A, VAL81A, VAL93A
• A-G: GLY86A, GLY86G, HIS144A, HIS144G, ILE89A, ILE89G, LEU143G, LEU145G, LEU84A, LEU84G, LYS82A, LYS82G, LYS87A, LYS87G, PHE80A, PHE80G, THR142A, THR142G, THR83A, THR83G, THR85A, THR85G, THR88A, THR88G, VAL146G, VAL81A, VAL81G
• A-H: ALA122A, ALA226H, ALA239H, ALA244H, ARG118A, ARG148A, ARG150A, ARG208H, ARG218H, ARG235H, ARG237H, ARG246H, ASP108A, ASP115A, GLN107A, GLN116A, GLN125A, GLN223H, GLN229H, GLN249H, GLU110A, GLU220H, GLU234H, GLU241H, GLU242H, GLU243H, GLY111A, GLY123A, GLY151A, GLY210H, GLY240H, GLY86A, HIS144A, ILE106A, ILE112A, ILE120A, ILE224H, ILE89A, LEU119A, LEU143A, LEU145A, LEU147A, LEU149A, LEU238H, LEU245H, LEU84A, LYS109A, LYS124A, LYS82A, LYS87A, PHE121A, PRO113A, PRO206H, PRO209H, PRO219H, PRO225H, PRO230H, SER227H, THR142A, THR207H, THR221H, THR83A, THR85A, THR88A, TYR222H, TYR228H, VAL146A
• B-G: ALA122G, ALA226B, ALA236B, ALA239B, ALA244B, ARG118G, ARG148G, ARG150G, ARG208B, ARG218B, ARG235B, ARG237B, ARG246B, ASP108G, ASP231B, GLN107G, GLN116G, GLN125G, GLN223B, GLN229B, GLN247B, GLU110G, GLU220B, GLU232B, GLU234B, GLU241B, GLU242B, GLU243B, GLY111G, GLY123G, GLY210B, GLY86G, HIS144G, ILE106G, ILE112G, ILE120G, ILE224B, ILE89G, LEU119G, LEU126G, LEU143G, LEU145G, LEU147G, LEU149G, LEU238B, LEU245B, LEU84G, LYS109G, LYS124G, LYS205B, LYS82G, LYS87G, PHE121G, PRO113G, PRO206B, PRO209B, PRO219B, PRO225B, PRO230B, SER227B, THR142G, THR207B, THR221B, THR83G, THR85G, THR88G, TRP195B, TYR222B, TYR228B, TYR248B, VAL146G
• B-H: ALA217B, ALA217H, ALA244B, ALA244H, ARG216B, ARG216H, ARG218B, ARG218H, ARG246B, ARG246H, GLN247B, GLN247H, GLN249H, GLU220B, GLU220H, GLU241B, GLU242B, GLU243B, LEU245B, LEU245H, PRO209H, PRO219B, PRO219H, THR221B, THR221H, TYR248B, TYR248H
• D-E: ALA122D, ALA217E, ALA244E, ALA46D, ARG208E, ARG216E, ARG218E, ARG237E, ARG42D, ARG72D, ASN204E, CYS197E, CYS200E, CYS211E, CYS214E, CYS215E, GLN196E, GLN49D, GLN78D, GLU140D, GLU212E, GLU220E, GLU233E, GLU234E, GLU241E, GLU242E, GLU92D, GLY123D, GLY199E, GLY210E, GLY47D, HIS144D, HIS68D, ILE203E, ILE44D, ILE79D, ILE89D, LEU143D, LEU238E, LEU245E, LEU43D, LEU50D, LEU67D, LEU69D, LEU71D, LEU8D, LEU91D, LYS109D, LYS139D, LYS205E, LYS48D, LYS6D, LYS82D, LYS87D, MET191E, MET213E, MET77D, PHE121D, PHE202E, PHE45D, PHE80D, PRO192E, PRO198E, PRO209E, SER141D, THR142D, THR201E, THR207E, THR66D, THR7D, THR88D, THR90D, TRP195E, VAL70D, VAL81D, VAL93D
• D-J: GLY86D, GLY86J, HIS144D, HIS144J, ILE89D, LEU84D, LEU84J, LYS82D, LYS82J, LYS87D, LYS87J, PHE80D, PHE80J, THR142D, THR142J, THR83D, THR83J, THR85D, THR85J, THR88D, THR88J, VAL146J, VAL81D
• D-K: ALA122D, ALA217K, ALA226K, ALA239K, ALA244K, ARG118D, ARG148D, ARG150D, ARG208K, ARG218K, ARG235K, ARG237K, ARG246K, ASP108D, ASP115D, GLN107D, GLN116D, GLN117D, GLN125D, GLN223K, GLN229K, GLN247K, GLU110D, GLU220K, GLU234K, GLU241K, GLU242K, GLU243K, GLY111D, GLY123D, GLY151D, GLY210K, GLY240K, GLY86D, HIS144D, ILE106D, ILE112D, ILE120D, ILE224K, ILE89D, LEU119D, LEU126D, LEU143D, LEU145D, LEU147D, LEU149D, LEU238K, LEU245K, LEU84D, LYS109D, LYS124D, LYS82D, LYS87D, PHE121D, PRO113D, PRO206K, PRO209K, PRO219K, PRO225K, PRO230K, SER227K, THR207K, THR221K, THR83D, THR85D, THR88D, TYR222K, TYR228K, TYR248K, VAL146D
• E-J: ALA122J, ALA226E, ALA239E, ALA244E, ARG118J, ARG148J, ARG208E, ARG218E, ARG235E, ARG237E, ARG246E, ASP108J, ASP115J, GLN107J, GLN116J, GLN117J, GLN125J, GLN223E, GLN229E, GLN247E, GLN249E, GLU110J, GLU220E, GLU234E, GLU241E, GLU242E, GLU243E, GLY111J, GLY123J, GLY210E, GLY240E, GLY86J, HIS144J, ILE106J, ILE112J, ILE120J, ILE224E, ILE89J, LEU119J, LEU126J, LEU143J, LEU145J, LEU147J, LEU149J, LEU238E, LEU245E, LEU84J, LYS109J, LYS124J, LYS205E, LYS82J, LYS87J, PHE121J, PRO113J, PRO206E, PRO209E, PRO219E, PRO225E, PRO230E, SER227E, THR142J, THR207E, THR221E, THR83J, THR85J, THR88J, TRP195E, TYR222E, TYR228E, TYR248E, VAL146J
• E-K: ALA217E, ALA217K, ALA244E, ALA244K, ARG216E, ARG216K, ARG218E, ARG218K, ARG246E, GLN247E, GLN247K, GLU220E, GLU220K, GLU241E, GLU242E, GLU243E, LEU245E, LEU245K, PRO209E, PRO219E, PRO219K, THR221E, THR221K, TYR248E, TYR248K
• G-H: ALA122G, ALA217H, ALA244H, ALA46G, ARG208H, ARG216H, ARG218H, ARG237H, ARG42G, ARG72G, ASN204H, CYS197H, CYS200H, CYS211H, CYS214H, CYS215H, GLN196H, GLN247H, GLN249H, GLN49G, GLN78G, GLU140G, GLU212H, GLU220H, GLU233H, GLU234H, GLU241H, GLU92G, GLY123G, GLY199H, GLY210H, GLY240H, GLY47G, HIS144G, HIS68G, ILE120G, ILE203H, ILE44G, ILE79G, ILE89G, LEU143G, LEU245H, LEU43G, LEU50G, LEU67G, LEU69G, LEU71G, LEU8G, LEU91G, LYS105G, LYS109G, LYS124G, LYS139G, LYS205H, LYS48G, LYS6G, LYS82G, LYS87G, MET191H, MET213H, MET77G, PHE121G, PHE202H, PHE45G, PHE80G, PRO192H, PRO198H, PRO209H, SER141G, THR142G, THR201H, THR207H, THR66G, THR7G, THR88G, THR90G, TRP195H, TYR248H, VAL70G, VAL81G, VAL93G
• J-K: ALA122J, ALA217K, ALA244K, ALA46J, ARG208K, ARG216K, ARG218K, ARG237K, ARG42J, ARG72J, ASN204K, CYS197K, CYS200K, CYS211K, CYS214K, CYS215K, GLN196K, GLN247K, GLN49J, GLN78J, GLU140J, GLU212K, GLU220K, GLU233K, GLU234K, GLU241K, GLU92J, GLY123J, GLY199K, GLY210K, GLY47J, GLY86J, HIS144J, HIS190K, HIS68J, ILE120J, ILE203K, ILE44J, ILE79J, ILE89J, LEU143J, LEU245K, LEU43J, LEU50J, LEU67J, LEU69J, LEU71J, LEU8J, LEU91J, LYS105J, LYS109J, LYS124J, LYS139J, LYS205K, LYS48J, LYS6J, LYS82J, LYS87J, MET191K, MET213K, MET77J, PHE121J, PHE202K, PHE45J, PHE80J, PRO192K, PRO198K, PRO209K, SER141J, THR142J, THR201K, THR207K, THR66J, THR7J, THR88J, THR90J, TRP195K, TYR248K, TYR59J, VAL70J, VAL81J, VAL93J