3ASV

the closed form of serine dehydrogenase complexed with nadp+

• Total interactions analyzed: 15
• Total true interactions: 10
• Strongest Interaction:
  • Chains: C-E
  • Int. Res.: 75
  • Norm. En. per Res.: -6.084
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-128.7881	-103.4079	-635.05	-867.246	172	30	19	23414	8	43	50
A-C	0.0	9.0853	-6.2201	2.8652	25	1	1	536	0	6	8
A-D	-5.5848	5.5108	-24.5204	-24.5944	31	3	0	1434	0	20	18
B-D	0.0	29.3339	-34.8189	-5.485	37	5	0	1658	0	37	36
C-D	-104.9994	-104.0312	-641.834	-850.8646	175	27	19	23600	10	42	48
C-E	-148.6917	0.0	-307.609	-456.3007	75	22	11	11591	0	2	2
C-F	-158.3476	-44.4691	-442.098	-644.9147	131	35	8	17316	4	18	9
D-E	-123.224	-36.7433	-429.889	-589.8563	135	32	10	17115	4	18	9
D-F	-133.6207	0.0	-332.12	-465.7407	78	18	11	11731	0	2	2
E-F	-127.6621	-90.2644	-642.669	-860.5955	173	21	18	23576	7	42	51

Interface residues

• A-B: ALA116A, ALA116B, ALA136A, ALA136B, ALA142A, ALA142B, ALA149A, ALA149B, ALA152A, ALA152B, ALA91A, ALA91B, ALA94A, ALA94B, ARG115A, ARG115B, ARG155A, ARG155B, ARG162A, ARG162B, ARG189A, ARG247A, ARG247B, ARG56A, ARG56B, ARG58A, ARG58B, ASN106A, ASN106B, ASN107A, ASN107B, ASN125A, ASN125B, ASN145A, ASN145B, ASN160A, ASN160B, ASN229A, ASN229B, ASN244A, ASN244B, ASP104A, ASP104B, ASP164A, ASP164B, ASP98A, ASP98B, GLN156A, GLN156B, GLN248A, GLN248B, GLU100A, GLU100B, GLU123A, GLU123B, GLU62A, GLU62B, GLU89A, GLU89B, GLU97A, GLU97B, GLY109A, GLY109B, GLY120A, GLY120B, GLY137A, GLY137B, GLY143A, GLY143B, GLY144A, GLY144B, GLY148A, GLY148B, GLY167A, GLY167B, GLY242A, HIS166A, HIS166B, HIS246A, HIS246B, HIS92A, HIS92B, ILE103A, ILE103B, ILE129A, ILE129B, ILE61A, ILE61B, LEU110A, LEU110B, LEU118A, LEU118B, LEU159A, LEU159B, LEU161A, LEU161B, LEU165A, LEU165B, LEU243A, LEU243B, LYS108A, LYS108B, LYS151A, LYS151B, LYS93A, LYS93B, MET102A, MET102B, MET113A, MET113B, MET121A, MET121B, MET88A, MET88B, PHE153A, PHE153B, PHE157A, PHE157B, PRO119A, PRO119B, PRO140A, PRO140B, PRO90A, PRO90B, SER134B, SER138A, SER138B, SER158A, SER158B, SER95A, SER95B, THR101A, THR101B, THR105A, THR105B, THR114A, THR114B, THR135A, THR135B, THR150A, THR150B, THR163A, THR163B, THR168A, THR168B, TRP139A, TRP139B, TRP99A, TRP99B, TYR112A, TYR112B, TYR141A, TYR141B, TYR147A, TYR147B, VAL111A, VAL111B, VAL117A, VAL117B, VAL122A, VAL122B, VAL146A, VAL146B, VAL154A, VAL154B, VAL170A, VAL170B, VAL172B, VAL245A, VAL245B, VAL96A, VAL96B
• A-C: ALA59C, ALA66A, ALA66C, ALA70A, ARG115C, ARG124A, ARG58C, ASN74A, CYS73A, CYS73C, GLU123A, GLU123C, GLU62A, GLU62C, GLU63A, GLY120C, LEU65A, LEU65C, LEU68A, PRO119A, PRO119C, PRO69A, SER67A, TYR49A, VAL122C
• A-D: ALA59A, ALA60A, ALA66A, ALA91D, ALA94D, ARG115A, ARG58A, ASN187D, ASN57A, ASP193D, ASP194D, ASP98D, GLU62A, GLU63A, GLU89D, GLU97D, GLY192D, GLY87D, HIS92D, LEU65A, LEU68A, LYS191D, LYS196D, LYS93D, MET64A, PHE190D, PRO119A, PRO90D, SER67A, SER95D, TYR112A
• B-D: ALA197B, ARG32D, ARG33B, ARG33D, ARG36B, ARG36D, ARG56B, ASN187B, ASN187D, ASP193B, ASP193D, ASP194B, ASP194D, ASP98B, GLN34D, GLN38D, GLN52D, GLU100B, GLU184B, GLU35D, GLU97B, GLY192B, GLY192D, GLY195B, LEU37D, LEU86D, LYS191B, LYS191D, LYS196B, PHE190B, PHE190D, SER186B, SER95B, THR101B, VAL188B, VAL188D, VAL96B
• C-D: ALA116C, ALA116D, ALA136C, ALA136D, ALA142C, ALA142D, ALA149C, ALA149D, ALA152C, ALA152D, ALA169C, ALA169D, ALA91C, ALA91D, ALA94C, ALA94D, ARG115C, ARG115D, ARG155C, ARG155D, ARG162C, ARG162D, ARG189C, ARG189D, ARG247C, ARG247D, ARG56C, ARG56D, ARG58C, ARG58D, ASN106C, ASN106D, ASN107C, ASN107D, ASN125C, ASN125D, ASN145C, ASN145D, ASN160C, ASN160D, ASN229C, ASN229D, ASN244C, ASN244D, ASP104C, ASP104D, ASP164C, ASP164D, ASP98C, ASP98D, GLN156C, GLN156D, GLN248C, GLN248D, GLU100C, GLU100D, GLU123C, GLU123D, GLU62C, GLU62D, GLU89C, GLU89D, GLU97C, GLU97D, GLY109C, GLY109D, GLY120C, GLY120D, GLY137C, GLY137D, GLY143C, GLY143D, GLY144C, GLY144D, GLY148C, GLY148D, GLY167C, GLY167D, GLY242C, GLY242D, HIS166C, HIS166D, HIS246C, HIS246D, HIS92C, HIS92D, ILE103C, ILE103D, ILE129C, ILE129D, ILE61C, ILE61D, LEU110C, LEU110D, LEU118C, LEU118D, LEU159C, LEU159D, LEU161C, LEU161D, LEU165C, LEU165D, LEU243C, LEU243D, LYS108C, LYS108D, LYS151C, LYS151D, LYS93C, LYS93D, MET102C, MET102D, MET113C, MET113D, MET121C, MET121D, MET88C, MET88D, PHE153C, PHE153D, PHE157C, PHE157D, PRO119C, PRO119D, PRO140C, PRO140D, PRO90C, PRO90D, SER134C, SER134D, SER138C, SER138D, SER158C, SER158D, SER95C, SER95D, THR101C, THR101D, THR105C, THR114C, THR114D, THR135C, THR135D, THR150C, THR150D, THR163C, THR163D, THR168C, THR168D, TRP139C, TRP139D, TRP99C, TRP99D, TYR112C, TYR112D, TYR141C, TYR141D, TYR147C, TYR147D, VAL111C, VAL111D, VAL117C, VAL117D, VAL122C, VAL122D, VAL146C, VAL146D, VAL154C, VAL154D, VAL170C, VAL170D, VAL245C, VAL245D, VAL96C, VAL96D
• C-E: ALA136C, ALA136E, ALA142C, ALA142E, ALA206C, ALA206E, ALA241C, ALA241E, ARG155C, ARG247C, ARG247E, ASN203C, ASN203E, ASN244C, ASN244E, GLN202C, GLN202E, GLN238C, GLN238E, GLN248C, GLN248E, GLU198C, GLU198E, GLU232C, GLU232E, GLY137C, GLY137E, GLY178C, GLY178E, GLY242C, GLY242E, HIS246C, HIS246E, LEU179C, LEU179E, LEU243C, LEU243E, LYS199C, LYS199E, MET234C, MET234E, PRO140C, PRO140E, PRO177C, PRO177E, PRO235C, PRO235E, SER134C, SER134E, SER138C, SER138E, SER239C, SER239E, THR135C, THR135E, THR200C, THR200E, THR204C, THR204E, THR237C, THR237E, TRP139C, TRP139E, TYR141C, TYR141E, TYR201C, TYR201E, TYR240C, TYR240E, VAL205C, VAL205E, VAL236C, VAL236E, VAL245C, VAL245E
• C-F: ALA169C, ALA169F, ALA206C, ALA206F, ALA215C, ALA215F, ALA224C, ALA224F, ALA241C, ALA241F, ARG155C, ARG155F, ARG162C, ARG162F, ARG171C, ARG171F, ASN160C, ASN160F, ASN227C, ASN227F, ASN229C, ASN229F, ASP164C, ASP164F, ASP174C, ASP174F, ASP211C, ASP211F, GLN156C, GLN156F, GLN238C, GLN238F, GLU176C, GLU176F, GLU210C, GLU210F, GLU214C, GLU214F, GLU232C, GLU232F, GLY127C, GLY127F, GLY167C, GLY167F, GLY178C, GLY178F, GLY242C, GLY242F, HIS166C, HIS166F, HIS225C, HIS225F, ILE175C, ILE175F, ILE228C, ILE228F, LEU159C, LEU159F, LEU161C, LEU161F, LEU165C, LEU165F, LEU179C, LEU179F, LEU207C, LEU207F, LEU222C, LEU222F, LEU231C, LEU231F, MET233C, MET233F, MET234C, MET234F, PRO177C, PRO177F, PRO209C, PRO209F, PRO223C, PRO223F, PRO235C, PRO235F, SER138C, SER138F, SER158C, SER158F, SER213C, SER213F, SER239C, SER239F, THR135C, THR135F, THR163C, THR163F, THR168C, THR168F, THR173C, THR173F, THR204F, THR208C, THR208F, THR230C, THR230F, THR237C, THR237F, TRP139C, TRP139F, TRP217C, TRP217F, TRP218C, TRP218F, TYR240C, TYR240F, VAL170C, VAL170F, VAL172C, VAL172F, VAL180C, VAL180F, VAL205C, VAL205F, VAL212C, VAL212F, VAL216C, VAL216F, VAL219C, VAL219F, VAL226C, VAL226F, VAL236C, VAL236F
• D-E: ALA169D, ALA169E, ALA206D, ALA206E, ALA215D, ALA215E, ALA224D, ALA224E, ALA241D, ALA241E, ARG155D, ARG155E, ARG162D, ARG162E, ARG171D, ARG171E, ARG19D, ARG19E, ASN160D, ASN160E, ASN227D, ASN227E, ASN229D, ASN229E, ASP164D, ASP164E, ASP174D, ASP174E, ASP211D, ASP211E, GLN156D, GLN156E, GLN238D, GLN238E, GLU176D, GLU176E, GLU210D, GLU210E, GLU214D, GLU214E, GLU232D, GLU232E, GLY127D, GLY127E, GLY167D, GLY167E, GLY178D, GLY178E, GLY181E, GLY242D, GLY242E, HIS166D, HIS166E, HIS225D, HIS225E, ILE175D, ILE175E, ILE228D, ILE228E, LEU159D, LEU159E, LEU161D, LEU161E, LEU165D, LEU165E, LEU179D, LEU179E, LEU207D, LEU207E, LEU222D, LEU222E, LEU231D, LEU231E, MET233D, MET233E, MET234D, MET234E, PRO177D, PRO177E, PRO209D, PRO209E, PRO223D, PRO223E, PRO235D, PRO235E, SER138D, SER138E, SER158D, SER158E, SER213D, SER213E, SER239D, SER239E, THR135D, THR135E, THR163D, THR163E, THR168D, THR168E, THR173D, THR173E, THR208D, THR208E, THR221D, THR221E, THR230D, THR230E, THR237D, THR237E, TRP139D, TRP139E, TRP217D, TRP217E, TRP218D, TRP218E, TYR240D, TYR240E, VAL170D, VAL170E, VAL172D, VAL172E, VAL180D, VAL180E, VAL205D, VAL205E, VAL212D, VAL212E, VAL216D, VAL216E, VAL219D, VAL219E, VAL226D, VAL226E, VAL236D, VAL236E
• D-F: ALA136D, ALA136F, ALA142D, ALA142F, ALA197F, ALA206D, ALA206F, ALA241D, ALA241F, ARG155D, ARG155F, ARG247D, ARG247F, ASN203D, ASN203F, ASN244D, ASN244F, GLN202D, GLN202F, GLN238D, GLN238F, GLN248D, GLN248F, GLU198D, GLU198F, GLU232D, GLU232F, GLY137D, GLY137F, GLY178D, GLY178F, GLY242D, GLY242F, HIS246D, HIS246F, LEU179D, LEU179F, LEU243D, LEU243F, LYS199D, LYS199F, MET233D, MET233F, MET234D, MET234F, PRO140D, PRO140F, PRO177D, PRO177F, PRO235D, PRO235F, SER134D, SER138D, SER138F, SER239D, SER239F, THR135D, THR135F, THR200D, THR200F, THR204D, THR204F, THR237D, THR237F, TRP139D, TRP139F, TYR141D, TYR141F, TYR201D, TYR201F, TYR240D, TYR240F, VAL205D, VAL205F, VAL236D, VAL236F, VAL245D, VAL245F
• E-F: ALA116E, ALA116F, ALA136E, ALA136F, ALA142E, ALA142F, ALA149E, ALA149F, ALA152E, ALA152F, ALA169E, ALA169F, ALA91E, ALA91F, ALA94E, ALA94F, ARG115E, ARG115F, ARG155E, ARG155F, ARG162E, ARG162F, ARG189E, ARG189F, ARG247E, ARG247F, ARG56E, ARG56F, ARG58E, ARG58F, ASN106E, ASN106F, ASN107E, ASN107F, ASN125E, ASN145E, ASN145F, ASN160E, ASN160F, ASN229E, ASN229F, ASN244E, ASN244F, ASP104E, ASP104F, ASP164E, ASP164F, ASP98E, ASP98F, GLN156E, GLN156F, GLN248E, GLN248F, GLU100E, GLU100F, GLU123E, GLU123F, GLU62E, GLU89E, GLU89F, GLU97E, GLU97F, GLY109E, GLY109F, GLY120E, GLY120F, GLY137E, GLY137F, GLY143E, GLY143F, GLY144E, GLY144F, GLY148E, GLY148F, GLY167E, GLY167F, GLY242E, HIS166E, HIS166F, HIS246E, HIS246F, HIS92E, HIS92F, ILE103E, ILE103F, ILE129E, ILE129F, ILE61E, ILE61F, LEU110E, LEU110F, LEU118E, LEU118F, LEU159E, LEU159F, LEU161E, LEU161F, LEU165E, LEU165F, LEU243E, LEU243F, LYS108E, LYS108F, LYS151E, LYS151F, LYS93E, LYS93F, MET102E, MET102F, MET113E, MET113F, MET121E, MET121F, MET88E, MET88F, PHE153E, PHE153F, PHE157E, PHE157F, PRO119E, PRO119F, PRO140E, PRO140F, PRO90E, PRO90F, SER134E, SER138E, SER138F, SER158E, SER158F, SER95E, SER95F, THR101E, THR101F, THR105E, THR105F, THR114E, THR114F, THR135E, THR135F, THR150E, THR150F, THR163E, THR163F, THR168E, THR168F, TRP139E, TRP139F, TRP99E, TRP99F, TYR112E, TYR112F, TYR141E, TYR141F, TYR147E, TYR147F, VAL111E, VAL111F, VAL117E, VAL117F, VAL122E, VAL122F, VAL146E, VAL146F, VAL154E, VAL154F, VAL170E, VAL170F, VAL172F, VAL245E, VAL245F, VAL96E, VAL96F