3ARC

crystal structure of oxygen-evolving photosystem ii at 1.9 angstrom resolution

• Total interactions analyzed: 703
• Total true interactions: 153
• Strongest Interaction:
  • Chains: C-T
  • Int. Res.: 16
  • Norm. En. per Res.: -6.039
• Hub Node: A(27)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-35.3014	-43.6181	-221.082	-300.0015	85	9	6	8122	0	14	10
A-C	-90.2245	-39.6452	-885.6	-1015.4697	286	19	20	33484	6	30	32
A-D	-243.0736	-11.3544	-1725.09	-1979.518	420	54	48	65247	9	54	59
A-E	-21.5068	4.7095	-59.9695	-76.7668	35	3	1	2690	0	5	6
A-F	-2.8409	-8.2722	-30.8753	-41.9884	14	1	0	909	0	1	3
A-I	-19.9612	12.4632	-251.851	-259.349	82	5	6	9044	4	6	10
A-J	-9.6908	0.0	-28.8602	-38.551	23	1	1	1297	0	0	0
A-L	-5.2009	5.0087	-50.1742	-50.3664	39	4	1	1926	0	1	2
A-M	0.0	0.0	-4.7042	-4.7042	11	0	0	184	0	0	0
A-O	-38.5232	-49.962	-200.774	-289.2592	83	11	2	7874	1	23	17
A-T	0.0	0.0	-109.46	-109.46	52	1	4	4560	0	2	2
A-U	0.0	0.0	-26.3663	-26.3663	11	0	0	702	0	2	1
A-V	-41.251	-10.7692	-123.977	-175.9971	58	2	3	5424	1	14	15
A-b	0.0	0.0	-2.9619	-2.9619	20	0	1	371	0	0	2
B-D	-171.4842	-90.5217	-853.868	-1115.8739	276	33	28	32970	18	51	50
B-E	0.0	0.0	-18.9681	-18.9681	10	1	0	601	0	1	0
B-H	-143.2405	-53.4486	-565.639	-762.3281	157	21	10	20691	2	21	21
B-L	-34.5605	16.4943	-144.592	-162.6582	57	8	3	5415	0	5	6
B-M	0.0	3.5827	-11.7407	-8.158	26	0	0	804	0	2	2
B-O	-65.8485	-73.7719	-193.295	-332.9153	79	6	2	7006	3	18	25
B-U	-12.0773	-21.1042	-95.7895	-128.971	50	5	1	4173	3	23	20
B-V	0.0	0.0	-0.0502	-0.0502	7	0	0	32	0	2	3
B-X	-2.1312	-18.9345	-47.8787	-68.9444	18	1	0	1779	1	3	3
B-a	0.0	0.0	-2.8367	-2.8367	19	0	1	357	0	0	3
B-o	-8.686	-19.6329	-81.5244	-109.8432	57	3	0	3616	0	19	19
B-t	0.0	0.0	-19.8201	-19.8201	23	0	0	897	0	0	0
C-D	-89.3502	-86.553	-255.422	-431.3252	89	16	5	8631	4	13	16
C-I	-24.2391	-48.589	-129.186	-202.0141	53	7	3	5353	2	19	15
C-J	0.0	0.0	-8.5974	-8.5974	16	1	0	417	0	0	0
C-K	-51.2671	-15.3715	-228.679	-295.3176	87	6	12	8904	1	7	6
C-L	0.0	0.0	-0.0021	-0.0021	2	0	0	1	0	1	0
C-O	-76.4843	-73.2606	-405.586	-555.3309	110	19	3	14387	4	19	22
C-T	-22.0249	-40.1877	-34.4119	-96.6245	16	1	0	1069	2	2	1
C-U	-31.1822	-10.8535	-111.905	-153.9407	48	6	3	4539	1	7	11
C-V	-28.7705	-35.1543	-215.626	-279.5508	99	8	4	9217	4	30	21
C-Y	-7.2839	0.0	-14.316	-21.5999	19	0	0	574	0	0	0
C-Z	-2.4344	2.1237	-107.262	-107.5727	60	2	5	4186	0	2	1
C-l	0.0	0.0	-0.0571	-0.0571	2	0	0	16	0	0	1
D-E	-57.3601	-37.7995	-400.52	-495.6796	114	9	12	15241	3	12	14
D-F	-14.6844	0.0	-112.936	-127.6204	58	1	5	4576	0	2	2
D-H	-14.7748	0.0	-58.0134	-72.7882	39	1	0	2411	0	1	1
D-I	0.0	0.0	-0.0014	-0.0014	2	0	0	1	0	0	0
D-J	0.0	0.0	-16.3815	-16.3815	20	0	0	595	0	0	0
D-K	0.0	0.0	-0.6245	-0.6245	4	0	0	52	0	0	1
D-L	-17.7016	0.0	-99.0816	-116.7832	50	4	0	3325	0	0	0
D-M	0.0	8.6014	-37.7984	-29.197	17	1	0	1437	0	1	4
D-O	-28.5778	14.4474	-153.414	-167.5443	74	3	5	6607	3	34	32
D-T	0.0	0.0	-34.3688	-34.3688	32	0	3	1656	0	1	3
D-U	-17.1965	-3.1648	-24.2285	-44.5897	16	1	1	849	0	3	2
D-V	-14.8137	12.0267	-41.6045	-44.3915	21	2	1	1513	0	3	4
D-X	-18.1011	-52.1076	-138.615	-208.8237	63	1	2	6417	7	14	11
E-F	0.0	-8.2301	-236.929	-245.1591	72	0	11	8189	0	4	4
E-H	0.0	0.0	-21.269	-21.269	11	2	0	672	0	1	0
E-J	-21.4183	5.6261	-102.298	-118.0902	41	9	2	4354	0	3	4
E-V	-23.289	6.543	-53.9686	-70.7145	31	2	3	1815	0	7	7
E-X	0.0	0.0	-0.012	-0.012	2	0	0	8	0	0	1
F-J	-20.2683	0.0	-91.4956	-111.7639	33	5	5	3636	0	0	0
F-V	0.0	0.0	-3.5641	-3.5641	12	0	0	341	0	2	1
F-Y	0.0	0.0	-0.0061	-0.0061	3	0	0	5	0	0	0
F-X	0.0	0.0	-0.0614	-0.0614	6	0	0	35	0	1	0
H-L	0.0	-5.227	-3.0031	-8.2301	4	0	0	116	0	2	0
H-X	-28.7303	0.0	-72.4221	-101.1524	34	3	4	3082	0	2	0
J-K	0.0	0.0	-31.4406	-31.4406	24	0	1	1207	0	0	0
J-V	-7.8823	0.0	-6.4482	-14.3305	7	0	0	387	0	0	0
J-Y	0.0	0.0	-25.9417	-25.9417	31	0	0	1278	0	0	0
K-Y	-14.2448	0.0	-101.497	-115.7418	51	3	8	4916	0	0	0
K-Z	0.0	0.0	-58.1045	-58.1045	36	4	3	2522	0	0	0
L-M	-44.5173	-10.6637	-226.583	-281.764	62	6	14	8791	0	2	2
L-T	-3.2949	0.0	-164.253	-167.5479	52	7	11	6348	0	1	3
L-c	0.0	0.0	-0.0605	-0.0605	2	0	0	13	0	0	1
L-l	0.0	0.0	-0.0031	-0.0031	4	0	0	4	0	0	0
L-m	0.0	0.0	-0.1664	-0.1664	9	0	0	72	0	1	2
L-t	0.0	0.0	-0.0542	-0.0542	3	0	0	14	0	0	0
M-T	0.0	0.0	-25.5949	-25.5949	29	1	1	1504	0	2	3
M-l	0.0	0.0	-0.2447	-0.2447	9	0	0	86	0	1	2
M-m	-6.4143	0.0	-161.709	-168.1233	58	12	14	7087	0	0	2
M-t	0.0	0.0	-1.8747	-1.8747	5	0	0	122	0	0	0
O-U	-3.0535	5.9902	-113.469	-110.5323	62	2	12	5117	0	21	12
O-b	-15.1009	-24.1198	-93.6481	-132.8688	58	4	0	3918	0	19	19
T-b	0.0	0.0	-20.294	-20.294	23	0	0	907	0	0	0
T-l	0.0	0.0	-0.0548	-0.0548	3	0	0	14	0	0	0
T-m	0.0	0.0	-2.1522	-2.1522	6	0	0	174	0	0	0
U-V	-34.8151	-14.8966	-152.115	-201.8267	69	4	4	6342	1	13	9
Y-Z	-21.3443	-7.9683	-98.8869	-128.1995	41	2	8	4320	0	2	1
a-b	-33.2568	-30.6192	-198.428	-262.304	82	10	6	7875	0	14	11
a-c	-114.2484	-35.3953	-891.852	-1041.4957	286	20	20	33551	6	30	32
a-d	-262.1836	-21.1455	-1710.82	-1994.1491	421	50	47	64747	8	55	58
a-e	-26.596	4.6891	-63.1976	-85.1044	36	3	1	2715	0	5	6
a-f	-3.3226	-8.2235	-31.2085	-42.7546	14	1	0	919	0	1	3
a-i	-28.7399	12.5313	-269.065	-285.2736	86	6	6	9641	4	6	10
a-j	-9.3523	0.0	-29.0556	-38.4079	23	1	1	1302	0	0	0
a-l	-7.0811	4.8852	-50.4156	-52.6116	39	1	1	1946	0	1	2
a-m	0.0	0.0	-4.0799	-4.0799	11	0	0	178	0	0	0
a-o	-47.7754	-51.7124	-201.855	-301.3428	84	12	2	7905	1	24	17
a-t	0.0	0.0	-107.299	-107.299	53	4	4	4510	0	2	2
a-u	-14.6645	0.0	-26.4584	-41.1229	11	1	0	708	0	2	1
a-v	-40.547	-9.7677	-124.888	-175.2028	58	3	3	5408	1	14	15
b-d	-137.3322	-20.9438	-835.189	-993.465	271	33	26	32386	14	48	49
b-e	0.0	0.0	-16.346	-16.346	10	0	0	562	0	1	0
b-h	-127.5875	-45.8566	-550.504	-723.9481	159	24	11	20442	2	20	21
b-l	-37.6098	18.199	-144.765	-164.1758	57	7	3	5448	0	5	6
b-m	0.0	1.1844	-11.9809	-10.7965	28	0	0	810	0	2	2
b-o	-58.691	-71.2592	-191.833	-321.7831	79	9	2	7005	2	18	24
b-u	-12.5785	-22.0578	-97.3743	-132.0106	50	6	1	4184	3	21	20
b-v	0.0	0.0	-0.043	-0.043	8	0	0	29	0	1	3
b-x	-5.5226	-19.2626	-32.3808	-57.166	16	0	0	1393	1	3	3
c-d	-88.0643	-47.842	-248.731	-384.6373	91	13	6	8495	2	13	17
c-i	-27.6084	-69.9648	-125.609	-223.1822	49	3	4	5239	3	19	15
c-j	0.0	0.0	-8.8832	-8.8832	16	0	0	401	0	0	0
c-k	-37.6973	-13.0795	-236.72	-287.4968	91	6	13	9604	1	7	7
c-l	0.0	0.0	-0.002	-0.002	2	0	0	1	0	1	0
c-o	-85.5773	-69.6792	-410.59	-565.8465	110	21	3	14666	4	19	22
c-t	-16.7974	-26.2384	-33.7048	-76.7406	16	1	0	1080	2	2	1
c-u	-28.723	-10.3529	-111.474	-150.55	45	4	4	4516	1	7	10
c-v	-25.688	-32.1692	-217.789	-275.6462	98	5	4	8981	5	29	21
c-y	-2.8213	0.0	-13.2031	-16.0244	20	0	0	560	0	0	1
c-z	-2.1336	2.2239	-107.456	-107.3657	59	2	6	4220	0	2	2
d-e	-39.3469	-36.7456	-396.151	-472.2435	113	10	12	15235	3	12	14
d-f	-9.1248	0.0	-115.622	-124.7468	58	2	5	4690	0	2	2
d-h	-13.1148	0.0	-53.8782	-66.993	37	1	0	2345	0	1	1
d-j	0.0	0.0	-17.0926	-17.0926	20	0	0	605	0	0	0
d-k	0.0	0.0	-0.1876	-0.1876	3	0	0	25	0	0	1
d-l	-15.0845	0.0	-99.3862	-114.4707	51	4	0	3343	0	0	0
d-m	0.0	6.0771	-37.479	-31.4019	17	0	0	1449	0	1	4
d-o	-21.2678	11.843	-153.26	-162.6848	72	2	5	6624	3	34	33
d-t	0.0	0.0	-35.3116	-35.3116	33	0	3	1685	0	1	3
d-u	-18.2586	-3.1587	-23.9348	-45.352	16	1	1	865	0	3	2
d-v	-12.8954	12.8218	-40.5798	-40.6534	22	4	1	1548	0	3	4
d-x	-30.8375	-77.8413	-138.225	-246.9038	63	3	2	6327	7	13	11
e-f	0.0	-8.0383	-197.498	-205.5363	66	1	11	6847	0	4	3
e-h	0.0	0.0	-21.8039	-21.8039	10	3	0	665	0	1	0
e-j	-27.5814	2.8457	-129.228	-153.9637	44	9	1	5298	0	3	4
e-v	-22.7811	7.8915	-51.0226	-65.9122	32	1	3	1867	0	7	8
e-x	0.0	0.0	-0.0175	-0.0175	2	0	0	10	0	0	1
f-j	-19.6926	0.0	-87.0268	-106.7194	33	2	5	3545	0	0	0
f-v	0.0	0.0	-3.1041	-3.1041	12	0	0	333	0	2	1
f-y	0.0	0.0	-0.0007	-0.0007	2	0	0	2	0	0	0
f-x	0.0	0.0	-0.0348	-0.0348	8	0	0	32	0	1	0
h-l	0.0	-5.5878	-1.2452	-6.833	4	0	0	97	0	2	0
h-x	-15.873	0.0	-70.4124	-86.2854	35	1	4	3008	0	2	0
i-o	0.0	0.0	-0.0004	-0.0004	2	0	0	1	0	0	0
j-k	0.0	0.0	-30.8032	-30.8032	24	0	1	1210	0	0	0
j-v	-10.0872	0.0	-8.4593	-18.5465	8	1	0	379	0	0	0
j-y	0.0	0.0	-27.0256	-27.0256	30	0	0	1251	0	0	0
k-v	0.0	0.0	-0.0003	-0.0003	2	0	0	1	0	0	0
k-y	-9.8623	0.0	-95.2898	-105.1521	50	4	8	4826	0	0	0
k-z	0.0	0.0	-61.4363	-61.4363	39	3	3	2744	0	0	0
l-m	-40.0298	-10.8041	-224.938	-275.7718	61	4	14	8717	0	2	2
l-t	-10.3423	-10.1175	-169.992	-190.4518	52	2	12	6222	0	1	3
m-t	0.0	0.0	-24.3582	-24.3582	30	1	1	1508	0	2	3
o-u	-4.5673	0.641	-113.718	-117.6442	64	1	12	5186	0	21	12
u-v	-39.6932	-14.756	-152.854	-207.3032	69	5	4	6431	1	13	9
y-z	-24.2141	-8.6687	-98.8711	-131.7538	41	3	8	4398	0	2	1

Interface residues

• A-B: ALA233A, ALA250A, ALA251A, ALA263A, ARG225A, ARG257A, ARG334A, ARG384B, ARG472B, ARG476B, ARG7B, ASN14B, ASN234A, ASN247A, ASN266A, ASP477B, ASP483B, GLN261A, GLN490B, GLU226A, GLU229A, GLU231A, GLU485B, GLU489B, GLU492B, GLY236A, GLY253A, GLY256A, GLY2B, GLY481B, GLY494B, GLY500B, HIS252A, HIS337A, ILE13B, ILE224A, ILE248A, ILE259A, ILE482B, LEU218A, LEU223A, LEU258A, LEU3B, LEU486B, LYS498B, MET331A, PHE255A, PHE260A, PHE265A, PHE383B, PHE475B, PHE479B, PHE495B, PRO340A, PRO484B, PRO488B, PRO4B, SER221A, SER222A, SER232A, SER264A, SER480B, SER487B, THR10B, THR220A, THR227A, THR228A, THR230A, THR245A, TRP468B, TRP493B, TRP5B, TYR235A, TYR246A, TYR254A, TYR262A, TYR496B, TYR6B, VAL11B, VAL219A, VAL249A, VAL330A, VAL478B, VAL491B, VAL499B
• A-C: ALA146A, ALA149A, ALA152A, ALA156A, ALA188A, ALA276A, ALA277A, ALA287A, ALA294A, ALA309C, ALA312C, ALA314C, ALA318A, ALA324A, ALA331C, ALA336A, ALA344A, ALA399C, ALA411C, ALA427C, ALA434C, ALA445C, ALA448C, ALA450C, ALA451C, ALA452C, ALA453C, ALA88A, ARG136A, ARG140A, ARG269A, ARG27A, ARG320C, ARG323A, ARG334A, ARG343C, ARG357C, ARG423C, ARG447C, ARG449C, ARG461C, ARG64A, ASN108A, ASN191A, ASN26A, ASN296A, ASN298A, ASN301A, ASN303A, ASN315A, ASN322A, ASN325A, ASN335A, ASN338A, ASN405C, ASN415C, ASN87A, ASP170A, ASP25A, ASP319A, ASP321C, ASP342A, ASP360C, ASP460C, ASP473C, ASP59A, ASP61A, CYS144A, CYS288C, GLN113A, GLN165A, GLN187A, GLN199A, GLN311C, GLN313C, GLN332C, GLU104A, GLU132A, GLU189A, GLU221C, GLU242A, GLU243A, GLU269C, GLU308C, GLU329A, GLU333A, GLU354C, GLU413C, GLU456C, GLU464C, GLU65A, GLU98A, GLY128A, GLY138A, GLY164A, GLY166A, GLY171A, GLY219C, GLY220C, GLY222C, GLY240A, GLY289A, GLY299A, GLY306C, GLY327A, GLY333C, GLY336C, GLY338C, GLY352C, GLY353C, GLY402C, GLY408C, GLY409C, GLY440C, GLY446C, GLY454C, GLY458C, GLY62A, GLY90A, HIS190A, HIS195A, HIS304A, HIS332A, HIS337A, HIS398C, HIS430C, HIS441C, HIS444C, HIS92A, ILE116A, ILE160A, ILE163A, ILE192A, ILE265C, ILE290A, ILE307A, ILE321A, ILE350C, ILE414C, ILE459C, ILE60A, ILE63A, ILE89A, LEU133A, LEU137A, LEU151A, LEU159A, LEU200A, LEU288A, LEU28A, LEU297A, LEU318C, LEU326A, LEU337C, LEU341A, LEU341C, LEU343A, LEU401C, LEU404C, LEU426C, LEU433C, LEU438C, LEU442C, LEU467C, LEU472C, LEU91A, LYS339C, LYS457C, MET127A, MET139A, MET194A, MET293A, MET315C, MET328A, MET342C, MET356C, MET396C, MET469C, PHE117A, PHE155A, PHE168A, PHE186A, PHE197A, PHE218C, PHE239A, PHE273A, PHE284C, PHE285A, PHE292C, PHE295A, PHE300A, PHE302A, PHE317C, PHE339A, PHE33A, PHE33C, PHE351C, PHE358C, PHE361C, PHE419C, PHE431C, PHE435C, PHE436C, PHE437C, PHE455C, PHE93A, PRO141A, PRO150A, PRO162A, PRO196A, PRO217C, PRO304C, PRO307C, PRO334C, PRO340A, PRO345C, PRO400C, PRO465C, PRO470C, PRO95A, SER124A, SER134A, SER148A, SER153A, SER167A, SER169A, SER216C, SER23A, SER291A, SER305A, SER310C, SER344C, SER403C, SER406C, SER416C, SER421C, SER424C, SER429C, SER463C, SER468C, SER471C, SER86A, THR24A, THR287C, THR292A, THR305C, THR316C, THR335C, THR346C, THR355C, THR397C, THR412C, THR428C, TRP131A, TRP142A, TRP284A, TRP291C, TRP32A, TRP359C, TRP36C, TRP425C, TRP443C, TYR135A, TYR147A, TYR161A, TYR29A, TYR340C, TYR395C, TYR94A, VAL145A, VAL185A, VAL280A, VAL281A, VAL283A, VAL290C, VAL306A, VAL313A, VAL328C, VAL330A, VAL407C, VAL410C, VAL417C, VAL420C, VAL432C, VAL439C, VAL466C
• A-D: ALA133D, ALA143D, ALA145D, ALA146A, ALA148D, ALA149A, ALA170D, ALA176D, ALA177D, ALA188A, ALA203A, ALA208D, ALA209A, ALA212D, ALA213A, ALA216D, ALA229D, ALA233A, ALA234D, ALA240D, ALA249D, ALA250A, ALA251A, ALA260D, ALA263A, ALA276A, ALA277A, ALA318A, ALA324A, ALA327D, ALA330D, ALA336A, ALA351D, ALA64D, ALA77D, ALA81A, ARG128D, ARG129A, ARG134D, ARG136A, ARG139D, ARG140A, ARG180D, ARG225A, ARG233D, ARG24D, ARG251D, ARG257A, ARG265D, ARG269A, ARG26D, ARG27A, ARG304D, ARG323A, ARG326D, ARG334A, ARG348D, ARG64A, ASN142D, ASN181A, ASN190D, ASN191A, ASN194D, ASN220D, ASN234A, ASN236D, ASN247A, ASN250D, ASN263D, ASN266A, ASN267A, ASN26A, ASN301A, ASN303A, ASN312A, ASN315A, ASN318D, ASN322A, ASN322D, ASN325A, ASN335A, ASN338A, ASN350D, ASN72D, ASN75A, ASN76A, ASP225D, ASP25A, ASP25D, ASP297D, ASP308A, ASP319A, ASP333D, ASP342A, ASP61A, CYS125A, CYS144A, CYS211D, CYS212A, CYS71D, GLN129D, GLN130A, GLN186D, GLN187A, GLN199A, GLN224D, GLN239D, GLN241A, GLN255D, GLN261A, GLN301D, GLN332D, GLN334D, GLU131D, GLU132A, GLU189A, GLU219D, GLU226A, GLU229A, GLU231A, GLU241D, GLU242A, GLU242D, GLU243A, GLU244A, GLU310D, GLU312D, GLU323D, GLU329A, GLU333A, GLU65A, GLU69D, GLY124D, GLY128A, GLY137D, GLY138A, GLY171A, GLY174D, GLY175A, GLY178A, GLY187D, GLY200D, GLY201A, GLY203D, GLY204A, GLY206D, GLY207A, GLY207D, GLY208A, GLY215D, GLY216A, GLY226D, GLY228D, GLY236A, GLY240A, GLY253A, GLY256A, GLY258D, GLY278D, GLY299A, GLY324D, GLY327A, GLY349D, GLY62D, GLY69A, GLY70D, GLY74A, GLY80A, HIS195A, HIS197D, HIS198A, HIS214D, HIS215A, HIS252A, HIS268D, HIS272A, HIS304A, HIS332A, HIS337A, HIS61D, ILE132D, ILE143A, ILE144D, ILE176A, ILE178D, ILE184A, ILE192A, ILE213D, ILE224A, ILE248A, ILE256D, ILE259A, ILE259D, ILE299D, ILE307A, ILE314A, ILE320A, ILE321A, ILE325D, ILE60A, ILE63A, ILE77A, ILE78A, LEU127D, LEU133A, LEU135D, LEU137A, LEU174A, LEU182D, LEU183D, LEU193A, LEU193D, LEU205D, LEU209D, LEU210A, LEU210D, LEU218A, LEU222D, LEU223A, LEU258A, LEU267D, LEU271A, LEU272D, LEU275A, LEU279D, LEU28A, LEU319D, LEU320D, LEU321D, LEU326A, LEU341A, LEU343A, LEU346D, LEU352D, LEU37D, LEU63D, LEU71A, LEU72A, LEU74D, LYS238A, LYS23D, LYS264D, LYS317D, MET126D, MET127A, MET139A, MET172A, MET183A, MET194A, MET198D, MET214A, MET246D, MET271D, MET328A, MET329D, MET331A, MET37A, PHE125D, PHE130D, PHE146D, PHE168D, PHE169D, PHE173D, PHE179D, PHE180A, PHE181D, PHE182A, PHE184D, PHE186A, PHE188D, PHE206A, PHE211A, PHE223D, PHE232D, PHE235D, PHE239A, PHE252D, PHE255A, PHE257D, PHE260A, PHE261D, PHE265A, PHE269D, PHE270D, PHE273A, PHE273D, PHE274A, PHE27D, PHE298D, PHE29D, PHE300A, PHE302A, PHE311D, PHE314D, PHE339A, PHE341D, PHE38D, PHE73D, PRO140D, PRO141A, PRO149D, PRO150A, PRO171D, PRO173A, PRO195D, PRO196A, PRO237D, PRO275D, PRO279A, PRO309D, PRO331D, PRO335D, PRO340A, PRO347D, PRO57A, PRO66A, PRO84A, SER134A, SER169A, SER172D, SER177A, SER217A, SER221A, SER222A, SER230D, SER232A, SER23A, SER245D, SER254D, SER262D, SER268A, SER270A, SER282D, SER295D, SER300D, SER305A, SER33D, SER57D, SER65D, SER66D, SER68A, SER70A, SER79D, THR179A, THR192D, THR217D, THR220A, THR221D, THR227A, THR22A, THR231D, THR238D, THR243D, THR245A, THR248D, THR24A, THR277D, THR313D, THR316A, THR316D, THR52D, THR56D, THR60D, THR75D, THR79A, THR80D, TRP111D, TRP131A, TRP142A, TRP191D, TRP253D, TRP266D, TRP278A, TRP317A, TRP328D, TRP58D, TYR126A, TYR135A, TYR141D, TYR147A, TYR235A, TYR237A, TYR244D, TYR246A, TYR254A, TYR262A, TYR29A, TYR315D, TYR73A, VAL136D, VAL138D, VAL145A, VAL152D, VAL175D, VAL185A, VAL201D, VAL202A, VAL204D, VAL205A, VAL218D, VAL219A, VAL247D, VAL249A, VAL274D, VAL276D, VAL280A, VAL281A, VAL283A, VAL28D, VAL306A, VAL30A, VAL30D, VAL313A, VAL330A, VAL58A, VAL67A, VAL76D, VAL78D, VAL82A, VAL83A
• A-E: ALA309A, ALA57E, ARG257A, ARG51E, ARG61E, ASN312A, ASN315A, ASP308A, ASP53E, GLN261A, GLN58E, GLN60E, GLU59E, GLU7E, GLY311A, GLY6E, ILE307A, ILE314A, ILE63E, LYS310A, PHE10E, PHE260A, PRO50E, PRO52E, PRO64E, PRO9E, SER54E, THR316A, THR4E, THR5E, TYR262A, TYR55E, TYR56E, VAL306A, VAL313A
• A-F: ALA309A, ARG19F, ARG45F, ASN312A, ASP308A, GLN44F, GLY311A, ILE307A, ILE314A, LYS310A, PHE260A, SER305A, TYR262A, VAL306A
• A-I: ALA100A, ALA29I, ALA43A, ALA99A, ARG129A, ARG136A, ARG16A, ARG30I, ARG34I, ASN19A, ASN31I, ASP27I, CYS125A, CYS18A, GLU132A, GLU15A, GLU2I, GLU98A, GLY128A, GLY138A, GLY22I, GLY26I, GLY31A, GLY34A, HIS118A, ILE36A, ILE38A, ILE6I, ILE96A, LEU102A, LEU114A, LEU121A, LEU133A, LEU137A, LEU17I, LEU18I, LEU24I, LEU37I, LEU4I, LYS33I, LYS35I, LYS5I, MET139A, MET1I, MET37A, PHE14I, PHE15I, PHE17A, PHE19I, PHE21I, PHE23I, PHE33A, PHE93A, PRO28I, PRO32I, PRO39A, PRO95A, SER101A, SER134A, SER23A, SER25I, THR13I, THR22A, THR24A, THR3I, THR40A, THR7I, TRP131A, TRP14A, TRP20A, TRP32A, TRP97A, TYR135A, TYR29A, TYR9I, VAL11I, VAL12I, VAL16I, VAL20I, VAL21A, VAL35A, VAL8I
• A-J: ALA309A, ALA32J, ASN301A, ASN303A, ASP308A, GLY311A, GLY35J, GLY37J, HIS304A, ILE307A, ILE314A, LEU36J, LEU40J, PHE29J, PHE300A, PHE302A, SER305A, SER38J, SER39J, THR316A, TYR33J, VAL306A, VAL313A
• A-L: ALA28L, ARG14L, ARG7L, ASN13L, ASN234A, ASN37L, ASN6L, ASN75A, ASN76A, GLN8L, GLU11L, GLU229A, GLU231A, GLY80A, ILE176A, ILE77A, ILE78A, LEU12L, LEU29L, LEU30L, LEU71A, PHE180A, PHE31L, PHE35L, PHE36L, PHE52A, PRO9L, SER16L, SER177A, SER232A, SER32L, SER33L, THR228A, THR230A, THR79A, TYR235A, TYR34L, VAL10L, VAL26L
• A-M: ASN75A, ASN76A, GLY74A, LEU71A, LEU72A, MET1M, THR29M, THR79A, TYR235A, TYR73A, VAL3M
• A-O: ALA100A, ALA111O, ALA336A, ALA55A, ALA88A, ALA99A, ARG115O, ARG152O, ARG162O, ARG334A, ARG64A, ARG73O, ASN108A, ASN155O, ASN335A, ASN338A, ASP103A, ASP158O, ASP59A, GLN104O, GLN109O, GLN113A, GLU104A, GLU114O, GLU333A, GLU65A, GLU74O, GLU98A, GLY109A, GLY112O, GLY113O, GLY12O, GLY161O, GLY167O, GLY62A, GLY90A, HIS92A, ILE116O, ILE172O, ILE63A, ILE89A, LEU102A, LEU106A, LEU118O, LEU119O, LEU157O, LEU70O, LYS160O, LYS69O, MET110O, MET331A, PHE120O, PHE156O, PHE93A, PRO105O, PRO117O, PRO159O, PRO56A, PRO57A, PRO66A, PRO95A, SER101A, SER166O, SER68A, SER85A, SER86A, THR107O, THR72O, THR75O, THR76O, TRP105A, TYR107A, TYR151O, TYR168O, TYR73A, TYR94A, VAL106O, VAL108O, VAL11O, VAL330A, VAL58A, VAL67A, VAL71O
• A-T: ALA11T, ALA20T, ALA54A, ARG24T, ARG27A, ARG28T, ASN75A, ASN76A, GLN241A, GLU242A, GLU25T, GLU2T, GLY240A, GLY74A, ILE14T, ILE21T, ILE29T, ILE46A, ILE4T, ILE53A, ILE77A, ILE78A, ILE9T, LEU28A, LEU71A, LEU72A, LYS238A, MET1T, PHE10T, PHE17T, PHE18T, PHE19T, PHE22T, PHE239A, PHE23T, PHE48A, PHE52A, PHE8T, PRO26T, PRO27T, SER70A, THR30T, THR3T, THR45A, THR5T, THR79A, TYR235A, TYR237A, TYR6T, TYR73A, VAL49A, VAL7T
• A-U: ASN338A, ASN99U, GLY101U, HIS337A, LEU102U, LEU341A, LYS104U, PHE339A, PRO340A, TYR103U, VAL330A
• A-V: ALA1V, ALA309A, ARG323A, ASN303A, ASN312A, ASN315A, ASN322A, ASN49V, ASP308A, ASP319A, ASP342A, CYS40V, GLU122V, GLU23V, GLU2V, GLU329A, GLY127V, GLY133V, GLY311A, GLY327A, GLY43V, HIS304A, HIS332A, ILE125V, ILE307A, ILE314A, ILE320A, ILE45V, LEU126V, LEU326A, LEU341A, LEU343A, LEU3V, LEU8V, LYS124V, LYS129V, LYS134V, LYS30V, LYS310A, LYS47V, PHE339A, PRO123V, PRO340A, PRO50V, SER39V, SER51V, THR46V, THR48V, THR4V, TYR136V, TYR137V, TYR26V, VAL121V, VAL135V, VAL313A, VAL330A, VAL42V, VAL7V
• A-b: ALA43b, ALA54A, ASP103A, GLY77b, ILE101b, ILE46A, ILE50A, ILE53A, LEU102A, LEU106A, LEU39b, LEU42b, LEU72A, LEU98b, SER76b, THR44b, TRP75b, TYR40b, TYR73A, VAL102b
• B-D: ALA133D, ALA143D, ALA145D, ALA148D, ALA151D, ALA170D, ALA228B, ALA253B, ALA283D, ALA290D, ALA320B, ALA327D, ALA330D, ALA351D, ALA361B, ALA379B, ALA386B, ALA454B, ALA456B, ALA459B, ALA471B, ARG12D, ARG134D, ARG139D, ARG180D, ARG224B, ARG230B, ARG24D, ARG265D, ARG26D, ARG272B, ARG294D, ARG326B, ARG326D, ARG348D, ARG357B, ARG358B, ARG384B, ARG385B, ARG444B, ARG448B, ARG472B, ARG476B, ARG7B, ASN190D, ASN194D, ASN292D, ASN318B, ASN322D, ASN338D, ASN350D, ASN438B, ASN83D, ASP16D, ASP19D, ASP20D, ASP25D, ASP276B, ASP297D, ASP333D, ASP380B, ASP440B, ASP477B, ASP483B, ASP501B, GLN129D, GLN164D, GLN223B, GLN334D, GLN394B, GLN395B, GLN490B, GLN497B, GLU11D, GLU131D, GLU302D, GLU323D, GLU337D, GLU343D, GLU344D, GLU364B, GLU387B, GLU489B, GLU492B, GLY137D, GLY13D, GLY163D, GLY187D, GLY254B, GLY285D, GLY288D, GLY31D, GLY322B, GLY323B, GLY324D, GLY333B, GLY349D, GLY375B, GLY441B, GLY449B, GLY465B, GLY470B, GLY481B, GLY494B, GLY500B, GLY86D, HIS189D, HIS197D, HIS336D, HIS455B, HIS466B, HIS469B, HIS87D, ILE123D, ILE132D, ILE144D, ILE150D, ILE159D, ILE17D, ILE284D, ILE299D, ILE303D, ILE315B, ILE325D, ILE369B, ILE381B, ILE442B, ILE467B, ILE482B, LEU122D, LEU127D, LEU135D, LEU158D, LEU162D, LEU18D, LEU193D, LEU22D, LEU272D, LEU279D, LEU289D, LEU291D, LEU293D, LEU319D, LEU320D, LEU324B, LEU346D, LEU352D, LEU370B, LEU460B, LEU461B, LEU474B, LEU486B, LYS227B, LYS23D, LYS321B, LYS332B, LYS378B, LYS389B, LYS498B, MET126D, MET199D, MET256B, MET281D, MET329D, MET359B, PHE130D, PHE146D, PHE153D, PHE15D, PHE168D, PHE169D, PHE181D, PHE184D, PHE185D, PHE188D, PHE196D, PHE250B, PHE269D, PHE273D, PHE27D, PHE298D, PHE29D, PHE325B, PHE339D, PHE341D, PHE362B, PHE363B, PHE366B, PHE383B, PHE392B, PHE443B, PHE451B, PHE453B, PHE458B, PHE462B, PHE463B, PHE464B, PHE475B, PHE479B, PHE495B, PRO140D, PRO149D, PRO161D, PRO195D, PRO237D, PRO319B, PRO331D, PRO342D, PRO347D, PRO360B, PRO367B, PRO382B, PRO484B, PRO488B, SER147D, SER155D, SER165D, SER166D, SER282D, SER295D, SER300D, SER365B, SER388B, SER391B, SER439B, SER446B, SER480B, THR238D, THR327B, THR371B, THR445B, THR452B, THR473B, THR503B, THR504B, TRP14D, TRP167D, TRP191D, TRP21D, TRP257B, TRP266D, TRP280D, TRP328D, TRP32D, TRP450B, TRP468B, TRP493B, TRP5B, TYR141D, TYR160D, TYR258B, TYR273B, TYR296D, TYR315D, TYR390B, TYR496B, TYR6B, VAL136D, VAL138D, VAL152D, VAL154D, VAL156D, VAL276D, VAL286D, VAL287D, VAL28D, VAL30D, VAL340D, VAL345D, VAL368B, VAL376B, VAL377B, VAL457B, VAL478B, VAL491B, VAL499B
• B-E: GLN497B, GLU492B, GLY494B, GLY6E, PHE495B, THR4E, THR5E, TRP493B, TYR496B, VAL499B
• B-H: ALA132B, ALA205B, ALA228B, ALA22H, ALA261B, ALA2H, ALA32H, ALA64H, ARG124B, ARG127B, ARG12H, ARG220B, ARG224B, ARG286B, ARG3H, ARG448B, ARG476B, ARG4H, ASN14B, ASN15H, ASN191B, ASN194B, ASN233B, ASN50H, ASN59H, ASP119B, ASP125B, ASP134B, ASP170B, ASP188B, ASP56H, ASP9H, GLN223B, GLN274B, GLN282B, GLU121B, GLU130B, GLU17H, GLU184B, GLU266B, GLU283B, GLY129B, GLY173B, GLY186B, GLY189B, GLY196B, GLY197B, GLY19H, GLY232B, GLY24H, GLY254B, GLY259B, GLY269B, GLY26H, GLY57H, GLY66H, GLY8H, HIS114B, HIS201B, HIS216B, ILE10H, ILE141B, ILE20B, ILE211B, ILE217B, ILE234B, ILE265B, ILE44H, ILE45H, ILE48H, LEU11H, LEU120B, LEU122B, LEU133B, LEU135B, LEU14H, LEU218B, LEU225B, LEU229B, LEU30H, LEU42H, LEU46H, LEU53H, LEU55H, LEU65H, LEU7H, LYS137B, LYS20H, LYS227B, LYS63H, MET138B, MET231B, MET256B, MET31H, PHE123B, PHE190B, PHE215B, PHE247B, PHE268B, PHE280B, PHE34H, PHE38H, PHE41H, PRO126B, PRO131B, PRO136B, PRO13H, PRO16B, PRO171B, PRO187B, PRO192B, PRO195B, PRO221B, PRO222B, PRO23H, PRO264B, PRO270B, PRO29H, SER169B, SER16H, SER260B, SER277B, SER51H, SER61H, THR128B, THR175B, THR255B, THR262B, THR263B, THR271B, THR27H, THR28H, THR5H, TRP113B, TRP118B, TRP167B, TRP257B, TRP25H, TRP62H, TYR117B, TYR172B, TYR18H, TYR193B, TYR226B, TYR258B, TYR273B, TYR279B, TYR49H, VAL116B, VAL168B, VAL181B, VAL208B, VAL219B, VAL21H, VAL251B, VAL58H, VAL60H
• B-L: ARG124B, ARG18B, ARG326B, ARG444B, ARG7B, ARG7L, ASN13L, ASN14B, ASN37L, ASN4L, ASN6L, ASP119B, ASP15B, ASP440B, GLN8L, GLU11L, GLU2L, GLY17B, GLY20L, GLY2B, GLY323B, HIS114B, HIS9B, ILE13B, ILE442B, LEU12B, LEU12L, LEU19B, LEU23L, LEU30L, LEU324B, LEU3B, MET1L, PHE31L, PHE325B, PHE35L, PHE36L, PRO131B, PRO16B, PRO3L, PRO4B, PRO5L, PRO9L, SER16L, SER33L, THR10B, THR327B, TRP115B, TRP118B, TRP5B, TYR117B, TYR34L, TYR6B, VAL10L, VAL116B, VAL11B, VAL8B
• B-M: ARG326B, ARG444B, ARG7B, ASN438B, ASN4M, ASP440B, GLN28M, GLN32M, GLN5M, GLU2M, GLY2B, LEU22M, LEU25M, LEU3B, LEU6M, LYS332B, PHE21M, PHE325B, PRO4B, THR29M, THR327B, TRP5B, TYR40B, TYR6B, VAL3M, VAL8B
• B-O: ALA154O, ALA165O, ALA171O, ALA173O, ALA177O, ALA386B, ARG162O, ARG326B, ARG384B, ARG385B, ARG422B, ARG57B, ASN155O, ASN186O, ASP169O, ASP334B, ASP433B, ASP440B, GLN176O, GLN338B, GLU179O, GLU180O, GLU181O, GLU364B, GLU387B, GLU428B, GLU431B, GLU435B, GLY161O, GLY163O, GLY167O, GLY316B, GLY333B, GLY335B, GLY441B, ILE172O, ILE315B, ILE336B, ILE381B, ILE425B, ILE429B, ILE442B, LEU157O, LEU164O, LEU174O, LEU182O, LYS160O, LYS178O, LYS188O, LYS321B, LYS341B, LYS418B, LYS423B, MET359B, PHE311B, PHE363B, PHE366B, PHE383B, PHE426B, PHE430B, PHE432B, PHE443B, PRO175O, PRO367B, PRO382B, PRO415B, SER166O, SER170O, SER365B, SER419B, SER439B, THR416B, THR434B, THR436B, TYR168O, TYR314B, TYR420B, VAL187O, VAL368B
• B-U: ALA20U, ALA33U, ALA34U, ALA386B, ARG384B, ARG385B, ARG422B, ASN100U, ASN11U, ASN31U, ASP14U, ASP96U, GLN37U, GLN394B, GLN395B, GLU15U, GLU23U, GLU387B, GLU393B, GLU8U, GLY101U, GLY18U, GLY22U, GLY396B, ILE381B, LEU102U, LEU17U, LEU91U, LEU9U, LYS104U, LYS16U, LYS24U, LYS349B, LYS389B, LYS418B, PHE383B, PHE392B, PRO382B, PRO414B, PRO415B, SER388B, SER391B, THR19U, THR30U, TYR103U, TYR21U, TYR390B, VAL10U, VAL12U, VAL13U
• B-V: ARG384B, GLU387B, LYS134V, LYS389B, SER51V, TYR136V, VAL135V
• B-X: ARG39X, ARG505B, ASP35X, ASP501B, GLN38X, GLN497B, LEU7X, LYS36X, LYS498B, PRO187B, SER40X, THR2X, THR503B, THR504B, TYR496B, VAL37X, VAL499B, VAL502B
• B-a: ALA43B, ALA54a, ASP103a, GLY77B, ILE46a, ILE50a, ILE53a, LEU102a, LEU106a, LEU39B, LEU42B, LEU72a, LEU98B, SER76B, THR44B, TRP75B, TYR40B, TYR73a, VAL102B
• B-o: ALA111o, ALA337B, ALA339B, ARG60o, ASN53B, ASN58o, ASP433B, ASP49B, ASP87B, GLN109o, GLN338B, GLN61o, GLU114o, GLU307B, GLU405B, GLU431B, GLU54o, GLU55o, GLU64o, GLU83B, GLY112o, GLY113o, GLY404B, GLY77B, GLY82B, GLY85B, ILE305B, ILE86B, LEU309B, LEU406B, LEU52B, LYS308B, LYS57o, LYS59o, LYS69o, MET110o, PHE430B, PHE432B, PHE65o, PRO306B, PRO47B, PRO50B, PRO56o, PRO67o, PRO88B, SER303B, SER48B, SER74B, SER76B, SER79B, THR68o, THR84B, TRP340B, TRP75B, TRP78B, VAL51B, VAL66o
• B-t: ALA111B, ALA15t, ALA43B, ARG18B, CYS112B, ILE4t, LEU109B, LEU39B, MET1t, MET25B, PHE108B, PHE18t, PHE19t, PHE22t, PHE23t, SER36B, THR3t, THR44B, TRP113B, TRP115B, TYR40B, VAL116B, VAL7t
• C-D: ALA229D, ALA234D, ALA240D, ALA249D, ALA260D, ALA34C, ALA351D, ALA37C, ALA40C, ALA451C, ARG233D, ARG251D, ARG41C, ARG447C, ARG461C, ASN220D, ASN236D, ASN250D, ASN350D, ASN405C, ASN72D, ASP225D, ASP27C, ASP460C, ASP473C, GLN224D, GLN239D, GLN255D, GLN28C, GLN313C, GLU219D, GLU227D, GLU241D, GLU242D, GLU29C, GLU354C, GLU456C, GLU462C, GLU464C, GLY226D, GLY228D, GLY258D, GLY32C, GLY333C, GLY454C, GLY458C, ILE256D, ILE43C, ILE459C, LEU222D, LEU352D, LEU404C, LEU467C, LEU472C, LEU74D, LYS339C, LYS457C, MET246D, MET469C, PHE223D, PHE232D, PHE235D, PHE252D, PHE33C, PHE455C, PRO334C, PRO465C, PRO470C, SER230D, SER245D, SER254D, SER30C, SER31C, SER463C, SER468C, SER471C, THR221D, THR231D, THR243D, THR248D, THR335C, TRP253D, TRP35C, TRP36C, TRP443C, TYR244D, VAL247D, VAL410C, VAL466C
• C-I: ALA260C, ALA263C, ALA29I, ALA448C, ALA450C, ALA451C, ALA452C, ALA453C, ARG261C, ARG262C, ARG30I, ARG34I, ARG449C, ARG461C, ASN31I, ASP27I, ASP36I, ASP460C, GLU38I, GLU456C, GLU462C, GLU464C, GLY258C, GLY26I, GLY454C, GLY458C, ILE265C, ILE459C, LEU24I, LEU37I, LYS152C, LYS154C, LYS33I, LYS35I, MET469C, PHE23I, PHE264C, PHE455C, PRO256C, PRO28I, PRO32I, PRO465C, SER216C, SER25I, SER267C, SER463C, SER468C, TRP259C, TRP266C, TYR274C, TYR9I, VAL20I, VAL466C
• C-J: ALA32J, ASN405C, ASN415C, ASN418C, GLY37J, ILE414C, LEU404C, LEU40J, PHE29J, SER38J, SER39J, SER406C, SER416C, TYR33J, VAL407C, VAL417C
• C-K: ALA14K, ALA16K, ALA23C, ALA34C, ALA36K, ALA37C, ALA55C, ALA64C, ALA66C, ALA73C, ARG26C, ARG41C, ARG46K, ASN25C, ASN39C, ASP19K, ASP23K, ASP27C, GLN28C, GLN40K, GLN84C, GLU29C, GLU71C, GLU78C, GLY115C, GLY126C, GLY38C, GLY44K, GLY58C, GLY65C, HIS56C, HIS74C, ILE134C, ILE28K, ILE60C, ILE76C, ILE89C, LEU119C, LEU11K, LEU21K, LEU25K, LEU31K, LEU33K, LEU42C, LEU59C, LEU69C, LEU72C, LEU88C, LYS10K, LYS48C, MET67C, PHE109C, PHE111C, PHE112C, PHE18K, PHE32K, PHE33C, PHE37K, PHE45K, PHE62C, PHE70C, PHE75C, PRO12K, PRO20K, PRO26K, PRO29K, PRO77C, SER122C, SER30C, SER31C, THR108C, THR24C, THR68C, TRP35C, TRP36C, TRP39K, TRP63C, TYR15K, VAL113C, VAL116C, VAL130C, VAL22K, VAL24K, VAL27K, VAL30K, VAL43K, VAL61C
• C-L: ARG14L, ASP473C
• C-O: ALA154O, ALA16O, ALA326C, ALA331C, ALA41O, ARG152O, ARG343C, ARG362C, ARG370C, ARG39O, ARG42O, ARG73O, ASN124O, ASN155O, ASN17O, ASN228C, ASN327C, ASN373C, ASN378C, ASN382C, ASP102O, ASP360C, ASP376C, ASP79O, ASP8O, ASP99O, ASP9O, CYS19O, CYS44O, GLN104O, GLN322C, GLN332C, GLN46O, GLN80O, GLN82O, GLU221C, GLU348C, GLU367C, GLU74O, GLU97O, GLU98O, GLY100O, GLY12O, GLY14O, GLY220C, GLY329C, GLY333C, GLY336C, GLY338C, GLY347C, GLY371C, GLY374C, ILE101O, ILE10O, ILE349C, ILE350C, ILE380C, ILE81O, LEU118O, LEU119O, LEU157O, LEU15O, LEU337C, LEU341C, LEU375C, LEU377C, LEU45O, LEU5O, LEU78O, LYS123O, LYS18O, LYS339C, LYS379C, LYS381C, MET225O, MET342C, PHE103O, PHE120O, PHE156O, PHE190O, PHE361C, PRO105O, PRO117O, PRO149O, PRO20O, PRO334C, PRO345C, PRO372C, PRO47O, SER150O, SER330C, SER344C, SER77O, THR121O, THR13O, THR153O, THR335C, THR346C, THR4O, THR6O, THR72O, THR75O, THR76O, TRP359C, TYR151O, TYR340C, TYR7O, VAL106O, VAL11O, VAL328C
• C-T: ARG24T, ARG28T, ASP473C, GLU25T, GLU464C, ILE21T, ILE29T, LEU467C, LEU472C, PHE22T, PHE23T, PRO26T, PRO27T, PRO470C, SER471C, VAL466C
• C-U: ALA326C, ALA331C, ALA33U, ALA46U, ARG320C, ARG97U, ASN100U, ASN31U, ASN327C, ASN99U, ASP321C, ASP96U, GLN313C, GLN322C, GLN332C, GLU93U, GLY101U, GLY325C, GLY333C, GLY336C, GLY338C, GLY94U, GLY95U, ILE32U, ILE36U, LEU102U, LEU318C, LEU324C, LEU337C, LEU48U, LYS104U, LYS323C, LYS339C, LYS47U, LYS51U, MET396C, PHE317C, PHE35U, PRO334C, PRO43U, SER330C, THR44U, TYR103U, TYR340C, TYR42U, TYR98U, VAL328C, VAL50U
• C-V: ALA312C, ALA36V, ALA38V, ALA392C, ALA393C, ALA399C, ALA411C, ALA89V, ALA98V, ARG105V, ARG31V, ARG320C, ARG390C, ARG391C, ASN106V, ASN415C, ASN418C, ASN49V, ASP321C, ASP99V, CYS37V, CYS40V, GLN313C, GLN34V, GLN385C, GLN388C, GLN84C, GLN86V, GLU104C, GLU389C, GLU394C, GLU413C, GLU78C, GLU83C, GLU90V, GLY131V, GLY133V, GLY408C, GLY409C, GLY43V, GLY44V, HIS118V, HIS398C, HIS41V, HIS92V, ILE100V, ILE319C, ILE384C, ILE414C, ILE45V, ILE76C, ILE88V, LEU107V, LEU126V, LEU324C, LEU52V, LYS103V, LYS129V, LYS134V, LYS30V, LYS323C, LYS47V, LYS79C, MET104V, MET396C, PHE101V, PHE317C, PHE33V, PHE419C, PRO102V, PRO386C, PRO50V, PRO77C, PRO80C, PRO93V, SER39V, SER416C, SER51V, SER97V, THR316C, THR397C, THR412C, THR46V, THR48V, THR81V, TRP130V, TRP387C, TYR136V, TYR137V, TYR35V, TYR395C, TYR82C, VAL105C, VAL106C, VAL407C, VAL410C, VAL417C, VAL42V, VAL91V
• C-Y: ALA133C, ALA23C, ARG135C, ARG26C, ASN45Y, GLN21Y, GLU138C, GLY44Y, HIS74C, ILE134C, ILE28Y, ILE35Y, LEU39Y, LEU46Y, LYS48C, PHE62C, PHE70C, THR24C, VAL130C
• C-Z: ALA123C, ALA133C, ALA26Z, ALA28Z, ARG135C, ARG26C, ASN58Z, ASP32Z, ASP34Z, GLN31Z, GLY126C, GLY128C, GLY129C, GLY136C, GLY43Z, GLY55Z, HIS132C, ILE120C, ILE134C, ILE40Z, ILE48Z, LEU119C, LEU12Z, LEU50Z, LEU52Z, LEU9Z, LYS37Z, MET19Z, PHE109C, PHE112C, PHE127C, PHE41Z, PHE59Z, PHE5Z, PHE62C, PRO24Z, PRO30Z, SER121C, SER122C, SER16Z, SER29Z, SER36Z, SER44Z, THR108C, TRP33Z, TRP47Z, TYR131C, TYR27Z, VAL113C, VAL116C, VAL117C, VAL124C, VAL130C, VAL13Z, VAL20Z, VAL23Z, VAL25Z, VAL51Z, VAL54Z, VAL62Z
• C-l: ASP473C, MET1l
• D-E: ALA43E, ALA57E, ALA64D, ALA72E, ALA82D, ALA97D, ARG103D, ARG24D, ARG26D, ARG51E, ARG61E, ARG69E, ARG8E, ASN338D, ASN83D, ASP100D, ASP25D, ASP45E, ASP68E, CYS105D, CYS71D, GLN106D, GLN332D, GLN334D, GLN60E, GLN74E, GLN75E, GLN98D, GLU337D, GLU69D, GLU71E, GLU77E, GLU7E, GLU81E, GLU96D, GLY108D, GLY34E, GLY41E, GLY47D, GLY48E, GLY51D, GLY62D, GLY6E, GLY70D, GLY86D, GLY94D, GLY99D, HIS336D, HIS61D, HIS87D, ILE63E, LEU107D, LEU110D, LEU42E, LEU63D, LEU65E, LEU68D, LEU80E, LEU83E, LEU89D, LEU90D, LEU91D, LYS73E, MET85D, PHE101D, PHE10E, PHE168D, PHE27D, PHE29D, PHE37E, PHE47E, PHE54D, PHE70E, PHE79E, PRO335D, PRO50E, PRO52E, PRO64E, PRO81D, PRO95D, PRO9E, SER166D, SER39E, SER54E, SER57D, SER62E, SER65D, SER66D, SER84D, SER88D, THR102D, THR49E, THR4E, THR50D, THR53D, THR56D, THR5E, THR60D, THR67E, THR78E, TRP104D, TRP167D, TRP58D, TYR44E, TYR55E, TYR56E, TYR59D, TYR67D, VAL28D, VAL38E, VAL46E, VAL55D, VAL66E, VAL76E
• D-F: ALA22F, ALA27F, ALA36F, ALA38F, ALA39F, ALA41D, ARG19F, ARG24D, ARG26D, ARG45F, ASN72D, CYS71D, GLN41F, GLU69D, GLY31D, GLY35F, GLY46D, GLY47D, GLY51D, GLY70D, HIS24F, ILE37F, ILE43F, LEU22D, LEU26F, LEU34F, LEU45D, LEU49D, LEU68D, MET40F, PHE27D, PHE29D, PHE32F, PHE33F, PHE38D, PHE54D, PRO14F, PRO29F, SER66D, THR17F, THR25F, THR30F, THR50D, THR52D, THR53D, TRP20F, TRP21D, TRP48D, TYR42D, TYR67D, VAL18F, VAL21F, VAL23F, VAL28D, VAL28F, VAL30D, VAL55D, VAL76D
• D-H: ARG12D, ASN50H, ASP16D, ASP19D, GLU11D, GLU47H, GLU96D, GLY13D, GLY24H, GLY86D, GLY94D, HIS87D, ILE48H, ILE54H, LEU116D, LEU162D, LEU39H, LEU43H, LEU46H, LEU53H, LEU89D, LEU90D, LEU91D, MET85D, PHE120D, PHE15D, PRO29H, PRO95D, SER51H, SER88D, THR112D, THR28H, THR52H, TRP14D, TRP167D, TRP25H, TRP32D, TRP93D, TYR49H
• D-I: GLN224D, LYS33I
• D-J: ALA32J, ALA34J, ALA64D, ASN72D, CYS71D, GLU69D, GLY31J, GLY35J, GLY37J, GLY70D, LEU36J, LEU68D, PHE28J, PHE29J, PHE73D, SER38J, SER39J, SER66D, THR75D, TYR67D
• D-K: ARG233D, ARG46K, GLY44K, PHE45K
• D-L: ALA202D, ALA260D, ARG294D, ASN13L, ASN190D, ASN194D, ASN263D, ASN37L, ASP297D, GLN301D, GLU302D, GLY200D, HIS197D, ILE259D, ILE284D, ILE299D, ILE303D, LEU193D, LEU19L, LEU22L, LEU23L, LEU27L, LEU30L, MET198D, MET199D, MET281D, PHE196D, PHE261D, PHE270D, PHE273D, PHE298D, PHE31L, PHE35L, PHE36L, PRO195D, SER16L, SER262D, SER295D, SER300D, SER32L, SER33L, THR15L, THR192D, THR277D, TRP266D, TYR18L, TYR296D, TYR315D, TYR34L, VAL26L
• D-M: ALA305D, ARG304D, ASN4M, GLN301D, GLU2M, GLU302D, GLU307D, ILE299D, ILE303D, MET199D, MET1M, PHE14M, PHE298D, PHE311D, SER300D, THR313D, VAL3M
• D-O: ALA171O, ALA173O, ALA177O, ALA185O, ALA227O, ALA305D, ALA306D, ALA327D, ALA351D, ARG115O, ARG152O, ARG162O, ARG184O, ARG304D, ARG326D, ARG348D, ASN155O, ASN186O, ASN318D, ASN322D, ASN350D, ASP158O, ASP222O, ASP223O, ASP224O, ASP297D, ASP308D, GLN301D, GLU181O, GLU302D, GLU307D, GLU310D, GLU312D, GLU323D, GLU344D, GLY161O, GLY167O, GLY226O, GLY324D, GLY349D, HIS228O, ILE172O, ILE299D, ILE303D, LEU157O, LEU174O, LEU182O, LEU319D, LEU320D, LEU321D, LEU346D, LYS160O, LYS188O, LYS317D, MET225O, PHE156O, PHE298D, PHE311D, PRO117O, PRO159O, PRO175O, PRO309D, PRO347D, SER166O, SER170O, SER300D, THR153O, THR313D, THR316D, TYR151O, TYR168O, TYR296D, TYR315D, VAL345D
• D-T: ALA20T, ALA260D, ARG24T, ARG251D, ARG28T, ASN250D, ASN263D, GLN255D, GLU25T, GLU2T, GLY258D, ILE21T, ILE259D, ILE29T, LEU16T, MET246D, PHE17T, PHE19T, PHE22T, PHE257D, PHE261D, PHE298D, PRO26T, PRO27T, SER254D, SER262D, SER300D, THR248D, THR30T, TRP253D, TYR6T, VAL247D
• D-U: ALA351D, ARG348D, ASN100U, ASN350D, ASN99U, GLU343D, GLU344D, GLY101U, GLY349D, LEU102U, LEU17U, LEU346D, LEU352D, LYS104U, TRP328D, TYR103U
• D-V: ALA351D, ARG348D, ASN350D, ASP128V, GLN332D, GLU343D, GLU344D, GLY132V, GLY133V, LEU346D, LEU352D, LYS129V, LYS134V, PHE341D, PRO342D, PRO50V, TRP328D, TYR136V, TYR137V, VAL135V, VAL340D
• D-X: ALA26X, ALA30X, ARG12D, ARG24D, ARG26D, ARG39X, ASP16D, ASP19D, ASP20D, ASP25D, ASP35X, GLN33X, GLN38X, GLN98D, GLU96D, GLY13D, GLY13X, GLY17X, GLY31D, GLY34D, GLY94D, GLY99D, GLY9X, HIS117D, ILE12X, ILE17D, ILE29X, ILE31X, ILE34X, ILE35D, LEU14X, LEU18D, LEU21X, LEU22D, LEU28X, LEU36D, LEU43D, LEU7X, LEU91D, LEU92D, LYS23D, LYS36X, LYS8X, PHE10X, PHE11X, PHE15D, PHE25X, PRO39D, PRO5X, PRO95D, SER16X, SER32X, SER6X, THR24X, THR4X, TRP14D, TRP21D, TRP32D, TRP93D, VAL20X, VAL27X, VAL30D, VAL37X
• E-F: ALA22F, ALA27F, ALA29E, ALA33E, ALA36F, ALA38F, ALA39F, ALA43E, ARG18E, ARG19F, ARG45F, ARG51E, ARG8E, ASP12E, ASP53E, GLN41F, GLN44F, GLU7E, GLY34E, GLY35F, GLY41E, GLY6E, HIS23E, HIS24F, ILE13E, ILE14E, ILE15F, ILE22E, ILE27E, ILE31F, ILE32E, ILE37F, ILE43F, LEU30E, LEU34F, LEU36E, LEU42E, MET40F, PHE10E, PHE16F, PHE31E, PHE32F, PHE33F, PHE37E, PHE42F, PHE47E, PRO14F, PRO28E, PRO29F, PRO52E, PRO9E, SER11E, SER12F, SER39E, THR17F, THR26E, THR30F, THR40E, THR49E, THR4E, THR5E, TRP20F, TRP35E, TYR13F, TYR19E, TYR44E, TYR55E, VAL18F, VAL23F, VAL28F, VAL38E, VAL46E
• E-H: ARG69E, ASN50H, GLU47H, ILE48H, ILE54H, LEU53H, PHE70E, SER51H, THR52H, TYR49H, VAL60H
• E-J: ALA14J, ALA17J, ARG18E, ARG51E, ARG7J, ARG8E, ASP12E, ASP53E, GLU4J, GLY5J, GLY6J, ILE12J, ILE13E, ILE14E, ILE24J, ILE8J, LEU10J, LEU27J, LEU36J, PHE10E, PHE28J, PHE31E, PRO50E, PRO52E, PRO9E, PRO9J, SER11E, SER16E, SER3J, THR15E, TRP11J, TRP20E, TRP35E, TYR19E, TYR44E, TYR55E, VAL13J, VAL16J, VAL17E, VAL21E, VAL23J
• E-V: ALA1V, ALA57E, ARG51E, ARG61E, ASP128V, ASP53E, GLN58E, GLN60E, GLU122V, GLU2V, GLU59E, GLU6V, GLY127V, ILE125V, ILE63E, LEU126V, LEU3V, LEU83E, LEU8V, LYS124V, LYS129V, PRO123V, PRO52E, PRO5V, SER54E, THR4V, TRP130V, TYR55E, TYR56E, VAL121V, VAL7V
• E-X: PHE70E, SER6X
• F-J: ALA32J, ALA34J, ALA36F, ALA38F, ALA39F, ARG45F, GLN41F, GLN44F, GLY20J, GLY26J, GLY31J, GLY35F, GLY35J, GLY37J, ILE24J, ILE31F, ILE37F, ILE43F, LEU27J, LEU34F, LEU36J, LEU40J, MET40F, PHE28J, PHE29J, PHE33F, PHE42F, SER38J, SER39J, TYR30J, TYR33J, VAL21J, VAL25J
• F-V: ALA1V, ARG45F, GLN44F, GLU122V, GLU23V, GLU2V, HIS118V, ILE125V, LEU27V, LEU3V, LYS30V, TYR26V
• F-Y: LEU22Y, PHE42F, VAL18Y
• F-X: ASP35X, ILE31X, LEU28X, THR17F, VAL18F, VAL21F
• H-L: ALA2H, ARG3H, GLU2L, MET1L
• H-X: ALA18X, ASP56H, GLU47H, GLY13X, GLY36H, GLY57H, GLY9X, ILE3X, ILE44H, ILE45H, ILE48H, ILE54H, LEU14X, LEU21X, LEU37H, LEU39H, LEU42H, LEU43H, LEU46H, LEU53H, LEU55H, LEU7X, LYS8X, PHE10X, PHE11X, PHE41H, PRO5X, SER51H, SER6X, THR2X, THR4X, THR52H, VAL40H, VAL58H
• J-K: ALA14J, ALA34K, ALA41K, ALA42K, GLN40K, GLY18J, GLY44K, ILE12J, ILE22J, LEU10J, LEU31K, LEU35K, MET19J, PHE37K, PHE45K, PRO9J, THR15J, TRP11J, TRP39K, VAL16J, VAL27K, VAL30K, VAL38K, VAL43K
• J-V: ARG31V, GLN34V, LEU27V, LEU40J, LYS30V, SER39J, TYR26V
• J-Y: ALA26Y, ALA31Y, ALA40Y, GLY26J, GLY29Y, GLY32Y, ILE12J, ILE22J, ILE25Y, ILE28Y, ILE30Y, ILE35Y, ILE36Y, ILE8J, LEU22Y, LEU27J, LEU38Y, LEU39Y, LEU46Y, MET19J, MET34Y, PHE37Y, PRO33Y, PRO9J, THR15J, TRP11J, TYR30J, VAL16J, VAL18Y, VAL23J, VAL41Y
• K-Y: ALA20Y, ALA26Y, ALA31Y, ALA34K, ALA36K, ALA40Y, ALA41K, ALA42K, ARG46K, ASN45Y, ASP19K, ASP23K, GLN21Y, GLN40K, GLY29Y, GLY32Y, GLY44K, GLY44Y, ILE17K, ILE19Y, ILE25Y, ILE28K, ILE28Y, ILE30Y, ILE35Y, ILE36Y, LEU21K, LEU22Y, LEU25K, LEU31K, LEU35K, LEU39Y, LEU46Y, MET24Y, MET27Y, MET34Y, PHE18K, PHE32K, PHE37K, PHE37Y, PRO20K, PRO33Y, THR23Y, TRP39K, VAL18Y, VAL22K, VAL24K, VAL27K, VAL30K, VAL38K, VAL43K
• K-Z: ALA10Z, ALA11Z, ALA14K, ALA16K, ALA8Z, ASN58Z, GLN6Z, GLU13K, GLY55Z, ILE14Z, ILE17K, ILE28K, LEU11K, LEU12Z, LEU21K, LEU25K, LEU35K, LEU57Z, LEU7Z, LEU9Z, PHE17Z, PHE18K, PHE32K, PHE59Z, PHE5Z, PHE60Z, PRO12K, PRO24Z, SER16Z, THR2Z, TYR15K, VAL13Z, VAL20Z, VAL54Z, VAL61Z, VAL62Z
• L-M: ALA10M, ALA12M, ALA28L, ARG14L, ASN13L, ASN37L, ASN4M, GLN28M, GLN32M, GLN5M, GLN8L, GLU11L, GLU2M, GLU30M, GLY20L, GLY7M, ILE23M, ILE24L, ILE24M, ILE9M, LEU12L, LEU13M, LEU16M, LEU17L, LEU19L, LEU21L, LEU22L, LEU22M, LEU23L, LEU25L, LEU25M, LEU27L, LEU29L, LEU30L, LEU6M, LEU8M, LYS34M, MET1M, PHE14M, PHE21M, PHE31L, PHE35L, PHE36L, PRO18M, PRO9L, SER16L, SER19M, SER32L, SER33L, THR11M, THR15L, THR29M, TYR18L, TYR26M, TYR34L, VAL10L, VAL15M, VAL17M, VAL20M, VAL26L, VAL27M, VAL3M
• L-T: ALA11T, ALA15T, ALA20T, ALA28L, ARG14L, ARG24T, ASN13L, ASN37L, CYS12T, GLU25T, GLU2T, GLY20L, ILE13T, ILE14T, ILE21T, ILE24L, ILE4T, ILE9T, LEU12L, LEU16T, LEU17L, LEU19L, LEU21L, LEU22L, LEU23L, LEU25L, LEU27L, LEU29L, LEU30L, MET1T, PHE10T, PHE17T, PHE18T, PHE19T, PHE22T, PHE23T, PHE31L, PHE35L, PHE36L, PHE8T, PRO26T, SER16L, SER32L, SER33L, THR15L, THR3T, THR5T, TYR18L, TYR34L, TYR6T, VAL26L, VAL7T
• L-c: ASP473c, MET1L
• L-l: ARG14L, ARG14l, ARG7L, ARG7l
• L-m: ARG7L, GLU30m, ILE9m, LYS34m, PHE36L, PRO9L, SER31m, VAL10L, VAL27m
• L-t: ARG28t, MET1L, PRO26t
• M-T: ALA10M, ALA12M, ASN4M, CYS12T, GLN5M, GLU25T, GLU2M, GLU2T, GLU30M, GLY7M, ILE4T, ILE9M, ILE9T, LEU16M, LEU16T, LEU8M, MET1M, MET1T, PHE14M, PHE23T, PHE8T, SER19M, THR11M, THR3T, THR5T, TYR26M, TYR6T, VAL15M, VAL3M
• M-l: ARG7l, GLU30M, ILE9M, LYS34M, PHE36l, PRO9l, SER31M, VAL10l, VAL27M
• M-m: ALA10M, ALA10m, ALA12M, ALA12m, GLN28M, GLN28m, GLN32M, GLN32m, GLN33M, GLN33m, GLN5M, GLN5m, GLU30M, GLU30m, GLY7M, GLY7m, ILE23M, ILE23m, ILE24M, ILE24m, ILE9M, ILE9m, LEU13M, LEU13m, LEU16M, LEU16m, LEU22M, LEU22m, LEU25M, LEU25m, LEU6M, LEU6m, LEU8M, LEU8m, LYS34M, LYS34m, PHE14m, PHE21M, PHE21m, PRO18m, SER19M, SER19m, SER31M, SER31m, THR11M, THR11m, THR29M, THR29m, TYR26M, TYR26m, VAL15M, VAL15m, VAL17M, VAL17m, VAL20M, VAL20m, VAL27M, VAL27m
• M-t: GLN5M, ILE9M, LEU6M, MET1t, THR5t
• O-U: ALA154O, ALA165O, ALA183O, ALA185O, ALA227O, ALA90U, ARG152O, ARG184O, ARG189O, ASN100U, ASN11U, ASN124O, ASN147O, ASN155O, ASN186O, ASN99U, ASP14U, ASP169O, ASP96U, GLU15U, GLU180O, GLU88U, GLU8U, GLU93U, GLU98O, GLY101U, GLY163O, GLY167O, GLY226O, GLY94U, GLY95U, LEU102U, LEU119O, LEU164O, LEU17U, LEU182O, LEU192O, LEU91U, LEU9U, LYS123O, LYS188O, LYS51U, MET225O, PHE103O, PHE156O, PHE190O, PRO149O, SER150O, SER166O, SER191O, THR153O, THR193O, THR89U, TYR168O, TYR21U, VAL10U, VAL12U, VAL13U, VAL148O, VAL187O, VAL87U, VAL92U
• O-b: ALA111O, ALA337b, ALA339b, ARG60O, ASN53b, ASN58O, ASP433b, ASP49b, ASP87b, GLN109O, GLN338b, GLN61O, GLU114O, GLU307b, GLU405b, GLU431b, GLU54O, GLU55O, GLU64O, GLU83b, GLY112O, GLY113O, GLY404b, GLY77b, GLY82b, GLY85b, ILE305b, ILE86b, LEU309b, LEU52b, LYS308b, LYS341b, LYS57O, LYS59O, LYS69O, MET110O, PHE430b, PHE432b, PHE65O, PRO306b, PRO47b, PRO50b, PRO56O, PRO67O, PRO88b, SER303b, SER48b, SER74b, SER76b, SER79b, THR68O, THR84b, TRP340b, TRP75b, TRP78b, VAL51b, VAL52O, VAL66O
• T-b: ALA111b, ALA15T, ALA43b, ARG18b, CYS112b, ILE4T, LEU109b, LEU39b, MET1T, MET25b, PHE108b, PHE18T, PHE19T, PHE22T, PHE23T, SER36b, THR3T, THR44b, TRP113b, TRP115b, TYR40b, VAL116b, VAL7T
• T-l: ARG28T, MET1l, PRO26T
• T-m: GLN5m, ILE4T, ILE9m, LEU6m, MET1T, THR5T
• U-V: ALA33U, ALA34U, ALA46U, ALA60V, ALA62V, ARG39U, ARG55V, ARG66V, ARG70U, ASN100U, ASN31U, ASN49V, ASN99U, ASP128V, ASP53V, ASP67V, ASP83V, GLN37U, GLN71U, GLN86V, GLU57V, GLU85V, GLY131V, GLY132V, GLY133V, GLY40U, GLY44V, GLY84V, ILE32U, ILE36U, ILE45V, ILE74U, ILE88V, LEU102U, LEU41U, LEU45U, LEU48U, LEU52V, LEU54V, LEU59V, LEU61V, LYS104U, LYS134V, LYS47U, LYS47V, PHE35U, PRO43U, PRO50V, PRO64V, PRO65V, SER14V, SER51V, THR44U, THR46V, THR48V, THR58V, THR63V, THR68U, THR80V, THR81V, TRP130V, TYR103U, TYR136V, TYR137V, TYR38U, TYR42U, TYR82V, TYR98U, VAL135V
• Y-Z: ALA26Y, ALA26Z, ALA28Z, ALA31Y, ALA40Y, ARG42Y, ARG43Y, ASN45Y, ASP32Z, GLN31Z, GLY22Z, GLY29Y, GLY32Y, GLY44Y, ILE14Z, ILE21Z, ILE28Y, ILE30Y, ILE35Y, ILE36Y, LEU38Y, LEU39Y, LEU46Y, MET19Z, MET24Y, MET27Y, MET34Y, PHE17Z, PHE37Y, PRO24Z, PRO30Z, PRO33Y, SER29Z, SER36Z, TRP33Z, TYR27Z, VAL13Z, VAL18Z, VAL20Z, VAL23Z, VAL25Z
• a-b: ALA233a, ALA250a, ALA251a, ARG225a, ARG257a, ARG334a, ARG384b, ARG472b, ARG476b, ARG7b, ASN14b, ASN234a, ASN247a, ASN266a, ASP477b, ASP483b, GLN261a, GLN490b, GLU226a, GLU229a, GLU231a, GLU485b, GLU489b, GLU492b, GLY236a, GLY253a, GLY256a, GLY2b, GLY481b, GLY494b, GLY500b, HIS252a, HIS337a, ILE13b, ILE224a, ILE248a, ILE259a, ILE482b, LEU223a, LEU258a, LEU3b, LEU486b, LYS498b, MET331a, PHE255a, PHE260a, PHE383b, PHE475b, PHE479b, PHE495b, PRO340a, PRO484b, PRO488b, PRO4b, SER221a, SER222a, SER232a, SER264a, SER480b, SER487b, THR10b, THR220a, THR227a, THR228a, THR230a, THR245a, TRP468b, TRP493b, TRP5b, TYR235a, TYR246a, TYR254a, TYR262a, TYR496b, TYR6b, VAL11b, VAL219a, VAL249a, VAL330a, VAL478b, VAL491b, VAL499b
• a-c: ALA146a, ALA149a, ALA152a, ALA156a, ALA188a, ALA276a, ALA277a, ALA287a, ALA294a, ALA309c, ALA312c, ALA314c, ALA324a, ALA331c, ALA336a, ALA344a, ALA399c, ALA411c, ALA427c, ALA434c, ALA445c, ALA448c, ALA450c, ALA451c, ALA452c, ALA453c, ALA88a, ARG136a, ARG140a, ARG269a, ARG27a, ARG320c, ARG323a, ARG334a, ARG343c, ARG357c, ARG423c, ARG447c, ARG449c, ARG461c, ARG64a, ASN108a, ASN191a, ASN26a, ASN296a, ASN298a, ASN301a, ASN303a, ASN315a, ASN322a, ASN325a, ASN335a, ASN338a, ASN405c, ASN415c, ASN87a, ASP170a, ASP25a, ASP319a, ASP321c, ASP342a, ASP360c, ASP460c, ASP473c, ASP59a, ASP61a, CYS144a, CYS288c, GLN113a, GLN165a, GLN187a, GLN311c, GLN313c, GLN332c, GLU104a, GLU132a, GLU189a, GLU221c, GLU242a, GLU243a, GLU269c, GLU308c, GLU329a, GLU333a, GLU354c, GLU413c, GLU456c, GLU464c, GLU65a, GLU98a, GLY128a, GLY138a, GLY164a, GLY166a, GLY171a, GLY219c, GLY220c, GLY222c, GLY240a, GLY289a, GLY299a, GLY306c, GLY327a, GLY333c, GLY336c, GLY338c, GLY352c, GLY353c, GLY402c, GLY408c, GLY409c, GLY440c, GLY446c, GLY454c, GLY458c, GLY62a, GLY90a, HIS190a, HIS195a, HIS304a, HIS332a, HIS337a, HIS398c, HIS430c, HIS441c, HIS444c, HIS92a, ILE116a, ILE143a, ILE160a, ILE163a, ILE192a, ILE265c, ILE290a, ILE307a, ILE321a, ILE350c, ILE414c, ILE459c, ILE60a, ILE63a, ILE89a, LEU120a, LEU133a, LEU137a, LEU151a, LEU159a, LEU200a, LEU288a, LEU28a, LEU297a, LEU318c, LEU326a, LEU337c, LEU341a, LEU341c, LEU343a, LEU401c, LEU404c, LEU426c, LEU433c, LEU438c, LEU442c, LEU467c, LEU472c, LEU91a, LYS339c, LYS457c, MET127a, MET139a, MET194a, MET293a, MET315c, MET328a, MET342c, MET356c, MET396c, MET469c, PHE117a, PHE155a, PHE168a, PHE186a, PHE197a, PHE218c, PHE239a, PHE273a, PHE284c, PHE285a, PHE292c, PHE295a, PHE300a, PHE302a, PHE317c, PHE339a, PHE33a, PHE33c, PHE351c, PHE358c, PHE361c, PHE419c, PHE431c, PHE435c, PHE436c, PHE437c, PHE455c, PHE93a, PRO141a, PRO150a, PRO162a, PRO196a, PRO217c, PRO304c, PRO307c, PRO334c, PRO340a, PRO345c, PRO400c, PRO465c, PRO470c, PRO95a, SER124a, SER134a, SER148a, SER153a, SER167a, SER169a, SER216c, SER23a, SER291a, SER305a, SER310c, SER344c, SER403c, SER406c, SER416c, SER421c, SER424c, SER429c, SER463c, SER468c, SER471c, SER86a, THR24a, THR287c, THR292a, THR305c, THR316c, THR335c, THR346c, THR355c, THR397c, THR412c, THR428c, TRP131a, TRP142a, TRP284a, TRP291c, TRP32a, TRP359c, TRP36c, TRP425c, TRP443c, TYR135a, TYR147a, TYR161a, TYR29a, TYR340c, TYR395c, TYR94a, VAL145a, VAL185a, VAL280a, VAL281a, VAL283a, VAL290c, VAL306a, VAL313a, VAL328c, VAL330a, VAL407c, VAL410c, VAL417c, VAL420c, VAL432c, VAL439c, VAL466c
• a-d: ALA133d, ALA143d, ALA145d, ALA146a, ALA148d, ALA149a, ALA170d, ALA176d, ALA177d, ALA188a, ALA203a, ALA208d, ALA209a, ALA212d, ALA213a, ALA216d, ALA229d, ALA233a, ALA234d, ALA240d, ALA249d, ALA250a, ALA251a, ALA260d, ALA263a, ALA276a, ALA277a, ALA318a, ALA324a, ALA327d, ALA330d, ALA336a, ALA351d, ALA64d, ALA77d, ALA81a, ARG128d, ARG129a, ARG134d, ARG136a, ARG139d, ARG140a, ARG180d, ARG225a, ARG233d, ARG24d, ARG251d, ARG257a, ARG265d, ARG269a, ARG26d, ARG27a, ARG304d, ARG323a, ARG326d, ARG334a, ARG348d, ARG64a, ASN142d, ASN181a, ASN190d, ASN191a, ASN194d, ASN220d, ASN234a, ASN236d, ASN247a, ASN250d, ASN263d, ASN266a, ASN267a, ASN26a, ASN301a, ASN303a, ASN312a, ASN315a, ASN318d, ASN322a, ASN322d, ASN325a, ASN335a, ASN338a, ASN350d, ASN72d, ASN75a, ASN76a, ASP225d, ASP25a, ASP25d, ASP297d, ASP308a, ASP319a, ASP333d, ASP342a, ASP61a, CYS125a, CYS144a, CYS211d, CYS212a, CYS71d, GLN129d, GLN130a, GLN186d, GLN187a, GLN199a, GLN224d, GLN239d, GLN241a, GLN255d, GLN261a, GLN301d, GLN332d, GLN334d, GLU131d, GLU132a, GLU189a, GLU219d, GLU226a, GLU229a, GLU231a, GLU241d, GLU242a, GLU242d, GLU243a, GLU244a, GLU310d, GLU312d, GLU323d, GLU329a, GLU333a, GLU65a, GLU69d, GLY124d, GLY128a, GLY137d, GLY138a, GLY171a, GLY174d, GLY175a, GLY178a, GLY187d, GLY200d, GLY201a, GLY203d, GLY204a, GLY206d, GLY207a, GLY207d, GLY208a, GLY215d, GLY216a, GLY226d, GLY228d, GLY236a, GLY240a, GLY253a, GLY256a, GLY258d, GLY278d, GLY299a, GLY324d, GLY327a, GLY349d, GLY62d, GLY69a, GLY70d, GLY74a, GLY80a, HIS195a, HIS197d, HIS198a, HIS214d, HIS215a, HIS252a, HIS268d, HIS272a, HIS304a, HIS332a, HIS337a, HIS61d, ILE132d, ILE143a, ILE144d, ILE176a, ILE178d, ILE184a, ILE192a, ILE213d, ILE224a, ILE248a, ILE256d, ILE259a, ILE259d, ILE299d, ILE307a, ILE314a, ILE320a, ILE321a, ILE325d, ILE60a, ILE63a, ILE77a, ILE78a, LEU127d, LEU133a, LEU135d, LEU137a, LEU174a, LEU182d, LEU183d, LEU193a, LEU193d, LEU205d, LEU209d, LEU210a, LEU210d, LEU218a, LEU222d, LEU223a, LEU258a, LEU267d, LEU271a, LEU272d, LEU275a, LEU279d, LEU28a, LEU319d, LEU320d, LEU321d, LEU326a, LEU341a, LEU343a, LEU346d, LEU352d, LEU37d, LEU63d, LEU68d, LEU71a, LEU72a, LEU74d, LYS238a, LYS23d, LYS264d, LYS317d, MET126d, MET127a, MET139a, MET172a, MET183a, MET194a, MET198d, MET214a, MET246d, MET271d, MET328a, MET329d, MET331a, MET37a, PHE125d, PHE130d, PHE146d, PHE168d, PHE169d, PHE173d, PHE179d, PHE180a, PHE181d, PHE182a, PHE184d, PHE186a, PHE188d, PHE206a, PHE211a, PHE223d, PHE232d, PHE235d, PHE239a, PHE252d, PHE255a, PHE257d, PHE260a, PHE261d, PHE265a, PHE269d, PHE270d, PHE273a, PHE273d, PHE274a, PHE27d, PHE298d, PHE29d, PHE300a, PHE302a, PHE311d, PHE314d, PHE339a, PHE341d, PHE38d, PHE73d, PRO140d, PRO141a, PRO149d, PRO150a, PRO171d, PRO173a, PRO195d, PRO196a, PRO237d, PRO275d, PRO279a, PRO309d, PRO331d, PRO335d, PRO340a, PRO347d, PRO57a, PRO66a, PRO84a, SER134a, SER169a, SER172d, SER177a, SER217a, SER221a, SER222a, SER230d, SER232a, SER23a, SER245d, SER254d, SER262d, SER268a, SER270a, SER295d, SER300d, SER305a, SER33d, SER57d, SER65d, SER66d, SER68a, SER70a, SER79d, THR179a, THR192d, THR217d, THR220a, THR221d, THR227a, THR22a, THR231d, THR238d, THR243d, THR245a, THR248d, THR24a, THR277d, THR313d, THR316a, THR316d, THR52d, THR56d, THR60d, THR75d, THR79a, THR80d, TRP111d, TRP131a, TRP142a, TRP191d, TRP253d, TRP266d, TRP278a, TRP317a, TRP328d, TRP58d, TYR112a, TYR126a, TYR135a, TYR141d, TYR147a, TYR235a, TYR237a, TYR244d, TYR246a, TYR254a, TYR262a, TYR29a, TYR315d, TYR73a, VAL136d, VAL138d, VAL145a, VAL152d, VAL175d, VAL185a, VAL201d, VAL202a, VAL204d, VAL205a, VAL218d, VAL219a, VAL247d, VAL249a, VAL274d, VAL276d, VAL280a, VAL281a, VAL283a, VAL28d, VAL306a, VAL30a, VAL30d, VAL313a, VAL330a, VAL58a, VAL67a, VAL76d, VAL78d, VAL82a, VAL83a
• a-e: ALA309a, ALA57e, ARG257a, ARG51e, ARG61e, ARG8e, ASN312a, ASN315a, ASP308a, ASP53e, GLN261a, GLN58e, GLN60e, GLU59e, GLU7e, GLY256a, GLY311a, GLY6e, ILE307a, ILE314a, ILE63e, LYS310a, PHE10e, PHE260a, PRO50e, PRO52e, PRO64e, PRO9e, SER54e, THR4e, THR5e, TYR262a, TYR55e, TYR56e, VAL306a, VAL313a
• a-f: ALA309a, ARG19f, ARG45f, ASN312a, ASP308a, GLN44f, GLY311a, ILE307a, ILE314a, LYS310a, PHE260a, SER305a, TYR262a, VAL306a
• a-i: ALA100a, ALA29i, ALA43a, ALA99a, ARG129a, ARG136a, ARG16a, ARG30i, ARG34i, ASN12a, ASN19a, ASN31i, ASP103a, ASP27i, CYS125a, CYS18a, GLU104a, GLU132a, GLU15a, GLU2i, GLU98a, GLY128a, GLY138a, GLY22i, GLY26i, GLY31a, GLY34a, HIS118a, ILE36a, ILE38a, ILE6i, ILE96a, LEU102a, LEU114a, LEU121a, LEU133a, LEU137a, LEU17i, LEU18i, LEU24i, LEU37i, LEU4i, LYS33i, LYS35i, LYS5i, MET139a, MET1i, MET37a, PHE14i, PHE15i, PHE17a, PHE19i, PHE21i, PHE23i, PHE33a, PHE93a, PRO28i, PRO32i, PRO39a, PRO95a, SER101a, SER134a, SER23a, SER25i, THR13i, THR22a, THR24a, THR3i, THR40a, THR7i, TRP105a, TRP131a, TRP14a, TRP20a, TRP32a, TRP97a, TYR135a, TYR29a, TYR9i, VAL11i, VAL12i, VAL16i, VAL20i, VAL21a, VAL35a, VAL8i
• a-j: ALA309a, ALA32j, ASN301a, ASN303a, ASP308a, GLY311a, GLY35j, GLY37j, HIS304a, ILE307a, ILE314a, LEU36j, LEU40j, PHE29j, PHE300a, PHE302a, SER305a, SER38j, SER39j, THR316a, TYR33j, VAL306a, VAL313a
• a-l: ALA28l, ARG14l, ARG7l, ASN13l, ASN234a, ASN37l, ASN6l, ASN75a, ASN76a, GLN8l, GLU11l, GLU229a, GLU231a, GLY80a, ILE176a, ILE77a, ILE78a, LEU12l, LEU29l, LEU30l, LEU71a, PHE180a, PHE31l, PHE35l, PHE36l, PHE52a, PRO9l, SER16l, SER177a, SER232a, SER32l, SER33l, THR228a, THR230a, THR79a, TYR235a, TYR34l, VAL10l, VAL26l
• a-m: ASN75a, ASN76a, GLY74a, LEU71a, LEU72a, MET1m, THR29m, THR79a, TYR235a, TYR73a, VAL3m
• a-o: ALA100a, ALA111o, ALA336a, ALA55a, ALA88a, ALA99a, ARG115o, ARG152o, ARG162o, ARG334a, ARG64a, ARG73o, ASN108a, ASN155o, ASN335a, ASN338a, ASP103a, ASP158o, ASP59a, GLN104o, GLN109o, GLN113a, GLU104a, GLU114o, GLU333a, GLU65a, GLU74o, GLU98a, GLY109a, GLY112o, GLY113o, GLY12o, GLY161o, GLY167o, GLY62a, GLY90a, HIS92a, ILE116o, ILE172o, ILE63a, ILE89a, LEU102a, LEU106a, LEU118o, LEU119o, LEU157o, LEU70o, LYS160o, LYS69o, MET110o, MET225o, MET331a, PHE120o, PHE156o, PHE93a, PRO105o, PRO117o, PRO159o, PRO56a, PRO57a, PRO66a, PRO95a, SER101a, SER166o, SER68a, SER85a, SER86a, THR107o, THR72o, THR75o, THR76o, TRP105a, TYR107a, TYR151o, TYR168o, TYR73a, TYR94a, VAL106o, VAL108o, VAL11o, VAL330a, VAL58a, VAL67a, VAL71o
• a-t: ALA11t, ALA20t, ALA54a, ARG24t, ARG27a, ARG28t, ASN26a, ASN75a, ASN76a, GLN241a, GLU242a, GLU25t, GLU2t, GLY240a, GLY74a, ILE14t, ILE21t, ILE29t, ILE46a, ILE4t, ILE53a, ILE77a, ILE78a, ILE9t, LEU28a, LEU71a, LEU72a, LYS238a, MET1t, PHE10t, PHE17t, PHE18t, PHE19t, PHE22t, PHE239a, PHE23t, PHE48a, PHE52a, PHE8t, PRO26t, PRO27t, SER70a, THR30t, THR3t, THR45a, THR5t, THR79a, TYR235a, TYR237a, TYR6t, TYR73a, VAL49a, VAL7t
• a-u: ASN338a, ASN99u, GLY101u, HIS337a, LEU102u, LEU341a, LYS104u, PHE339a, PRO340a, TYR103u, VAL330a
• a-v: ALA1v, ALA309a, ARG323a, ASN303a, ASN312a, ASN315a, ASN322a, ASN49v, ASP308a, ASP319a, ASP342a, CYS40v, GLU122v, GLU23v, GLU2v, GLU329a, GLU6v, GLY127v, GLY133v, GLY311a, GLY327a, GLY43v, HIS304a, HIS332a, ILE125v, ILE307a, ILE314a, ILE320a, ILE45v, LEU126v, LEU326a, LEU341a, LEU343a, LEU3v, LEU8v, LYS124v, LYS129v, LYS134v, LYS30v, LYS310a, LYS47v, PHE339a, PRO123v, PRO340a, PRO50v, SER39v, THR46v, THR48v, THR4v, TYR136v, TYR137v, TYR26v, VAL121v, VAL135v, VAL313a, VAL330a, VAL42v, VAL7v
• b-d: ALA133d, ALA143d, ALA145d, ALA148d, ALA151d, ALA170d, ALA228b, ALA253b, ALA283d, ALA290d, ALA306d, ALA320b, ALA327d, ALA330d, ALA351d, ALA361b, ALA379b, ALA386b, ALA454b, ALA456b, ALA459b, ALA471b, ARG128d, ARG12d, ARG134d, ARG139d, ARG180d, ARG224b, ARG230b, ARG24d, ARG265d, ARG26d, ARG272b, ARG294d, ARG326b, ARG326d, ARG348d, ARG357b, ARG358b, ARG384b, ARG385b, ARG444b, ARG448b, ARG472b, ARG476b, ARG7b, ASN190d, ASN194d, ASN292d, ASN318b, ASN322d, ASN338d, ASN350d, ASN438b, ASN83d, ASP16d, ASP19d, ASP20d, ASP25d, ASP276b, ASP297d, ASP333d, ASP380b, ASP440b, ASP477b, ASP483b, ASP501b, GLN129d, GLN164d, GLN334d, GLN394b, GLN395b, GLN490b, GLN497b, GLU131d, GLU302d, GLU323d, GLU337d, GLU343d, GLU344d, GLU364b, GLU387b, GLU489b, GLU492b, GLY137d, GLY13d, GLY163d, GLY187d, GLY254b, GLY285d, GLY288d, GLY31d, GLY322b, GLY323b, GLY333b, GLY349d, GLY375b, GLY441b, GLY449b, GLY465b, GLY470b, GLY481b, GLY494b, GLY500b, GLY86d, HIS189d, HIS197d, HIS336d, HIS455b, HIS466b, HIS469b, HIS87d, ILE123d, ILE132d, ILE144d, ILE150d, ILE159d, ILE17d, ILE284d, ILE299d, ILE303d, ILE315b, ILE325d, ILE369b, ILE381b, ILE442b, ILE467b, ILE482b, LEU122d, LEU127d, LEU135d, LEU158d, LEU162d, LEU18d, LEU193d, LEU22d, LEU272d, LEU279d, LEU289d, LEU291d, LEU293d, LEU319d, LEU320d, LEU324b, LEU346d, LEU352d, LEU370b, LEU460b, LEU461b, LEU474b, LEU486b, LYS23d, LYS321b, LYS332b, LYS378b, LYS389b, LYS498b, MET126d, MET199d, MET281d, MET329d, MET359b, PHE130d, PHE146d, PHE153d, PHE15d, PHE168d, PHE169d, PHE181d, PHE184d, PHE185d, PHE188d, PHE196d, PHE250b, PHE269d, PHE273d, PHE27d, PHE298d, PHE29d, PHE325b, PHE339d, PHE341d, PHE362b, PHE363b, PHE366b, PHE383b, PHE392b, PHE443b, PHE451b, PHE453b, PHE458b, PHE462b, PHE463b, PHE464b, PHE475b, PHE479b, PHE495b, PRO140d, PRO149d, PRO161d, PRO195d, PRO237d, PRO319b, PRO331d, PRO342d, PRO347d, PRO360b, PRO367b, PRO382b, PRO488b, SER147d, SER155d, SER165d, SER166d, SER282d, SER295d, SER300d, SER365b, SER388b, SER391b, SER439b, SER446b, SER480b, SER487b, THR238d, THR277d, THR327b, THR371b, THR445b, THR452b, THR473b, THR504b, TRP167d, TRP191d, TRP21d, TRP257b, TRP266d, TRP280d, TRP328d, TRP32d, TRP450b, TRP468b, TRP493b, TRP5b, TYR141d, TYR160d, TYR258b, TYR273b, TYR296d, TYR315d, TYR390b, TYR496b, TYR6b, VAL136d, VAL138d, VAL152d, VAL154d, VAL156d, VAL276d, VAL286d, VAL287d, VAL30d, VAL340d, VAL345d, VAL368b, VAL376b, VAL377b, VAL457b, VAL478b, VAL491b, VAL499b
• b-e: GLN497b, GLU492b, GLY494b, GLY6e, PHE495b, THR4e, THR5e, TRP493b, TYR496b, VAL499b
• b-h: ALA132b, ALA182b, ALA205b, ALA228b, ALA22h, ALA261b, ALA2h, ALA32h, ALA64h, ARG124b, ARG127b, ARG12h, ARG220b, ARG224b, ARG286b, ARG3h, ARG448b, ARG476b, ARG4h, ASN14b, ASN15h, ASN191b, ASN194b, ASN233b, ASN50h, ASN59h, ASP119b, ASP125b, ASP134b, ASP170b, ASP188b, ASP56h, ASP9h, GLN223b, GLN274b, GLN282b, GLU121b, GLU130b, GLU17h, GLU184b, GLU266b, GLU283b, GLY129b, GLY173b, GLY186b, GLY189b, GLY196b, GLY197b, GLY19h, GLY232b, GLY24h, GLY254b, GLY259b, GLY269b, GLY26h, GLY57h, GLY66h, GLY8h, HIS114b, HIS201b, HIS216b, ILE10h, ILE141b, ILE211b, ILE217b, ILE234b, ILE265b, ILE44h, ILE45h, ILE48h, LEU11h, LEU120b, LEU122b, LEU133b, LEU135b, LEU145b, LEU14h, LEU218b, LEU225b, LEU229b, LEU30h, LEU42h, LEU46h, LEU53h, LEU55h, LEU65h, LEU7h, LYS137b, LYS20h, LYS227b, LYS63h, MET138b, MET231b, MET256b, MET31h, MET35h, PHE123b, PHE190b, PHE215b, PHE247b, PHE268b, PHE280b, PHE34h, PHE38h, PHE41h, PRO126b, PRO131b, PRO136b, PRO13h, PRO16b, PRO171b, PRO187b, PRO192b, PRO195b, PRO221b, PRO222b, PRO23h, PRO264b, PRO270b, PRO29h, SER169b, SER16h, SER260b, SER277b, SER51h, SER61h, THR128b, THR175b, THR255b, THR262b, THR263b, THR271b, THR27h, THR28h, THR5h, TRP113b, TRP118b, TRP167b, TRP257b, TRP25h, TRP62h, TYR117b, TYR172b, TYR18h, TYR193b, TYR226b, TYR258b, TYR273b, TYR279b, TYR49h, VAL116b, VAL168b, VAL181b, VAL208b, VAL219b, VAL21h, VAL251b, VAL58h, VAL60h
• b-l: ARG124b, ARG18b, ARG326b, ARG444b, ARG7b, ARG7l, ASN13l, ASN14b, ASN37l, ASN4l, ASN6l, ASP119b, ASP15b, ASP440b, GLN8l, GLU11l, GLU2l, GLY17b, GLY20l, GLY2b, GLY323b, HIS114b, HIS9b, ILE13b, ILE442b, LEU12b, LEU12l, LEU19b, LEU23l, LEU30l, LEU324b, LEU3b, MET1l, PHE31l, PHE325b, PHE35l, PHE36l, PRO131b, PRO16b, PRO3l, PRO4b, PRO5l, PRO9l, SER16l, SER33l, THR10b, THR327b, TRP115b, TRP118b, TRP5b, TYR117b, TYR34l, TYR6b, VAL10l, VAL116b, VAL11b, VAL8b
• b-m: ARG326b, ARG444b, ARG7b, ASN438b, ASN4m, ASP440b, GLN28m, GLN32m, GLN5m, GLU2m, GLY2b, GLY328b, HIS9b, LEU22m, LEU25m, LEU3b, LEU6m, LYS332b, PHE21m, PHE325b, PRO4b, THR29m, THR327b, TRP5b, TYR40b, TYR6b, VAL3m, VAL8b
• b-o: ALA154o, ALA165o, ALA171o, ALA173o, ALA177o, ALA386b, ARG162o, ARG326b, ARG384b, ARG385b, ARG422b, ARG57b, ASN155o, ASN186o, ASP169o, ASP334b, ASP433b, ASP440b, GLN176o, GLN338b, GLU179o, GLU180o, GLU181o, GLU364b, GLU387b, GLU428b, GLU431b, GLU435b, GLY161o, GLY163o, GLY167o, GLY316b, GLY333b, GLY335b, GLY441b, ILE172o, ILE315b, ILE336b, ILE381b, ILE425b, ILE429b, ILE442b, LEU157o, LEU164o, LEU174o, LEU182o, LYS160o, LYS178o, LYS188o, LYS321b, LYS341b, LYS418b, LYS423b, MET359b, PHE311b, PHE363b, PHE366b, PHE383b, PHE426b, PHE430b, PHE432b, PHE443b, PRO175o, PRO367b, PRO382b, PRO415b, SER166o, SER170o, SER365b, SER419b, SER439b, THR416b, THR434b, THR436b, TYR168o, TYR314b, TYR420b, VAL187o, VAL368b
• b-u: ALA20u, ALA33u, ALA34u, ALA386b, ARG384b, ARG385b, ARG422b, ASN100u, ASN11u, ASN31u, ASP14u, ASP96u, GLN37u, GLN394b, GLN395b, GLU15u, GLU23u, GLU387b, GLU393b, GLU8u, GLY101u, GLY18u, GLY22u, GLY396b, ILE381b, LEU102u, LEU17u, LEU91u, LEU9u, LYS104u, LYS16u, LYS24u, LYS349b, LYS389b, LYS418b, PHE383b, PHE392b, PRO382b, PRO414b, PRO415b, SER388b, SER391b, THR19u, THR30u, TYR103u, TYR21u, TYR390b, VAL10u, VAL12u, VAL13u
• b-v: ARG384b, ARG55v, GLU387b, LYS134v, LYS389b, SER51v, TYR136v, VAL135v
• b-x: ARG39x, ARG505b, ASP501b, GLN38x, GLN497b, LYS36x, LYS498b, PRO187b, SER40x, THR2x, THR503b, THR504b, TYR496b, VAL37x, VAL499b, VAL502b
• c-d: ALA229d, ALA234d, ALA240d, ALA249d, ALA260d, ALA34c, ALA351d, ALA37c, ALA40c, ALA451c, ARG233d, ARG251d, ARG41c, ARG447c, ARG461c, ASN220d, ASN236d, ASN250d, ASN350d, ASN405c, ASN72d, ASP225d, ASP27c, ASP460c, ASP473c, GLN224d, GLN239d, GLN255d, GLN28c, GLN313c, GLU219d, GLU227d, GLU241d, GLU242d, GLU29c, GLU354c, GLU456c, GLU462c, GLU464c, GLY226d, GLY228d, GLY258d, GLY32c, GLY333c, GLY454c, GLY458c, ILE256d, ILE459c, LEU222d, LEU352d, LEU404c, LEU467c, LEU472c, LEU74d, LYS339c, LYS457c, MET246d, MET469c, PHE223d, PHE22c, PHE232d, PHE235d, PHE252d, PHE33c, PHE455c, PRO334c, PRO465c, PRO470c, SER230d, SER245d, SER254d, SER31c, SER463c, SER468c, SER471c, THR221d, THR231d, THR243d, THR248d, THR335c, THR412c, TRP253d, TRP328d, TRP35c, TRP36c, TRP443c, TYR244d, VAL218d, VAL247d, VAL410c, VAL466c
• c-i: ALA260c, ALA263c, ALA29i, ALA448c, ALA450c, ALA451c, ALA452c, ALA453c, ARG261c, ARG262c, ARG30i, ARG34i, ARG449c, ARG461c, ASN31i, ASP27i, ASP36i, ASP460c, GLU38i, GLU462c, GLU464c, GLY258c, GLY26i, GLY454c, GLY458c, ILE265c, ILE459c, LEU24i, LEU37i, LYS152c, LYS154c, LYS33i, LYS35i, MET469c, PHE23i, PHE257c, PHE264c, PHE455c, PRO28i, PRO32i, PRO465c, SER25i, SER267c, SER463c, SER468c, TRP259c, TRP266c, TYR274c, VAL466c
• c-j: ALA32j, ASN405c, ASN415c, ASN418c, GLY37j, ILE414c, LEU404c, LEU40j, PHE29j, SER38j, SER39j, SER406c, SER416c, TYR33j, VAL407c, VAL417c
• c-k: ALA14k, ALA16k, ALA23c, ALA34c, ALA36k, ALA37c, ALA42k, ALA55c, ALA64c, ALA66c, ALA73c, ARG26c, ARG41c, ARG46k, ASN25c, ASN39c, ASP107c, ASP19k, ASP23k, ASP27c, GLN28c, GLN40k, GLN84c, GLU29c, GLU71c, GLU78c, GLY115c, GLY126c, GLY38c, GLY44k, GLY58c, GLY65c, HIS56c, HIS74c, ILE134c, ILE21c, ILE28k, ILE60c, ILE76c, ILE89c, LEU119c, LEU11k, LEU21k, LEU25k, LEU31k, LEU33k, LEU42c, LEU59c, LEU69c, LEU72c, LYS10k, LYS48c, MET67c, PHE109c, PHE111c, PHE112c, PHE18k, PHE22c, PHE32k, PHE33c, PHE37k, PHE45k, PHE62c, PHE70c, PHE75c, PRO12k, PRO20k, PRO26k, PRO29k, PRO77c, SER122c, SER20c, SER30c, SER31c, THR108c, THR24c, THR68c, TRP35c, TRP36c, TRP39k, TRP63c, TYR15k, VAL113c, VAL116c, VAL130c, VAL22k, VAL24k, VAL27k, VAL30k, VAL43k, VAL61c
• c-l: ARG14l, ASP473c
• c-o: ALA154o, ALA16o, ALA326c, ALA331c, ALA41o, ARG152o, ARG343c, ARG362c, ARG370c, ARG39o, ARG42o, ARG73o, ASN124o, ASN155o, ASN17o, ASN228c, ASN327c, ASN373c, ASN378c, ASN382c, ASP102o, ASP360c, ASP376c, ASP79o, ASP8o, ASP99o, ASP9o, CYS19o, CYS44o, GLN104o, GLN322c, GLN332c, GLN46o, GLN80o, GLN82o, GLU221c, GLU348c, GLU367c, GLU74o, GLU97o, GLU98o, GLY100o, GLY12o, GLY14o, GLY220c, GLY329c, GLY333c, GLY336c, GLY338c, GLY347c, GLY371c, GLY374c, ILE101o, ILE10o, ILE349c, ILE350c, ILE380c, ILE81o, LEU118o, LEU119o, LEU157o, LEU15o, LEU337c, LEU341c, LEU375c, LEU377c, LEU45o, LEU5o, LEU78o, LYS123o, LYS18o, LYS339c, LYS379c, LYS381c, MET225o, MET342c, PHE103o, PHE120o, PHE156o, PHE190o, PHE361c, PRO105o, PRO149o, PRO20o, PRO334c, PRO345c, PRO372c, PRO47o, SER150o, SER330c, SER344c, SER77o, THR121o, THR13o, THR153o, THR335c, THR346c, THR4o, THR6o, THR72o, THR75o, THR76o, TRP359c, TYR151o, TYR340c, TYR7o, VAL106o, VAL11o, VAL148o, VAL328c
• c-t: ARG24t, ARG28t, ASP473c, GLU25t, ILE21t, ILE29t, LEU467c, LEU472c, MET469c, PHE22t, PHE23t, PRO26t, PRO27t, PRO470c, SER471c, VAL466c
• c-u: ALA326c, ALA331c, ALA33u, ALA46u, ARG320c, ARG97u, ASN100u, ASN31u, ASN327c, ASN99u, ASP321c, ASP96u, GLN313c, GLN322c, GLN332c, GLU93u, GLY101u, GLY325c, GLY333c, GLY338c, GLY94u, GLY95u, ILE32u, ILE36u, LEU102u, LEU318c, LEU324c, LEU48u, LYS104u, LYS323c, LYS339c, LYS47u, LYS51u, PHE317c, PHE35u, PRO334c, PRO43u, SER330c, THR44u, TYR103u, TYR340c, TYR42u, TYR98u, VAL328c, VAL50u
• c-v: ALA312c, ALA36v, ALA38v, ALA392c, ALA393c, ALA399c, ALA411c, ALA89v, ALA98v, ARG105v, ARG31v, ARG320c, ARG390c, ARG391c, ASN106v, ASN415c, ASN418c, ASN49v, ASP321c, ASP99v, CYS37v, CYS40v, GLN313c, GLN34v, GLN385c, GLN388c, GLN84c, GLN86v, GLU104c, GLU122v, GLU389c, GLU394c, GLU413c, GLU78c, GLU83c, GLU90v, GLY131v, GLY133v, GLY408c, GLY409c, GLY43v, GLY44v, HIS118v, HIS398c, HIS41v, HIS92v, ILE100v, ILE319c, ILE384c, ILE414c, ILE45v, ILE76c, ILE88v, LEU126v, LEU324c, LEU52v, LYS103v, LYS129v, LYS134v, LYS30v, LYS323c, LYS47v, LYS79c, MET104v, MET396c, PHE101v, PHE317c, PHE33v, PHE419c, PRO102v, PRO386c, PRO50v, PRO77c, PRO80c, PRO93v, SER39v, SER416c, SER51v, SER97v, THR316c, THR397c, THR412c, THR46v, THR48v, THR81v, TRP130v, TRP387c, TYR136v, TYR137v, TYR35v, TYR395c, TYR82c, VAL105c, VAL407c, VAL410c, VAL417c, VAL42v, VAL91v
• c-y: ALA133c, ARG135c, ARG26c, ARG43y, ASN19c, ASN45y, GLN21y, GLU138c, GLY44y, HIS74c, ILE134c, ILE28y, ILE35y, LEU39y, LEU46y, LYS48c, PHE62c, PHE70c, THR24c, VAL130c
• c-z: ALA123c, ALA133c, ALA26z, ALA28z, ARG135c, ARG26c, ASN58z, ASP32z, ASP34z, GLN31z, GLY126c, GLY128c, GLY129c, GLY136c, GLY43z, GLY55z, HIS132c, ILE120c, ILE134c, ILE40z, ILE48z, LEU119c, LEU125c, LEU12z, LEU52z, LEU9z, LYS37z, MET19z, PHE109c, PHE112c, PHE127c, PHE41z, PHE59z, PHE5z, PHE62c, PRO24z, PRO30z, SER121c, SER122c, SER16z, SER29z, SER36z, SER44z, TRP33z, TRP47z, TYR131c, TYR27z, VAL113c, VAL116c, VAL117c, VAL124c, VAL130c, VAL13z, VAL20z, VAL23z, VAL25z, VAL51z, VAL54z, VAL62z
• d-e: ALA43e, ALA57e, ALA64d, ALA72e, ALA82d, ALA97d, ARG103d, ARG24d, ARG26d, ARG51e, ARG61e, ARG69e, ARG8e, ASN338d, ASN83d, ASP100d, ASP25d, ASP45e, ASP68e, CYS105d, GLN106d, GLN332d, GLN334d, GLN60e, GLN74e, GLN75e, GLN98d, GLU337d, GLU69d, GLU71e, GLU77e, GLU7e, GLU81e, GLU96d, GLY108d, GLY34e, GLY41e, GLY47d, GLY48e, GLY51d, GLY62d, GLY6e, GLY70d, GLY86d, GLY94d, GLY99d, HIS336d, HIS61d, HIS87d, ILE63e, LEU107d, LEU110d, LEU42e, LEU63d, LEU65e, LEU68d, LEU80e, LEU83e, LEU89d, LEU90d, LEU91d, LYS73e, MET85d, PHE101d, PHE10e, PHE168d, PHE27d, PHE29d, PHE37e, PHE47e, PHE54d, PHE70e, PHE79e, PRO335d, PRO50e, PRO52e, PRO64e, PRO81d, PRO95d, PRO9e, SER166d, SER39e, SER54e, SER57d, SER62e, SER65d, SER66d, SER84d, SER88d, THR102d, THR49e, THR4e, THR50d, THR53d, THR56d, THR5e, THR60d, THR67e, THR78e, TRP104d, TRP167d, TRP58d, TYR44e, TYR55e, TYR56e, TYR59d, TYR67d, VAL28d, VAL38e, VAL46e, VAL55d, VAL66e, VAL76e
• d-f: ALA22f, ALA27f, ALA36f, ALA38f, ALA39f, ALA41d, ARG19f, ARG24d, ARG26d, ARG45f, ASN72d, CYS71d, GLN41f, GLU69d, GLY31d, GLY35f, GLY46d, GLY47d, GLY51d, GLY70d, HIS24f, ILE37f, ILE43f, LEU22d, LEU26f, LEU34f, LEU45d, LEU49d, LEU68d, MET40f, PHE16f, PHE27d, PHE29d, PHE32f, PHE33f, PHE38d, PHE54d, PRO29f, SER66d, THR17f, THR25f, THR30f, THR50d, THR52d, THR53d, TRP20f, TRP21d, TRP48d, TYR42d, TYR67d, VAL18f, VAL21f, VAL23f, VAL28d, VAL28f, VAL30d, VAL55d, VAL76d
• d-h: ARG12d, ASN50h, ASP16d, ASP19d, GLU47h, GLU96d, GLY13d, GLY86d, GLY94d, HIS87d, ILE48h, ILE54h, LEU116d, LEU162d, LEU39h, LEU43h, LEU46h, LEU53h, LEU89d, LEU90d, LEU91d, MET85d, PHE120d, PHE15d, PRO29h, PRO95d, SER51h, SER88d, THR112d, THR28h, THR52h, TRP14d, TRP167d, TRP25h, TRP32d, TRP93d, TYR49h
• d-j: ALA32j, ALA34j, ALA64d, ASN72d, CYS71d, GLU69d, GLY31j, GLY35j, GLY37j, GLY70d, LEU36j, LEU68d, PHE28j, PHE29j, PHE73d, SER38j, SER39j, SER66d, THR75d, TYR67d
• d-k: ARG233d, ARG46k, PHE45k
• d-l: ALA202d, ALA260d, ARG294d, ASN13l, ASN190d, ASN194d, ASN263d, ASN37l, ASP297d, GLN301d, GLU302d, GLY200d, HIS197d, ILE259d, ILE284d, ILE299d, ILE303d, LEU193d, LEU19l, LEU22l, LEU23l, LEU27l, LEU30l, MET198d, MET199d, MET281d, PHE196d, PHE261d, PHE269d, PHE270d, PHE273d, PHE298d, PHE31l, PHE35l, PHE36l, PRO195d, SER16l, SER262d, SER295d, SER300d, SER32l, SER33l, THR15l, THR192d, THR277d, TRP266d, TYR18l, TYR296d, TYR315d, TYR34l, VAL26l
• d-m: ALA305d, ARG304d, ASN4m, GLN301d, GLU2m, GLU302d, GLU307d, ILE299d, ILE303d, MET199d, MET1m, PHE14m, PHE298d, PHE311d, SER300d, THR313d, VAL3m
• d-o: ALA171o, ALA173o, ALA177o, ALA185o, ALA227o, ALA305d, ALA306d, ALA327d, ALA351d, ARG115o, ARG152o, ARG162o, ARG184o, ARG304d, ARG326d, ARG348d, ASN155o, ASN186o, ASN322d, ASN350d, ASP158o, ASP222o, ASP223o, ASP224o, ASP297d, ASP308d, GLN301d, GLU181o, GLU302d, GLU307d, GLU310d, GLU312d, GLU323d, GLU344d, GLY161o, GLY167o, GLY226o, GLY324d, GLY349d, HIS228o, ILE172o, ILE299d, ILE303d, LEU157o, LEU174o, LEU182o, LEU319d, LEU320d, LEU346d, LYS160o, LYS188o, LYS317d, MET225o, PHE156o, PHE298d, PHE311d, PRO117o, PRO159o, PRO175o, PRO309d, PRO347d, SER166o, SER170o, SER300d, THR153o, THR313d, THR316d, TYR151o, TYR168o, TYR296d, TYR315d, VAL345d
• d-t: ALA20t, ALA260d, ARG24t, ARG251d, ARG28t, ASN250d, ASN263d, GLN255d, GLU25t, GLU2t, GLY258d, ILE21t, ILE259d, ILE29t, LEU16t, MET246d, PHE17t, PHE19t, PHE22t, PHE23t, PHE257d, PHE261d, PHE298d, PRO26t, PRO27t, SER254d, SER262d, SER300d, THR248d, THR30t, TRP253d, TYR6t, VAL247d
• d-u: ALA351d, ARG348d, ASN100u, ASN350d, ASN99u, GLU343d, GLU344d, GLY101u, GLY349d, LEU102u, LEU17u, LEU346d, LEU352d, LYS104u, TRP328d, TYR103u
• d-v: ALA351d, ARG348d, ARG55v, ASN350d, ASP128v, GLN332d, GLU343d, GLU344d, GLY132v, GLY133v, LEU346d, LEU352d, LYS129v, LYS134v, PHE341d, PRO342d, PRO50v, TRP328d, TYR136v, TYR137v, VAL135v, VAL340d
• d-x: ALA26x, ALA30x, ARG12d, ARG24d, ARG26d, ARG39x, ASP16d, ASP19d, ASP20d, ASP25d, ASP35x, GLN33x, GLN38x, GLN98d, GLU96d, GLY13d, GLY13x, GLY17x, GLY31d, GLY34d, GLY94d, GLY99d, GLY9x, HIS117d, ILE12x, ILE17d, ILE29x, ILE31x, ILE34x, ILE35d, LEU14x, LEU18d, LEU21x, LEU22d, LEU28x, LEU36d, LEU43d, LEU7x, LEU91d, LEU92d, LYS23d, LYS36x, LYS8x, PHE10x, PHE11x, PHE15d, PHE25x, PRO39d, PRO5x, PRO95d, SER16x, SER32x, SER6x, THR24x, THR4x, TRP14d, TRP21d, TRP32d, TRP93d, VAL20x, VAL27x, VAL30d, VAL37x
• e-f: ALA22f, ALA27f, ALA29e, ALA33e, ALA36f, ALA38f, ALA39f, ALA43e, ARG19f, ARG45f, ARG51e, ARG8e, ASP12e, ASP53e, GLN41f, GLN44f, GLU7e, GLY34e, GLY35f, GLY41e, GLY6e, HIS23e, HIS24f, ILE13e, ILE14e, ILE22e, ILE27e, ILE31f, ILE32e, ILE37f, ILE43f, LEU30e, LEU34f, LEU36e, LEU42e, MET40f, PHE10e, PHE31e, PHE32f, PHE33f, PHE37e, PHE42f, PHE47e, PRO28e, PRO29f, PRO52e, PRO9e, SER11e, SER39e, THR17f, THR26e, THR30f, THR40e, THR49e, THR4e, THR5e, TRP20f, TRP35e, TYR19e, TYR44e, TYR55e, VAL18f, VAL23f, VAL28f, VAL38e, VAL46e
• e-h: ARG69e, ASN50h, GLU47h, ILE48h, ILE54h, LEU53h, PHE70e, SER51h, THR52h, TYR49h
• e-j: ALA14j, ALA17j, ARG18e, ARG51e, ARG7j, ARG8e, ASP12e, ASP53e, GLU4j, GLY5j, GLY6j, ILE12j, ILE13e, ILE14e, ILE22e, ILE24j, ILE8j, LEU10j, LEU27j, LEU36j, MET1j, MET2j, PHE10e, PHE28j, PHE31e, PRO50e, PRO52e, PRO9e, PRO9j, SER11e, SER16e, SER3j, THR15e, TRP11j, TRP20e, TRP35e, TYR19e, TYR44e, TYR55e, VAL13j, VAL16j, VAL17e, VAL21e, VAL23j
• e-v: ALA1v, ALA57e, ARG51e, ARG61e, ASP128v, ASP53e, GLN58e, GLN60e, GLU122v, GLU2v, GLU59e, GLU6v, GLY127v, ILE125v, ILE63e, LEU126v, LEU3v, LEU83e, LEU8v, LYS124v, LYS129v, LYS84e, PRO123v, PRO52e, PRO5v, SER54e, THR4v, TRP130v, TYR55e, TYR56e, VAL121v, VAL7v
• e-x: PHE70e, SER6x
• f-j: ALA32j, ALA34j, ALA36f, ALA38f, ALA39f, ARG45f, GLN41f, GLN44f, GLY20j, GLY26j, GLY31j, GLY35f, GLY35j, GLY37j, ILE24j, ILE31f, ILE37f, ILE43f, LEU27j, LEU34f, LEU36j, LEU40j, MET40f, PHE28j, PHE29j, PHE33f, PHE42f, SER38j, SER39j, TYR30j, TYR33j, VAL21j, VAL25j
• f-v: ALA1v, ARG45f, GLN44f, GLU122v, GLU23v, GLU2v, HIS118v, ILE125v, LEU27v, LEU3v, LYS30v, TYR26v
• f-y: LEU22y, PHE42f
• f-x: ASP35x, ILE15f, ILE31x, ILE34x, LEU28x, PHE16f, VAL18f, VAL21f
• h-l: ALA2h, ARG3h, GLU2l, MET1l
• h-x: ALA18x, ASP56h, GLU47h, GLY13x, GLY17x, GLY36h, GLY57h, GLY9x, ILE3x, ILE44h, ILE45h, ILE48h, ILE54h, LEU14x, LEU21x, LEU37h, LEU39h, LEU42h, LEU43h, LEU46h, LEU53h, LEU55h, LEU7x, LYS8x, PHE10x, PHE11x, PHE41h, PRO5x, SER51h, SER6x, THR2x, THR4x, THR52h, VAL40h, VAL58h
• i-o: LYS69o, MET1i
• j-k: ALA14j, ALA34k, ALA41k, ALA42k, GLN40k, GLY18j, GLY44k, ILE12j, ILE22j, LEU10j, LEU31k, LEU35k, MET19j, PHE37k, PHE45k, PRO9j, THR15j, TRP11j, TRP39k, VAL16j, VAL27k, VAL30k, VAL38k, VAL43k
• j-v: ARG31v, GLN34v, LEU27v, LEU40j, LYS30v, SER38j, SER39j, TYR26v
• j-y: ALA26y, ALA31y, ALA40y, GLY29y, GLY32y, ILE12j, ILE22j, ILE25y, ILE28y, ILE30y, ILE35y, ILE36y, ILE8j, LEU22y, LEU27j, LEU38y, LEU39y, LEU46y, MET19j, MET34y, PHE37y, PRO33y, PRO9j, THR15j, TRP11j, TYR30j, VAL16j, VAL18y, VAL23j, VAL41y
• k-v: ASN106v, LYS10k
• k-y: ALA20y, ALA26y, ALA31y, ALA34k, ALA36k, ALA40y, ALA41k, ALA42k, ARG46k, ASN45y, ASP19k, ASP23k, GLN21y, GLN40k, GLY29y, GLY32y, GLY44k, GLY44y, ILE17k, ILE19y, ILE25y, ILE28k, ILE28y, ILE30y, ILE35y, ILE36y, LEU21k, LEU22y, LEU25k, LEU31k, LEU35k, LEU39y, LEU46y, MET24y, MET27y, MET34y, PHE18k, PHE32k, PHE37k, PHE37y, PRO20k, PRO33y, THR23y, TRP39k, VAL18y, VAL22k, VAL24k, VAL27k, VAL38k, VAL43k
• k-z: ALA10z, ALA11z, ALA14k, ALA16k, ALA8z, ASN58z, GLN6z, GLU13k, GLY55z, ILE14z, ILE17k, ILE28k, ILE3z, LEU11k, LEU12z, LEU21k, LEU25k, LEU35k, LEU57z, LEU7z, LEU9z, MET1z, PHE17z, PHE18k, PHE32k, PHE59z, PHE5z, PHE60z, PRO12k, PRO24z, SER16z, THR2z, TYR15k, VAL13z, VAL20z, VAL22k, VAL54z, VAL61z, VAL62z
• l-m: ALA10m, ALA12m, ALA28l, ARG14l, ASN13l, ASN37l, ASN4m, GLN28m, GLN32m, GLN5m, GLN8l, GLU11l, GLU2m, GLU30m, GLY20l, GLY7m, ILE23m, ILE24l, ILE24m, ILE9m, LEU12l, LEU13m, LEU16m, LEU17l, LEU19l, LEU21l, LEU22l, LEU22m, LEU23l, LEU25l, LEU25m, LEU27l, LEU29l, LEU30l, LEU6m, LEU8m, MET1m, PHE14m, PHE21m, PHE31l, PHE35l, PHE36l, PRO18m, PRO9l, SER16l, SER19m, SER32l, SER33l, THR11m, THR15l, THR29m, TYR18l, TYR26m, TYR34l, VAL10l, VAL15m, VAL17m, VAL20m, VAL26l, VAL27m, VAL3m
• l-t: ALA11t, ALA15t, ALA20t, ALA28l, ARG14l, ARG24t, ASN13l, ASN37l, CYS12t, GLU25t, GLU2t, GLY20l, ILE13t, ILE14t, ILE21t, ILE24l, ILE4t, ILE9t, LEU12l, LEU16t, LEU17l, LEU19l, LEU21l, LEU22l, LEU23l, LEU25l, LEU27l, LEU29l, LEU30l, MET1t, PHE10t, PHE17t, PHE18t, PHE19t, PHE22t, PHE23t, PHE31l, PHE35l, PHE36l, PHE8t, PRO26t, SER16l, SER32l, SER33l, THR15l, THR3t, THR5t, TYR18l, TYR34l, TYR6t, VAL26l, VAL7t
• m-t: ALA10m, ALA12m, ASN4m, CYS12t, GLN5m, GLU25t, GLU2m, GLU2t, GLU30m, GLY7m, ILE4t, ILE9m, ILE9t, LEU16m, LEU16t, LEU6m, LEU8m, MET1m, MET1t, PHE14m, PHE23t, PHE8t, SER19m, THR11m, THR3t, THR5t, TYR26m, TYR6t, VAL15m, VAL3m
• o-u: ALA154o, ALA165o, ALA183o, ALA185o, ALA227o, ALA90u, ARG152o, ARG162o, ARG184o, ARG189o, ASN100u, ASN11u, ASN124o, ASN147o, ASN155o, ASN186o, ASN99u, ASP14u, ASP169o, ASP96u, ASP99o, GLU15u, GLU180o, GLU88u, GLU8u, GLU93u, GLU98o, GLY101u, GLY163o, GLY167o, GLY226o, GLY94u, GLY95u, LEU102u, LEU119o, LEU164o, LEU17u, LEU182o, LEU192o, LEU91u, LEU9u, LYS123o, LYS188o, LYS51u, MET225o, PHE103o, PHE156o, PHE190o, PRO149o, SER150o, SER166o, SER191o, THR153o, THR193o, THR89u, TYR168o, TYR21u, VAL10u, VAL12u, VAL13u, VAL148o, VAL187o, VAL87u, VAL92u
• u-v: ALA33u, ALA34u, ALA46u, ALA60v, ALA62v, ARG39u, ARG55v, ARG66v, ARG70u, ASN100u, ASN31u, ASN49v, ASN78u, ASN99u, ASP128v, ASP53v, ASP67v, ASP83v, GLN37u, GLN71u, GLN86v, GLU57v, GLU85v, GLY131v, GLY132v, GLY133v, GLY40u, GLY44v, GLY84v, ILE32u, ILE36u, ILE45v, ILE74u, ILE88v, LEU102u, LEU41u, LEU45u, LEU52v, LEU54v, LEU59v, LEU61v, LYS104u, LYS129v, LYS134v, LYS47u, LYS47v, PHE35u, PRO43u, PRO50v, PRO64v, PRO65v, SER14v, SER51v, THR44u, THR46v, THR48v, THR58v, THR63v, THR68u, THR80v, THR81v, TRP130v, TYR103u, TYR136v, TYR38u, TYR42u, TYR82v, TYR98u, VAL135v
• y-z: ALA26y, ALA26z, ALA28z, ALA31y, ALA40y, ARG42y, ARG43y, ASN45y, ASP32z, GLN31z, GLY22z, GLY29y, GLY32y, GLY44y, ILE14z, ILE21z, ILE25y, ILE28y, ILE30y, ILE35y, ILE36y, LEU38y, LEU39y, LEU46y, MET19z, MET24y, MET27y, MET34y, PHE17z, PHE37y, PRO24z, PRO30z, PRO33y, SER29z, SER36z, TRP33z, TYR27z, VAL13z, VAL20z, VAL23z, VAL25z