3AQE

crystal structure of the extracellular domain of human ramp2

• Total interactions analyzed: 15
• Total true interactions: 9
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 60
  • Norm. En. per Res.: -3.9419
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-35.7324	3.3664	-182.674	-215.04	62	5	3	7008	2	12	8
A-C	-48.8949	-3.4581	-184.161	-236.514	60	7	4	7168	2	11	8
B-C	-21.0152	1.5619	-148.066	-167.5193	52	2	2	5467	2	12	8
B-D	0.0	7.5187	-9.232	-1.7132	10	0	0	331	0	4	6
C-D	0.0	1.2063	-40.9709	-39.7646	42	1	0	2404	1	24	18
C-E	0.0	14.3115	-6.7536	7.558	11	0	0	285	0	4	6
D-E	-24.6077	-1.4725	-160.007	-186.0872	58	4	2	6356	2	12	8
D-F	-22.2466	-8.2041	-180.825	-211.2757	59	6	4	7170	2	11	8
E-F	-36.1891	2.1755	-189.732	-223.7456	62	6	4	7188	2	11	8

Interface residues

• A-B: ALA104A, ALA116A, ALA129B, ALA87B, ARG118A, ARG91B, ARG97A, ARG97B, ASN113A, ASN130B, ASN60A, ASN70A, ASP108A, ASP85B, ASP98B, CYS131B, CYS84B, GLN125B, GLN135B, GLN66A, GLU101B, GLU117A, GLU117B, GLU122A, GLU62A, GLY110A, HIS124B, HIS127B, ILE119A, ILE120A, ILE120B, ILE126B, ILE89B, LEU109A, LEU115A, LEU133B, LEU96B, PHE107A, PHE111A, PHE111B, PHE121A, PHE121B, PHE128B, PHE67A, PRO112A, PRO112B, PRO114A, PRO92B, SER132B, SER90B, SER94B, THR123B, THR63A, THR95B, TRP69A, TRP83B, TRP86B, TYR61A, TYR72B, TYR93B, VAL134B, VAL65A
• A-C: ALA104C, ALA116C, ALA129A, ALA64C, ALA87A, ARG118C, ARG91A, ARG97A, ARG97C, ASN113C, ASN130A, ASN60C, ASN70C, ASP108C, ASP85A, ASP98A, CYS131A, CYS84A, GLN125A, GLN135A, GLN66C, GLU117A, GLU117C, GLU122C, GLU62C, GLY110C, HIS124A, HIS127A, ILE119C, ILE120A, ILE120C, ILE89A, LEU109C, LEU115C, LEU133A, LEU96A, PHE107C, PHE111A, PHE111C, PHE121A, PHE121C, PHE128A, PHE67C, PRO112A, PRO112C, PRO114C, PRO92A, SER132A, SER90A, SER94A, THR123A, THR63C, TRP69C, TRP83A, TRP86A, TYR61C, TYR72A, TYR93A, VAL134A, VAL65C
• B-C: ALA104B, ALA116B, ALA129C, ALA87C, ARG118B, ARG91C, ARG97B, ARG97C, ASN113B, ASN130C, ASN60B, ASP108B, ASP85C, ASP98C, CYS131C, CYS84C, GLN125C, GLU117B, GLU117C, GLU62B, GLY110B, HIS124C, HIS127C, ILE119B, ILE120B, ILE120C, ILE126C, ILE89C, LEU109B, LEU115B, LEU96C, PHE107B, PHE111B, PHE111C, PHE121B, PHE121C, PHE128C, PRO112B, PRO112C, PRO114B, PRO92C, SER132C, SER90C, SER94C, THR123C, THR95C, TRP83C, TRP86C, TYR61B, TYR72C, TYR93C, VAL65B
• B-D: ASP108B, ASP74D, ASP77D, GLN75D, GLY110B, ILE79D, LEU106B, LEU109B, PHE107B, PRO78D
• C-D: ALA64C, ALA64D, ARG91C, ARG91D, ASP82C, ASP82D, ASP98C, ASP98D, CYS99C, CYS99D, GLN75C, GLN75D, GLU101C, GLU101D, HIS102C, HIS102D, HIS71C, HIS71D, ILE79C, ILE79D, ILE89C, ILE89D, LEU106C, LEU106D, LEU96C, PHE103C, PHE103D, PHE107C, PHE107D, PHE67C, PHE67D, PRO78C, PRO78D, PRO92C, PRO92D, SER90C, SER90D, SER94C, SER94D, THR95C, THR95D, TYR93C
• C-E: ASP108E, ASP74C, ASP77C, GLN75C, GLY110E, HIS71C, ILE79C, LEU106E, LEU109E, PHE107E, PRO78C
• D-E: ALA104E, ALA116E, ALA129D, ALA87D, ARG118E, ARG91D, ARG97D, ARG97E, ASN113E, ASN130D, ASN60E, ASP108E, ASP85D, ASP98D, CYS131D, CYS84D, GLN125D, GLN125E, GLN66E, GLU101D, GLU117D, GLU117E, GLU122E, GLU62E, GLY110E, HIS124D, HIS127D, ILE119E, ILE120D, ILE120E, ILE89D, LEU109E, LEU115E, LEU133D, LEU96D, PHE107E, PHE111D, PHE111E, PHE121D, PHE121E, PHE128D, PRO112D, PRO112E, PRO114E, PRO92D, SER132D, SER90D, SER94D, THR123D, THR63E, THR95D, TRP69E, TRP83D, TRP86D, TYR61E, TYR72D, TYR93D, VAL65E
• D-F: ALA104D, ALA116D, ALA129F, ALA64D, ALA87F, ARG118D, ARG91F, ARG97D, ARG97F, ASN113D, ASN130F, ASN60D, ASN70D, ASP108D, ASP85F, ASP98F, CYS131F, CYS84F, GLN125F, GLN66D, GLU117D, GLU117F, GLU122D, GLU62D, GLY110D, HIS124F, HIS127F, ILE119D, ILE120D, ILE120F, ILE89F, LEU109D, LEU115D, LEU133F, LEU96F, PHE107D, PHE111D, PHE111F, PHE121D, PHE121F, PHE128F, PHE67D, PRO112D, PRO112F, PRO114D, PRO92F, SER132F, SER90F, SER94F, THR123F, THR63D, TRP69D, TRP83F, TRP86F, TYR61D, TYR72F, TYR93F, VAL134F, VAL65D
• E-F: ALA104F, ALA116F, ALA129E, ALA64F, ALA87E, ARG118F, ARG91E, ARG97E, ARG97F, ASN113F, ASN130E, ASN60F, ASN70F, ASP108F, ASP85E, ASP98E, CYS131E, CYS84E, GLN125E, GLN135E, GLN66F, GLU101E, GLU117E, GLU117F, GLU122F, GLU62F, GLY110F, HIS124E, HIS127E, ILE119F, ILE120E, ILE120F, ILE126E, ILE89E, LEU109F, LEU115F, LEU133E, LEU96E, PHE107F, PHE111E, PHE111F, PHE121E, PHE121F, PHE128E, PRO112E, PRO112F, PRO114F, PRO92E, SER132E, SER90E, SER94E, THR123E, THR63F, THR95E, TRP69F, TRP83E, TRP86E, TYR61F, TYR72E, TYR93E, VAL134E, VAL65F