3AM8

crystal structure of a human major histocompatibilty complex

• Total interactions analyzed: 15
• Total true interactions: 5
• Strongest Interaction:
  • Chains: B-D
  • Int. Res.: 132
  • Norm. En. per Res.: -4.5632
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-2.9541	-6.238	-19.8497	-29.0418	38	0	0	1451	3	37	43
A-C	-69.3212	-126.2404	-378.202	-573.7636	129	17	2	13510	7	47	40
A-E	-38.4322	-21.3102	-252.682	-312.4244	86	13	2	10013	2	6	8
B-D	-84.2149	-126.7942	-391.328	-602.3372	132	24	2	13576	7	45	40
B-F	-26.2187	-29.0864	-257.717	-313.0221	84	14	4	10076	2	5	9

Interface residues

• A-B: ARG107A, ARG107B, ARG108A, ARG108B, ASP106A, ASP106B, ASP162A, GLN54A, GLU166A, GLU173A, GLU173B, GLU177B, GLU264B, GLU268B, GLU53A, GLU55A, GLY1B, HIS169A, HIS181A, HIS181B, HIS3B, LEU172B, LEU180A, LEU180B, LEU182A, LEU182B, LYS170A, LYS174A, LYS176A, LYS176B, LYS186B, PRO105B, PRO184B, PRO267B, SER2B, THR163A, TRP167A, VAL165A
• A-C: ALA117A, ALA15C, ALA236A, ALA246A, ARG111A, ARG12C, ARG14A, ARG17A, ARG202A, ARG21A, ARG234A, ARG35A, ARG3C, ARG48A, ARG97C, ASN21C, ASN24C, ASP119A, ASP122A, ASP238A, ASP30A, ASP34C, ASP37A, ASP53C, ASP59C, ASP96C, ASP98C, CYS25C, GLN115A, GLN242A, GLN2C, GLN32A, GLN87A, GLN8C, GLN96A, GLU114A, GLU229A, GLU232A, GLU50C, GLY120A, GLY207A, GLY237A, GLY239A, GLY26A, GLY29C, GLY91A, HIS13C, HIS188A, HIS191A, HIS192A, HIS31C, HIS51C, HIS93A, HIS99A, HIS9A, ILE1C, ILE23A, ILE7C, LEU124A, LEU206A, LEU230A, LEU54C, LEU64C, LEU65C, LEU95A, LYS121A, LYS186A, LYS243A, LYS58C, LYS6A, LYS6C, MET0C, MET98A, MET99C, PHE116A, PHE22A, PHE22C, PHE241A, PHE30C, PHE36A, PHE56C, PHE62C, PHE74A, PHE8A, PRO14C, PRO235A, PRO32C, PRO47A, SER11A, SER11C, SER13A, SER24A, SER28C, SER33C, SER52C, SER55C, SER57C, SER61C, SER92A, THR10A, THR125A, THR190A, THR200A, THR233A, THR240A, THR94A, TRP204A, TRP244A, TRP60C, TRP95C, TRP97A, TYR10C, TYR113A, TYR118A, TYR123A, TYR26C, TYR27A, TYR63C, TYR66C, TYR67C, TYR7A, VAL12A, VAL136A, VAL231A, VAL25A, VAL27C, VAL34A, VAL46A, VAL9C
• A-E: ALA117A, ALA140A, ALA150A, ALA153A, ALA158A, ALA67A, ALA71A, ARG5E, ARG62A, ARG65A, ARG68A, ARG75A, ASN148A, ASN77A, ASP69A, CYS101A, CYS164A, GLN156A, GLN72A, GLN96A, GLU114A, GLU144A, GLU152A, GLU154A, GLU166A, GLU63A, GLY26A, GLY3E, HIS155A, HIS99A, HIS9A, ILE142A, ILE73A, ILE8E, LEU124A, LEU126A, LEU160A, LEU168A, LEU5A, LEU78A, LEU7E, LEU81A, LEU95A, LEU9E, LYS146A, LYS170A, LYS6A, MET2E, MET45A, MET52A, PHE116A, PHE22A, PHE33A, PHE36A, PHE74A, PHE8A, PRO4E, SER143A, SER147A, SER151A, SER24A, SER66A, THR125A, THR134A, THR163A, THR64A, THR6E, THR70A, THR80A, TRP133A, TRP167A, TRP60A, TRP97A, TYR118A, TYR123A, TYR159A, TYR171A, TYR59A, TYR7A, TYR84A, VAL165A, VAL1E, VAL25A, VAL28A, VAL34A, VAL76A
• B-D: ALA117B, ALA15D, ALA236B, ALA246B, ARG111B, ARG12D, ARG14B, ARG17B, ARG202B, ARG21B, ARG234B, ARG35B, ARG3D, ARG48B, ARG97D, ASN21D, ASN24D, ASP119B, ASP122B, ASP238B, ASP30B, ASP34D, ASP37B, ASP53D, ASP59D, ASP96D, ASP98D, CYS25D, GLN115B, GLN242B, GLN2D, GLN32B, GLN87B, GLN8D, GLN96B, GLU102B, GLU114B, GLU229B, GLU232B, GLU50D, GLU89B, GLY120B, GLY207B, GLY237B, GLY239B, GLY26B, GLY29D, HIS13D, HIS188B, HIS191B, HIS192B, HIS31D, HIS51D, HIS93B, HIS99B, HIS9B, ILE1D, ILE23B, ILE7D, LEU124B, LEU206B, LEU230B, LEU54D, LEU64D, LEU65D, LEU95B, LYS121B, LYS186B, LYS243B, LYS58D, LYS6B, LYS6D, MET0D, MET98B, MET99D, PHE116B, PHE22B, PHE22D, PHE241B, PHE30D, PHE36B, PHE56D, PHE62D, PHE74B, PHE8B, PRO14D, PRO193B, PRO235B, PRO32D, SER11B, SER11D, SER13B, SER24B, SER28D, SER33D, SER52D, SER55D, SER57D, SER61D, SER88B, SER92B, THR10B, THR125B, THR190B, THR200B, THR233B, THR240B, THR94B, TRP204B, TRP244B, TRP60D, TRP95D, TRP97B, TYR10D, TYR113B, TYR118B, TYR123B, TYR26D, TYR27B, TYR63D, TYR66D, TYR67D, TYR7B, TYR85B, VAL12B, VAL136B, VAL231B, VAL25B, VAL27D, VAL34B, VAL46B, VAL9D
• B-F: ALA117B, ALA140B, ALA150B, ALA153B, ALA158B, ALA67B, ALA71B, ARG157B, ARG5F, ARG62B, ARG65B, ARG68B, ARG75B, ASN148B, ASN77B, ASP69B, CYS164B, GLN115B, GLN156B, GLN72B, GLN96B, GLU114B, GLU144B, GLU152B, GLU154B, GLU166B, GLU63B, GLY26B, GLY3F, HIS155B, HIS99B, HIS9B, ILE142B, ILE73B, ILE8F, LEU124B, LEU126B, LEU160B, LEU168B, LEU5B, LEU78B, LEU7F, LEU81B, LEU95B, LEU9F, LYS146B, LYS170B, LYS174B, MET2F, MET45B, MET52B, PHE116B, PHE22B, PHE33B, PHE36B, PHE74B, PRO4F, SER143B, SER147B, SER151B, SER24B, SER66B, THR125B, THR163B, THR64B, THR6F, THR70B, THR80B, TRP133B, TRP167B, TRP97B, TYR118B, TYR123B, TYR159B, TYR171B, TYR59B, TYR7B, TYR84B, VAL165B, VAL1F, VAL25B, VAL28B, VAL34B, VAL76B