3ALX

crystal structure of the measles virus hemagglutinin bound to its cellular receptor slam (mv-h(l482r)-slam(n102h/r108y) fusion)

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: B-D
  • Int. Res.: 104
  • Norm. En. per Res.: -2.6582
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	3.6111	-63.5279	-59.9168	52	7	0	2243	0	7	4
A-C	-21.4224	4.5435	-225.588	-242.467	102	15	5	11087	0	15	15
A-D	-15.1718	-2.8093	-159.026	-177.0072	84	14	2	7527	0	15	18
B-C	-12.891	-2.3458	-212.403	-227.6398	89	15	1	8839	0	14	19
B-D	-27.3483	2.1721	-251.276	-276.4523	104	16	5	11326	0	16	15

Interface residues

• A-B: ARG547A, ARG547B, ASN262A, ASN262B, ASN447A, ASN447B, ASN449A, ASN449B, ASN450A, ASN450B, ASP521A, ASP521B, ASP574A, ASP574B, CYS188A, CYS188B, CYS606A, CYS606B, GLN225A, GLN225B, GLN520A, GLN520B, GLN523A, GLN575A, GLN575B, GLY226A, GLY226B, GLY264B, GLY519A, GLY519B, HIS448A, HIS448B, LEU294A, LEU517A, LEU517B, LYS445B, MET227A, PRO263A, PRO263B, PRO518A, PRO518B, SER189A, SER189B, SER224A, SER446A, SER446B, THR572A, THR572B, TRP573B, TYR481A, VAL451B, VAL604B
• A-C: ALA267A, ALA267C, ARG212A, ARG212C, ARG261A, ARG261C, ASN200A, ASN200C, ASN238C, ASN262A, ASN262C, ASN274A, ASN274C, ASP207A, ASP207C, GLN197A, GLN197C, GLU235A, GLU235C, GLU256A, GLU256C, GLU277A, GLU277C, GLY211A, GLY211C, GLY258A, GLY258C, GLY264A, GLY264C, GLY266A, GLY266C, HIS271A, HIS271C, LEU203A, LEU203C, LEU205A, LEU205C, LEU206A, LEU206C, LEU208A, LEU208C, LEU210A, LEU239C, LEU265A, LEU265C, LEU276C, LEU294A, LEU294C, LYS236A, LYS236C, LYS328A, LYS328C, MET201A, MET201C, MET272A, MET272C, PHE198A, PHE198C, PHE270A, PHE270C, PRO237A, PRO237C, PRO263A, PRO263C, PRO268A, PRO330A, PRO330C, SER199A, SER199C, SER202A, SER202C, SER204A, SER204C, SER329A, SER329C, THR273A, THR273C, TRP327A, TRP327C, TYR209A, TYR209C, TYR214A, TYR214C, TYR228A, TYR228C, TYR232A, TYR252A, TYR252C, TYR275A, TYR275C, VAL234A, VAL234C, VAL254A, VAL254C, VAL257A, VAL257C, VAL259A, VAL259C, VAL269A, VAL269C, VAL326A, VAL326C
• A-D: ARG253D, ARG51A, ARG97A, ASN282D, ASN286D, ASN53A, ASP283D, ASP304D, ASP332D, CYS188A, CYS300D, CYS32A, CYS606A, GLN278D, GLN320D, GLN334D, GLN37A, GLN38A, GLU139A, GLU277D, GLU303D, GLU422D, GLU50A, GLY190A, GLY302D, HIS102A, HIS301D, HIS49A, ILE35A, ILE52A, LEU133A, LEU135A, LEU137A, LEU276D, LEU284D, LEU321D, LEU324D, LEU39A, LEU419D, LEU423D, LEU44A, LEU45A, LYS136A, LYS236D, LYS315D, LYS323D, LYS328D, LYS34A, LYS424D, MET251D, MET333D, PHE131A, PHE255D, PHE319D, PRO191A, PRO279D, PRO330D, PRO338D, PRO33A, PRO46A, SER189A, SER250D, SER281D, SER285D, SER318D, SER329D, SER335D, SER418D, SER41A, SER55A, THR331D, THR420D, THR48A, TRP336D, TYR138A, TYR252D, TYR99A, VAL280D, VAL317D, VAL322D, VAL337D, VAL36A, VAL421D, VAL43A
• B-C: ARG253C, ARG51B, ASN282C, ASN286C, ASN53B, ASP283C, ASP304C, ASP332C, CYS188B, CYS300C, CYS32B, CYS606B, GLN140B, GLN278C, GLN320C, GLN334C, GLN37B, GLN38B, GLU139B, GLU277C, GLU303C, GLU422C, GLU50B, GLY190B, GLY302C, GLY316C, HIS102B, HIS134B, HIS301C, HIS49B, ILE35B, ILE52B, LEU133B, LEU135B, LEU137B, LEU239C, LEU276C, LEU284C, LEU321C, LEU324C, LEU39B, LEU419C, LEU423C, LEU44B, LEU45B, LYS136B, LYS236C, LYS315C, LYS323C, LYS328C, LYS34B, LYS424C, MET333C, PHE131B, PHE255C, PHE319C, PRO191B, PRO237C, PRO279C, PRO330C, PRO338C, PRO33B, PRO46B, SER189B, SER281C, SER285C, SER318C, SER329C, SER335C, SER418C, SER41B, SER55B, THR331C, THR420C, THR48B, THR54B, TRP336C, TYR138B, TYR252C, TYR275C, TYR99B, VAL254C, VAL280C, VAL317C, VAL322C, VAL337C, VAL36B, VAL421C, VAL43B
• B-D: ALA267B, ALA267D, ARG212B, ARG212D, ARG261B, ARG261D, ASN200B, ASN200D, ASN238B, ASN262B, ASN262D, ASN274B, ASN274D, ASP207B, ASP207D, ASP574D, GLN197B, GLU235B, GLU235D, GLU256B, GLU256D, GLU277B, GLU277D, GLY211B, GLY213B, GLY258B, GLY258D, GLY264B, GLY264D, GLY266B, GLY266D, HIS271B, HIS271D, LEU203B, LEU203D, LEU205B, LEU205D, LEU206B, LEU206D, LEU208B, LEU208D, LEU210B, LEU210D, LEU239B, LEU265B, LEU265D, LEU276B, LEU276D, LEU294D, LYS236B, LYS236D, LYS328B, LYS328D, MET201B, MET201D, MET272B, MET272D, PHE198B, PHE198D, PHE270B, PHE270D, PRO237B, PRO237D, PRO263B, PRO263D, PRO268B, PRO330B, PRO330D, SER199B, SER199D, SER202B, SER202D, SER204B, SER204D, SER241B, SER329B, SER329D, THR273B, THR273D, TRP327B, TRP327D, TRP573D, TYR209B, TYR209D, TYR214B, TYR214D, TYR228B, TYR228D, TYR252B, TYR252D, TYR275B, TYR275D, VAL234B, VAL234D, VAL254B, VAL254D, VAL257B, VAL257D, VAL259B, VAL259D, VAL269B, VAL269D, VAL326B, VAL326D