3AB3

crystal structure of p115rhogef rgs domain in complex with g alpha 13

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 138
  • Norm. En. per Res.: -4.0342
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-86.1001	-99.3277	-385.41	-570.8378	143	28	6	15669	9	76	56
A-C	0.0	12.6503	-12.2765	0.3738	25	2	0	711	0	6	6
B-C	-8.1941	-29.8898	-97.0826	-135.1665	65	7	0	4457	1	17	20
B-D	0.0	0.0	-0.1202	-0.1202	8	0	0	56	0	2	3
C-D	-99.6425	-83.1368	-373.934	-556.7133	138	28	7	15289	10	69	50

Interface residues

• A-B: ALA102A, ALA129A, ALA132A, ALA133A, ALA161A, ALA173B, ALA26B, ALA67B, ARG103A, ARG128A, ARG152B, ARG161B, ARG164A, ARG165A, ARG200A, ARG201A, ARG227A, ARG230A, ARG232A, ARG260A, ARG264A, ARG279A, ARG335A, ARG97A, ASN270A, ASN277A, ASN278A, ASN283A, ASN33B, ASN91A, ASP101A, ASP126A, ASP156B, ASP238A, ASP259A, ASP28B, ASP30B, GLN134A, GLN153B, GLN169A, GLN170B, GLN205B, GLN226A, GLN64B, GLN69B, GLU104A, GLU167A, GLU169B, GLU171B, GLU229A, GLU235A, GLU258A, GLU267A, GLU273A, GLU27B, GLU29B, GLU32B, GLU34B, GLU58A, GLU71B, GLY135A, GLY164B, GLY171A, GLY205A, GLY224A, GLY225A, GLY25B, GLY55A, GLY57A, GLY73B, GLY95A, HIS107A, HIS200B, HIS206B, HIS65B, ILE108A, ILE208B, ILE23B, ILE24B, ILE271A, ILE275A, ILE93A, LEU106A, LEU162B, LEU170A, LEU172B, LEU256A, LEU269A, LEU54A, LEU68B, LEU99A, LYS105A, LYS160B, LYS204A, LYS214B, LYS231A, LYS333A, LYS94A, MET123A, MET163B, MET165B, MET204B, MET257A, MET96A, PHE157B, PHE168A, PHE234A, PHE237A, PHE245A, PHE272A, PHE281A, PHE31B, PHE70B, PRO167B, PRO202A, PRO72B, SER159B, SER209B, SER215B, SER228A, SER22B, SER239A, SER268A, SER282A, SER90A, THR127A, THR166B, THR203A, THR207B, THR210B, THR262A, THR266A, THR274A, TRP168B, TRP233A, VAL100A, VAL174A, VAL218B, VAL276A, VAL280A, VAL284A, VAL66B, VAL98A
• A-C: ARG140C, ARG150C, ASN263A, ASN270A, ASP188C, GLN144C, GLN261A, GLU273A, GLU311A, GLU313A, GLY185C, LEU143C, LEU146C, LEU310A, LYS121C, LYS306A, LYS333A, PHE309A, PHE312A, PRO147C, PRO187C, THR139C, THR262A, THR266A, VAL186C
• B-C: ALA129C, ALA132C, ALA133C, ALA149B, ARG128C, ARG137B, ARG140C, ARG152B, ARG158B, ARG201C, ARG232C, ARG79C, ASN117B, ASP126C, ASP156B, ASP210C, GLN134C, GLN140B, GLN144B, GLN146B, GLN147B, GLN153B, GLN47B, GLN51B, GLU138C, GLU141B, GLU155B, GLU208C, GLU235C, GLU82C, GLU83C, GLY135C, GLY151B, GLY205C, HIS207C, ILE206C, LEU154B, LEU162B, LEU49B, LYS160B, LYS204C, LYS219C, MET131C, MET136C, MET163B, PHE120B, PHE125C, PHE157B, PHE234C, PHE46B, PRO115B, PRO116B, PRO130C, PRO86C, SER145B, SER159B, SER48B, THR127C, THR203C, TYR209C, VAL137C, VAL141C, VAL148B, VAL150B, VAL221C
• B-D: ARG136B, ARG137B, ARG196D, GLN140B, GLN170D, GLN174D, HIS200D, VAL134B
• C-D: ALA102C, ALA129C, ALA132C, ALA133C, ALA161C, ALA173D, ALA26D, ALA67D, ARG103C, ARG128C, ARG152D, ARG161D, ARG164C, ARG165C, ARG200C, ARG201C, ARG227C, ARG230C, ARG232C, ARG260C, ARG264C, ARG279C, ARG335C, ARG97C, ASN270C, ASN277C, ASN278C, ASN283C, ASN91C, ASP101C, ASP126C, ASP156D, ASP211D, ASP238C, ASP259C, ASP28D, ASP30D, ASP336C, GLN134C, GLN153D, GLN169C, GLN170D, GLN226C, GLN64D, GLN69D, GLU104C, GLU167C, GLU169D, GLU171D, GLU229C, GLU235C, GLU258C, GLU267C, GLU273C, GLU27D, GLU29D, GLU32D, GLU58C, GLU71D, GLY135C, GLY164D, GLY171C, GLY205C, GLY224C, GLY225C, GLY25D, GLY55C, GLY57C, GLY73D, GLY95C, HIS107C, HIS206D, HIS65D, ILE108C, ILE208D, ILE23D, ILE24D, ILE271C, ILE275C, ILE93C, LEU106C, LEU122C, LEU162D, LEU170C, LEU256C, LEU269C, LEU54C, LEU68D, LEU99C, LYS105C, LYS160D, LYS204C, LYS214D, LYS231C, LYS333C, LYS94C, MET123C, MET163D, MET165D, MET204D, MET257C, MET96C, PHE168C, PHE234C, PHE237C, PHE245C, PHE272C, PHE281C, PHE31D, PHE70D, PRO167D, PRO202C, PRO72D, SER159D, SER209D, SER228C, SER22D, SER239C, SER268C, SER282C, SER90C, THR127C, THR166D, THR203C, THR207D, THR210D, THR262C, THR266C, THR274C, TRP168D, TRP233C, VAL100C, VAL174C, VAL218D, VAL276C, VAL280C, VAL66D, VAL98C