3AAE

crystal structure of actin capping protein in complex with carmil fragment

• Total interactions analyzed: 105
• Total true interactions: 31
• Strongest Interaction:
  • Chains: I-J
  • Int. Res.: 269
  • Norm. En. per Res.: -5.5717
• Hub Node: C(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-242.3388	-103.5792	-1185.8	-1531.718	276	52	25	46772	8	89	75
A-D	0.0	0.0	-14.273	-14.273	16	0	0	666	0	2	4
A-G	-11.6417	-30.4703	-68.6116	-110.7236	34	5	0	2992	2	5	4
A-X	-12.8011	40.5825	-139.912	-112.1306	56	11	2	5948	0	26	17
B-C	0.0	0.0	-0.0726	-0.0726	6	0	0	33	0	3	1
B-D	0.0	-1.1146	-114.032	-115.1466	39	6	7	4802	0	12	11
B-G	0.0	0.0	-23.0946	-23.0946	20	0	0	1067	0	0	0
B-X	-40.7571	-122.0568	-283.382	-446.1959	93	16	0	12384	13	61	33
C-D	-214.602	-89.7858	-1173.12	-1477.5078	269	43	25	45809	7	85	70
C-E	-9.6221	-43.4207	-74.8857	-127.9285	33	3	0	3206	4	5	3
C-F	0.0	0.0	-24.8914	-24.8914	19	0	0	1124	0	0	0
C-I	0.0	10.1062	-0.5936	9.5126	5	0	0	40	0	5	10
C-Y	-6.9806	39.763	-153.524	-120.7416	55	7	3	6363	0	27	19
D-H	0.0	4.0565	-38.2938	-34.2373	38	2	0	2399	1	22	20
D-Y	-37.519	-122.9869	-307.8	-468.3059	93	13	0	12416	12	64	32
E-F	-224.7534	-97.1698	-1172.06	-1493.9832	270	39	26	46119	6	83	69
E-J	0.0	0.0	-0.0447	-0.0447	8	0	0	18	0	1	3
E-Z	-14.4113	52.5504	-137.944	-99.8049	58	7	3	5859	0	25	17
F-H	0.0	12.3176	-8.107	4.2106	12	0	0	358	0	0	3
F-I	0.0	-3.8438	-13.4888	-17.3326	10	0	0	647	0	4	4
F-J	0.0	8.3622	-18.0648	-9.7026	38	0	0	1415	1	22	22
F-Z	-38.6308	-110.2243	-305.166	-454.0211	92	20	0	12630	10	62	33
G-H	-228.571	-84.6179	-1172.51	-1485.6989	269	46	25	46263	6	82	68
G-I	0.0	-28.6271	-67.0479	-95.675	33	3	0	2909	1	4	3
G-W	0.0	30.1025	-87.4721	-57.3696	45	2	1	3729	0	24	16
H-I	0.0	0.0	-27.6311	-27.6311	19	2	0	1187	0	0	0
H-W	-26.4235	-120.0541	-296.133	-442.6106	92	8	0	12194	12	63	31
I-J	-226.3553	-95.3641	-1177.07	-1498.7895	269	52	25	45969	7	85	68
I-V	0.0	36.9686	-90.2578	-53.2892	40	0	2	3942	0	23	13
J-Z	0.0	0.0	-0.2113	-0.2113	4	0	0	44	0	1	0
J-V	-40.985	-101.5893	-257.522	-400.0963	86	9	0	10277	9	55	29

Interface residues

• A-B: ALA100B, ALA103B, ALA130A, ALA137B, ALA17A, ALA18A, ALA211B, ALA235A, ALA242A, ALA248B, ALA24A, ALA257A, ALA9B, ARG108B, ARG14B, ARG15A, ARG15B, ARG172A, ARG174A, ARG195B, ARG215B, ARG225B, ARG244B, ARG259A, ARG260A, ARG260B, ARG37A, ARG7A, ASN102B, ASN138A, ASN167A, ASN170A, ASN180B, ASN188B, ASN203A, ASN212B, ASN222B, ASN229B, ASN234A, ASN237A, ASN241B, ASN246A, ASN24B, ASN272A, ASN30A, ASN34A, ASN41A, ASN42A, ASP105B, ASP109B, ASP10A, ASP11B, ASP134A, ASP139B, ASP149B, ASP201A, ASP205B, ASP211A, ASP219B, ASP238B, ASP247B, ASP251B, ASP252A, ASP270A, ASP27B, ASP30B, ASP35A, ASP72A, ASP7B, CYS147B, CYS8B, GLN106B, GLN162A, GLN164A, GLN178B, GLN195A, GLN196B, GLN19B, GLN205A, GLN20B, GLN240A, GLN248A, GLN253B, GLN257B, GLN261A, GLN4B, GLN5B, GLU113B, GLU12A, GLU159A, GLU200A, GLU218B, GLU221B, GLU230B, GLU233A, GLU236A, GLU238A, GLU245A, GLU261B, GLU28A, GLU31A, GLU99B, GLY114B, GLY115B, GLY138B, GLY139A, GLY146B, GLY171A, GLY183B, GLY185B, GLY190B, GLY191B, GLY202A, GLY214B, GLY234B, GLY242B, GLY27A, HIS135A, HIS152B, HIS161A, HIS197A, HIS209A, HIS209B, HIS23A, ILE132B, ILE134B, ILE144B, ILE158A, ILE16A, ILE194A, ILE210B, ILE212A, ILE213B, ILE21A, ILE21B, ILE224B, ILE231B, ILE232A, ILE239B, ILE243A, ILE246B, ILE249B, ILE269A, ILE274A, ILE29B, LEU10B, LEU110B, LEU12B, LEU16B, LEU175B, LEU177B, LEU189B, LEU192A, LEU193B, LEU206A, LEU216B, LEU228B, LEU243B, LEU258A, LEU258B, LEU25B, LEU262A, LEU275A, LEU28B, LEU31B, LEU35B, LEU38A, LEU39A, LEU39B, LEU40A, LEU45A, LEU46A, LEU6B, LEU96B, LYS133A, LYS135B, LYS136B, LYS13A, LYS142B, LYS143B, LYS145B, LYS181B, LYS193A, LYS19A, LYS210A, LYS223B, LYS235B, LYS237B, LYS23B, LYS254B, LYS256A, LYS268A, LYS273A, MET13B, MET174B, MET187B, MET220B, MET250A, PHE104B, PHE112B, PHE140A, PHE163A, PHE168A, PHE20A, PHE233B, PHE255A, PHE29A, PHE33A, PRO137A, PRO165A, PRO17B, PRO18B, PRO208B, PRO250B, PRO25A, PRO263A, PRO26A, PRO33B, SER150B, SER160A, SER171B, SER175A, SER184B, SER192B, SER206B, SER207B, SER208A, SER226B, SER244A, SER245B, SER251A, SER26B, SER276A, SER34B, THR172B, THR179B, THR182B, THR186B, THR194B, THR227B, THR22A, THR236B, THR241A, THR249A, THR253A, THR254A, THR265A, THR267A, TRP148B, TRP169A, TRP173A, TRP176B, TRP177A, TRP271A, TYR107B, TYR111B, TYR131A, TYR136A, TYR198A, TYR199A, TYR232B, TYR239A, TYR247A, VAL132A, VAL14A, VAL173B, VAL196A, VAL204A, VAL207A, VAL217B, VAL240B, VAL264A, VAL32A, VAL32B, VAL36A, VAL8A
• A-D: ARG129A, ASP71A, ASP72A, GLN259D, GLN264D, GLU68A, GLY69A, ILE67A, LEU262D, LEU266D, LYS133A, LYS66A, SER263D, TYR255D, TYR70A, VAL265D
• A-G: ALA186G, ARG260A, ARG266A, ASN272A, ASP214G, ASP270A, GLN187G, GLN213G, GLN217G, GLN223G, GLU227G, ILE231G, ILE269A, ILE274A, LEU275A, LYS268A, LYS273A, PHE228G, PRO184G, PRO263A, SER215G, SER219G, SER220G, SER276A, THR182G, THR185G, THR224G, THR265A, THR267A, TRP271A, VAL188G, VAL216G, VAL218G, VAL264A
• A-X: ALA50A, ARG102A, ARG37A, ARG47A, ARG984X, ARG985X, ASN167A, ASN170A, ASN203A, ASN30A, ASN34A, ASN42A, ASN44A, ASP201A, ASP35A, ASP43A, ASP99A, GLN164A, GLU200A, GLU28A, GLU31A, GLU48A, GLU977X, GLU981X, GLU982X, GLU987X, GLY202A, GLY27A, GLY983X, HIS100A, HIS197A, HIS988X, ILE21A, ILE975X, LEU101A, LEU38A, LEU46A, LEU974X, LEU978X, LEU986X, LYS103A, LYS166A, LYS97A, PHE163A, PHE168A, PHE29A, PHE33A, PHE54A, PHE989X, PRO165A, PRO979X, SER976X, SER980X, TRP169A, TYR199A, VAL32A
• B-C: ASN252B, ASP134C, GLU233C, HIS135C, LYS256B, TYR255B
• B-D: ALA248D, ARG260B, ARG260D, ASN252B, ASN252D, ASP247D, ASP251B, ASP251D, GLN253B, GLN253D, GLN257B, GLN257D, GLN259B, GLN259D, GLN264B, GLN264D, GLU261B, GLU261D, ILE246D, ILE249B, ILE249D, LEU258B, LEU258D, LEU262B, LEU262D, LEU266B, LYS254B, LYS254D, LYS256B, LYS256D, PRO250B, PRO250D, SER245D, SER263B, SER263D, TYR255B, TYR255D, VAL265B, VAL265D
• B-G: ALA103B, ALA186G, ARG108B, ASN102B, ASP105B, ASP109B, GLN106B, GLN187G, GLN217G, GLU113B, LEU110B, PRO183G, PRO184G, SER219G, THR182G, THR185G, TYR107B, TYR111B, VAL216G, VAL218G
• B-X: ALA129B, ALA87B, ALA9B, ARG14B, ARG15B, ARG195B, ARG66B, ARG72B, ARG984X, ARG985X, ARG993X, ARG996X, ASN65B, ASN997X, ASP11B, ASP123B, ASP125B, ASP38B, ASP3B, ASP44B, ASP63B, ASP67B, ASP69B, ASP7B, ASP85B, CYS36B, CYS62B, CYS8B, GLN1000X, GLN1001X, GLN157B, GLN196B, GLN45B, GLN4B, GLU155B, GLU37B, GLU84B, GLU977X, GLU981X, GLU982X, GLU987X, GLY130B, GLY68B, GLY86B, HIS152B, HIS988X, ILE151B, ILE29B, LEU10B, LEU121B, LEU124B, LEU12B, LEU133B, LEU169B, LEU193B, LEU39B, LEU40B, LEU6B, LEU83B, LEU986X, LEU992X, LYS168B, LYS991X, LYS995X, LYS998X, LYS999X, MET13B, MET88B, PHE128B, PHE989X, PRO1002X, PRO89B, PRO994X, SER171B, SER34B, SER41B, SER42B, SER70B, SER980X, THR170B, THR172B, THR194B, THR990X, TRP122B, TYR120B, TYR64B, TYR71B, TYR79B, VAL131B, VAL153B, VAL154B, VAL156B, VAL43B
• C-D: ALA100D, ALA103D, ALA130C, ALA137D, ALA17C, ALA18C, ALA211D, ALA235C, ALA242C, ALA248D, ALA24C, ALA257C, ALA9D, ARG108D, ARG14D, ARG15C, ARG15D, ARG172C, ARG174C, ARG195D, ARG215D, ARG225D, ARG244D, ARG259C, ARG260C, ARG37C, ARG7C, ASN102D, ASN138C, ASN167C, ASN170C, ASN180D, ASN188D, ASN203C, ASN212D, ASN222D, ASN229D, ASN234C, ASN237C, ASN241D, ASN246C, ASN24D, ASN272C, ASN30C, ASN34C, ASN41C, ASN42C, ASP105D, ASP109D, ASP10C, ASP11D, ASP134C, ASP139D, ASP149D, ASP201C, ASP205D, ASP211C, ASP219D, ASP238D, ASP247D, ASP251D, ASP252C, ASP270C, ASP27D, ASP30D, ASP35C, ASP7D, CYS147D, CYS8D, GLN106D, GLN162C, GLN164C, GLN178D, GLN195C, GLN196D, GLN19D, GLN205C, GLN20D, GLN240C, GLN248C, GLN261C, GLN4D, GLN5D, GLU113D, GLU12C, GLU159C, GLU200C, GLU218D, GLU221D, GLU230D, GLU233C, GLU236C, GLU238C, GLU245C, GLU28C, GLU31C, GLU99D, GLY114D, GLY115D, GLY138D, GLY139C, GLY146D, GLY171C, GLY183D, GLY185D, GLY190D, GLY191D, GLY202C, GLY214D, GLY234D, GLY242D, GLY27C, HIS135C, HIS152D, HIS161C, HIS197C, HIS209C, HIS209D, HIS23C, ILE132D, ILE134D, ILE144D, ILE158C, ILE16C, ILE194C, ILE210D, ILE212C, ILE213D, ILE21C, ILE21D, ILE224D, ILE231D, ILE232C, ILE239D, ILE243C, ILE246D, ILE249D, ILE269C, ILE274C, ILE29D, LEU10D, LEU110D, LEU12D, LEU16D, LEU175D, LEU177D, LEU189D, LEU192C, LEU193D, LEU206C, LEU216D, LEU228D, LEU243D, LEU258C, LEU25D, LEU262C, LEU275C, LEU28D, LEU31D, LEU35D, LEU38C, LEU39C, LEU39D, LEU40C, LEU45C, LEU46C, LEU6D, LEU96D, LYS133C, LYS135D, LYS136D, LYS13C, LYS142D, LYS143D, LYS145D, LYS181D, LYS193C, LYS19C, LYS210C, LYS223D, LYS235D, LYS237D, LYS23D, LYS256C, LYS268C, LYS273C, MET13D, MET174D, MET187D, MET220D, MET250C, PHE104D, PHE112D, PHE163C, PHE168C, PHE20C, PHE233D, PHE255C, PHE29C, PHE33C, PRO137C, PRO165C, PRO17D, PRO18D, PRO208D, PRO250D, PRO25C, PRO263C, PRO26C, PRO33D, SER150D, SER160C, SER171D, SER175C, SER184D, SER192D, SER206D, SER207D, SER208C, SER226D, SER244C, SER245D, SER251C, SER26D, SER276C, SER34D, SER9C, THR172D, THR179D, THR182D, THR186D, THR194D, THR227D, THR22C, THR236D, THR241C, THR249C, THR253C, THR254C, THR265C, THR267C, TRP148D, TRP169C, TRP173C, TRP176D, TRP177C, TRP271C, TYR107D, TYR111D, TYR131C, TYR136C, TYR198C, TYR199C, TYR232D, TYR239C, TYR247C, VAL132C, VAL14C, VAL173D, VAL196C, VAL204C, VAL207C, VAL217D, VAL240D, VAL264C, VAL32C, VAL32D, VAL36C, VAL8C
• C-E: ALA186C, ARG260E, ARG266E, ASN272E, ASP214C, ASP270E, GLN187C, GLN213C, GLN217C, GLN223C, GLU227C, ILE231C, ILE269E, ILE274E, LEU275E, LYS268E, LYS273E, PRO184C, PRO263E, SER215C, SER219C, SER220C, SER276E, THR182C, THR185C, THR224C, THR265E, THR267E, TRP271E, VAL188C, VAL216C, VAL218C, VAL264E
• C-F: ALA103F, ALA186C, ARG108F, ASP105F, ASP109F, GLN106F, GLN187C, GLN217C, GLU113F, LEU110F, PRO183C, PRO184C, SER219C, THR182C, THR185C, TYR107F, TYR111F, VAL216C, VAL218C
• C-I: ASP112I, GLN151C, GLU11C, GLU11I, GLY150C
• C-Y: ALA50C, ALA51C, ARG102C, ARG37C, ARG47C, ARG984Y, ARG985Y, ASN167C, ASN170C, ASN203C, ASN30C, ASN34C, ASN42C, ASN44C, ASP201C, ASP35C, ASP43C, ASP99C, GLN164C, GLU200C, GLU28C, GLU31C, GLU48C, GLU977Y, GLU981Y, GLU982Y, GLU987Y, GLY202C, GLY27C, GLY983Y, HIS100C, HIS197C, HIS988Y, ILE21C, ILE975Y, LEU101C, LEU40C, LEU45C, LEU46C, LEU978Y, LEU986Y, LYS103C, LYS166C, PHE163C, PHE168C, PHE29C, PHE33C, PHE54C, PHE989Y, PRO165C, PRO979Y, SER976Y, SER980Y, TYR199C, VAL32C
• D-H: ALA50D, ALA50H, ARG51D, ARG51H, ASP52D, ASP52H, ASP69D, ASP69H, ASP80D, ASP80H, GLY56D, GLY56H, ILE49D, ILE49H, LEU61D, LEU61H, LEU83D, LEU83H, LYS53D, LYS53H, LYS78D, LYS78H, PRO81D, PRO81H, PRO82D, PRO82H, SER70D, SER70H, TYR59D, TYR59H, TYR71D, TYR71H, TYR79D, TYR79H, VAL54D, VAL54H, VAL55D, VAL55H
• D-Y: ALA129D, ALA87D, ALA9D, ARG14D, ARG15D, ARG195D, ARG66D, ARG72D, ARG984Y, ARG985Y, ARG993Y, ARG996Y, ASN65D, ASN997Y, ASP11D, ASP123D, ASP125D, ASP38D, ASP3D, ASP44D, ASP63D, ASP67D, ASP69D, ASP7D, ASP85D, CYS36D, CYS62D, CYS8D, GLN1000Y, GLN1001Y, GLN157D, GLN196D, GLN45D, GLN4D, GLU155D, GLU37D, GLU84D, GLU981Y, GLU982Y, GLU987Y, GLY130D, GLY68D, GLY86D, HIS152D, HIS988Y, ILE151D, ILE29D, LEU10D, LEU121D, LEU124D, LEU12D, LEU133D, LEU169D, LEU193D, LEU35D, LEU39D, LEU40D, LEU6D, LEU83D, LEU986Y, LEU992Y, LYS168D, LYS991Y, LYS995Y, LYS998Y, LYS999Y, MET13D, MET88D, PHE128D, PHE989Y, PRO1002Y, PRO33D, PRO89D, PRO994Y, SER171D, SER41D, SER42D, SER70D, SER980Y, THR170D, THR172D, THR194D, THR990Y, TRP122D, TYR120D, TYR64D, TYR71D, TYR79D, VAL131D, VAL153D, VAL154D, VAL156D, VAL43D
• E-F: ALA100F, ALA103F, ALA130E, ALA137F, ALA17E, ALA18E, ALA211F, ALA235E, ALA242E, ALA248F, ALA24E, ALA257E, ALA9F, ARG108F, ARG14F, ARG15E, ARG15F, ARG172E, ARG174E, ARG195F, ARG215F, ARG225F, ARG244F, ARG259E, ARG260E, ARG37E, ARG7E, ASN102F, ASN138E, ASN167E, ASN170E, ASN180F, ASN188F, ASN203E, ASN212F, ASN222F, ASN229F, ASN234E, ASN237E, ASN241F, ASN246E, ASN24F, ASN252F, ASN272E, ASN30E, ASN34E, ASN41E, ASP105F, ASP109F, ASP10E, ASP11F, ASP134E, ASP139F, ASP149F, ASP201E, ASP205F, ASP211E, ASP219F, ASP238F, ASP247F, ASP251F, ASP252E, ASP270E, ASP27F, ASP30F, ASP35E, ASP3F, ASP7F, CYS147F, CYS36F, CYS8F, GLN106F, GLN162E, GLN164E, GLN178F, GLN195E, GLN196F, GLN19F, GLN205E, GLN20F, GLN240E, GLN248E, GLN261E, GLN4F, GLN5F, GLU113F, GLU12E, GLU159E, GLU200E, GLU218F, GLU221F, GLU230F, GLU233E, GLU236E, GLU238E, GLU245E, GLU28E, GLU31E, GLU99F, GLY114F, GLY115F, GLY138F, GLY139E, GLY146F, GLY171E, GLY183F, GLY185F, GLY190F, GLY191F, GLY202E, GLY214F, GLY234F, GLY242F, GLY27E, HIS135E, HIS152F, HIS161E, HIS197E, HIS209E, HIS209F, HIS23E, ILE132F, ILE134F, ILE144F, ILE158E, ILE16E, ILE194E, ILE210F, ILE212E, ILE213F, ILE21E, ILE21F, ILE224F, ILE231F, ILE232E, ILE239F, ILE243E, ILE246F, ILE249F, ILE269E, ILE274E, ILE29F, LEU10F, LEU110F, LEU12F, LEU16F, LEU175F, LEU177F, LEU189F, LEU192E, LEU193F, LEU206E, LEU216F, LEU228F, LEU243F, LEU258E, LEU25F, LEU262E, LEU275E, LEU28F, LEU31F, LEU35F, LEU38E, LEU39E, LEU39F, LEU40E, LEU45E, LEU46E, LEU6F, LEU96F, LYS133E, LYS135F, LYS136F, LYS13E, LYS142F, LYS143F, LYS145F, LYS181F, LYS193E, LYS19E, LYS210E, LYS223F, LYS235F, LYS237F, LYS23F, LYS256E, LYS268E, LYS273E, MET13F, MET174F, MET187F, MET220F, MET250E, PHE104F, PHE112F, PHE163E, PHE168E, PHE20E, PHE233F, PHE255E, PHE29E, PHE33E, PRO137E, PRO165E, PRO17F, PRO18F, PRO208F, PRO250F, PRO25E, PRO263E, PRO26E, PRO33F, SER150F, SER160E, SER175E, SER184F, SER192F, SER206F, SER207F, SER208E, SER226F, SER244E, SER245F, SER251E, SER26F, SER276E, SER34F, SER9E, THR172F, THR179F, THR182F, THR186F, THR194F, THR227F, THR22E, THR236F, THR241E, THR249E, THR253E, THR254E, THR265E, THR267E, TRP148F, TRP169E, TRP173E, TRP176F, TRP177E, TRP271E, TYR107F, TYR111F, TYR131E, TYR136E, TYR198E, TYR199E, TYR232F, TYR239E, TYR247E, VAL132E, VAL14E, VAL173F, VAL196E, VAL204E, VAL207E, VAL217F, VAL240F, VAL264E, VAL32E, VAL32F, VAL36E, VAL8E
• E-J: ARG15E, ARG51J, ARG7E, GLU12E, LYS19E, LYS53J, LYS78J, VAL54J
• E-Z: ALA50E, ALA51E, ARG102E, ARG37E, ARG47E, ARG7E, ARG984Z, ARG985Z, ASN167E, ASN170E, ASN203E, ASN30E, ASN34E, ASN42E, ASN44E, ASP201E, ASP35E, ASP43E, GLN164E, GLU200E, GLU28E, GLU31E, GLU48E, GLU977Z, GLU981Z, GLU982Z, GLU987Z, GLY202E, GLY27E, GLY983Z, HIS100E, HIS197E, HIS988Z, ILE21E, ILE975Z, LEU101E, LEU38E, LEU40E, LEU45E, LEU46E, LEU978Z, LEU986Z, LYS103E, LYS166E, PHE163E, PHE168E, PHE29E, PHE33E, PHE54E, PHE989Z, PRO1002Z, PRO165E, PRO979Z, SER976Z, SER980Z, TRP169E, TYR199E, VAL32E
• F-H: ALA248F, ALA248H, ASN252F, ASP247F, ASP247H, ASP251F, ASP251H, ILE246H, ILE249F, ILE249H, PRO250F, PRO250H
• F-I: ARG51F, ARG7I, ASP52F, GLY56F, LYS53F, LYS57F, SER9I, VAL54F, VAL55F, VAL8I
• F-J: ALA50F, ARG51F, ARG51J, ARG66F, ARG66J, ASN24F, ASP27F, ASP30F, ASP30J, ASP67J, ASP69F, ASP69J, ASP80F, ASP85J, CYS36J, GLU22F, GLU84F, GLU84J, GLY68F, GLY68J, ILE29J, LEU40J, LEU61F, LEU83F, LEU83J, LYS23F, LYS48F, LYS53F, LYS53J, PRO81F, PRO81J, PRO82F, PRO82J, SER26F, SER26J, SER70F, SER70J, TYR71F
• F-Z: ALA129F, ALA87F, ALA9F, ARG14F, ARG15F, ARG195F, ARG66F, ARG72F, ARG984Z, ARG985Z, ARG993Z, ARG996Z, ASN65F, ASN997Z, ASP11F, ASP123F, ASP125F, ASP38F, ASP3F, ASP44F, ASP63F, ASP67F, ASP69F, ASP7F, ASP85F, CYS36F, CYS62F, CYS8F, GLN1000Z, GLN1001Z, GLN157F, GLN196F, GLN45F, GLN4F, GLU155F, GLU37F, GLU84F, GLU981Z, GLU982Z, GLU987Z, GLY130F, GLY68F, GLY86F, GLY983Z, HIS152F, HIS988Z, ILE151F, ILE29F, LEU10F, LEU121F, LEU124F, LEU12F, LEU133F, LEU169F, LEU193F, LEU39F, LEU40F, LEU6F, LEU83F, LEU986Z, LEU992Z, LYS168F, LYS991Z, LYS995Z, LYS998Z, LYS999Z, MET13F, MET88F, PHE128F, PHE989Z, PRO1002Z, PRO89F, PRO994Z, SER171F, SER41F, SER42F, SER70F, SER980Z, THR170F, THR172F, THR194F, THR990Z, TRP122F, TYR120F, TYR64F, TYR71F, TYR79F, VAL131F, VAL153F, VAL154F, VAL156F, VAL43F
• G-H: ALA100H, ALA103H, ALA130G, ALA137H, ALA17G, ALA18G, ALA211H, ALA235G, ALA242G, ALA248H, ALA24G, ALA257G, ALA9H, ARG108H, ARG14H, ARG15G, ARG15H, ARG172G, ARG174G, ARG195H, ARG215H, ARG225H, ARG244H, ARG259G, ARG260G, ARG37G, ARG7G, ASN102H, ASN138G, ASN167G, ASN170G, ASN180H, ASN188H, ASN203G, ASN212H, ASN222H, ASN229H, ASN234G, ASN237G, ASN241H, ASN246G, ASN24H, ASN272G, ASN30G, ASN34G, ASN41G, ASN42G, ASP105H, ASP109H, ASP10G, ASP11H, ASP134G, ASP139H, ASP149H, ASP201G, ASP205H, ASP211G, ASP219H, ASP238H, ASP247H, ASP251H, ASP252G, ASP270G, ASP27H, ASP30H, ASP35G, ASP7H, CYS147H, CYS8H, GLN106H, GLN162G, GLN164G, GLN178H, GLN195G, GLN196H, GLN19H, GLN205G, GLN20H, GLN240G, GLN248G, GLN261G, GLN4H, GLN5H, GLU113H, GLU12G, GLU159G, GLU200G, GLU218H, GLU221H, GLU230H, GLU233G, GLU236G, GLU238G, GLU245G, GLU28G, GLU31G, GLU99H, GLY114H, GLY115H, GLY138H, GLY139G, GLY146H, GLY171G, GLY183H, GLY185H, GLY190H, GLY191H, GLY202G, GLY214H, GLY234H, GLY242H, GLY27G, HIS135G, HIS152H, HIS161G, HIS197G, HIS209G, HIS209H, HIS23G, ILE132H, ILE134H, ILE144H, ILE158G, ILE16G, ILE194G, ILE210H, ILE212G, ILE213H, ILE21G, ILE21H, ILE224H, ILE231H, ILE232G, ILE239H, ILE243G, ILE246H, ILE249H, ILE269G, ILE274G, ILE29H, LEU10H, LEU110H, LEU12H, LEU16H, LEU175H, LEU177H, LEU189H, LEU192G, LEU193H, LEU206G, LEU216H, LEU228H, LEU243H, LEU258G, LEU25H, LEU262G, LEU275G, LEU28H, LEU31H, LEU35H, LEU38G, LEU39G, LEU39H, LEU40G, LEU45G, LEU46G, LEU6H, LEU96H, LYS133G, LYS135H, LYS136H, LYS13G, LYS142H, LYS143H, LYS145H, LYS181H, LYS193G, LYS19G, LYS210G, LYS223H, LYS235H, LYS237H, LYS23H, LYS256G, LYS268G, LYS273G, MET13H, MET174H, MET187H, MET220H, MET250G, PHE104H, PHE112H, PHE163G, PHE168G, PHE20G, PHE233H, PHE255G, PHE29G, PHE33G, PRO137G, PRO165G, PRO17H, PRO18H, PRO208H, PRO250H, PRO25G, PRO263G, PRO26G, PRO33H, SER150H, SER160G, SER175G, SER184H, SER192H, SER204H, SER206H, SER207H, SER208G, SER226H, SER244G, SER245H, SER251G, SER26H, SER276G, SER34H, SER9G, THR172H, THR179H, THR182H, THR186H, THR194H, THR227H, THR22G, THR236H, THR241G, THR249G, THR253G, THR254G, THR265G, THR267G, TRP148H, TRP169G, TRP173G, TRP176H, TRP177G, TRP271G, TYR107H, TYR111H, TYR131G, TYR136G, TYR198G, TYR199G, TYR232H, TYR239G, TYR247G, VAL132G, VAL14G, VAL173H, VAL196G, VAL204G, VAL207G, VAL217H, VAL240H, VAL264G, VAL32G, VAL32H, VAL36G, VAL8G
• G-I: ALA186I, ARG260G, ARG266G, ASN272G, ASP214I, ASP270G, GLN187I, GLN213I, GLN217I, GLN223I, GLU227I, ILE231I, ILE269G, ILE274G, LEU275G, LYS268G, LYS273G, PRO184I, PRO263G, SER215I, SER219I, SER220I, SER276G, THR182I, THR185I, THR224I, THR265G, THR267G, TRP271G, VAL188I, VAL216I, VAL218I, VAL264G
• G-W: ARG102G, ARG37G, ARG984W, ARG985W, ASN167G, ASN170G, ASN203G, ASN30G, ASN34G, ASP201G, ASP35G, ASP43G, GLN164G, GLU200G, GLU28G, GLU31G, GLU977W, GLU981W, GLU982W, GLU987W, GLY202G, GLY27G, GLY983W, HIS100G, HIS197G, HIS988W, LEU101G, LEU38G, LEU46G, LEU978W, LEU986W, LYS103G, LYS166G, PHE163G, PHE168G, PHE29G, PHE33G, PHE54G, PHE989W, PRO165G, PRO979W, SER980W, TRP169G, TYR199G, VAL32G
• H-I: ALA103H, ALA186I, ARG108H, ASP105H, ASP109H, GLN106H, GLN187I, GLN217I, GLU113H, LEU110H, PRO183I, PRO184I, SER219I, THR182I, THR185I, TYR107H, TYR111H, VAL216I, VAL218I
• H-W: ALA129H, ALA87H, ALA9H, ARG14H, ARG15H, ARG195H, ARG66H, ARG72H, ARG984W, ARG985W, ARG993W, ARG996W, ASN65H, ASN997W, ASP11H, ASP123H, ASP125H, ASP38H, ASP3H, ASP44H, ASP63H, ASP67H, ASP69H, ASP7H, ASP85H, CYS36H, CYS62H, CYS8H, GLN1000W, GLN1001W, GLN157H, GLN196H, GLN45H, GLN4H, GLU155H, GLU37H, GLU84H, GLU981W, GLU982W, GLU987W, GLY130H, GLY68H, GLY86H, GLY983W, HIS152H, HIS988W, ILE151H, ILE29H, LEU10H, LEU121H, LEU124H, LEU12H, LEU133H, LEU169H, LEU193H, LEU39H, LEU40H, LEU6H, LEU83H, LEU986W, LEU992W, LYS168H, LYS991W, LYS995W, LYS998W, LYS999W, MET13H, MET88H, PHE128H, PHE989W, PRO1002W, PRO89H, PRO994W, SER171H, SER41H, SER42H, SER70H, SER980W, THR170H, THR172H, THR194H, THR990W, TRP122H, TYR120H, TYR64H, TYR71H, TYR79H, VAL131H, VAL153H, VAL154H, VAL156H, VAL43H
• I-J: ALA100J, ALA103J, ALA130I, ALA137J, ALA17I, ALA18I, ALA211J, ALA235I, ALA242I, ALA248J, ALA24I, ALA257I, ALA9J, ARG108J, ARG14J, ARG15I, ARG15J, ARG172I, ARG174I, ARG195J, ARG215J, ARG225J, ARG244J, ARG259I, ARG260I, ARG37I, ARG7I, ASN102J, ASN138I, ASN167I, ASN170I, ASN180J, ASN188J, ASN203I, ASN212J, ASN222J, ASN229J, ASN234I, ASN237I, ASN241J, ASN246I, ASN24J, ASN272I, ASN30I, ASN34I, ASN41I, ASN42I, ASP105J, ASP109J, ASP10I, ASP11J, ASP134I, ASP139J, ASP149J, ASP201I, ASP205J, ASP211I, ASP219J, ASP238J, ASP247J, ASP251J, ASP252I, ASP270I, ASP27J, ASP30J, ASP35I, ASP7J, CYS147J, CYS8J, GLN106J, GLN162I, GLN164I, GLN178J, GLN195I, GLN196J, GLN19J, GLN205I, GLN20J, GLN240I, GLN248I, GLN261I, GLN4J, GLN5J, GLU113J, GLU12I, GLU159I, GLU200I, GLU218J, GLU221J, GLU230J, GLU233I, GLU236I, GLU238I, GLU245I, GLU28I, GLU31I, GLU99J, GLY114J, GLY115J, GLY138J, GLY139I, GLY146J, GLY171I, GLY183J, GLY185J, GLY190J, GLY191J, GLY202I, GLY214J, GLY234J, GLY242J, GLY27I, HIS135I, HIS152J, HIS161I, HIS197I, HIS209I, HIS209J, HIS23I, ILE132J, ILE134J, ILE144J, ILE158I, ILE16I, ILE194I, ILE210J, ILE212I, ILE213J, ILE21I, ILE21J, ILE224J, ILE231J, ILE232I, ILE239J, ILE243I, ILE246J, ILE249J, ILE269I, ILE274I, ILE29J, LEU10J, LEU110J, LEU12J, LEU16J, LEU175J, LEU177J, LEU189J, LEU192I, LEU193J, LEU206I, LEU216J, LEU228J, LEU243J, LEU258I, LEU25J, LEU262I, LEU275I, LEU28J, LEU31J, LEU35J, LEU38I, LEU39I, LEU39J, LEU40I, LEU45I, LEU46I, LEU6J, LEU96J, LYS133I, LYS135J, LYS136J, LYS13I, LYS142J, LYS143J, LYS145J, LYS181J, LYS193I, LYS19I, LYS210I, LYS223J, LYS235J, LYS237J, LYS23J, LYS256I, LYS268I, LYS273I, MET13J, MET174J, MET187J, MET220J, MET250I, PHE104J, PHE112J, PHE163I, PHE168I, PHE20I, PHE233J, PHE255I, PHE29I, PHE33I, PRO137I, PRO165I, PRO17J, PRO18J, PRO208J, PRO250J, PRO25I, PRO263I, PRO26I, PRO33J, SER150J, SER160I, SER171J, SER175I, SER184J, SER192J, SER206J, SER207J, SER208I, SER226J, SER244I, SER245J, SER251I, SER26J, SER276I, SER34J, SER9I, THR172J, THR179J, THR182J, THR186J, THR194J, THR227J, THR22I, THR236J, THR241I, THR249I, THR253I, THR254I, THR265I, THR267I, TRP148J, TRP169I, TRP173I, TRP176J, TRP177I, TRP271I, TYR107J, TYR111J, TYR131I, TYR136I, TYR198I, TYR199I, TYR232J, TYR239I, TYR247I, VAL132I, VAL14I, VAL173J, VAL196I, VAL204I, VAL207I, VAL217J, VAL240J, VAL264I, VAL32I, VAL32J, VAL36I, VAL8I
• I-V: ARG102I, ARG37I, ARG984V, ARG985V, ASN167I, ASN170I, ASN203I, ASN30I, ASN34I, ASP201I, ASP35I, GLN164I, GLU200I, GLU28I, GLU31I, GLU981V, GLU982V, GLU987V, GLY202I, GLY27I, GLY983V, HIS100I, HIS197I, HIS988V, LEU101I, LEU978V, LEU986V, LYS103I, LYS166I, PHE163I, PHE168I, PHE29I, PHE33I, PHE54I, PHE989V, PRO165I, PRO979V, SER980V, TRP169I, TYR199I
• J-Z: GLN1000Z, GLU84J, PRO1002Z, PRO82J
• J-V: ALA129J, ALA87J, ALA9J, ARG14J, ARG15J, ARG195J, ARG66J, ARG72J, ARG984V, ARG985V, ARG993V, ARG996V, ASN65J, ASN997V, ASP11J, ASP123J, ASP125J, ASP38J, ASP3J, ASP44J, ASP63J, ASP67J, ASP69J, ASP7J, ASP85J, CYS36J, CYS62J, CYS8J, GLN157J, GLN196J, GLN45J, GLN4J, GLU155J, GLU37J, GLU981V, GLU982V, GLU987V, GLY130J, GLY68J, GLY86J, GLY983V, HIS152J, HIS988V, ILE151J, LEU10J, LEU121J, LEU124J, LEU12J, LEU133J, LEU169J, LEU193J, LEU39J, LEU40J, LEU6J, LEU83J, LEU986V, LEU992V, LYS168J, LYS991V, LYS995V, LYS998V, MET13J, MET88J, PHE128J, PHE989V, PRO89J, PRO994V, SER171J, SER41J, SER42J, SER70J, SER980V, THR170J, THR172J, THR194J, THR990V, TRP122J, TYR120J, TYR64J, TYR71J, TYR79J, VAL131J, VAL153J, VAL154J, VAL156J, VAL43J