3A8Q

low-resolution crystal structure of the tiam2 phccex domain

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 93
  • Norm. En. per Res.: -3.9176
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	25.6383	-10.8094	14.8289	17	0	0	846	0	6	16
A-C	0.0	1.6171	-5.5271	-3.91	53	7	0	2892	1	10	27
A-D	0.0	0.0	-0.0004	-0.0004	2	0	0	1	0	2	2
B-C	0.0	-6.4009	-43.3785	-49.7794	34	9	0	1995	0	8	19
C-D	-65.4146	-70.5174	-228.402	-364.334	93	22	0	10218	4	28	36

Interface residues

• A-B: ALA529B, ARG530B, ARG531B, ARG632A, ARG639A, ASP629A, GLN643A, LEU642A, LYS514B, LYS532B, LYS581B, LYS582B, LYS635A, SER636A, SER640A, THR638A, TRP533B
• A-C: ALA655A, ALA670A, ARG632A, ARG632C, ARG639C, ASN667A, ASN681A, ASP629A, ASP646C, ASP648A, ASP648C, GLN637A, GLN643A, GLN643C, GLN658A, GLN658C, GLN674A, GLN677A, GLU628A, GLY626A, HIS625A, ILE645A, ILE671A, LEU633A, LEU641A, LEU657C, LEU659A, LYS624A, LYS627A, LYS635C, LYS644A, LYS650A, LYS650C, LYS652A, LYS652C, LYS653C, MET647A, MET647C, MET651A, MET651C, MET654A, MET654C, PHE685A, SER636A, SER636C, SER640A, SER649A, SER649C, SER660C, TRP678A, VAL661A, VAL661C, VAL662A
• A-D: ASP742A, GLY701D
• B-C: ALA561B, ALA622C, ARG563B, ARG632C, ASP570C, ASP741C, ASP742C, GLN535B, GLN599B, GLN643C, GLU549B, GLU569C, GLU628C, GLY626C, HIS625C, LEU511B, LEU620C, LEU633C, LYS532B, LYS534B, LYS582B, LYS623C, LYS624C, LYS627C, LYS644C, PHE512B, PHE621C, SER560B, THR550B, TRP510B, TRP533B, TRP537B, TYR536B, TYR551B
• C-D: ALA712C, ALA712D, ALA713C, ALA713D, ARG693C, ARG693D, ARG716C, ARG716D, ASN706C, ASN706D, CYS587C, CYS587D, GLN574C, GLN574D, GLN603C, GLN603D, GLU578C, GLU578D, GLU583C, GLU583D, GLU607C, GLU607D, GLU703C, GLU703D, GLY723C, GLY723D, GLY726C, GLY726D, HIS579C, HIS579D, HIS584C, HIS584D, LEU606C, LEU606D, LEU704C, LEU704D, LEU710C, LEU710D, LEU711C, LEU711D, LEU720C, LEU720D, LEU722C, LEU728C, LEU728D, LYS581C, LYS581D, LYS582C, LYS582D, LYS653C, LYS653D, LYS708C, LYS708D, LYS719C, LYS719D, PHE586C, PHE586D, PHE690C, PHE690D, PHE733C, PHE733D, PRO577C, PRO577D, PRO580C, PRO580D, PRO705C, PRO705D, PRO707C, PRO707D, PRO717C, PRO717D, SER575C, SER575D, SER709C, SER709D, SER715C, SER715D, SER729C, SER729D, SER731C, SER731D, THR604C, THR604D, THR714C, THR714D, VAL576C, VAL576D, VAL585C, VAL585D, VAL727C, VAL727D, VAL730C, VAL730D