3A77

the crystal structure of phosphorylated irf-3

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 57
  • Norm. En. per Res.: -4.3747
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-42.8785	-42.96	-163.518	-249.3565	57	7	0	4947	7	22	20
A-C	0.0	0.0	-2.9241	-2.9241	4	4	0	198	0	0	0
A-D	-25.1564	41.6673	-106.026	-89.5151	52	6	0	3499	0	4	11
B-C	-24.7479	40.5993	-98.8066	-82.9552	53	2	0	3236	0	4	11
C-D	-24.1977	-26.4833	-141.769	-192.4501	54	3	0	4435	6	22	14

Interface residues

• A-B: ALA410B, ARG262A, ARG285A, ASN190B, ASP314A, ASP328B, ASP414B, ASP420B, CYS267A, CYS289A, GLN279B, GLN354A, GLN356A, GLN413B, GLN422B, GLU310A, GLU350A, GLU417B, GLU426B, GLY269A, GLY278B, GLY287A, GLY323B, GLY349A, GLY418B, GLY423B, GLY425B, HIS263A, HIS288A, HIS290A, ILE330B, LEU196B, LEU265A, LEU268A, LEU286A, LEU415B, LYS193B, LYS313A, LYS315A, MET419B, PHE421B, PRO312A, PRO324B, PRO353A, PRO424B, SER259A, SER266A, SER351A, THR291A, THR331B, TRP352A, TYR260A, TYR292A, VAL264A, VAL311A, VAL327B, VAL416B
• A-C: LEU238A, LEU238C, THR237A, THR237C
• A-D: ARG194A, ARG194D, ASN397A, ASN397D, CYS222A, CYS222D, GLN217A, GLN217D, GLN218A, GLN218D, GLU200A, GLU200D, GLU201A, GLU201D, GLU203A, GLU203D, GLU224A, GLU224D, GLY199A, GLY199D, GLY225A, GLY225D, HIS399A, HIS399D, ILE220A, ILE220D, ILE395A, ILE395D, LEU226A, LEU226D, PHE204A, PHE204D, PRO198A, PRO198D, PRO223A, PRO223D, PRO242A, PRO242D, SER221A, SER221D, SER396A, SER396D, SER398A, SER398D, THR219A, THR219D, TRP241A, TRP241D, VAL197A, VAL197D, VAL243A, VAL243D
• B-C: ARG194B, ARG194C, ASN397B, ASN397C, CYS222B, CYS222C, GLN217C, GLN218B, GLN218C, GLU200B, GLU200C, GLU201B, GLU201C, GLU203B, GLU203C, GLU224B, GLU224C, GLY199B, GLY199C, GLY225B, GLY225C, GLY240C, HIS399B, HIS399C, ILE220B, ILE220C, ILE395B, ILE395C, LEU226B, LEU226C, PHE204B, PHE204C, PRO198B, PRO198C, PRO223B, PRO223C, PRO242B, PRO242C, SER221B, SER221C, SER396B, SER396C, SER398B, SER398C, THR219B, THR219C, THR237C, TRP241B, TRP241C, VAL197B, VAL197C, VAL243B, VAL243C
• C-D: ARG262C, ARG285C, ASN190D, ASP314C, ASP328D, ASP414D, ASP420D, CYS267C, CYS289C, GLN279D, GLN354C, GLN356C, GLN413D, GLN422D, GLU310C, GLU350C, GLU417D, GLU426D, GLY269C, GLY278D, GLY287C, GLY323D, GLY349C, GLY418D, GLY423D, GLY425D, HIS263C, HIS288C, HIS290C, LEU196D, LEU265C, LEU268C, LEU286C, LEU415D, LYS193D, LYS313C, MET419D, PHE421D, PRO312C, PRO324D, PRO353C, PRO424D, SER259C, SER266C, SER351C, THR291C, THR331D, TRP352C, TYR260C, TYR292C, VAL264C, VAL311C, VAL327D, VAL416D