3A2A

the structure of the carboxyl-terminal domain of the human voltage- gated proton channel hv1

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: A-D
  • Int. Res.: 55
  • Norm. En. per Res.: -2.4434
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-6.121	-7.4805	573.908	560.3065	82	12	22	12901	1	26	42
A-C	0.0	0.0	-0.0676	-0.0676	7	0	0	28	0	1	1
A-D	0.0	-11.7004	-122.684	-134.3844	55	1	4	4589	2	15	18
B-D	-4.8831	1.1842	-36.5148	-40.2137	23	11	0	1808	0	3	9
C-D	-6.1424	-8.4174	423.105	408.5452	82	15	22	12861	1	26	41

Interface residues

• A-B: ALA239A, ALA239B, ALA240A, ALA240B, ARG226A, ARG226B, ARG230A, ARG230B, ARG258A, ARG258B, ARG264A, ARG264B, ASN235A, ASN235B, ASN260A, ASN260B, CYS249A, CYS249B, GLN227A, GLN227B, GLN233A, GLN233B, GLN237A, GLN237B, GLN243A, GLN243B, GLN254A, GLN254B, GLN265A, GLN265B, GLU246A, GLU246B, GLU251A, GLU251B, GLU253A, GLU253B, GLU255A, GLU255B, GLU257A, GLU257B, HIS244A, HIS244B, HIS266A, HIS266B, ILE242A, ILE242B, ILE256A, ILE256B, LEU228A, LEU228B, LEU229A, LEU229B, LEU231A, LEU231B, LEU238A, LEU238B, LEU245A, LEU245B, LEU259A, LEU259B, LEU262A, LEU262B, LEU263A, LEU263B, LYS232A, LYS232B, LYS241A, LYS241B, LYS252A, LYS252B, LYS261A, LYS261B, MET234A, MET234B, PHE247A, PHE247B, SER248A, SER248B, SER250A, SER250B, VAL236A, VAL236B
• A-C: ARG258A, ARG264C, GLN233A, LEU231C, LEU238C, LEU262A, MET234C
• A-D: ALA239D, ALA240A, ALA240D, ARG226D, ARG230D, ARG258A, ARG258D, ASN235D, ASN260A, GLN227D, GLN233A, GLN233D, GLN237A, GLN237D, GLN243A, GLN243D, GLN254A, GLN254D, GLN265A, GLU246A, GLU246D, GLU251A, GLU251D, GLU255A, GLU255D, GLU257A, HIS244A, HIS244D, HIS266A, ILE242A, ILE242D, ILE256A, LEU228D, LEU229D, LEU231D, LEU238D, LEU245A, LEU245D, LEU259A, LEU262A, LEU263A, LYS232D, LYS241A, LYS241D, LYS252A, LYS252D, LYS261A, MET234D, PHE247A, PHE247D, SER248A, SER248D, SER250A, VAL236A, VAL236D
• B-D: ALA240D, ARG226D, ARG230D, ARG258B, ARG264B, ASN260B, CYS249B, GLN233D, GLN237D, GLN265B, GLU257B, HIS244D, HIS266B, ILE256B, LEU229D, LEU231D, LEU259B, LEU262B, LEU263B, LYS232D, LYS261B, MET234D, VAL236D
• C-D: ALA239C, ALA239D, ALA240C, ALA240D, ARG226C, ARG226D, ARG230C, ARG230D, ARG258C, ARG258D, ARG264C, ARG264D, ASN235C, ASN235D, ASN260C, ASN260D, CYS249C, CYS249D, GLN227C, GLN227D, GLN233C, GLN233D, GLN237C, GLN237D, GLN243C, GLN243D, GLN254C, GLN254D, GLN265C, GLN265D, GLU246C, GLU246D, GLU251C, GLU251D, GLU253C, GLU253D, GLU255C, GLU255D, GLU257C, GLU257D, HIS244C, HIS244D, HIS266C, HIS266D, ILE242C, ILE242D, ILE256C, ILE256D, LEU228C, LEU228D, LEU229C, LEU229D, LEU231C, LEU231D, LEU238C, LEU238D, LEU245C, LEU245D, LEU259C, LEU259D, LEU262C, LEU262D, LEU263C, LEU263D, LYS232C, LYS232D, LYS241C, LYS241D, LYS252C, LYS252D, LYS261C, LYS261D, MET234C, MET234D, PHE247C, PHE247D, SER248C, SER248D, SER250C, SER250D, VAL236C, VAL236D