2ZCL

crystal structure of human prostate specific antigen complexed with an activating antibody

• Total interactions analyzed: 3
• Total true interactions: 3
• Strongest Interaction:
  • Chains: P-H
  • Int. Res.: 71
  • Norm. En. per Res.: -3.3288
• Hub Node: P(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
P-L	-13.4176	-24.5318	-52.5891	-90.5385	32	2	0	1915	1	17	8
P-H	-43.276	-20.3604	-172.711	-236.3474	71	10	5	7255	2	15	6
L-H	-37.9698	-41.0594	-485.21	-564.2391	194	16	11	19691	2	15	18

Interface residues

• P-L: ARG235P, ASN92L, ASP240P, ASP27L, ASP28L, ASP30L, ASP94L, GLN128P, GLN90L, GLU93L, GLY29L, HIS233P, ILE238P, ILE2L, LEU123P, LYS178P, LYS236P, LYS239P, PHE27L, PHE49L, PRO124P, SER27L, SER31L, SER91L, THR125P, TRP237P, TYR234P, TYR32L, TYR96L, VAL232P, VAL243P, VAL27L
• P-H: ALA100H, ALA244P, ALA52H, ALA53H, ALA95H, ARG235P, ARG50H, ARG94H, ASN100H, ASN245P, ASP101H, ASP240P, ASP95P, ASP96H, ASP97P, ASP98P, GLN128P, GLU100H, GLU129P, GLY100H, GLY26H, GLY55H, GLY96P, GLY98H, HIS101P, HIS233P, HIS91P, ILE238P, ILE34H, ILE51H, LEU103P, LEU93P, LEU95P, LYS175P, LYS178P, LYS230P, LYS236P, MET180P, MET95P, PHE179P, PHE29H, PHE89P, PHE99H, PRO124P, PRO52H, PRO90P, PRO92P, SER100H, SER100P, SER54H, SER95P, SER99P, THR125P, THR177P, THR241P, THR28H, THR30H, THR31H, THR56H, THR57H, THR73H, TRP237P, TYR234P, TYR27H, TYR32H, TYR33H, TYR58H, TYR94P, TYR97H, VAL231P, VAL232P
• L-H: ALA100H, ALA125H, ALA130L, ALA168H, ALA50L, ALA51L, ALA55L, ALA93H, ALA95H, ARG213H, ARG38H, ARG50H, ARG94H, ASN100H, ASN137L, ASN138L, ASN161L, ASN210L, ASN34L, ASN35H, ASN53L, ASN92L, ASP101H, ASP130H, ASP165L, ASP167L, ASP170L, ASP1L, ASP28L, ASP30L, ASP94L, ASP96H, CYS128H, CYS134L, CYS140H, CYS214L, CYS88L, CYS92H, GLN105H, GLN124L, GLN171H, GLN37L, GLN38L, GLN39H, GLN42L, GLN43H, GLN6H, GLN89L, GLN90L, GLU100H, GLU123L, GLU213L, GLU46H, GLU61H, GLU93L, GLY100H, GLY100L, GLY101L, GLY104H, GLY106H, GLY128L, GLY129H, GLY129L, GLY139H, GLY158L, GLY162H, GLY29L, GLY41L, GLY44H, GLY49H, GLY98H, GLY99L, HIS164H, ILE117L, ILE210H, ILE48H, ILE48L, LEU124H, LEU125L, LEU136L, LEU138H, LEU141H, LEU160L, LEU170H, LEU177H, LEU179L, LEU181L, LEU45H, LEU46L, LEU47L, LYS143H, LYS169L, LYS207L, LYS208H, LYS209H, LYS45L, MET100H, MET175L, MET33L, MET37H, MET62H, PHE118L, PHE135L, PHE139L, PHE166H, PHE209L, PHE27L, PHE49L, PHE63H, PHE91H, PHE98L, PHE99H, PRO119L, PRO120H, PRO120L, PRO123H, PRO126H, PRO167H, PRO40L, PRO43L, PRO44L, PRO95L, SER100H, SER116L, SER121L, SER122L, SER127L, SER131L, SER135H, SER160H, SER161H, SER162L, SER172H, SER174L, SER176L, SER177L, SER178H, SER179H, SER180H, SER208L, SER31L, SER52L, SER56L, SER59H, SER60H, SER91L, THR114L, THR126L, THR131H, THR132H, THR137H, THR164L, THR165H, THR172L, THR176H, THR178L, THR180L, THR182H, THR57H, THR85L, THR97L, TRP103H, TRP154H, TRP163L, TRP188H, TRP35L, TRP36H, TRP47H, TYR102H, TYR122H, TYR173L, TYR186L, TYR32L, TYR33H, TYR36L, TYR58H, TYR86L, TYR87L, TYR96L, TYR97H, VAL115L, VAL121H, VAL127H, VAL132L, VAL133L, VAL136H, VAL142H, VAL159L, VAL163H, VAL169H, VAL181H, VAL211H, VAL27L, VAL89H