2Z80

crystal structure of the tlr1-tlr2 heterodimer induced by binding of a tri-acylated lipopeptide

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 217
  • Norm. En. per Res.: -2.1078
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-102.3527	-93.9031	-261.147	-457.4028	217	17	0	12840	13	99	78

Interface residues

• A-B: ALA338A, ALA338B, ALA80A, ALA80B, ARG155A, ARG155B, ARG230A, ARG230B, ARG257A, ARG257B, ARG286A, ARG286B, ARG319A, ARG32A, ASN110A, ASN110B, ASN130A, ASN130B, ASN199A, ASN199B, ASN258A, ASN258B, ASN287A, ASN287B, ASN311A, ASN311B, ASN33A, ASN33B, ASN61A, ASN61B, ASN86A, ASN86B, ASP106A, ASP106B, ASP160A, ASP160B, ASP185A, ASP185B, ASP231A, ASP231B, ASP233A, ASP233B, ASP235A, ASP235B, ASP314A, ASP31A, ASP31B, ASP58A, ASP58B, CYS226A, CYS226B, CYS340A, CYS340B, GLN152A, GLN152B, GLN187B, GLN209A, GLN209B, GLN288A, GLN288B, GLN335A, GLN335B, GLN79A, GLN79B, GLU103A, GLU103B, GLU177A, GLU177B, GLU178A, GLU178B, GLU180A, GLU180B, GLU225A, GLU225B, GLU228A, GLU228B, GLU264A, GLU264B, GLU281A, GLU281B, GLU283A, GLU283B, GLU334A, GLU334B, GLY133A, GLY133B, GLY336A, GLY336B, GLY342A, GLY342B, GLY344A, GLY344B, GLY38B, GLY41A, GLY41B, HIS104A, HIS104B, HIS202A, HIS202B, HIS206B, HIS210A, HIS210B, HIS309A, HIS309B, ILE153A, ILE153B, ILE204A, ILE204B, ILE261A, ILE261B, ILE35A, ILE35B, LEU105A, LEU105B, LEU126B, LEU129A, LEU129B, LEU132A, LEU132B, LEU151A, LEU151B, LEU154B, LEU176A, LEU176B, LEU179A, LEU179B, LEU203A, LEU203B, LEU234A, LEU234B, LEU289A, LEU289B, LEU308A, LEU57A, LEU59A, LEU59B, LEU83A, LEU83B, LYS150A, LYS150B, LYS208A, LYS208B, LYS253A, LYS253B, LYS260A, LYS260B, LYS290A, LYS290B, LYS305A, LYS305B, LYS339A, LYS339B, LYS345A, LYS37A, LYS37B, LYS55B, MET159A, MET159B, PHE128A, PHE128B, PHE175A, PHE175B, PHE237B, PRO312A, PRO312B, SER101B, SER108A, SER108B, SER125B, SER184A, SER184B, SER201A, SER201B, SER285A, SER285B, SER337A, SER337B, SER341A, SER341B, SER343A, SER343B, SER39A, SER39B, SER40A, SER40B, SER56B, SER60A, SER60B, SER85A, SER85B, THR127A, THR127B, THR149A, THR149B, THR236A, THR236B, THR255A, THR255B, THR262A, THR262B, THR310A, THR310B, THR84A, THR84B, TRP307A, TRP307B, TRP313A, TRP313B, TYR109A, TYR109B, TYR111B, VAL200B, VAL259A, VAL259B, VAL347A, VAL82A, VAL82B