2Z3Q

crystal structure of the il-15/il-15ra complex

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 64
  • Norm. En. per Res.: -6.2059
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-50.1505	-167.2951	-179.731	-397.1766	64	5	2	6531	11	43	20
A-C	0.0	-9.3772	-5.7897	-15.1669	13	0	0	363	0	5	7
A-D	-8.1291	-4.1408	-108.253	-120.5229	43	7	3	4289	0	5	5
B-C	0.0	-4.1514	-74.322	-78.4734	36	0	1	2691	0	6	6
B-D	0.0	0.0	-36.7317	-36.7317	42	4	0	2171	0	5	14
C-D	-49.0565	-159.6474	-177.943	-386.6468	67	6	2	6815	10	43	20

Interface residues

• A-B: ALA23A, ALA37B, ALA68B, ARG24B, ARG26B, ARG35B, ARG65B, ASP22A, ASP66B, CYS29B, CYS42A, CYS63B, CYS85A, CYS88A, GLN48A, GLN72B, GLU44B, GLU46A, GLU53A, GLU87A, GLU89A, GLU90A, GLU92A, GLU93A, GLY38B, GLY55A, HIS20A, HIS71B, ILE21A, ILE50A, ILE64B, ILE96A, LEU25A, LEU42B, LEU44A, LEU45A, LEU47A, LEU52A, LEU61B, LEU69B, LEU91A, LYS34B, LYS36B, LYS41A, LYS62B, LYS86A, LYS94A, MET19A, PHE33B, PHE43A, PHE99A, PRO59B, PRO67B, SER40B, SER41B, SER54A, SER60B, THR24A, THR27A, THR39B, THR43B, TYR26A, VAL49A, VAL70B
• A-C: ASP56A, ASP56C, GLN17A, GLN17C, HIS20A, HIS20C, LEU15A, LEU15C, MET19A, MET19C, SER18A, SER18C, SER58A
• A-D: ALA-2D, ALA57A, ARG24D, ASN52D, ASN65A, ASN71A, ASP56A, ASP61A, CYS45D, GLN48A, GLU44D, GLU53A, GLU64A, GLY55A, HIS60A, ILE-1D, ILE1D, ILE50A, ILE59A, ILE67A, ILE68A, LEU21D, LEU44A, LEU45A, LEU47A, LEU47D, LEU52A, LEU66A, LYS49D, MET-3D, SER0D, SER18D, SER20D, SER23D, SER51A, SER54A, SER58A, THR2D, THR62A, TYR22D, VAL46D, VAL49A, VAL63A
• B-C: ALA-2B, ALA57C, ARG24B, ASP56C, ASP61C, CYS45B, GLN48C, GLU44B, GLU53C, GLU64C, GLY55C, HIS60C, ILE-1B, ILE1B, ILE50C, ILE59C, ILE67C, ILE68C, LEU21B, LEU45C, LEU47B, LEU52C, LYS49B, MET19C, SER0B, SER18B, SER20B, SER23B, SER51C, SER54C, SER58C, THR2B, TYR22B, VAL46B, VAL49C, VAL63C
• B-D: ALA-2B, ALA-2D, ALA50B, ALA50D, ARG24B, ASN48B, ASN48D, ASN52B, ASN52D, GLU44B, GLY38B, GLY38D, HIS55B, HIS55D, ILE-1D, LEU42B, LEU42D, LEU47B, LEU47D, LEU61B, LEU61D, LYS49B, LYS49D, PRO59B, PRO59D, SER40B, SER40D, SER41B, SER60B, SER60D, THR39B, THR39D, THR43B, THR51B, THR51D, THR57B, THR57D, THR58B, THR58D, TYR22D, VAL46B, VAL46D
• C-D: ALA23C, ALA37D, ALA68D, ARG24D, ARG26D, ARG35D, ARG65D, ARG73D, ASP22C, ASP66D, CYS29D, CYS42C, CYS63D, CYS85C, CYS88C, GLN48C, GLN72D, GLU44D, GLU46C, GLU53C, GLU87C, GLU89C, GLU90C, GLU92C, GLU93C, GLY38D, GLY55C, GLY84C, HIS20C, HIS71D, ILE21C, ILE50C, ILE64D, ILE96C, LEU25C, LEU42D, LEU44C, LEU45C, LEU47C, LEU52C, LEU61D, LEU69D, LEU91C, LYS17D, LYS34D, LYS36D, LYS41C, LYS62D, LYS86C, LYS94C, MET19C, PHE33D, PHE43C, PRO59D, PRO67D, SER40D, SER41D, SER54C, SER60D, THR24C, THR27C, THR39D, THR43D, THR58D, TYR26C, VAL49C, VAL70D