2YJF

oligomeric assembly of actin bound to mrtf-a

• Total interactions analyzed: 15
• Total true interactions: 12
• Strongest Interaction:
  • Chains: A-M
  • Int. Res.: 112
  • Norm. En. per Res.: -2.9822
• Hub Node: B(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	8.8339	-22.8677	-14.0338	36	0	2	1297	0	29	24
A-D	0.0	-27.916	-13.8303	-41.7463	22	3	0	861	2	14	11
A-M	-29.5862	-19.7708	-284.647	-334.0041	112	24	10	12545	1	25	27
B-C	-2.8275	-5.8484	-45.0459	-53.7218	47	2	3	2233	2	31	16
B-D	0.0	0.0	-0.0052	-0.0052	3	0	0	4	0	0	0
B-E	0.0	0.0	-5.5409	-5.5409	16	0	0	354	0	16	9
B-M	-50.9996	-35.379	-331.928	-418.3066	159	23	13	14892	2	49	55
C-D	0.0	0.0	-1.3354	-1.3354	10	0	0	134	0	6	2
C-E	0.0	0.0	-0.1931	-0.1931	5	0	0	26	0	0	0
C-M	-29.4237	-4.362	-235.746	-269.5316	111	33	12	10850	0	36	33
D-M	-29.5955	8.2261	-155.197	-176.5664	75	11	4	7256	0	24	15
E-M	-5.159	26.2591	-122.823	-101.7229	64	14	5	6522	0	11	13

Interface residues

• A-B: ALA19B, ALA26B, ALA29B, ARG210B, ARG28B, ARG290A, ASN92B, ASP24B, ASP286A, ASP288A, ASP292A, CYS285A, GLU167A, GLU214B, GLU334B, GLU93B, HIS88B, ILE287A, ILE289A, LEU16B, LYS18B, LYS215B, LYS291A, LYS336B, MET283A, MET305B, PHE31B, PRO27B, PRO322A, PRO333B, SER323A, THR149A, THR324A, TYR166A, TYR337B, VAL30B
• A-D: ALA114A, ALA26D, ALA29D, ARG116A, ARG28D, ASN111A, ASN115A, ASP24D, ASP25D, GLU117A, GLY23D, HIS371A, LEU110A, LYS113A, LYS118A, PHE21D, PRO112A, PRO172A, PRO27D, PRO367A, SER368A, VAL370A
• A-M: ALA100M, ALA101M, ALA144A, ALA170A, ALA174A, ALA22A, ALA26A, ALA347A, ARG106M, ARG147A, ARG290A, ARG372A, ARG70M, ARG81M, ARG82M, ARG84M, ASN111A, ASN296A, ASN72M, ASP24A, ASP25A, ASP286A, ASP288A, CYS285A, CYS374A, GLN353A, GLN354A, GLN75M, GLN79M, GLN80M, GLN90M, GLU104M, GLU107M, GLU167A, GLU334A, GLU69M, GLU85M, GLU86M, GLY146A, GLY168A, GLY23A, GLY342A, GLY343A, GLY65M, GLY91M, HIS103M, HIS173A, HIS371A, ILE165A, ILE175A, ILE287A, ILE289A, ILE330A, ILE341A, ILE345A, ILE92M, LEU110A, LEU140A, LEU142A, LEU171A, LEU293A, LEU346A, LEU349A, LEU67M, LEU74M, LEU76M, LEU78M, LEU87M, LEU96M, LYS113A, LYS284A, LYS373A, LYS71M, LYS77M, LYS97M, MET176A, MET355A, MET93M, PHE102M, PHE21A, PHE352A, PHE375A, PRO112A, PRO164A, PRO172A, PRO332A, PRO333A, PRO64M, PRO94M, PRO95M, PRO99M, SER145A, SER344A, SER348A, SER350A, SER66M, SER68M, SER98M, THR148A, THR149A, THR351A, THR83M, TRP340A, TYR133A, TYR143A, TYR166A, TYR169A, VAL139A, VAL370A, VAL73M, VAL88M, VAL9A
• B-C: ALA19C, ALA26C, ALA29C, ALA321B, ALA58C, ARG28C, ARG290B, ARG95C, ASN92C, ASP24C, ASP25C, ASP286B, ASP288B, ASP56C, CYS285B, GLU214C, GLU334C, GLU57C, GLU93C, ILE287B, ILE289B, ILE341C, LEU16C, LEU94C, LYS18C, LYS215C, LYS284B, LYS336C, MET283B, MET305C, MET325B, PHE21C, PHE31C, PRO27C, PRO322B, PRO333C, SER323B, THR324B, TRP340C, TYR166B, TYR279B, TYR294B, TYR337C, TYR91C, VAL17C, VAL30C, VAL54C
• B-D: ASP292D, SER350B, TYR166D
• B-E: ALA114B, ALA26E, ARG177B, ARG28E, ASN111B, ASN115B, ASP179B, ASP24E, ASP25E, GLU117B, GLY23E, ILE75B, LEU110B, LYS113B, PRO112B, PRO333E
• B-M: ALA112M, ALA114B, ALA129M, ALA142M, ALA144B, ALA148M, ALA170B, ALA174B, ALA22B, ALA26B, ALA310B, ALA331B, ALA347B, ARG106M, ARG111M, ARG113M, ARG116B, ARG120M, ARG123M, ARG125M, ARG128M, ARG133M, ARG147B, ARG177B, ARG254B, ARG290B, ARG335B, ARG82M, ASN111B, ASN115B, ASP116M, ASP24B, ASP25B, ASP286B, ASP288B, CYS217B, CYS285B, CYS374B, GLN147M, GLN150M, GLN353B, GLN354B, GLN79M, GLN80M, GLN90M, GLU104M, GLU107M, GLU110M, GLU115M, GLU127M, GLU130M, GLU138M, GLU143M, GLU167B, GLU214B, GLU241B, GLU334B, GLU86M, GLY146B, GLY168B, GLY23B, GLY302B, GLY308B, GLY342B, GLY343B, GLY91M, HIS135M, HIS173B, HIS371B, ILE122M, ILE136B, ILE136M, ILE165B, ILE175B, ILE248B, ILE287B, ILE289B, ILE309B, ILE341B, ILE345B, ILE75B, ILE92M, LEU110B, LEU118M, LEU131M, LEU137M, LEU140B, LEU142B, LEU146M, LEU151M, LEU171B, LEU216B, LEU293B, LEU346B, LEU349B, LEU76M, LEU87M, LYS113B, LYS119M, LYS121M, LYS149M, LYS152M, LYS213B, LYS215B, LYS238B, LYS284B, LYS336B, LYS373B, LYS77M, MET134M, MET176B, MET305B, MET355B, MET93M, PHE21B, PHE352B, PHE375B, PRO109B, PRO112B, PRO126M, PRO144M, PRO164B, PRO172B, PRO307B, PRO332B, PRO333B, PRO94M, PRO95M, SER108M, SER124M, SER145B, SER145M, SER239B, SER344B, SER348B, SER350B, SER89M, THR114M, THR140M, THR148B, THR149B, THR304B, THR351B, THR83M, TRP340B, TYR117M, TYR133B, TYR143B, TYR166B, TYR169B, TYR218B, TYR240B, TYR306B, TYR337B, VAL132M, VAL139B, VAL247B, VAL88M, VAL9B
• C-D: ARG372D, ASP244C, CYS374D, GLN246C, GLU241C, GLY245C, ILE369D, LYS373D, PRO243C, SER368D
• C-E: GLU167E, GLY146C, SER350C, THR351E, TYR166E
• C-M: ALA144C, ALA156M, ALA159M, ALA167M, ALA170C, ALA174C, ALA22C, ALA26C, ALA331C, ALA347C, ARG120M, ARG133M, ARG147C, ARG155M, ARG169M, ARG172M, ARG254C, ARG335C, ASN163M, ASN179M, ASP160M, ASP161M, ASP24C, ASP25C, ASP286C, ASP288C, CYS217C, CYS285C, CYS374C, GLN168M, GLN353C, GLN354C, GLU130M, GLU138M, GLU139M, GLU164M, GLU167C, GLU171M, GLU174M, GLU214C, GLU241C, GLU334C, GLY146C, GLY168C, GLY23C, GLY308C, GLY342C, HIS135M, HIS173C, ILE136C, ILE136M, ILE165C, ILE166M, ILE180M, ILE287C, ILE289C, ILE341C, ILE345C, LEU131M, LEU137M, LEU140C, LEU142C, LEU151M, LEU158M, LEU162M, LEU171C, LEU175M, LEU181M, LEU216C, LEU293C, LEU346C, LEU349C, LYS165M, LYS178M, LYS215C, LYS284C, LYS336C, LYS373C, MET134M, MET173M, MET305C, MET355C, PHE21C, PHE352C, PHE375C, PRO164C, PRO170M, PRO172C, PRO182M, PRO27C, PRO307C, PRO332C, PRO333C, SER145C, SER344C, SER348C, SER350C, THR140M, THR148C, THR149C, THR351C, TRP340C, TYR133C, TYR143C, TYR166C, TYR169C, TYR218C, TYR306C, TYR337C, VAL132M, VAL139C
• D-M: ALA100M, ALA101M, ALA112M, ALA144D, ALA22D, ALA26D, ALA347D, ALA7D, ARG106M, ARG111M, ARG113M, ARG120M, ARG123M, ARG147D, ASP116M, ASP24D, ASP25D, ASP288D, CYS374D, GLN105M, GLN353D, GLN354D, GLU104M, GLU107M, GLU110M, GLU115M, GLU167D, GLU334D, GLY146D, GLY168D, GLY23D, GLY342D, HIS103M, ILE330D, ILE341D, ILE345D, LEU109M, LEU140D, LEU142D, LEU346D, LEU349D, LEU96M, LYS119M, LYS373D, LYS97M, MET355D, PHE102M, PHE21D, PHE352D, PHE375D, PRO27D, PRO332D, PRO333D, PRO95M, PRO99M, SER108M, SER145D, SER338D, SER344D, SER348D, SER350D, SER98M, THR114M, THR148D, THR149D, THR351D, THR6D, TRP340D, TYR117M, TYR133D, TYR143D, TYR166D, TYR169D, TYR337D, VAL139D
• E-M: ALA142M, ALA144E, ALA148M, ALA156M, ALA159M, ALA22E, ALA26E, ALA347E, ARG147E, ARG155M, ARG157M, ASN163M, ASP160M, ASP161M, ASP24E, ASP25E, GLN147M, GLN150M, GLN353E, GLN354E, GLU139M, GLU143M, GLU164M, GLU167E, GLU334E, GLY146E, GLY168E, GLY23E, GLY342E, GLY343E, ILE341E, ILE345E, LEU140E, LEU142E, LEU146M, LEU151M, LEU153M, LEU158M, LEU346E, LEU349E, LYS149M, LYS152M, LYS154M, MET355E, PHE21E, PHE352E, PRO144M, SER141M, SER145E, SER145M, SER344E, SER348E, SER350E, THR140M, THR148E, THR149E, THR351E, THR6E, TRP340E, TYR133E, TYR143E, TYR166E, TYR169E, VAL139E