2Y22

human alphab-crystallin domain (residues 67-157)

• Total interactions analyzed: 15
• Total true interactions: 9
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 64
  • Norm. En. per Res.: -5.3138
• Hub Node: B(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-100.0464	-53.1053	-173.715	-326.8667	63	11	2	6122	8	64	61
B-C	0.0	0.0	-0.0499	-0.0499	2	0	0	18	0	5	4
B-D	0.0	0.0	-2.5971	-2.5971	19	0	0	365	0	32	35
B-E	0.0	0.0	-15.5398	-15.5398	22	4	1	677	0	7	8
B-F	0.0	0.0	-0.1018	-0.1018	6	0	0	27	0	3	4
C-D	-106.8299	-44.6982	-188.556	-340.0841	64	13	2	6388	8	64	62
C-E	0.0	0.0	-0.1478	-0.1478	5	0	0	46	0	2	1
D-E	0.0	8.4683	-3.0871	5.3812	18	0	0	354	0	6	10
E-F	-83.1702	-0.7069	-166.772	-250.649	62	13	2	5986	4	63	58

Interface residues

• A-B: ARG107A, ARG107B, ARG116A, ARG116B, ARG120A, ARG120B, ARG123A, ARG123B, ASN78A, ASN78B, ASP109A, ASP109B, GLN108A, GLN108B, GLU106A, GLU106B, GLU110A, GLU110B, GLU117A, GLU117B, GLU67A, GLU99A, GLU99B, GLY102A, GLY102B, GLY112A, GLY112B, HIS101A, HIS101B, HIS104A, HIS104B, HIS111A, HIS111B, HIS119A, HIS119B, HIS83A, HIS83B, ILE114A, ILE114B, ILE98A, ILE98B, LEU79A, LEU79B, LYS103A, LYS103B, LYS121A, LYS121B, PHE113A, PHE113B, PHE118A, PHE118B, PHE84A, PHE84B, SER115A, SER115B, TYR122A, TYR122B, VAL100A, VAL100B, VAL77A, VAL77B, VAL97A, VAL97B
• B-C: GLU106C, GLU87B
• B-D: ASP96D, GLU105B, GLU117B, GLU87B, GLU88B, GLU99D, GLY95D, HIS101B, HIS119D, LEU89B, LEU94D, LYS103B, LYS90B, LYS90D, LYS92B, LYS92D, VAL91D, VAL93D, VAL97D
• B-E: ALA126E, ARG123E, ASN78E, ASP127E, ASP129B, ASP73E, ASP96E, GLY95B, ILE124E, LEU131B, LEU94B, LYS92B, PHE75E, PRO125E, PRO130B, SER76E, THR132B, TYR122E, VAL128E, VAL77E, VAL91B, VAL93B
• B-F: ASP96B, GLU110F, GLY95B, HIS111F, LEU94B, PRO130B
• C-D: ARG107C, ARG107D, ARG116C, ARG116D, ARG120C, ARG120D, ARG123C, ARG123D, ARG69D, ASN78C, ASN78D, ASP109C, ASP109D, GLN108C, GLN108D, GLU105D, GLU106C, GLU106D, GLU110C, GLU110D, GLU117C, GLU117D, GLU99C, GLU99D, GLY102C, GLY102D, GLY112C, GLY112D, HIS101C, HIS101D, HIS104C, HIS104D, HIS111C, HIS111D, HIS119C, HIS119D, HIS83C, HIS83D, ILE114C, ILE114D, ILE98C, ILE98D, LEU79C, LEU79D, LYS103C, LYS103D, LYS121C, LYS121D, PHE113C, PHE113D, PHE118C, PHE118D, PHE84C, PHE84D, SER115C, SER115D, TYR122C, TYR122D, VAL100C, VAL100D, VAL77C, VAL77D, VAL97C, VAL97D
• C-E: ARG74E, ASP73E, GLN108C, PHE113C, PRO148E
• D-E: ALA126D, ARG74E, ASN146E, ASN78E, ASP127D, ASP140E, ASP73D, ASP73E, ASP96D, LYS72D, PRO125D, SER136E, SER138E, SER139E, SER76E, THR144E, VAL142E, VAL97D
• E-F: ARG107E, ARG107F, ARG116E, ARG116F, ARG120E, ARG120F, ARG123E, ARG123F, ASN78E, ASN78F, ASP109E, ASP109F, GLN108E, GLN108F, GLU105E, GLU106E, GLU106F, GLU110E, GLU110F, GLU117E, GLU117F, GLU99E, GLU99F, GLY102E, GLY102F, GLY112E, GLY112F, HIS101E, HIS101F, HIS104E, HIS104F, HIS111E, HIS111F, HIS119E, HIS119F, HIS83E, HIS83F, ILE114E, ILE114F, ILE98E, ILE98F, LEU79F, LYS103E, LYS103F, LYS121E, LYS121F, PHE113E, PHE113F, PHE118E, PHE118F, PHE84E, PHE84F, SER115E, SER115F, TYR122E, TYR122F, VAL100E, VAL100F, VAL77E, VAL77F, VAL97E, VAL97F