2Y21
the mechanisms of hamp-mediated signaling in transmembrane receptors - the a291v mutant
Total interactions analyzed 66
Total true interactions 25
Strongest Interaction Chains K-L
Int. Res. 76
Norm. En. per Res. -4.0211
Hub Node A(5)
Click on the Nodes or Edges in the network to see the details
Weak Strong
Width of edge <-> No. of inter. res.
All Interactions
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Chains Hydro. Bond Ener. (kJ/mol) Elec. Ener. (kJ/mol) VDW. Ener. (kJ/mol) Tot. Stab. Ener. (kJ/mol) #int. res. # Short cont. #Hydr. int. #VDW pairs #salt bridges #Pot. fav. elec. int #Pot. unfav. elec. int int. res.
A-B -19.3826 -70.2586 -207.932 -297.5731 78 5 17 9943 4 24 15
A-C 0.0 34.5642 -16.549 18.0152 13 1 1 814 0 8 11
A-D 0.0 -17.4601 -7.0288 -24.489 24 7 1 1455 0 12 9
A-J 0.0 0.0 -1.0976 -1.0976 14 0 0 186 0 4 4
A-L 0.0 -0.4282 -10.5788 -11.007 17 1 0 804 0 11 15
B-C -9.0862 -24.732 -32.2556 -66.0738 29 5 1 2152 1 17 10
B-D 0.0 0.0 -10.7028 -10.7028 16 0 0 720 0 0 3
B-H 0.0 0.0 -0.003 -0.003 2 0 0 4 0 0 0
C-D -12.8955 -71.4407 -197.062 -281.3983 78 7 16 9683 4 22 13
C-F 0.0 0.0 -0.0159 -0.0159 2 0 0 12 0 0 1
C-H -7.8401 14.0882 31.6183 37.8664 41 28 0 1754 0 23 22
C-J 0.0 0.0 -0.288 -0.288 8 0 0 76 0 1 1
D-J 0.0 -5.4574 -27.861 -33.3184 24 4 0 1620 0 9 6
E-F -13.8878 -73.9646 -208.659 -296.5114 82 9 17 10032 4 22 16
E-G -5.7091 -18.9751 -24.1119 -48.796 27 6 1 1892 0 15 9
E-H 0.0 35.7381 -17.0736 18.6645 14 1 1 815 0 8 11
F-G 0.0 0.0 -3.5215 -3.5215 8 0 0 384 0 0 2
F-H -6.77 -19.5877 -29.4063 -55.764 28 9 1 1966 0 15 9
G-H -7.9284 -71.1415 -201.801 -280.8709 75 9 17 9837 4 22 14
I-J -14.2657 -74.5604 -210.533 -299.3591 80 8 16 10225 4 25 14
I-K 0.0 -17.1165 -7.5857 -24.7022 21 6 1 1335 0 11 9
I-L 0.0 0.0 -2.9922 -2.9922 9 0 0 328 0 0 2
J-K 0.0 33.4797 -15.0398 18.4399 15 2 1 795 0 7 11
J-L -16.0695 -26.8004 -44.4198 -87.2896 32 5 1 2455 1 16 11
K-L -19.8169 -76.1853 -209.605 -305.6071 76 8 17 10069 4 22 14