2XVT

structure of the extracellular domain of human ramp2

• Total interactions analyzed: 15
• Total true interactions: 10
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 62
  • Norm. En. per Res.: -3.7594
• Hub Node: B(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-34.3857	6.2988	-179.527	-207.6139	62	7	3	7016	2	12	8
A-C	-40.5551	-2.5458	-189.98	-233.081	62	4	4	7233	2	10	7
B-C	-32.7882	-8.4276	-169.7	-210.9157	62	4	4	6881	2	12	8
B-D	-16.8456	-86.2764	-205.784	-308.906	83	4	1	7777	9	32	43
B-F	0.0	5.5709	-0.1247	5.4462	6	0	0	23	0	2	4
C-D	0.0	0.0	-0.0351	-0.0351	5	0	0	7	0	2	3
C-F	0.0	83.4884	-15.6321	67.8563	20	0	0	511	0	10	14
D-E	-19.4907	-8.0495	-152.596	-180.1363	57	4	2	6231	2	11	8
D-F	-28.5085	6.5206	-175.296	-197.2839	62	5	3	7085	2	12	9
E-F	-43.6513	-2.4696	-187.217	-233.3379	63	5	4	7316	2	12	7

Interface residues

• A-B: ALA104B, ALA116B, ALA129A, ALA87A, ARG118B, ARG91A, ARG97A, ARG97B, ASN113B, ASN130A, ASN60B, ASP108B, ASP85A, ASP98A, CYS131A, CYS84A, GLN125A, GLN135A, GLN66B, GLU101A, GLU117A, GLU117B, GLU122B, GLU62B, GLY110B, HIS124A, HIS127A, ILE119B, ILE120A, ILE120B, ILE126A, ILE89A, LEU109B, LEU115B, LEU133A, LEU96A, MET76A, MET88A, PHE107B, PHE111A, PHE111B, PHE121A, PHE121B, PHE128A, PRO112A, PRO112B, PRO114B, PRO92A, SER132A, SER90A, SER94A, THR123A, THR63B, THR95A, TRP69B, TRP83A, TRP86A, TYR61B, TYR72A, TYR93A, VAL134A, VAL65B
• A-C: ALA104A, ALA116A, ALA129C, ALA64A, ALA87C, ARG118A, ARG91C, ARG97A, ARG97C, ASN113A, ASN130C, ASN60A, ASP108A, ASP85C, ASP98C, CYS131C, CYS84C, GLN125C, GLN135C, GLN66A, GLU117A, GLU117C, GLU122A, GLU62A, GLY110A, HIS124C, HIS127C, ILE119A, ILE120A, ILE120C, ILE89C, LEU109A, LEU115A, LEU133C, LEU96C, LYS59A, MET76C, MET88C, PHE107A, PHE111A, PHE111C, PHE121A, PHE121C, PHE128C, PRO112A, PRO112C, PRO114A, PRO136C, PRO92C, SER132C, SER90C, SER94C, THR123C, THR63A, TRP69A, TRP83C, TRP86C, TYR61A, TYR72C, TYR93C, VAL134C, VAL65A
• B-C: ALA104C, ALA116C, ALA129B, ALA64C, ALA87B, ARG118C, ARG91B, ARG97B, ARG97C, ASN113C, ASN130B, ASN60C, ASP108C, ASP85B, ASP98B, CYS131B, CYS84B, GLN125B, GLN135B, GLN66C, GLU101B, GLU117B, GLU117C, GLU122C, GLU62C, GLY110C, HIS124B, HIS127B, ILE119C, ILE120B, ILE120C, ILE89B, LEU109C, LEU115C, LEU133B, LEU96B, MET76B, MET88B, PHE107C, PHE111B, PHE111C, PHE121B, PHE121C, PHE128B, PRO112B, PRO112C, PRO114C, PRO92B, SER132B, SER90B, SER94B, THR123B, THR63C, THR95B, TRP69C, TRP83B, TRP86B, TYR61C, TYR72B, TYR93B, VAL134B, VAL65C
• B-D: ALA104B, ALA104D, ALA64B, ALA64D, ALA87B, ALA87D, ARG91B, ARG91D, ARG97B, ARG97D, ASN70B, ASN70D, ASP108B, ASP108D, ASP74B, ASP74D, ASP77B, ASP82B, ASP82D, ASP85B, ASP85D, ASP98B, ASP98D, CYS68B, CYS68D, CYS99B, CYS99D, GLN75B, GLN75D, GLU101B, GLU101D, GLU105B, GLU105D, HIS102B, HIS102D, HIS71B, HIS71D, ILE79B, ILE79D, ILE89B, ILE89D, LEU100B, LEU100D, LEU106B, LEU106D, LEU96B, LEU96D, LYS59D, LYS73B, LYS73D, LYS81B, LYS81D, MET76B, MET76D, MET88B, MET88D, PHE103B, PHE103D, PHE111B, PHE111D, PHE67B, PHE67D, PRO78B, PRO78D, PRO92B, PRO92D, SER90B, SER90D, SER94B, SER94D, THR57D, THR95B, THR95D, TRP69B, TRP69D, TRP83B, TRP83D, TYR72B, TYR72D, TYR93B, TYR93D, VAL58B, VAL58D
• B-F: ASP108F, ASP98B, GLU101B, GLY110F, LEU109F, SER94B
• C-D: ASP108C, ASP98D, GLU101D, GLY110C, LEU109C
• C-F: ALA104C, ALA104F, ASP108C, ASP108F, GLU101C, GLU101F, GLU105C, GLU105F, GLY110C, GLY110F, HIS102C, HIS102F, LEU106C, LEU106F, LEU109C, LEU109F, PHE111C, PHE111F, PRO112C, PRO112F
• D-E: ALA104D, ALA116D, ALA129E, ALA87E, ARG118D, ARG91E, ARG97D, ARG97E, ASN113D, ASN130E, ASN60D, ASP108D, ASP85E, ASP98E, CYS131E, CYS84E, GLN125E, GLN66D, GLU117D, GLU117E, GLU122D, GLU62D, GLY110D, HIS124E, HIS127E, ILE119D, ILE120D, ILE120E, ILE89E, LEU109D, LEU115D, LEU133E, LEU96E, MET76E, MET88E, PHE107D, PHE111D, PHE111E, PHE121D, PHE121E, PHE128E, PRO112D, PRO112E, PRO114D, PRO92E, SER132E, SER90E, SER94E, THR123E, THR95E, TRP69D, TRP83E, TRP86E, TYR61D, TYR72E, TYR93E, VAL65D
• D-F: ALA104F, ALA116F, ALA129D, ALA87D, ARG118F, ARG91D, ARG97D, ARG97F, ASN113F, ASN130D, ASN60F, ASN70F, ASP108F, ASP85D, ASP98D, CYS131D, CYS84D, GLN125D, GLN135D, GLN66F, GLU101D, GLU117D, GLU117F, GLU122F, GLU62F, GLY110F, HIS124D, HIS127D, ILE119F, ILE120D, ILE120F, ILE126D, ILE89D, LEU109F, LEU115F, LEU133D, LEU96D, MET76D, MET88D, PHE107F, PHE111D, PHE111F, PHE121D, PHE121F, PHE128D, PRO112D, PRO112F, PRO114F, PRO92D, SER132D, SER90D, SER94D, THR123D, THR63F, TRP69F, TRP83D, TRP86D, TYR61F, TYR72D, TYR93D, VAL134D, VAL65F
• E-F: ALA104E, ALA116E, ALA129F, ALA64E, ALA87F, ARG118E, ARG91F, ARG97E, ARG97F, ASN113E, ASN130F, ASN60E, ASP108E, ASP85F, ASP98F, CYS131F, CYS84F, GLN125F, GLN135F, GLN66E, GLU117E, GLU117F, GLU122E, GLU62E, GLY110E, HIS124F, HIS127F, ILE119E, ILE120E, ILE120F, ILE89F, LEU109E, LEU115E, LEU133F, LEU96F, MET76F, MET88F, PHE107E, PHE111E, PHE111F, PHE121E, PHE121F, PHE128F, PHE67E, PRO112E, PRO112F, PRO114E, PRO136F, PRO92F, SER132F, SER90F, SER94F, THR123F, THR63E, THR95F, TRP69E, TRP83F, TRP86F, TYR61E, TYR72F, TYR93F, VAL134F, VAL65E