2XTG

trna tranlocation on the 70s ribosome: the pre- translocational translocation intermediate ti(pre)

• Total interactions analyzed: 528
• Total true interactions: 31
• Strongest Interaction:
  • Chains: E-R
  • Int. Res.: 15
  • Norm. En. per Res.: -3.6396
• Hub Node: E(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
0-8	0.0	0.0	-0.0173	-0.0173	4	0	0	17	0	2	1
0-Q	0.0	4.2477	-48.601	-44.3533	26	9	1	2753	0	3	12
0-S	0.0	-4.9045	-1.4199	-6.3244	14	0	0	203	0	8	11
2-X	-6.2603	-15.6235	-109.501	-131.3848	47	2	1	4777	2	9	12
4-G	-3.0081	0.1643	-165.797	-168.6408	87	27	3	9262	0	27	23
5-R	0.0	3.3691	-50.8094	-47.4403	39	16	3	3323	1	7	15
5-U	0.0	0.0	-1.5954	-1.5954	11	0	0	281	0	0	6
5-W	-3.0956	30.4864	-79.9829	-52.592	50	21	3	4340	0	13	19
6-8	0.0	0.0	-21.5186	-21.5186	19	6	0	1097	0	4	2
7-F	0.0	0.0	-0.0063	-0.0063	3	0	0	5	0	0	0
7-W	0.0	0.0	-0.0004	-0.0004	2	0	0	1	0	0	1
7-X	0.0	0.0	-4.4404	-4.4404	11	0	0	375	0	2	6
8-P	-13.5873	40.3326	-137.412	-110.6667	59	17	0	7214	2	16	59
9-H	0.0	0.0	-0.0933	-0.0933	7	0	0	36	0	1	2
9-Q	0.0	0.0	-0.9779	-0.9779	6	0	0	111	0	1	2
E-N	0.0	0.0	-38.0383	-38.0383	13	2	0	1354	0	0	2
E-O	0.0	4.2831	-22.9584	-18.6753	15	0	0	952	0	7	8
E-R	-6.0989	0.8556	-49.3502	-54.5935	15	11	0	2452	0	1	12
E-T	0.0	-29.0856	-101.946	-131.0316	71	1	4	5833	0	18	17
F-P	0.0	6.3826	-93.6227	-87.2401	43	16	0	4556	0	18	20
F-U	0.0	0.0	-1.8684	-1.8684	9	0	0	369	0	0	2
K-L	0.0	10.8618	-16.0555	-5.1937	25	0	0	1133	0	11	11
K-Z	0.0	7.8356	-6.2622	1.5733	7	8	0	435	0	1	4
N-U	-14.057	-6.2004	-96.2434	-116.5008	49	12	1	5310	0	9	24
N-V	0.0	1.9181	-11.0818	-9.1637	15	7	0	928	0	1	5
O-T	-26.1459	10.6591	-211.035	-226.5218	76	14	5	8916	1	39	37
P-U	0.0	0.0	-0.0056	-0.0056	2	0	0	5	0	0	1
P-V	0.0	12.0095	-7.0057	5.0037	11	0	0	431	0	0	6
Q-Z	-38.9746	-30.1308	-164.014	-233.1194	101	44	4	9283	8	61	58
R-W	-5.323	-31.4335	-22.5703	-59.3268	18	2	1	855	1	5	9
U-V	-12.687	-12.2429	-196.119	-221.0489	89	45	8	9823	0	17	33

Interface residues

• 0-8: ARG550, GLN358, LYS398, SER378
• 0-Q: 7201CB7.2219, ALA20, ARG10Q, ARG110, ARG82Q, ASN120, GLU80Q, GLY60, GLY80, GLY84Q, GLY86Q, HIS30, HIS309, LEU70, LEU79Q, LYS11Q, LYS40, LYS50, LYS77Q, LYS85Q, LYS87Q, MET83Q, PRO78Q, SER90, THR100, VAL81Q
• 0-S: ARG15S, ARG23S, ARG720, ASN500, ASP42S, GLU43S, GLY480, ILE18S, LEU620, LEU750, LYS490, THR21S, TYR780, VAL510
• 2-X: ALA10X, ALA392, ALA42X, ALA46X, ALA4X, ALA91X, ARG262, ARG302, ARG362, ASP6X, GLN382, GLU272, GLU312, GLU342, GLY422, GLY94X, HIS31X, ILE412, ILE572, ILE89X, ILE8X, LEU13X, LEU322, LEU442, LEU92X, LEU9X, LYS282, LYS292, LYS48X, LYS542, MET332, PHE28X, PHE372, PHE47X, PRO11X, SER402, THR3X, THR45X, TRP29X, TYR18X, TYR26X, TYR5X, VAL12X, VAL252, VAL30X, VAL43X, VAL7X
• 4-G: ALA110G, ALA124, ALA61G, ALA6G, ARG113G, ARG118G, ARG134, ARG95G, ARG96G, ARG98G, ASN108G, ASN204, ASP116G, ASP4G, ASP97G, CYS164, CYS364, CYS394, GLN58G, GLN66G, GLU104G, GLU143G, GLU234, GLU304, GLU34, GLU344, GLU59G, GLY65G, HIS404, HIS64, ILE101G, ILE140G, ILE144, ILE144G, ILE154, ILE224, ILE314, ILE54, ILE63G, LEU106G, LEU107G, LEU111G, LEU3G, LEU60G, LEU62G, LEU7G, LEU94, LEU94G, LYS105G, LYS182G, LYS24, LYS284, LYS384, LYS67G, LYS84, MET14, MET99G, PHE102G, PHE117G, PHE141G, PHE424, PRO112G, PRO114, PRO142G, PRO179G, PRO414, PRO68G, PRO74, SER264, SER374, THR145G, THR244, THR274, THR444, THR64G, THR93G, TRP100G, TYR146G, TYR254, TYR324, TYR434, VAL104, VAL109G, VAL334, VAL354, VAL5G, VAL92G
• 5-R: ALA101R, ALA112R, ALA535, ARG103R, ARG105R, ARG33R, ARG555, ARG96R, CYS465, GLU102R, GLU115R, GLU118R, GLU595, GLY32R, GLY505, HIS31R, HIS435, ILE34R, LEU100R, LEU111R, LEU113R, LEU116R, LEU305, LEU98R, LYS405, LYS565, LYS99R, MET395, PRO415, PRO425, PRO475, THR35R, THR445, TYR515, TYR525, VAL114R, VAL117R, VAL455, VAL97R
• 5-U: ALA145, ARG155, GLY26U, LEU27U, LYS105, LYS135, LYS30U, LYS34U, LYS95, SER125, TRP25U
• 5-W: ALA245, ALA25, ALA32W, ALA385, ARG15W, ARG165, ARG18W, ARG195, ARG205, ARG33W, ARG37W, ARG92W, ASN34W, ASN40W, ASP175, ASP22W, CYS465, GLU30W, GLU31W, GLU485, GLU595, GLY43W, HIS235, ILE24W, ILE35W, LEU19W, LEU23W, LEU255, LEU305, LEU36W, LYS16W, LYS27W, LYS375, LYS405, LYS41W, MET395, PRO275, PRO285, PRO325, PRO415, PRO475, THR265, THR295, THR39W, THR445, TYR38W, VAL17W, VAL20W, VAL21W, VAL315
• 6-8: ALA226, ASN266, ASN338, GLN358, GLU126, GLU246, HIS318, ILE418, ILE546, LEU106, LEU116, LEU328, LEU96, LYS256, LYS368, LYS86, SER378, THR236, TRP348
• 7-F: ALA58F, LYS377, SER60F
• 7-W: ARG37, ARG90W
• 7-X: ARG477, ARG60X, ARG68X, ARG97, ASP75X, GLY61X, LYS487, LYS63X, LYS72X, TRP407, TYR69X
• 8-P: ALA108, ALA248, ALA518, ALA558, ARG138, ARG308, ARG468, ARG49P, ARG50P, ARG55P, ARG578, ARG61P, ARG65P, ASP47P, GLN68P, GLU52P, GLU548, GLU568, GLY288, GLY458, GLY66P, GLY69P, GLY98, HIS78, ILE168, ILE588, LEU328, LEU59P, LEU608, LEU618, LEU62P, LYS118, LYS128, LYS158, LYS268, LYS298, LYS448, LYS478, LYS528, LYS58, LYS598, LYS64P, LYS88, MET258, MET48, MET60P, MET67P, PHE51P, PRO48P, PRO538, PRO63P, THR278, THR57P, THR58P, THR68, VAL148, VAL228, VAL238, VAL498
• 9-H: ASN299, GLU289, LEU171H, LYS153H, LYS339, PRO309, VAL169H
• 9-Q: ARG119Q, GLU116Q, HIS123Q, ILE120Q, LYS89, SER69
• E-N: ARG149E, GLY153E, GLY77N, GLY80N, GLY81N, LYS152E, LYS154E, PRO79N, SER76N, TYR151E, TYR75N, TYR78N, VAL150E
• E-O: ALA20E, ARG13E, ARG16E, ARG19E, ARG71O, ASP18E, ASP73O, GLY74O, ILE14E, LYS70O, PHE15E, PRO22E, PRO72O, SER75O, VAL21E
• E-R: ALA114E, ALA162E, ARG111E, ARG2R, GLY110E, GLY112E, GLY161E, HIS3R, LYS109E, LYS118E, LYS5R, PHE113E, PRO191E, SER108E, TYR160E
• E-T: ALA20E, ALA5T, ARG13E, ARG13T, ARG16E, ARG19E, ARG39T, ARG3T, ARG53T, ARG76E, ASN180E, ASN192E, ASN2T, ASN55T, ASN58T, ASP174E, ASP17E, ASP18E, GLN54E, GLU11T, GLU178E, GLU179E, GLY10E, GLY193E, GLY29E, GLY4T, GLY6E, HIS79T, ILE14E, ILE176E, ILE26E, ILE75T, ILE7T, LEU181E, LEU182E, LEU183E, LEU27E, LEU52E, LEU6T, LEU78T, LEU82T, LEU9T, LYS33T, LYS8T, MET11E, MET1T, PHE15E, PHE51E, PHE57T, PHE76T, PRO22E, PRO53E, PRO77T, PRO81T, SER12T, SER80T, THR12E, THR24E, THR59T, THR60T, TYR14T, TYR32T, VAL10T, VAL15T, VAL173E, VAL21E, VAL23E, VAL25E, VAL34T, VAL7E, VAL9E
• F-P: ALA113F, ALA12P, ARG117F, ARG119F, ARG15P, ARG16P, ARG188F, ARG18P, ARG38F, ARG7P, ARG95F, ASN13P, ASN29F, ASN9P, ASP116F, ASP185F, ASP5P, GLU120F, GLU190F, GLU35F, GLY11P, HIS31F, ILE186F, ILE28F, LEU32F, LEU33F, LEU41F, LEU6P, LYS122F, LYS14P, LYS17P, MET112F, PRO10P, PRO30F, PRO8P, THR189F, TRP34F, TYR184F, TYR97F, VAL183F, VAL187F, VAL36F, VAL37F
• F-U: ALA49F, ARG3U, ARG45F, GLY91F, PRO2U, PRO92F, THR51F, TYR97F, VAL88F
• K-L: ALA61K, ALA75L, ALA93L, ARG63K, ASN33K, ASP102L, ASP55L, ASP62K, GLU36K, GLU82L, GLU96L, GLY77L, GLY79L, GLY97L, LEU78L, LEU94L, LYS2K, LYS95L, PHE65K, SER64K, SER99L, THR66K, THR76L, TYR60K, VAL98L
• K-Z: ARG112Z, ARG93K, GLU94K, GLY92K, LYS90K, PRO91K, VAL111Z
• N-U: ALA67U, ALA68U, ALA96U, ALA99U, ARG101U, ARG12N, ARG35N, ARG39N, ARG59U, ARG64U, ARG70U, ARG92U, ASN45N, ASN66U, ASN94U, ASP41N, ASP56U, ASP97U, CYS69U, GLN71U, GLY36N, HIS38N, ILE62U, ILE65U, LEU60U, LEU95U, LEU98U, LYS2N, LYS37N, LYS7N, LYS93U, MET1N, MET48N, PHE106U, PHE57U, PRO103U, PRO40N, PRO44N, PRO6N, THR32N, THR3N, THR43N, TRP42N, TRP61U, TYR4N, VAL100U, VAL46N, VAL5N, VAL63U
• N-V: ARG13V, ARG21V, GLN11V, ILE4V, LEU18V, LEU20V, LYS10V, LYS19V, LYS2N, MET1N, TYR12V, TYR4N, VAL14V, VAL22V, VAL5V
• O-T: ALA103O, ALA118O, ALA11O, ALA76O, ALA83O, ARG103T, ARG104O, ARG107O, ARG41T, ARG51T, ARG64O, ARG64T, ARG71O, ARG74T, ARG78O, ASN104T, ASN82O, ASP44T, ASP73O, ASP80O, ASP81O, GLN43T, GLU105O, GLU108O, GLU120O, GLU36T, GLU46T, GLU68O, GLU73T, GLU9O, GLY100O, GLY37T, GLY69T, GLY71T, GLY74O, HIS79T, ILE50T, ILE69O, ILE75T, ILE77O, LEU122O, LEU78T, LYS33T, LYS35T, LYS65T, LYS66O, LYS70O, PHE45T, PHE61T, PHE76T, PHE79O, PHE99O, PRO101O, PRO119O, PRO72O, PRO77T, PRO81T, SER31T, SER67T, SER75O, SER80T, THR60T, THR62T, THR65O, TYR100T, TYR32T, TYR68T, VAL102O, VAL115O, VAL121O, VAL34T, VAL63O, VAL63T, VAL66T, VAL70T, VAL72T
• P-U: ARG36U, GLY26P
• P-V: ALA31P, ARG82V, ARG83V, GLN80V, GLY26P, GLY28P, HIS27P, SER25P, THR30P, THR32P, TYR81V
• Q-Z: ALA107Q, ALA136Q, ALA140Q, ALA173Z, ALA20Q, ALA28Q, ALA36Q, ALA53Q, ARG101Q, ARG122Z, ARG133Q, ARG134Q, ARG49Z, ARG51Q, ARG56Q, ARG59Q, ARG60Q, ARG67Q, ARG72Z, ARG79Z, ARG80Z, ARG81Z, ARG82Z, ASN75Z, ASP123Z, ASP135Q, ASP138Q, ASP179Z, ASP25Q, ASP31Q, ASP45Z, ASP77Z, GLN118Z, GLN141Q, GLN50Z, GLN73Z, GLU119Z, GLU139Q, GLU178Z, GLU181Z, GLU38Q, GLY100Q, GLY108Q, GLY115Z, GLY19Q, GLY23Q, GLY24Q, GLY30Q, GLY33Q, GLY61Q, GLY62Q, HIS121Z, HIS54Z, HIS57Q, ILE120Z, ILE131Q, ILE53Z, ILE64Q, LEU117Z, LEU125Z, LEU183Z, LEU37Q, LEU76Z, LYS130Q, LYS182Z, LYS18Q, LYS22Q, LYS63Q, LYS78Z, LYS98Q, MET54Q, PHE104Z, PHE29Q, PHE44Z, PHE48Z, PHE58Q, PHE65Q, PRO176Z, PRO177Z, PRO39Q, PRO83Z, PRO99Q, SER52Z, THR21Q, TYR137Q, TYR26Q, TYR99Z, VAL102Q, VAL106Q, VAL109Q, VAL116Z, VAL132Q, VAL174Z, VAL175Z, VAL180Z, VAL27Q, VAL35Q, VAL52Q, VAL55Q, VAL71Z, VAL74Z
• R-W: ALA101R, ALA109R, ARG103R, ARG104R, ARG105R, ARG37W, ARG42W, ASN40W, ASP107R, GLU102R, GLY106R, GLY108R, LEU100R, LYS41W, PRO110R, THR39W, TYR38W, TYR45W
• U-V: ALA107U, ALA3V, ALA41U, ALA42U, ALA46U, ALA48U, ALA77V, ALA86U, ALA96U, ARG101U, ARG112U, ARG13V, ARG36U, ARG50U, ARG53U, ARG82V, ARG83V, ARG92U, ASN44U, ASN94U, ASP91U, ASP97U, GLN104U, GLN11V, GLU102U, GLU108U, GLU15V, GLU37U, GLU43V, GLU89U, GLY41V, GLY42V, GLY43U, GLY48V, GLY87U, GLY8V, GLY9V, HIS87V, ILE17U, ILE4V, ILE70V, ILE88U, LEU109U, LEU20U, LEU38V, LEU39U, LEU39V, LEU40V, LEU71V, LEU95U, LEU98U, LYS10V, LYS16U, LYS44V, LYS51U, LYS54U, LYS6V, LYS74V, LYS76V, LYS84V, LYS85V, LYS93U, MET1V, PHE106U, PHE2V, PHE40U, PHE75V, PRO103U, PRO50V, SER73V, THR38U, THR45V, THR49V, THR7V, TRP61U, TYR12V, TYR45U, TYR47U, TYR81V, VAL105U, VAL14V, VAL37V, VAL46V, VAL47V, VAL51V, VAL52V, VAL5V, VAL72V, VAL90U