2VT4

turkey beta1 adrenergic receptor with stabilising mutations and bound cyanopindolol

• Total interactions analyzed: 6
• Total true interactions: 4
• Strongest Interaction:
  • Chains: B-D
  • Int. Res.: 55
  • Norm. En. per Res.: -3.1408
• Hub Node: B(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	27.8136	-101.175	-73.3614	88	5	10	6038	0	3	4
B-C	0.0	0.0	-3.8822	-3.8822	13	0	0	211	0	1	0
B-D	-16.045	-49.8777	-106.823	-172.7457	55	6	1	4424	3	4	5
C-D	0.0	26.3019	-99.0843	-72.7824	85	2	9	5874	0	3	4

Interface residues

• A-B: ALA167A, ALA167B, ALA170A, ALA170B, ALA206A, ALA206B, ALA208A, ALA208B, ALA210A, ALA210B, ARG148A, ARG148B, ARG157A, ARG157B, ARG205A, ARG205B, ASN204A, ASN204B, ASN316B, CYS163A, CYS163B, GLU130A, GLU130B, ILE137A, ILE137B, ILE161A, ILE161B, ILE168A, ILE168B, ILE177A, ILE177B, ILE209A, ILE209B, ILE213A, ILE213B, ILE214A, ILE214B, ILE218A, ILE218B, ILE222A, ILE222B, LEU141A, LEU152A, LEU152B, LEU171A, LEU171B, LEU175A, LEU175B, LEU221A, LEU221B, LEU319B, MET178A, MET179A, MET179B, PHE174A, PHE174B, PHE225A, PHE315A, PHE315B, PRO176A, PRO176B, PRO219A, PRO219B, SER151B, SER169A, SER169B, SER173A, SER173B, SER211A, SER211B, THR164A, THR164B, TRP166A, TRP166B, TRP181A, TRP181B, TYR207A, TYR207B, TYR217A, VAL134B, VAL160A, VAL160B, VAL165A, VAL165B, VAL172A, VAL172B, VAL314A, VAL314B
• B-C: ALA170C, ASP186B, GLN188B, GLN194B, LEU113C, LEU116C, LEU175C, LEU190B, LYS191B, MET178C, PHE112C, PHE174C, PRO187B
• B-D: ALA189D, ALA42B, ARG104B, ARG183D, ASP184D, ASP186D, ASP195B, ASP195D, CYS114D, CYS192D, CYS198B, GLN194B, GLN194D, GLN39B, GLU115D, GLU185D, GLU41B, GLY105B, GLY110B, GLY110D, GLY197B, GLY197D, HIS180D, ILE177D, LEU108B, LEU108D, LEU113B, LEU113D, LEU116D, LEU190D, LYS191B, LYS191D, MET178D, MET179D, PHE112B, PHE112D, PHE97B, PRO176D, PRO187D, PRO196B, PRO196D, PRO96B, SER111B, SER111D, SER45B, THR100B, THR106B, TRP107B, TRP107D, TRP109B, TRP109D, TRP181D, TRP182D, TYR193D, VAL103B
• C-D: ALA167C, ALA167D, ALA170C, ALA170D, ALA206C, ALA206D, ALA208D, ALA210C, ALA210D, ARG148C, ARG148D, ARG157C, ARG157D, ARG205C, ARG205D, ASN204C, ASN204D, CYS133C, CYS163C, CYS163D, GLU130C, GLU130D, ILE137C, ILE137D, ILE161C, ILE161D, ILE168C, ILE168D, ILE177C, ILE177D, ILE209C, ILE209D, ILE213C, ILE213D, ILE214C, ILE214D, ILE218C, ILE218D, ILE222C, ILE222D, LEU141C, LEU141D, LEU152C, LEU152D, LEU171C, LEU171D, LEU175C, LEU175D, LEU221C, LEU221D, MET178D, MET179C, MET179D, PHE174C, PHE174D, PHE225D, PHE315C, PHE315D, PRO176C, PRO176D, PRO219C, PRO219D, SER169C, SER169D, SER173C, SER173D, SER211C, SER211D, THR164C, THR164D, TRP166C, TRP166D, TRP181C, TRP181D, TYR207C, TYR207D, VAL134C, VAL160C, VAL160D, VAL165C, VAL165D, VAL172C, VAL172D, VAL314C, VAL314D