2VSP

crystal structure of the fourth pdz domain of pdz domain- containing protein 1

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: A-D
  • Int. Res.: 45
  • Norm. En. per Res.: -3.4885
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-31.8187	24.1435	-57.3966	-65.0718	37	5	0	2891	3	16	23
A-C	-3.4511	-8.512	-28.504	-40.467	32	2	0	1457	0	14	14
A-D	-12.6017	-62.1228	-82.2601	-156.9845	45	4	1	3660	4	8	7
B-C	-4.7183	-50.8163	-85.0157	-140.5504	43	0	1	3599	2	7	5
B-D	-2.5208	-7.3999	-23.7944	-33.715	35	0	0	1409	0	16	15

Interface residues

• A-B: ARG442A, ARG442B, ASN427A, ASN427B, ASN430A, ASN430B, ASP433A, ASP433B, ASP441A, ASP441B, GLU425A, GLU434A, GLU434B, GLU437A, GLU437B, GLY428A, GLY428B, GLY447A, GLY447B, LEU432A, LEU432B, LYS438A, LYS438B, PRO435A, PRO435B, SER445A, SER445B, SER446A, SER446B, VAL426A, VAL426B, VAL429A, VAL429B, VAL431A, VAL431B, VAL439A, VAL439B
• A-C: ARG442A, ARG442C, ASN386A, ASN427C, ASN430C, ASP433C, ASP441A, ASP441C, GLN444A, GLU385A, GLU434C, GLU437A, GLY387A, GLY428C, GLY447A, GLY447C, HIS391A, ILE443A, LYS383A, LYS438C, LYS448A, PRO435C, SER445A, SER445C, SER446A, SER446C, TYR388A, TYR436A, VAL426C, VAL429C, VAL431C, VAL440A
• A-D: ALA415A, ALA415D, ARG380A, ARG380D, ASN427A, ASN427D, ASN430A, ASN430D, ASN449A, ASN449D, CYS379A, CYS379D, GLU425A, GLU425D, GLY428A, GLY428D, GLY447A, GLY447D, ILE424A, ILE424D, LEU378A, LEU378D, LEU381A, LEU381D, LEU452A, LEU452D, LEU453A, LEU453D, LYS377A, LYS377D, LYS448A, LYS448D, PRO376A, PRO376D, SER446A, SER446D, THR451A, THR451D, VAL426A, VAL426D, VAL429A, VAL429D, VAL450A, VAL450D, VAL454D
• B-C: ALA415B, ALA415C, ARG380B, ARG380C, ASN427B, ASN427C, ASN430B, ASN430C, ASN449B, ASN449C, CYS379B, CYS379C, GLU425B, GLU425C, GLY428B, GLY428C, GLY447B, GLY447C, ILE424B, ILE424C, LEU378B, LEU378C, LEU381B, LEU381C, LEU452B, LEU452C, LEU453B, LEU453C, LYS377B, LYS377C, LYS448B, PRO376C, SER446B, SER446C, THR451B, THR451C, VAL426B, VAL426C, VAL429B, VAL429C, VAL450B, VAL450C, VAL454C
• B-D: ARG442B, ARG442D, ASN386B, ASN427D, ASN430D, ASP433D, ASP441B, ASP441D, GLN444B, GLU385B, GLU434D, GLU437B, GLY387B, GLY428D, GLY447B, GLY447D, HIS391B, ILE443B, ILE443D, LYS383B, LYS438B, LYS438D, LYS448B, LYS448D, PRO435D, SER445B, SER445D, SER446B, SER446D, TYR388B, TYR436B, VAL426D, VAL429D, VAL431D, VAL440B